Biological Membranes Structure Biogenesis And Dynamics
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Biological Membranes Structure Biogenesis And Dynamics
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Author : Jos A.F. Op den Kamp
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Biological Membranes Structure Biogenesis And Dynamics written by Jos A.F. Op den Kamp and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
The Advanced Study Institute on "Structure, Biogenesis and Dynamics of Biological Membranes, held in Cargese from June 14-26, 1993, has been dealing with four major topics in membrane biochemistry today: lipid dynamics and lipid-protein interactions, protein translocation and insertion, intracellular traffic aud protein structure and folding. The lecturers discussed these topics starting from several disciplines, including biochemistry, cell biology, genetics, and biophysics. This wayan interdisciplinary and very inte~sting view on biological membrane systems was obtained. At first an extensive overview of -mainly biophysical -techniques which can be used to study dynamic processes in membranes was presented. Sophisticated approaches such as ESR and NMR have been applied succesfully to unravel details of specific lipid-protein interactions. x ray analysis provides detailed structural information of several proteins and the possible implications for protein functions. Information obtained this way is complemented by studies on mechanisms and kinetics of protein folding. The latter information is indispensable when discussing protein translocation and insertion: proces:;es in which folding and unfolding play essential roles. Extensive insight was offered in the complicated machinery of phospholipid biosynthesis. In particular, the application of sophisticated genetic techniques has allowed a better understanding of the mechanisms regulating the synthetic machinery and detailed studies on a variety of mutants, lacking one or more of the essential enzymes, have resulted in the beginning of a bL!:
Biological Membranes Structure Biogenesis And Dynamics
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Author : Jos A.F. Op den Kamp
language : en
Publisher: Springer
Release Date : 1994-04-28
Biological Membranes Structure Biogenesis And Dynamics written by Jos A.F. Op den Kamp and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-04-28 with Science categories.
The Advanced Study Institute on "Structure, Biogenesis and Dynamics of Biological Membranes, held in Cargese from June 14-26, 1993, has been dealing with four major topics in membrane biochemistry today: lipid dynamics and lipid-protein interactions, protein translocation and insertion, intracellular traffic aud protein structure and folding. The lecturers discussed these topics starting from several disciplines, including biochemistry, cell biology, genetics, and biophysics. This wayan interdisciplinary and very inte~sting view on biological membrane systems was obtained. At first an extensive overview of -mainly biophysical -techniques which can be used to study dynamic processes in membranes was presented. Sophisticated approaches such as ESR and NMR have been applied succesfully to unravel details of specific lipid-protein interactions. x ray analysis provides detailed structural information of several proteins and the possible implications for protein functions. Information obtained this way is complemented by studies on mechanisms and kinetics of protein folding. The latter information is indispensable when discussing protein translocation and insertion: proces:;es in which folding and unfolding play essential roles. Extensive insight was offered in the complicated machinery of phospholipid biosynthesis. In particular, the application of sophisticated genetic techniques has allowed a better understanding of the mechanisms regulating the synthetic machinery and detailed studies on a variety of mutants, lacking one or more of the essential enzymes, have resulted in the beginning of a bL!:
Structure Dynamics And Biogenesis Of Biomembranes
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Author : Ryo Sato
language : en
Publisher: Springer
Release Date : 1982-10-31
Structure Dynamics And Biogenesis Of Biomembranes written by Ryo Sato and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982-10-31 with Science categories.
