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Biological Data Mining In Protein Interaction Networks


Biological Data Mining In Protein Interaction Networks
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Biological Data Mining In Protein Interaction Networks


Biological Data Mining In Protein Interaction Networks
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Author : Li, Xiao-Li
language : en
Publisher: IGI Global
Release Date : 2009-05-31

Biological Data Mining In Protein Interaction Networks written by Li, Xiao-Li and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-31 with Technology & Engineering categories.


"The goal of this book is to disseminate research results and best practices from cross-disciplinary researchers and practitioners interested in, and working on bioinformatics, data mining, and proteomics"--Provided by publisher.



Biological Data Mining And Its Applications In Healthcare


Biological Data Mining And Its Applications In Healthcare
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Author : Xiaoli Li
language : en
Publisher: World Scientific
Release Date : 2013-11-28

Biological Data Mining And Its Applications In Healthcare written by Xiaoli Li and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-28 with Science categories.


Biologists are stepping up their efforts in understanding the biological processes that underlie disease pathways in the clinical contexts. This has resulted in a flood of biological and clinical data from genomic and protein sequences, DNA microarrays, protein interactions, biomedical images, to disease pathways and electronic health records. To exploit these data for discovering new knowledge that can be translated into clinical applications, there are fundamental data analysis difficulties that have to be overcome. Practical issues such as handling noisy and incomplete data, processing compute-intensive tasks, and integrating various data sources, are new challenges faced by biologists in the post-genome era. This book will cover the fundamentals of state-of-the-art data mining techniques which have been designed to handle such challenging data analysis problems, and demonstrate with real applications how biologists and clinical scientists can employ data mining to enable them to make meaningful observations and discoveries from a wide array of heterogeneous data from molecular biology to pharmaceutical and clinical domains.



Data Mining For Systems Biology


Data Mining For Systems Biology
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Author : Hiroshi Mamitsuka
language : en
Publisher: Humana
Release Date : 2019-08-04

Data Mining For Systems Biology written by Hiroshi Mamitsuka and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-04 with Science categories.


This fully updated book collects numerous data mining techniques, reflecting the acceleration and diversity of the development of data-driven approaches to the life sciences. The first half of the volume examines genomics, particularly metagenomics and epigenomics, which promise to deepen our knowledge of genes and genomes, while the second half of the book emphasizes metabolism and the metabolome as well as relevant medicine-oriented subjects. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and expert implementation advice that is useful for getting optimal results. Authoritative and practical, Data Mining for Systems Biology: Methods and Protocols, Second Edition serves as an ideal resource for researchers of biology and relevant fields, such as medical, pharmaceutical, and agricultural sciences, as well as for the scientists and engineers who are working on developing data-driven techniques, such as databases, data sciences, data mining, visualization systems, and machine learning or artificial intelligence that now are central to the paradigm-altering discoveries being made with a higher frequency.



Biological Data Mining


Biological Data Mining
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Author : Jake Y. Chen
language : en
Publisher: CRC Press
Release Date : 2009-09-01

Biological Data Mining written by Jake Y. Chen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-01 with Computers categories.


Like a data-guzzling turbo engine, advanced data mining has been powering post-genome biological studies for two decades. Reflecting this growth, Biological Data Mining presents comprehensive data mining concepts, theories, and applications in current biological and medical research. Each chapter is written by a distinguished team of interdisciplin



Protein Interaction Networks


Protein Interaction Networks
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Author : Aidong Zhang
language : en
Publisher:
Release Date : 2014-05-14

Protein Interaction Networks written by Aidong Zhang and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-14 with Science categories.


The first full survey of statistical, topological, data-mining, and ontology-based methods for analyzing protein-protein interaction networks.



Analysis Of Biological Data A Soft Computing Approach


Analysis Of Biological Data A Soft Computing Approach
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Author : Sanghamitra Bandyopadhyay
language : en
Publisher: World Scientific
Release Date : 2007-09-03

Analysis Of Biological Data A Soft Computing Approach written by Sanghamitra Bandyopadhyay and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-03 with Computers categories.


