Biochemistry Of Signal Transduction And Regulation
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Biochemistry Of Signal Transduction And Regulation
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Author : Gerhard Krauss
language : en
Publisher: John Wiley & Sons
Release Date : 2014-02-14
Biochemistry Of Signal Transduction And Regulation written by Gerhard Krauss and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-14 with Science categories.
Originally based on a graduate course taught by the author, this true classic has once again been extensively updated to incorporate key new findings in biological signaling. With over half of the content re-written, plus 70 brand new and 50 revised figures, this is the most up-to-date textbook on signaling available anywhere. Thanks to its clear structure, hundreds of illustrative drawings, as well as chapter introductions and newly added study questions, this text excels as a companion for a course on biological signaling, and equally as an introductory reference to the field for students and researchers. Generations of students and junior researchers have relied on "the Krauss" to find their way through the bewildering complexity of biological signaling pathways.
Biochemistry Of Signal Transduction And Regulation
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Author : Gerhard Krauss
language : en
Publisher: John Wiley & Sons
Release Date : 2006-03-06
Biochemistry Of Signal Transduction And Regulation written by Gerhard Krauss and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-06 with Science categories.
This all-new edition of a classic text has been thoroughly revised to keep pace with the rapid progress in signal transduction research. With didactic skill and clarity the author relates the observed biological phenomena to the underlying biochemical processes. Directed to advanced students, teachers, and researchers in biochemistry and molecular biology, this book describes the molecular basis of signal transduction, regulated gene expression, the cell cycle, tumorigenesis and apoptosis. "Provides a comprehensive account of cell signaling and signal transduction and, where possible, explains these processes at the molecular level" (Angewandte Chemie) "The clear and didactic presentation makes it a textbook very useful for students and researchers not familiar with all aspects of cell regulation." (Biochemistry) "This book is actually two books: Regulation and Signal Transduction." (Drug Research)
Biochemistry Of Signal Transduction And Regulation
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Author : Gerhard Krauss
language : en
Publisher: Wiley-VCH
Release Date : 2005-07-27
Biochemistry Of Signal Transduction And Regulation written by Gerhard Krauss and has been published by Wiley-VCH this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-07-27 with Science categories.
Intracellular signal transduction, regulation of cellular activities, tumor formation, apoptosis - how do they work? These questions have become a central topic in Biology and Biological Chemistry. The importance of this field is mirrored in the 1999 Nobel price for Physiology that went to G. Blobel for his findings in protein transport regulation. Over the last decade there has been great progress in the understanding of the molecular basis of signal transduction, and many facts are now basic knowledge for every medicinal chemist, biochemist, and biologist. Since an integral description of cellular regulation and signal transduction is scarcely covered in textbooks, this book fills a real gap. Starting from the principles of gene regulation and regulation of enzyme activity, the topics of this book cover function, structure, and integral construction of signalling pathways plus a detailed description of the various types of carriers such as second messengers, protein kinases, and transmembrane receptors. Central cellular processes like cell cylce regulation, oncogenesis and apoptosis are discussed in light of the properties of the signalling molecules involved. With didactic skill and clarity the author relates the observed biological phenomena to the underlying biochemical processes. The book is actually two books: Regulation and Signal Transduction.
Signal Transduction
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Author : Carl-Henrik Heldin
language : en
Publisher: Garland Science
Release Date : 1996
Signal Transduction written by Carl-Henrik Heldin and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Cell physiology categories.
Signal Transduction was published in association with The International Union of Biochemistry and Molecular Biology. In a series of twenty-three short chapters, leading researchers provide cutting-edge reviews of signal transduction, and form cell membrane receptors through to gene regulation. Written for those with a basic understanding of molecular and cell biology, the book will be of particular interest to graduate students and researchers who need to grasp the principles of signal transduction.
The Biochemistry Of Cell Signalling
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Author : Ernst J. M. Helmreich
language : en
Publisher: Oxford University Press, USA
Release Date : 2001
The Biochemistry Of Cell Signalling written by Ernst J. M. Helmreich and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Language Arts & Disciplines categories.
A comprehensive study of the principles of cell signalling, concentrating on the structural and mechanistic aspects. The book is divided into four parts describing the machinery of signal transduction, the implementation of the signalling cascades focussing on the effect on gene transcription, the globular cellular regulatory programs, and the loss of regulatory control and its consequences with repsect to the molecular basis of cancer. There are well over 200 figures, many in 3-D representations.
Signal Transduction
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Author : Ijsbrand M. Kramer
language : en
Publisher: Academic Press
Release Date : 2015-10-23
Signal Transduction written by Ijsbrand M. Kramer and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-23 with Science categories.