Biomembranes are not only principal constituents of the cell but also a major site of biological activity. Studies on biomembranes are therefore, crucial for furthering our understanding of life processes. A special research project on biomembranes involving more than 100 in vestigators was conducted under a grant from the Ministry of Education, Science and Culture of Japan between 1978 and 1981. This has resulted in marked progress on basic biomedical studies on biomembranes in Japan. This book is a compilation of several major developments made during this project in the field of "Structure, Dynamics, and Biogenesis of Biomembranes. " Developments in other fields constitute the contents of a companion volume, "Transport and Bioenergetics in Biomembranes," edited by Sato and Kagawa. In these two volumes the authors review recent advances which have been primarily made in their own labora tories and include relevant work carried out by other investigators. Eight topics are presented in this volume. Ikegami and coworkers review molecular dynamics in lipid bilayers, reconstituted membranes and biological membranes as studied by nanosecond fluorescence spec troscopy with an emphasis on the wobbling in the cone model. The fol lowing two chapters deal with virus-induced membrane fusions. Ohnishi and Maeda describe an assay method for envelope fusion using spin labeled phospholipids and report several characteristic results obtained by this method including low pH-induced fusion of influenza virus.
Characterization Of Biological Membranes
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Author : Mu-Ping Nieh
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2019-07-22
Characterization Of Biological Membranes written by Mu-Ping Nieh and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-22 with Science categories.
The study of membranes has become of high importance in the fields of biology, pharmaceutical chemistry and medicine, since much of what happens in a cell or in a virus involves biological membranes. The current book is an excellent introduction to the area, which explains how modern analytical methods can be applied to study biological membranes and membrane proteins and the bioprocesses they are involved to.
Dynamics And Biogenesis Of Membranes
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Author : Josef A.F. Op den Kamp
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Dynamics And Biogenesis Of Membranes written by Josef A.F. Op den Kamp and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
Membrane proteins, lipids and their glycosylated derivatives are discussed both with respect to their biosynthesis as well as regarding their mutual interaction and assembly into functional membranes. Topics cover a large variety of systems and cells: investigation on virus membranes as well as pro- and eukaryotic cells are included.
Molecular Dynamics In Biological Membranes
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Author : Milton H.Jr. Saier
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Molecular Dynamics In Biological Membranes written by Milton H.Jr. Saier and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Membrane Biogenesis
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Author : Jos A.F. Op den Kamp
language : en
Publisher: Springer
Release Date : 1988-04-13
Membrane Biogenesis written by Jos A.F. Op den Kamp and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-04-13 with Science categories.
Many individual aspects of the dynamics and assembly of biological membranes have been studied in great detail. Cell biological approaches, advanced genetics, biophysics and biochemistry have greatly contributed to an increase in our knowledge in this field.lt is obvious however, that the three major membrane constituents - lipids, proteins and carbohydrates- are studied, in most cases separately and that a coherent overview of the various aspects of membrane biogenesis is not readily available. The NATO Advanced Study Institute on "New Perspectives in the Dynamics of Assembly of Biomembranes" intended to provide such an overview: it was set up to teach students and specialists the achievements obtained in the various research areas and to try and integrate the numerous aspects of membrane assembly into a coherent framework. The articles in here reflect this. Statting with detailed contributions on phospholipid structure, dynamics, organization and biogenesis, an up to date overview of the basic, lipidic backbone of biomembranes is given. Extensive progress is made in the research on membrane protein biosynthesis. In particular the post- and co-translational modification processes of proteins, the mechanisms of protein translocation and the sorting mechanisms which are necessary to direct proteins to their final, intra - or extracellular destination have been characterized in detail. Modern genetic approaches were indispensable in this research area: gene cloning, hybrid protein construction, site directed mutagenesis and sequencing techniques elucidated many functional aspects of specific nucleic acid and amino acid sequences.
Membrane Dynamics And Domains
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Author : Peter J. Quinn
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Membrane Dynamics And Domains written by Peter J. Quinn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
The fluid-mosaic model of membrane structure formulated by Singer and Nicolson in the early 1970s has proven to be a durable concept in terms of the principles governing the organization of the constituent lipids and proteins. During the past 30 or so years a great deal of information has accumulated on the composition of various cell membranes and how this is related to the dif ferent functions that membranes perform. Nevertheless, the task of explaining particular functions at the molecular level has been hampered by lack of struc tural detail at the atomic level. The reason for this is primarily the difficulty of crystallizing membrane proteins which require strategies that differ from those used to crystallize soluble proteins. The unique exception is bacteriorhodopsin of the purple membrane of Halobacterium halobium which is interpolated into a membrane that is neither fluid nor in a mosaic configuration. To date only 50 or so membrane proteins have been characterised to atomic resolution by diffraction methods, in contrast to the vast data accumulated on soluble proteins. Another factor that has been difficult to explain is the reason why the lipid compliment of membranes is often extremely complex. Many hundreds of different molecular species of lipid can be identified in some membranes. Remarkably, the particular composition of each membrane appears to be main tained within relatively narrow limits and its identity distinguished from other morphologically-distinct membranes.