Bioinformatics, a field devoted to the interpretation and analysis of biological data using computational techniques, has evolved tremendously in recent years due to the explosive growth of biological information generated by the scientific community. Soft computing is a consortium of methodologies that work synergistically and provides, in one form or another, flexible information processing capabilities for handling real-life ambiguous situations. Several research articles dealing with the application of soft computing tools to bioinformatics have been published in the recent past; however, they are scattered in different journals, conference proceedings and technical reports, thus causing inconvenience to readers, students and researchers.This book, unique in its nature, is aimed at providing a treatise in a unified framework, with both theoretical and experimental results, describing the basic principles of soft computing and demonstrating the various ways in which they can be used for analyzing biological data in an efficient manner. Interesting research articles from eminent scientists around the world are brought together in a systematic way such that the reader will be able to understand the issues and challenges in this domain, the existing ways of tackling them, recent trends, and future directions. This book is the first of its kind to bring together two important research areas, soft computing and bioinformatics, in order to demonstrate how the tools and techniques in the former can be used for efficiently solving several problems in the latter.



Analyzing Network Data In Biology And Medicine


Analyzing Network Data In Biology And Medicine
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Author : Nataša Pržulj
language : en
Publisher: Cambridge University Press
Release Date : 2019-03-28

Analyzing Network Data In Biology And Medicine written by Nataša Pržulj and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-28 with Language Arts & Disciplines categories.


Introduces biological concepts and biotechnologies producing the data, graph and network theory, cluster analysis and machine learning, using real-world biological and medical examples.



Encyclopedia Of Bioinformatics And Computational Biology


Encyclopedia Of Bioinformatics And Computational Biology
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Author :
language : en
Publisher: Elsevier
Release Date : 2018-08-21

Encyclopedia Of Bioinformatics And Computational Biology written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-21 with Medical categories.


Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases



Clustering Challenges In Biological Networks


Clustering Challenges In Biological Networks
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Author : Sergiy Butenko
language : en
Publisher: World Scientific
Release Date : 2009

Clustering Challenges In Biological Networks written by Sergiy Butenko and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Science categories.


This text offers introductory knowledge of a wide range of clustering and other quantitative techniques used to solve biological problems.



Analysis And Enumeration


Analysis And Enumeration
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Author : Andrea Marino
language : en
Publisher: Springer
Release Date : 2015-03-23

Analysis And Enumeration written by Andrea Marino and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-23 with Computers categories.


In this work we plan to revise the main techniques for enumeration algorithms and to show four examples of enumeration algorithms that can be applied to efficiently deal with some biological problems modelled by using biological networks: enumerating central and peripheral nodes of a network, enumerating stories, enumerating paths or cycles, and enumerating bubbles. Notice that the corresponding computational problems we define are of more general interest and our results hold in the case of arbitrary graphs. Enumerating all the most and less central vertices in a network according to their eccentricity is an example of an enumeration problem whose solutions are polynomial and can be listed in polynomial time, very often in linear or almost linear time in practice. Enumerating stories, i.e. all maximal directed acyclic subgraphs of a graph G whose sources and targets belong to a predefined subset of the vertices, is on the other hand an example of an enumeration problem with an exponential number of solutions, that can be solved by using a non trivial brute-force approach. Given a metabolic network, each individual story should explain how some interesting metabolites are derived from some others through a chain of reactions, by keeping all alternative pathways between sources and targets. Enumerating cycles or paths in an undirected graph, such as a protein-protein interaction undirected network, is an example of an enumeration problem in which all the solutions can be listed through an optimal algorithm, i.e. the time required to list all the solutions is dominated by the time to read the graph plus the time required to print all of them. By extending this result to directed graphs, it would be possible to deal more efficiently with feedback loops and signed paths analysis in signed or interaction directed graphs, such as gene regulatory networks. Finally, enumerating mouths or bubbles with a source s in a directed graph, that is enumerating all the two vertex-disjoint directed paths between the source s and all the possible targets, is an example of an enumeration problem in which all the solutions can be listed through a linear delay algorithm, meaning that the delay between any two consecutive solutions is linear, by turning the problem into a constrained cycle enumeration problem. Such patterns, in a de Bruijn graph representation of the reads obtained by sequencing, are related to polymorphisms in DNA- or RNA-seq data.