A reference on cellular signaling processes, the third edition of Signal Transduction continues in the tradition of previous editions, in providing a historical overview of how the concept of stimulus-response coupling arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, growth factors and adhesion molecules. In a new chapter, an introduction to signal transduction, the book provides a concise overview of receptor mechanisms, from receptor – ligand interactions to post-translational modifications operational in the process of bringing about cellular changes. The phosphorylation process, from bacteria to men, is discussed in detail. Signal transduction third edition further elaborates on diverse signaling cascades within particular contexts such as muscle contraction, innate and adaptive immunity, glucose metabolism, regulation of appetite, oncogenic transformation and cell fate decision during development or in stem cell niches. The subjects have been enriched with descriptions of the relevant anatomical, histological, physiological or pathological condition. In-depth insight into a subject central to cell biology and fundamental to biomedicine, including the search for novel therapeutic interventions Essential signaling events embedded in rich physiological and pathological contexts Extensive conceptual colour artwork to assist with comprehension of key topics Special emphasis on how molecular structure determines protein function and subcellular localization Employment of unambiguous protein names (symbols) in agreement with leading protein- and gene databases, allowing the learner to extend his/her exploration on the web
Calmodulin And Signal Transduction
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Author : Linda J. Van Eldik
language : en
Publisher: Academic Press
Release Date : 2012-12-02
Calmodulin And Signal Transduction written by Linda J. Van Eldik and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
This book focuses on emerging themes in the molecular mechanisms of calcium signal transduction through calmodulin-regulated pathways. It provides the reader with selected examples and experimental precedents that underlie current models of cell regulation through calmodulin-regulated pathways and their linkage with other regulatory pathways. Highlights: * Molecular mechanisms of calcium signal transduction through calmodulin-regulated enzymes * Selected case studies and precedents related to molecular mechanisms * Protein-protein recognition between calmodulin and the enzymes it regulates * Cross-talk and interdigitation with other signal transduction pathways
Biochemistry Of Signal Transduction In Myocardium
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Author : Jos M.J. Lamers
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Biochemistry Of Signal Transduction In Myocardium written by Jos M.J. Lamers and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The chapters in this volume are the Proceedings of the Satellite Symposium of the XVIth World Congress of the International Society for Heart Research on `Signal Transduction in Normal and Diseased Myocardium' which was held in Rotterdam at the Faculty of Medicine & Health Sciences of the Erasmus University, June 30 and July 1, 1995. Diverse and distinct auto-, para-, and endocrine stimuli arriving at the surface of endothelium, smooth muscle cells, cardiomyocytes and fibroblasts within the myocardium, engage cell type-specific receptors, which lead to transmission of signals across the cell plasma membrane and result in the production and activation of second messengers. The most common mechanism by which these second messengers function is via direct or indirect activation of specific protein kinases. The current challenge for scientists is to identify the specific substrates (e.g. metabolic enzymes, Ca2+-regulating proteins, transcription and mitotic factors) for the many protein kinases, to elucidate the biological significance of the cell type-specific expression heterogeneity of signalling proteins (e.g. membrane receptors, isoenzymes of protein kinase C, G-proteins) and to unravel the cross-talk interaction between the signalling systems (e.g. phospholipase C with adenylate cyclase and phospholipase C with phospholipase D). The multiplicity of receptor types, G-proteins, effector proteins, second messengers and protein kinases, their substrate proteins and the `cross-talk' interactions in the myocardium raises fundamental questions about the mechanisms that ensure the precision and timing of the myocardial responses to hormonal and pharmacological stimuli. This book provides an up-to-date source of information for all scientists and clinicians interested in the mechanisms by which external signals are transmitted to the interior and regulation of a variety of physiological, pathological and pharmacological responses.
Cellular Signal Processing
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Author : Friedrich Marks
language : en
Publisher: Garland Science
Release Date : 2017-05-17
Cellular Signal Processing written by Friedrich Marks and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-17 with Medical categories.
Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.
Regulation Of Signal Transduction In Human Cell Research
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Author : Nariyoshi Shinomiya
language : en
Publisher: Springer
Release Date : 2018-02-15
Regulation Of Signal Transduction In Human Cell Research written by Nariyoshi Shinomiya and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-15 with Medical categories.
This volume focuses on the relationship between the regulation of signal transduction and disease mechanisms, and discusses how the dysregulation of intracellular signals cause diseases, cell death, carcinogenesis, and other disorders. Growth, survival, transformation, and metabolic activities at the cellular level are regulated by various intracellular signal transduction pathways. Sources that stimulate intracellular signals include intracellular stresses and signal regulators/modulators, as well as extracellular growth factors. Recent studies on signal transduction analysis using animal and human cell lines have revealed how the intracellular signals are regulated and why their dysregulation leads to pathological states such as tumorigenesis, metabolic diseases, cell death, and so on. This book highlights several important key molecules and intracellular signaling pathways such as microRNA, the TGF-beta signaling pathway, the Wnt signaling pathway and MET signaling pathway as topical and highly relevant issues in human cell research related to signal transduction. In addition to assessing the pathogenic role of these signaling pathways, it focuses on the molecular design of small molecule regulators/inhibitors of said pathways, one of the most important approaches in this area. This book offers a valuable guide, helping not only research scientists but also clinicians to understand how the dysregulation of intracellular signals leads to diseases.