The Structure Of Biological Membranes Third Edition
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Author : Philip L. Yeagle
language : en
Publisher: CRC Press
Release Date : 2011-07-18
The Structure Of Biological Membranes Third Edition written by Philip L. Yeagle and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-18 with Medical categories.
Biological membranes provide the fundamental structure of cells and viruses. Because much of what happens in a cell or in a virus occurs on, in, or across biological membranes, the study of membranes has rapidly permeated the fields of biology, pharmaceutical chemistry, and materials science. The Structure of Biological Membranes, Third Edition provides readers with an understanding of membrane structure and function that is rooted in the history of the field and brought to the forefront of current knowledge. The first part of the book focuses on the fundamentals of lipid bilayers and membrane proteins. Three introductory chapters supply those new to the field with the tools and conceptual framework with which to approach the state-of-the-art chapters that follow. The second part of the book presents in-depth analyses of focused subjects within the study of membranes, covering topics that include: Phase behavior of lipid bilayers Lipid bilayers as an isolated structure Cholesterol’s role in cell biology Lateral organization of membranes The role of membrane lipids in initial membrane protein folding Membrane protein synthesis and assembly of oligomeric membrane proteins Membrane protein stability with relationships to function and protein turnover Membrane protein function using a transport protein Interactions between membrane proteins and membrane lipids A final chapter pulls together many of the topics, examining in detail the complexity inherent in the synthesis and assembly of lipids and proteins in mitochondrial membranes. With contributions from leading researchers, this completely revised and updated third edition reflects recent advances in the field of biological membranes. It offers a valuable resource for students, as well as structural biologists, biophysicists, cell biologists, biochemists, and researchers in the pharmaceutical and biotechnology industries. What’s New in This Edition: Three accessible chapters introduce students to the field of biological membranes Completely revised and updated chapters present current topics in membrane research
Membrane Organization And Dynamics
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Author : Amitabha Chattopadhyay
language : en
Publisher: Springer
Release Date : 2017-12-06
Membrane Organization And Dynamics written by Amitabha Chattopadhyay and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-06 with Science categories.
This volume brings together information on membrane organization and dynamics from a variety of spectroscopic, microscopic and simulation approaches, spanning a broad range of time scales. The implication of such dynamic information on membrane function in health and disease is a topic of contemporary interest. The chapters cover various aspects of membrane lipid and protein dynamics, explored using a battery of experimental and theoretical approaches. The synthesis of information and knowledge gained by utilizing multiple approaches will provide the reader with a comprehensive understanding of the underlying membrane dynamics and function, which will help to develop robust dynamic models for the understanding of membrane function in healthy and diseased states. In the last few years, crystal structures of an impressive number of membrane proteins have been reported, thanks to tremendous advances in membrane protein crystallization techniques. Some of these recently solved structures belong to the G protein-coupled receptor (GPCR) family, which are particularly difficult to crystallize due to their intrinsic flexibility. Nonetheless, these static structures do not provide the necessary information to understand the function of membrane proteins in the complex membrane milieu. This volume will address the dynamic nature of membrane proteins within the membrane and will provide the reader with an up-to date overview of the theory and practical approaches that can be used. This volume will be invaluable to researchers working in a wide range of scientific areas, from biochemistry and molecular biology to biophysics and protein science. Students of these fields will also find this volume very useful. This book will also be of great use to those who are interested in the dynamic nature of biological processes.