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Biodegradable Polymer Based Scaffolds For Bone Tissue Engineering


Biodegradable Polymer Based Scaffolds For Bone Tissue Engineering
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Biodegradable Polymer Based Scaffolds For Bone Tissue Engineering


Biodegradable Polymer Based Scaffolds For Bone Tissue Engineering
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Author : naznin sultana
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-15

Biodegradable Polymer Based Scaffolds For Bone Tissue Engineering written by naznin sultana and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-15 with Technology & Engineering categories.


This book addresses the principles, methods and applications of biodegradable polymer based scaffolds for bone tissue engineering. The general principle of bone tissue engineering is reviewed and the traditional and novel scaffolding materials, their properties and scaffold fabrication techniques are explored. By acting as temporary synthetic extracellular matrices for cell accommodation, proliferation, and differentiation, scaffolds play a pivotal role in tissue engineering. This book does not only provide the comprehensive summary of the current trends in scaffolding design but also presents the new trends and directions for scaffold development for the ever expanding tissue engineering applications.



Polymer Based Systems On Tissue Engineering Replacement And Regeneration


Polymer Based Systems On Tissue Engineering Replacement And Regeneration
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Author : Rui L. Reis
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Polymer Based Systems On Tissue Engineering Replacement And Regeneration written by Rui L. Reis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


Biodegradable, polymer-based systems are playing an increasingly pivotal role in tissue engineering replacement and regeneration. This type of biology-driven materials science is slated to be one of the key research areas of the 21st century. The following aspects are crucial: the development of adequate human cell culture to produce the tissues in adequate polymer scaffold materials; the development of culture technology with which human tissues can be grown ex-vivo in 3D polymer matrices; the development of material technology for producing the degradable, 3D matrices, having mechanical properties similar to natural tissue. In addressing these and similar problems, the book contains chapters on biodegradable polymers, polymeric biomaterials, surface modification for controlling cell-material interactions, scaffold design and processing, biomimetic coatings, biocompatibility evaluation, tissue engineering constructs, cell isolation, characterisation and culture, and controlled release of bioactive agents.



Synthetic Biodegradable Polymer Scaffolds


Synthetic Biodegradable Polymer Scaffolds
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Author : Anthony Atala
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11

Synthetic Biodegradable Polymer Scaffolds written by Anthony Atala and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.


This body of work represents the first volume of a book series covering the field of tissue engineering. Tissue engineering, which refers to a category of therapeutic or diagnostic products and processes which are based upon a combination of living cells and biomaterials, was defined as a field only a few years ago (1988). Tissue engineering is an inherently interdisciplinary field, combining bioengineering, life sciences and clinical sciences. The definition of this area of work as the field of tissue engineering brought together scientists from multiple backgrounds who already were working toward the achievement of similar goals. Why a book series exclusively devoted to tissue engineering? The field of tissue engineering is heterogeneous. The cells involved in tissue engineering can be autologous, allogeneic or xenogeneic. The biomaterials utilized can be either naturally occurring, synthetic or a combination of both. The appli cation of the technology can be either for acute or permanent purposes. An attempt to cover the field of tissue engineering in a single volume, with the degree of detail necessary for individuals with different scientific back grounds and disciplines, would be a difficult task to accomplish, particularly when this field is just emerging and changing rapidly. Therefore, addressing different technologies within the field of tissue engineering, in a comprehen sive manner, is the main mission of this series of volumes. A stellar group of scientists has been brought together to form the editorial board of the series.



Materials For Biomedical Engineering Hydrogels And Polymer Based Scaffolds


Materials For Biomedical Engineering Hydrogels And Polymer Based Scaffolds
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Author : Alina-Maria Holban
language : en
Publisher: Elsevier
Release Date : 2019-03-20

Materials For Biomedical Engineering Hydrogels And Polymer Based Scaffolds written by Alina-Maria Holban and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-20 with Medical categories.


