Biological Amplification Systems In Immunology
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Biological Amplification Systems In Immunology
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Author : N. Day
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Biological Amplification Systems In Immunology written by N. Day and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
Interest in complement developed at the end of the nineteenth century from observations on cellular and humoral defense mechanisms against bacteria. It was recognized at that time that there were factors in body fluids of animals and man that were capable of killing and lysing bacteria in the absence of cellular factors. Due to the efforts of two of the founders of immunology, Bordet and Ehrlich, and their colleagues, by 1912 the multicomponent nature of complement action was well recognized, the sequence of reaction of the components in the lysis of erythrocytes was defined, complement fixation as a major tool for studying antibody-antigen interaction was well established, and studies on the physicochemical properties of the components had been started. Yet, with a few notable exceptions, research on complement was largely abandoned by most "mainstream" immunologists for the following two or three decades. When one looks at the contents of the present volume, it is hard to imagine that as recently as 20 years ago, there were probably fewer than ten major laboratories where complement research was the primary theme. The contents attest to the fact that there are today dozens of laboratories on three continents where research on complement is pursued in depth. It is not easy to point to all the advances that have occurred in complement research during the past few years.
Single Cell Sequencing And Systems Immunology
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Author : Xiangdong Wang
language : en
Publisher: Springer
Release Date : 2015-03-27
Single Cell Sequencing And Systems Immunology written by Xiangdong Wang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-27 with Medical categories.
The volume focuses on the genomics, proteomics, metabolomics, and bioinformatics of a single cell, especially lymphocytes and on understanding the molecular mechanisms of systems immunology. Based on the author’s personal experience, it provides revealing insights into the potential applications, significance, workflow, comparison, future perspectives and challenges of single-cell sequencing for identifying and developing disease-specific biomarkers in order to understand the biological function, activation and dysfunction of single cells and lymphocytes and to explore their functional roles and responses to therapies. It also provides detailed information on individual subgroups of lymphocytes, including cell characters, function, surface markers, receptor function, intracellular signals and pathways, production of inflammatory mediators, nuclear receptors and factors, omics, sequencing, disease-specific biomarkers, bioinformatics, networks and dynamic networks, their role in disease and future prospects. Dr. Xiangdong Wang is a Professor of Medicine, Director of Shanghai Institute of Clinical Bioinformatics, Director of Fudan University Center for Clinical Bioinformatics, Director of the Biomedical Research Center of Zhongshan Hospital, Deputy Director of Shanghai Respiratory Research Institute, Shanghai, China.
Elisa And Other Solid Phase Immunoassays
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Author : D. M. Kemeny
language : en
Publisher: John Wiley & Sons
Release Date : 1991-01-08
Elisa And Other Solid Phase Immunoassays written by D. M. Kemeny and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-01-08 with Science categories.
This is a quick-reference manual on practical aspects of immunoassay. Providing a theoretical and practical basis for modern applications of solid-phase immunoassays, this text brings together experts who have used ELISA and other assays in a variety of fields. Contributors offer step-by-step guidance on how to use the various techniques involved in immunoassay. These techniques are extemely useful to laboratory-based researchers and technicians working on the detection of allergy, the AIDS virus, autoimmunity, etc. Chapters analyze the solid-phase supports used, the amplification systems, and the quantitation and affinity of antibodies and discuss the applications of assays to biology, immunology, and microbiology.
Phylogenetic Perspectives On The Vertebrate Immune System
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Author : Gregory Becker
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Phylogenetic Perspectives On The Vertebrate Immune System written by Gregory Becker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This book contains the proceedings of the first meeting on invertebrate immunity ever sponsored as a summer research conference by the Federation of American Societies for Experimental Biology (FASEB). The conference was held in Copper Mountain, CO from July 11-16, 1999. It was a an extension of a New York Academy of Sciences meeting entitled "Primordial Immunity: Foundations for the Vertebrate Immune System" held on May 2-5,1993 at the Marine Biological Laboratories in Woods Hole, MA. The proceedings of that meeting were published in The Annals of the New York Academy of Sciences (volume 712). At that meeting all the attendes agreed that this type of conference (a relatively small focused gathering) allowed for participation by investigators at all levels of their careers. We further agreed that we should search for a forum that would allow this meeting to continue. The FASEB Summer Research Conference was an excellent vehicle for this type of meeting. Furthermore, this year's participants decided to continue this meeting as a regularly scheduled FASEB sponsored event. This was a unique conference in the sense that it focused upon mechanisms of development and defense in protostome and deuterostome invertebrates and lower vertebrates. There was a strong emphasis on evolutionary cell biology, phylogenetic inferences and the evolution of recognition and regulatory systems.
