Biological Therapy For Inflammatory Bowel Disease
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Biological Therapy For Inflammatory Bowel Disease
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Author : Raquel Franco Leal
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-03-11
Biological Therapy For Inflammatory Bowel Disease written by Raquel Franco Leal and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-11 with Medical categories.
The treatment of inflammatory bowel disease (IBD) has posed a major challenge since its appearance. Biomedical researchers, physicians, gastroenterologists, and surgeons have struggled to improve the quality of life of their patients and have sought, above all else, to keep the disease under remission for as long as possible. Blockers for tumoral necrosis factor alpha (TNF-alpha) were the first biological drugs to be discovered and for this reason they played a crucial role in the subsequent evolution of IBD treatment. The aim of this book is to provide an overview of such drugs and the latest developments in IBD immunopathology. Our contributors discuss the main indications, efficacy, and possible side effects of the different types of drugs available today for IBD treatment.
Treatment Of Inflammatory Bowel Disease With Biologics
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Author : Adam S. Cheifetz
language : en
Publisher: Springer
Release Date : 2017-11-09
Treatment Of Inflammatory Bowel Disease With Biologics written by Adam S. Cheifetz and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-09 with Medical categories.
This book is a concise yet comprehensive overview of the use of biologics for the treatment of Crohn’s disease and ulcerative colitis. The volume details how best to utilize these medications in order to optimize their efficacy and safety, as well as how to understand, recognize, and treat complications that may arise from using biologics to treat IBD. The text also focuses on new data, novel biologics, and biosimilars of this rapidly expanding field. Written by experts in the field, Treatment of Inflammatory Bowel Disease with Biologics is a valuable resource for gastroenterologists, allied health professionals, fellows, and trainees who treat patients with inflammatory bowel disease.
Biologics In Inflammatory Bowel Disease
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Author : Scott Plevy Associate Professor of Medicine Division of Gastroenterology
language : en
Publisher: Oxford University Press, USA
Release Date : 2010
Biologics In Inflammatory Bowel Disease written by Scott Plevy Associate Professor of Medicine Division of Gastroenterology and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.
SERIES OVERVIEW: The Oxford American Pocket Notes are a series of ultra-concise, small-format books for healthcare professionals on topics related to the diagnosis, treatment and management of various medical conditions. Each title typically features an outline of key points, guidelines and tools such as patient assessments and treatment algorithms, for a specific area of medical diagnosis and/or management. Highly practical in format, content and style, the Pocket Notes serve as a quick, easily accessible point-of-care reference for busy practitioners. In effect, they are miniature versions of the Oxford American Medical Library and Oxford American Handbooks in Medicine, capturing the key essentials needed for appropriate assessment and treatment. Inflammatory bowel disease (IBD) is a gastrointestinal condition which causes inflammation of the lining of the digestive tract. This disease affects an estimated one million Americans, usually in the forms of ulcerative colitis (UC) and Crohn's disease (CD). These two diseases have similar symptoms and are often confused for one another. Crohn's disease can occur anywhere in the digestive tract, often spreading deep into the layers of affected tissues, but ulcerative colitis usually affects only the innermost lining (mucosa) of the large intestine and rectum. IBD patients suffer from severe diarrhea and abdominal pain, and may experience other complications, such as arthritis and kidney stones, that affect the body beyond the intestinal tract. The Oxford American Pocket Notes: Biologics in Inflammatory Bowel Disease is a practical guide to the safe administration of biological agents to treat inflammatory gastrointestinal illnesses. This ultra-concise and practical volume focuses on tumor necrosis factor (TNF) blocking therapy (TNF blocker), an important new class of biologic therapy indicated for the treatment of several rheumatic and other auto-immune disorders, including Crohn's disease and ulcerative colitis. This uniquely compact and affordable book features evidence-based discussion and guidelines on the mechanism of action, dosing, administration and safety considerations for the biologic agents approved to treat CD and UC, thus providing practicing physicians with easily accessible tools and insights on the use of these drugs in a daily practice setting. Culled from the pages of Handbook of Biological Therapy, this portable guide is a valuable resource for gastroenterologists, primary care physicians and other healthcare providers involved in the management of these chronic but treatable diseases.
Biologics In Inflammatory Bowel Disease An Issue Of Gastroenterology Clinics Of North America
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Author : Edward V. Loftus, Jr
language : en
Publisher: Elsevier Health Sciences
Release Date : 2014-08-21
Biologics In Inflammatory Bowel Disease An Issue Of Gastroenterology Clinics Of North America written by Edward V. Loftus, Jr and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-21 with Medical categories.
By the time this issue of Gastroenterology Clinics of North America is released, it will have been 16 years since infliximab was approved by the US Food and Drug Administration for the treatment of moderate to severe Crohn disease. Not only have we come a long way in understanding the efficacy and safety of infliximab, we are beginning to understand how and when to use the drug. Furthermore, as of this writing, we have five other biologic agents approved for either Crohn disease or ulcerative colitis, and there are many more molecules currently in drug development for these indications. In this issue,the Editors have assembled a collection of experts to provide the most cutting-edge information on the status of biologic therapy for inflammatory bowel disease.
Biological Therapy For Inflammatory Bowel Diseases
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Author : Daniel C. Baumgart
language : en
Publisher:
Release Date : 2010
Biological Therapy For Inflammatory Bowel Diseases written by Daniel C. Baumgart and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with categories.
