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Bioinformatics And Human Genomics Research


Bioinformatics And Human Genomics Research
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Bioinformatics And Human Genomics Research


Bioinformatics And Human Genomics Research
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Author : Diego A. Forero
language : en
Publisher: CRC Press
Release Date : 2021-12-23

Bioinformatics And Human Genomics Research written by Diego A. Forero and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-23 with Science categories.


Advances in high-throughput biological methods have led to the publication of a large number of genome-wide studies in human and animal models. In this context, recent tools from bioinformatics and computational biology have been fundamental for the analysis of these genomic studies. The book Bioinformatics and Human Genomics Research provides updated and comprehensive information about multiple approaches of the application of bioinformatic tools to research in human genomics. It covers strategies analysis of genome-wide association studies, genome-wide expression studies and genome-wide DNA methylation, among other topics. It provides interesting strategies for data mining in human genomics, network analysis, prediction of binding sites for miRNAs and transcription factors, among other themes. Experts from all around the world in bioinformatics and human genomics have contributed chapters in this book. Readers will find this book as quite useful for their in silico explorations, which would contribute to a better and deeper understanding of multiple biological processes and of pathophysiology of many human diseases.



Bioinformatics And Human Genomics Research


Bioinformatics And Human Genomics Research
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Author : Diego A. Forero
language : en
Publisher: CRC Press
Release Date : 2021-12-22

Bioinformatics And Human Genomics Research written by Diego A. Forero and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-22 with Science categories.


Advances in high-throughput biological methods have led to the publication of a large number of genome-wide studies in human and animal models. In this context, recent tools from bioinformatics and computational biology have been fundamental for the analysis of these genomic studies. The book Bioinformatics and Human Genomics Research provides updated and comprehensive information about multiple approaches of the application of bioinformatic tools to research in human genomics. It covers strategies analysis of genome-wide association studies, genome-wide expression studies and genome-wide DNA methylation, among other topics. It provides interesting strategies for data mining in human genomics, network analysis, prediction of binding sites for miRNAs and transcription factors, among other themes. Experts from all around the world in bioinformatics and human genomics have contributed chapters in this book. Readers will find this book as quite useful for their in silico explorations, which would contribute to a better and deeper understanding of multiple biological processes and of pathophysiology of many human diseases.



Fueling Innovation And Discovery


Fueling Innovation And Discovery
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2012-08-02

Fueling Innovation And Discovery written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-02 with Mathematics categories.


The mathematical sciences are part of everyday life. Modern communication, transportation, science, engineering, technology, medicine, manufacturing, security, and finance all depend on the mathematical sciences. Fueling Innovation and Discovery describes recent advances in the mathematical sciences and advances enabled by mathematical sciences research. It is geared toward general readers who would like to know more about ongoing advances in the mathematical sciences and how these advances are changing our understanding of the world, creating new technologies, and transforming industries. Although the mathematical sciences are pervasive, they are often invoked without an explicit awareness of their presence. Prepared as part of the study on the Mathematical Sciences in 2025, a broad assessment of the current state of the mathematical sciences in the United States, Fueling Innovation and Discovery presents mathematical sciences advances in an engaging way. The report describes the contributions that mathematical sciences research has made to advance our understanding of the universe and the human genome. It also explores how the mathematical sciences are contributing to healthcare and national security, and the importance of mathematical knowledge and training to a range of industries, such as information technology and entertainment. Fueling Innovation and Discovery will be of use to policy makers, researchers, business leaders, students, and others interested in learning more about the deep connections between the mathematical sciences and every other aspect of the modern world. To function well in a technologically advanced society, every educated person should be familiar with multiple aspects of the mathematical sciences.



Essentials Of Genomics And Bioinformatics


Essentials Of Genomics And Bioinformatics
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Author : Christoph W. Sensen
language : de
Publisher: John Wiley & Sons
Release Date : 2008-09-26

Essentials Of Genomics And Bioinformatics written by Christoph W. Sensen and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-26 with Science categories.


Provides an overview of the rapidly evolving field of genomics with coverage of nucleic acid technologies, proteomics and bioinformatics. It includes chapters on applications in human health, agriculture and comparative genomics and also contains two chapters on the legal and ethical issues of genomics, a topic that is becoming increasingly important as genomics moves out of the laboratory into practical applications.



Cellular And Animal Models In Human Genomics Research


Cellular And Animal Models In Human Genomics Research
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Author :
language : en
Publisher: Academic Press
Release Date : 2019-07-30

Cellular And Animal Models In Human Genomics Research written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-30 with Medical categories.


Cellular and Animal Models in Human Genomics Research provides an indispensable resource for applying comparative genomics in the annotation of disease-gene associated variants that are identified by human genomic sequencing. The book presents a thorough overview of effective protocols for the use of cellular and animal modeling methods to turn lists of plausible genes into causative biomarkers. With chapters written by international experts, the book first addresses the fundamental aspects of using cellular and animal models in genetic and genomic studies, including in-depth examples of specific models and their utility, i.e., yeast, worms, flies, fish, mice and large animals. Protocols for properly conducting model studies, genomic technology, modeling candidate genes vs. genetic variants, integrative modeling, utilizing induced pluripotent stem cells, and employing CRISPR-Cas9 are also discussed in-depth. - Provides a thorough, accessible resource that helps researchers and students employ cellular and animal models in their own genetic and genomic studies - Offers guidance on how to effectively interpret the results and significance of genetic and genomic model studies for human health - Features chapters from international experts in the use of specific cellular and animal models, including yeast, worms, flies, fish, mice, and large animals, among other organisms



Bioinformatics For Geneticists


Bioinformatics For Geneticists
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Author : Michael R. Barnes
language : en
Publisher: John Wiley & Sons
Release Date : 2003-04-09

Bioinformatics For Geneticists written by Michael R. Barnes and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-04-09 with Computers categories.