Immunogenomics And Human Disease
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Author : Andras Falus
language : en
Publisher: John Wiley & Sons
Release Date : 2006-03-30
Immunogenomics And Human Disease written by Andras Falus and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-30 with Science categories.
This book provides an overview of key conceptual and molecular technologies being deployed in immunogenomics, followed by detailed evaluations of the impact of genomics and systems biology on important areas such as cancer immunology, autoimmunity, allergy and the response to infection.
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
Scientific Directory And Annual Bibliography
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Author : National Institutes of Health (U.S.)
language : en
Publisher:
Release Date : 1977
Scientific Directory And Annual Bibliography written by National Institutes of Health (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with Medical research personnel categories.
Monoclonal Antibodies Against Bacteria
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Author : Alberto Macario
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Monoclonal Antibodies Against Bacteria written by Alberto Macario and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Medical categories.
Monoclonal Antibodies against Bacteria, Volume I explores the generation, characterization, and utilization of monoclonal antibodies against bacteria and on other monoclonal products relevant to antibacterial immune responses. Organized into 12 chapters, this book begins with a discussion on monoclonal antibodies against bacteria, encompassing its scope, research, and directions. It shows that the coordinated use of antisera and panels of monoclonal antibodies is proving useful for classification as a diagnostic tool with prognostic implications in the case of pathogens, or as a preliminary step in taxonomy. Also, monoclonal antibodies hold great potential as instruments in working with bacteria for industrial or biotechnological purposes, including genetic engineering. This book also elucidates the use of monoclonal antibodies of predefined molecular specificity for tracing molecular ""signatures"" left by a given strain in other microorganisms, subcellular structures, and materials from ecologic niches. The possibility of antibacterial and antitoxin therapies with monoclonal antibodies is also addressed. This treatise will be a valuable reference work to anyone working with monoclonal antibodies or getting ready to prepare them against the strain(s) (or bacterial structures) of his/her interest.
Current Catalog
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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date :
Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medicine categories.
First multi-year cumulation covers six years: 1965-70.
Inborn Errors Of Immunity And Phagocytosis
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Author : F. Güttler
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Inborn Errors Of Immunity And Phagocytosis written by F. Güttler and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The rapid growth of immunology has greatly increased our understanding of disease; this growth has also generated a subject which at times appears separated from some of the basic medical sciences. Recent studies in the areas of purine metabolism and of polymorphonuclear neutrophil phago cyte function have, however, linked immunology and clinical medicine with biochemistry. The precise defects of the inborn errors of metabolism have now provided good evidence for the importance of purine metabolism specifically the enzymes adenosine deaminase and nucleoside phosphorylase in lymphocyte function. In view of this and the steady advance of clinical and biochemical investigation of the polymorphonuclear neutrophil phago cyte, it appeared timely to review the inborn errors of immunity and phagocytosis at the fifteenth annual symposium of the Society for the Study of Inborn Errors of Metabolism at Elsinore, Denmark on September II-14th, I~77. The papers presented at that meeting form the basis of this volume which brings together contributions from immunologists, biochemists and clinicians. This interdisciplinary communication should be helpful to those concerned with immune function in their patients or in the laboratory. The book is divided into four sections, One: defects of cell-mediated immunity, Two: enzyme defects and immunodeficiency, Three: disorders of non-specific immunity and Four: screening for immunodeficiency. Section One contains two reviews, one on immunodeficiency from Robert Good's group in New York and another on the genetics of the immune system from Arne Svejgaard of Copenhagen.