Biological Aging
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Handbook Of The Biology Of Aging
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Author : Matt Kaeberlein
language : en
Publisher: Academic Press
Release Date : 2015-08-20
Handbook Of The Biology Of Aging written by Matt Kaeberlein and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-20 with Medical categories.
Handbook of the Biology of Aging, Eighth Edition, provides readers with an update on the rapid progress in the research of aging. It is a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology, and focuses on the trend of ‘big data’ approaches in the biological sciences, presenting new strategies to analyze, interpret, and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and the metabolomics methodologies applied to aging related problems. The book includes discussions on longevity pathways and interventions that modulate aging, innovative new tools that facilitate systems-level approaches to aging research, the mTOR pathway and its importance in age-related phenotypes, new strategies to pharmacologically modulate the mTOR pathway to delay aging, the importance of sirtuins and the hypoxic response in aging, and how various pathways interact within the context of aging as a complex genetic trait, amongst others. Covers the key areas in biological gerontology research in one volume, with an 80% update from the previous edition Edited by Matt Kaeberlein and George Martin, highly respected voices and researchers within the biology of aging discipline Assists basic researchers in keeping abreast of research and clinical findings outside their subdiscipline Presents information that will help medical, behavioral, and social gerontologists in understanding what basic scientists and clinicians are discovering New chapters on genetics, evolutionary biology, bone aging, and epigenetic control Provides a close examination of the diverse research being conducted today in the study of the biology of aging, detailing recent breakthroughs and potential new directions
Challenges Of Biological Aging
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Author : Edward J. Masoro
language : en
Publisher: Springer Publishing Company
Release Date : 2000-09-05
Challenges Of Biological Aging written by Edward J. Masoro and has been published by Springer Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-09-05 with Science categories.
This volume provides the non-biologist an overview of what is known about the physiological bases of aging. The author examines the many basic theories and emerging hypotheses underlying the molecular, cellular, and systemic processes involved in senescence. He addresses the normal physiological changes that characterize the aging phenotype, and also considers the role of many age-associated diseases in growing older. Masoro synthesizes a much-needed "unified theory" of biological aging to which explains how and why the body grows into the condition we call "old." This text is intended for gerontology students in training, as well as for human physiologists interested in gerontology.
Biological Aging
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Author : Trygve O. Tollefsbol
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-03
Biological Aging written by Trygve O. Tollefsbol and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-03 with Science categories.
This book investigates the various processes that are affected by the age of an organism. Several new tools for the analysis of biological aging have been introduced recently, and this volume provides methods and protocols for these new techniques in addition to its coverage of established procedures. Researchers seeking new technology and techniques will find this volume of tremendous benefit as they move towards new directions.
The Biology Of Human Ageing
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Author : Society for the Study of Human Biology
language : en
Publisher: Cambridge University Press
Release Date : 1986-03-20
The Biology Of Human Ageing written by Society for the Study of Human Biology and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986-03-20 with Medical categories.
This book discusses the findings of a joint symposium held in 1984 to consider human ageing and longevity from an interdisciplinary point of view.
Human Biological Aging
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Author : Glenda E. Bilder
language : en
Publisher: John Wiley & Sons
Release Date : 2016-04-04
Human Biological Aging written by Glenda E. Bilder and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-04 with Science categories.
Comprehension of the theories of aging requires rudimentary knowledge of oxidation and reduction reactions, protein function, cell organelles, mitosis, acquired immunity, and evolution, among other basic biological concepts. Without these fundamentals, students of biological aging struggle to learn the essentials of biological aging and how to appreciate the research advances in the field. Human Biological Aging: From Macromolecules To Organ-Systems is an introduction to human aging from the level of macromolecules to organ systems. Age changes in proteins, DNA, polysaccharides and lipids are discussed relative to known age-related alterations in structure and function produced by free radicals and oxidants. At the cellular level, age-dependent mechanisms that diminish organelle function are described. Cellular phenomena of replicative senescence apoptosis, autophagy and neuroplasticity are detailed as to their contribution to compromised cellular functions. Authored by a leader in the field, Human Biological Aging: From Macromolecules To Organ-Systems is an invaluable introduction for those studying human aging.
Biology Of Aging
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Author : Roger B. McDonald
language : en
Publisher: Garland Science
Release Date : 2019-06-07
Biology Of Aging written by Roger B. McDonald and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-07 with Science categories.