Bioinformatics for Geneticists describes a step by step approach to key bioinformatics and genetic analysis procedures, based upon practical experience gained after many years of direct bioinformatics support for laboratory geneticists. It features detailed case studies of problems and analytical approaches that are specific to the needs of the genetics researcher. The book contains reviews of bioinformatics tools and genetic databases. Each chapter is written to capture the principles of analysis regardless of the tool used, thereby ensuring that the book stays relevant as new data and tools become available. As the first book specifically addressing the informatics requirements of geneticists, Bioinformatics for Geneticists is essential reading for all those engaged in genetic research and should prove indispensable for both the planning and analysis of such studies. * The book provides in-depth coverage of the underlying principles of both genetic and bioinformatic analysis which should make this book suitable for all students of genetics or bioinformatics. * The book takes a web-based approach to bioinformatics, suitable for both internet novices and more experienced web users. * The focus is on public software tools and databases freely available to all. * The editors and authors bring a broad range of experience from academic and industrial genetics research environments. * The book is accessible to individuals outside the immediate field of molecular genetics, e.g. statisticians, epidemiologists and physicians who wish to improve their knowledge of bioinformatics and genetics. * This is currently the only book specifically aimed at the bioinformatics needs and priorities of genetics researchers.



Human Genome Informatics


Human Genome Informatics
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Author : Christophe Lambert
language : en
Publisher: Academic Press
Release Date : 2018-08-02

Human Genome Informatics written by Christophe Lambert and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-02 with Medical categories.


Human Genome Informatics: Translating Genes into Health examines the most commonly used electronic tools for translating genomic information into clinically meaningful formats. By analyzing and comparing interpretation methods of whole genome data, the book discusses the possibilities of their application in genomic and translational medicine. Topics such as electronic decision-making tools, translation algorithms, interpretation and translation of whole genome data for rare diseases are thoroughly explored. In addition, discussions of current human genome databases and the possibilities of big data in genomic medicine are presented. With an updated approach on recent techniques and current human genomic databases, the book is a valuable source for students and researchers in genome and medical informatics. It is also ideal for workers in the bioinformatics industry who are interested in recent developments in the field. - Provides an overview of the most commonly used electronic tools to translate genomic information - Brings an update on the existing human genomic databases that directly impact genome interpretation - Summarizes and comparatively analyzes interpretation methods of whole genome data and their application in genomic medicine



Essentials Of Bioinformatics Volume I


Essentials Of Bioinformatics Volume I
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Author : Noor Ahmad Shaik
language : en
Publisher: Springer
Release Date : 2019-03-27

Essentials Of Bioinformatics Volume I written by Noor Ahmad Shaik and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-27 with Computers categories.


Bioinformatics is an integrative field of computer science, genetics, genomics, proteomics, and statistics, which has undoubtedly revolutionized the study of biology and medicine in past decades. It mainly assists in modeling, predicting and interpreting large multidimensional biological data by utilizing advanced computational methods. Despite its enormous potential, bioinformatics is not widely integrated into the academic curriculum as most life science students and researchers are still not equipped with the necessary knowledge to take advantage of this powerful tool. Hence, the primary purpose of our book is to supplement this unmet need by providing an easily accessible platform for students and researchers starting their career in life sciences. This book aims to avoid sophisticated computational algorithms and programming. Instead, it mostly focuses on simple DIY analysis and interpretation of biological data with personal computers. Our belief is that once the beginners acquire these basic skillsets, they will be able to handle most of the bioinformatics tools for their research work and to better understand their experimental outcomes. Unlike other bioinformatics books which are mostly theoretical, this book provides practical examples for the readers on state-of-the-art open source tools to solve biological problems. Flow charts of experiments, graphical illustrations, and mock data are included for quick reference. Volume I is therefore an ideal companion for students and early stage professionals wishing to master this blooming field.



Genomics And Bioinformatics


Genomics And Bioinformatics
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Author : Tore Samuelsson
language : en
Publisher: Cambridge University Press
Release Date : 2012-06-07

Genomics And Bioinformatics written by Tore Samuelsson and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-07 with Science categories.


With the arrival of genomics and genome sequencing projects, biology has been transformed into an incredibly data-rich science. The vast amount of information generated has made computational analysis critical and has increased demand for skilled bioinformaticians. Designed for biologists without previous programming experience, this textbook provides a hands-on introduction to Unix, Perl and other tools used in sequence bioinformatics. Relevant biological topics are used throughout the book and are combined with practical bioinformatics examples, leading students through the process from biological problem to computational solution. All of the Perl scripts, sequence and database files used in the book are available for download at the accompanying website, allowing the reader to easily follow each example using their own computer. Programming examples are kept at an introductory level, avoiding complex mathematics that students often find daunting. The book demonstrates that even simple programs can provide powerful solutions to many complex bioinformatics problems.



Mapping And Sequencing The Human Genome


Mapping And Sequencing The Human Genome
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 1988-01-01

Mapping And Sequencing The Human Genome written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-01-01 with Science categories.


There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.