Materials for Biomedical Engineering: Hydrogels and Polymer-Based Scaffolds discusses the use of a wide variety of hydrogels as bioactive scaffolds in regenerative medicine, including updates on innovative materials and their properties. Various types of currently investigated scaffolding materials and hydrogels are discussed, as is their future roles and applications, the main techniques for scaffold fabrication, and their characterization procedures. Readers will be able to use this book as a guide for the selection of the best materials for a specific application. Provides a valuable resource of recent scientific progress, highlighting the most well-known applications of hydrogels as bioactive scaffolds in regenerative medicine Includes novel opportunities and ideas for developing or improving technologies in biomaterials, and in related biomedical industries Features at least 50% of references from the last 2-3 years



Studies Of Electrically Conducting Polymers And Biodegradable Polymers For Bone Tissue Engineering


Studies Of Electrically Conducting Polymers And Biodegradable Polymers For Bone Tissue Engineering
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Author : Jen-Chieh Wu
language : en
Publisher:
Release Date : 2009

Studies Of Electrically Conducting Polymers And Biodegradable Polymers For Bone Tissue Engineering written by Jen-Chieh Wu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.


Abstract: In this study, electrically conducting and biodegradable polymer scaffolds were fabricated and tested on bone cells in vitro and in the mice model. The experiments are discussed in Chapter 2 through Chapter 5. Electric field was found to have a positive effect on bone fracture healing. One of the major challenges for this project was to find the right materials to build scaffolds. The materials had to have electrical conductivity, biocompatibility, and processibility. Chapter 2 discusses block copolymers that were designed and synthesized by ring-opening polymerization. These copolymers consisted of polyaniline, polycaprolactone and polylactic acid. They were found to have good solubility in common organic solvents. Cell toxicity tests demonstrated that the copolymers also had good biocompatibility and biodegradability. Fabricating suitable scaffolds for bone cells was another challenge for this project. Chapter 3 discusses three engineering methods that were used to build scaffolds, including electrospinning, printing, and stamping. Polymer fibers were obtained using the electrospinning method. These fibers were soft, flexible, biocompatible, and suitable for soft-tissue engineering. Two-dimensional sulfonated polyaniline-based scaffolds were built with the printing method and then used in experiments, where bone cells were electrically stimulated. Three-dimensional polymer scaffolds were fabricated with the soft-lithography stamping method. These scaffolds with designed patterns had good mechanical properties and uniform shapes. All of these three types of scaffolds derived from the electrospinning, printing, and stamping methods demonstrated good biocompatibility. To evaluate the effect of an electric field on cell proliferation and differentiation, we carried out cell tests using three cells, including the human osteosarcoma (HOS) cells, mice preosteoblast MC3T3-E1 cells, and mice bone marrow stromal cells (BMSC). HOS cells were used to determine suitable electrical stimulating conditions. Chapter 4 discusses the HOS cell growth, the alkaline phosphatase activity, and the mineral deposition that were tested to evaluate the cell proliferation. We found that the best condition was alternate current (AC) with an amplitude of 400 mV and a frequency of 1 kHz. Chapter 5 discusses mice cells, preosteoblast MC3T3-E1 and bone marrow stromal cells that were tested. Both cells showed enhanced cell proliferation and increased alkaline phosphatase activity under electrical stimulation. Furthermore, they showed enhanced mineral deposition, which is a crucial feature of early-stage bone formation. These are important observations, because it is the first time that research has demonstrated that BMSC can differentiate into osteoblast on the biocompatible conducting polymer scaffolds with electrical stimulation. This may have great potential in future biomedical and therapeutic applications, such as facilitating the bone fracture healing process.



Natural Biopolymers In Drug Delivery And Tissue Engineering


Natural Biopolymers In Drug Delivery And Tissue Engineering
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Author : Rangasamy Jayakumar
language : en
Publisher: Elsevier
Release Date : 2023-08-24

Natural Biopolymers In Drug Delivery And Tissue Engineering written by Rangasamy Jayakumar and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-24 with Medical categories.