Biology of Aging, Second Edition presents the biological principles that have led to a new understanding of the causes of aging and describes how these basic principles help one to understand the human experience of biological aging, longevity, and age-related disease. Intended for undergraduate biology students, it describes how the rate of biological aging is measured; explores the mechanisms underlying cellular aging; discusses the genetic pathways that affect longevity in various organisms; outlines the normal age-related changes and the functional decline that occurs in physiological systems over the lifespan; and considers the implications of modulating the rate of aging and longevity. The book also includes end-of-chapter discussion questions to help students assess their knowledge of the material. Roger McDonald received his Ph.D. from the University of Southern California and is Professor Emeritus in the Department of Nutrition at the University of California, Davis. Dr. McDonald’s research focused on mechanisms of cellular aging and the interaction between nutrition and aging. His research addressed two key topics in the field: the relationship between dietary restriction and lifespan, and the effect of aging on circadian rhythms and hypothalamic regulation. You can contact Dr. McDonald at [email protected]. Related Titles Ahmad, S. I., ed. Aging: Exploring a Complex Phenomenon (ISBN 978-1-1381-9697-1) Moody, H. R. & J. Sasser. Gerontology: The Basics (ISBN 978-1-1387-7582-4) Timiras, P. S. Physiological Basis of Aging and Geriatrics (ISBN 978-0-8493-7305-3)
Biological Aging Measurement
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Author : Ward Dean
language : en
Publisher:
Release Date : 1988
Biological Aging Measurement written by Ward Dean and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Aging categories.
Aging And Health A Systems Biology Perspective
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Author : A.I. Yashin
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2014-10-14
Aging And Health A Systems Biology Perspective written by A.I. Yashin and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-14 with Medical categories.
Aging is a major risk factor for chronic diseases, which in turn can provide information about the aging of a biological system. This publication serves as an introduction to systems biology and its application to biological aging. Key pathways and processes that impinge on aging are reviewed, and how they contribute to health and disease during aging is discussed. The evolution of this situation is analyzed, and the consequences for the study of genetic effects on aging are presented. Epigenetic programming of aging, as a continuation of development, creates an interface between the genome and the environment. New research into the gut microbiome describes how this interface may operate in practice with marked consequences for a variety of disorders. This analysis is bolstered by a view of the aging organism as a whole, with conclusions about the mechanisms underlying resilience of the organism to change, and is expanded with a discussion of circadian rhythms in aging. Finally, the book presents an outlook for the development of interventions to delay or to reverse the features of aging. The publication is recommended to students, researchers as well as professionals dealing with public health and public policy related to an aging society.
Handbook Of The Biology Of Aging
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Author : Edward L. Schneider
language : en
Publisher: Academic Press
Release Date : 2013-10-22
Handbook Of The Biology Of Aging written by Edward L. Schneider and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.
Handbook of The Biology of Aging, Third Edition provides a general overview to a wide scientific audience of some of the most important topics in biomedical gerontology. The book discusses methodologies for biological aging studies and on animal models. Protein modifications with aging, special senses, circadian rhythms, and the adrenocortical axis are tacked in the book as well. Gerontologists, psychologists, health care professionals, and graduate students will find the book useful.
Biomarkers Of Human Aging
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Author : Alexey Moskalev
language : en
Publisher: Springer Nature
Release Date : 2019-09-13
Biomarkers Of Human Aging written by Alexey Moskalev and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-13 with Science categories.
This book collects and reviews, for the first time, a wide range of advances in the area of human aging biomarkers. This accumulated data allows researchers to assess the rate of aging processes in various organs and systems, and to individually monitor the effectiveness of therapies intended to slow aging. In an introductory chapter, the editor defines biomarkers of aging as molecular, cellular and physiological parameters that demonstrate reproducible changes - quantitative or qualitative - with age. The introduction recounts a study which aimed to create a universal model of biological age, whose most predictive parameters were albumin and alkaline phosphatase (indication liver function), glucose (metabolic syndrome), erythrocytes (respiratory function) and urea (renal function). The book goes on to describe DNA methylation, known as the “epigenetic clock,” as currently the most comprehensive predictor of total mortality. It is also useful for predicting mortality from cancer and cardiovascular diseases, and for analyzing the effects of lifestyle factors including diet, exercise, and education. Individual contributions draw additional insight from research on genetics and epigenetic aging markers, and immunosenescence and inflammaging markers. A concluding chapter outlines the challenge of integrating of biological and clinical markers of aging. Biomarkers of Human Aging is written for professionals and practitioners engaged in the study of aging, and will be useful to both advanced students and researchers.