Biologic Therapy For Inflammatory Bowel Diseases
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Author : Daniel C. Baumgart
language : en
Publisher:
Release Date : 2010
Biologic Therapy For Inflammatory Bowel Diseases written by Daniel C. Baumgart and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Electronic books categories.
Advanced Therapy Of Inflammatory Bowel Disease Volume 2
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Author : Theodore M. Bayless
language : en
Publisher: PMPH-USA
Release Date : 2014-05-14
Advanced Therapy Of Inflammatory Bowel Disease Volume 2 written by Theodore M. Bayless and has been published by PMPH-USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-14 with Crohn's disease categories.
Now published in two volumes to accommodate new chapters on the many advances in understanding and treatment options, this set of volumes represents the definitive reference on inflammatory bowel disease, a spectrum of diseases that is receiving increasing attention as our understanding of the etiological factors increases and diagnostic tools are refined. Basic research accelerated at the beginning of this decade and is now yielding new, more targeted treatments than were available just a few years ago. Volume 1 is on IBD and Ulcerative Colitis, and Volume 2 is on IBD and Crohn's Disease. All areas that were covered in the 2nd edition have been expanded and updated. New sections include the rapidly expanding knowledge of genetics and the role of the intestinal flora and environmental factors in etiology and pathogenesis. Among the 168 chapters, there are 20 on biologic therapies and 30 on surgical management. The consultant/authors clearly state their approach to important issues, such as the duration of immunomodulator and of anti-TNF-a use and the options for managing isolated low-grade dysplasia. A strong focus on the individual patient is woven throughout both volumes, including the benefits and risks of potentially life-altering therapies and surgeries. Entire sections detail concerns about the well-being of each person. This book provides information for health professionals who help both pediatric and adult patients navigate through the lifelong shadow of a chronic, probably genetically determined ordeal.
New Frontiers In Therapeutic Drug Monitoring Of Biologics In Inflammatory Bowel Disease And Other Immune Mediated Inflammatory Diseases
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Author : Konstantinos Papamichael
language : en
Publisher: Mdpi AG
Release Date : 2023-12-26
New Frontiers In Therapeutic Drug Monitoring Of Biologics In Inflammatory Bowel Disease And Other Immune Mediated Inflammatory Diseases written by Konstantinos Papamichael and has been published by Mdpi AG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-26 with Medical categories.
Therapeutic drug monitoring (TDM) has emerged as a useful tool for optimizing biological treatment in patients with inflammatory bowel disease (IBD) and other immune-mediated inflammatory diseases (IMID). Reactive TDM has rationalized the management of primary non-response and secondary loss of response to biologics, while cumulative evidence suggests that proactive TDM is efficacious for optimizing anti-tumour necrosis factor (anti-TNF) therapy in patients with IBD. Proactive TDM can be very useful for optimizing biological therapy in specific IBD populations, such as pregnant women as well as patients with perianal fistulizing Crohn's disease and acute severe ulcerative colitis who are characterized by high drug clearance. Preliminary data suggest that proactive TDM may also have a role in de-escalating anti-TNF therapy in patients in clinical remission including stopping the immunomodulator when combined with anti-TNF therapy. However, several knowledge gaps and limitations hinder the wide implementation of TDM in clinical practice, including the optimal drug concentration to target the lag time between sampling and results and the lack of harmonization of TDM assays. Recent advances regarding the role of TDM include the use of rapid point-of-care assays and the incorporation of model-informed precision dosing. The aim of this Special Issue is to highlight the clinical utility of TDM and discuss the barriers and recent advances of TDM of biologics in IBD and other IMID.
Biologics In Inflammatory Bowel Disease
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Author : Scott Plevy
language : en
Publisher: OUP USA
Release Date : 2012-10
Biologics In Inflammatory Bowel Disease written by Scott Plevy and has been published by OUP USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10 with Medical categories.
Biologics in Inflammatory Bowel Disease is a practical guide to the safe administration of biological agents to treat inflammatory gastrointestinal illnesses. This ultraconcise and practical volume focuses on tumour necrosis factor (TNF) blocking therapy (TNF blocker), and important new class of biologic therapy indicated for the treatment of several rheumatic and other auto-immune disorders, including Crohn's disease and ulcerative colitis.
Anti Tumor Necrosis Factor Therapy In Inflammatory Bowel Disease
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Author : G. Rogler
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2015-07-09
Anti Tumor Necrosis Factor Therapy In Inflammatory Bowel Disease written by G. Rogler and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-09 with Medical categories.
The introduction of anti-tumour necrosis factor (TNF) antibodies into the treatment of patients with IBD about fifteen years ago has dramatically improved the quality of life for patients with severe Crohn's disease and ulcerative colitis. But despite the fact this therapeutic approach has been around for quite some time, there has been no comprehensive overview to date. The book at hand aims to amend this shortcoming, presenting for the first time a thorough overview on TNF action, mechanisms of anti-TNF therapy, treatment strategies, side effects, monitoring, biosimilars and related issues. Including state-of-the-art information and research results, this publication will be a valuable source of information and guide clinicians to the optimal treatment decision, improving the quality of life of patients with inflammatory bowel disease. Moreover, rheumatologists or even dermatologists might also find this book of interest.