Natural Biopolymers in Drug Delivery and Tissue Engineering systematically examines a broad range of natural polymers and their applications in drug delivery and tissue engineering. The book thoroughly collates the most relevant and up-to-date research on natural biopolymers, covering a variety of key natural polymer types such as chitin, chitosan, alginate, guar gum and collagen. It is divided into two sections, covering drug delivery and tissue engineering applications. Each section focuses on natural biopolymers in the form of scaffolds, membranes, films, gels and nanoparticles, thus helping the reader select not only the most appropriate polymer type, but also the most relevant structure. This comprehensive resource is ideal for materials scientists, biomedical engineers, tissue engineers, pharmaceutical scientists and anyone interested in developing novel materials for biomedical applications. Covers both drug delivery and tissue engineering applications of natural biopolymers, helping bridge the gap between the two Details a range of natural polymer types, ensuring all relevant options are presented Discusses the benefits, challenges and clinical translation of natural biopolymers



Biodegradable Polymeric Nanocomposites


Biodegradable Polymeric Nanocomposites
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Author : Dilip Depan
language : en
Publisher: CRC Press
Release Date : 2015-10-22

Biodegradable Polymeric Nanocomposites written by Dilip Depan and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-22 with Medical categories.


How Can Polymers Constructed From Living Organisms Help Eliminate the Disposal Issue? A unique category of materials called biodegradable polymers could help remedy a growing environmental concern. Biodegradable Polymeric Nanocomposites: Advances in Biomedical Applications considers the potential of biodegradable polymers for use in biomedical appl



Synthetic Biodegradable Polymer Scaffolds


Synthetic Biodegradable Polymer Scaffolds
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Author : Anthony Atala
language : en
Publisher:
Release Date : 1997

Synthetic Biodegradable Polymer Scaffolds written by Anthony Atala and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Animal cell biotechnology categories.


Brings together articles from leading researchers in the field of the synthesis and properties of biodegradable polymers utilized in tissue engineering. It should provide guidance on potential new materials or applications in the tissue engineering field.



Bone Tissue Engineering On Biodegradable Polymers


Bone Tissue Engineering On Biodegradable Polymers
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Author : Chantal E. Holy
language : en
Publisher:
Release Date : 1999

Bone Tissue Engineering On Biodegradable Polymers written by Chantal E. Holy and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with categories.




Handbook Of Composites From Renewable Materials Biodegradable Materials


Handbook Of Composites From Renewable Materials Biodegradable Materials
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Author : Vijay Kumar Thakur
language : en
Publisher: John Wiley & Sons
Release Date : 2017-02-17

Handbook Of Composites From Renewable Materials Biodegradable Materials written by Vijay Kumar Thakur and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-17 with Technology & Engineering categories.


This unique multidisciplinary 8-volume set focuses on the emerging issues concerning synthesis, characterization, design, manufacturing and various other aspects of composite materials from renewable materials and provides a shared platform for both researcher and industry. The Handbook of Composites from Renewable Materials comprises a set of 8 individual volumes that brings an interdisciplinary perspective to accomplish a more detailed understanding of the interplay between the synthesis, structure, characterization, processing, applications and performance of these advanced materials. The Handbook comprises 169 chapters from world renowned experts covering a multitude of natural polymers/ reinforcement/ fillers and biodegradable materials. Volume 5 is solely focused on 'Biodegradable Materials'. Some of the important topics include but not limited to: Rice husk and its composites; biodegradable composites based on thermoplastic starch and talc nanoparticles; recent progress in biocomposites of biodegradable polymer; microbial polyesters: production and market; biodegradable and bioabsorbable materials for osteosynthesis applications; biodegradable polymers in tissue engineering; composites based on hydroxyapatite and biodegradable polylactide; biodegradable composites; development of membranes from biobased materials and their applications; green biodegradable composites based on natural fibers; fully biodegradable all-cellulose composites; natural fiber composites with bioderivative and/or degradable polymers; synthetic biodegradable polymers for bone tissue engineering; polysaccharides as green biodegradable platforms for building up electroactive composite materials; biodegradable polymer blends and composites from seaweeds; biocomposites scaffolds derived from renewable resources for bone tissue repair; pectin-based composites; recent advances in conductive composites based on biodegradable polymers for regenerative medicine applications; biosynthesis of PHAs and their biomedical applications; biodegradable soy protein isolate/poly(vinyl alcohol) packaging films; and biodegradability of biobased polymeric materials in natural environment.