Biology And Management Of Unusual Plasma Cell Dyscrasias
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Biology And Management Of Unusual Plasma Cell Dyscrasias
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Author : Todd M. Zimmerman
language : en
Publisher: Springer
Release Date : 2016-09-17
Biology And Management Of Unusual Plasma Cell Dyscrasias written by Todd M. Zimmerman and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-17 with Medical categories.
This unique book focuses on the non-myeloma plasma cell dyscrasias. A key resource for this group of diseases, the book features the latest in emerging knowledge and therapeutic developments, including novel therapies. Each disease-specific chapter discusses biology, disease course, and appropriate therapeutic interventions, covering plasma cell leukemia, plasmacytoma, POEMS Syndrome and Castleman's Disease, Waldenström macroglobulinemia, immunoglobin deposition disease, and cryoglobulinemic syndromes, among others. The only book dedicated to this intriguing family of diseases, Biology and Management of Unusual Plasma Cell Dyscrasias will be a long-lasting reference for clinicians and scientists alike.
Plasma Cell Dyscrasias
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Author : Aldo M. Roccaro
language : en
Publisher: Springer
Release Date : 2016-10-01
Plasma Cell Dyscrasias written by Aldo M. Roccaro and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-01 with Medical categories.
This book provides a concise overview of the state of the art in the biology and treatment of plasma cell malignancies, a heterogeneous group of diseases primarily characterized by the presence of clonal plasma cells within the bone marrow or extramedullary sites. The plasma cell dyscrasias investigated include monoclonal gammopathy of undetermined significance (MGUS), multiple myeloma, plasmacytoma, immunoglobulin deposition diseases (primary amyloidosis and systemic light and heavy chain deposition diseases), and Waldenström’s macroglobulinemia. In the case of multiple myeloma, the coverage ranges from genomic aberrations and microRNAs to treatment for different patient groups, upcoming novel therapies, immunotherapy, and transplantation. The book reflects the significant research advances achieved in this field during the past few years, which have enhanced our understanding of the molecular mechanisms responsible for the pathogenesis of plasma cell dyscrasias.
Multiple Myeloma
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Author : Morie A. Gertz
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-10-01
Multiple Myeloma written by Morie A. Gertz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-01 with Medical categories.
This is a comprehensive, state-of-the-art guide to the diagnosis, treatment, and biology of multiple myeloma and related plasma disorders. Edited and written by a multidisciplinary group of recognized authorities from the Mayo Clinic, it presents clear guidelines on diagnosis and therapy and covers all aspects of multiple myeloma, from molecular classification and diagnosis, to risk stratification and therapy. Closely related plasma cell disorders such as solitary plasmacytoma, Waldenstrom macroglobulinemia, and light chain amyloidosis are discussed in detail as well. The book addresses often overlooked topics, including the role of radiation therapy, vertebral augmentation, and supportive care. Our understanding of this group of disorders is developing at an unprecedented rate, and Multiple Myeloma meets the need among oncologists and hematologists for a clear, timely, and authoritative resource on their biology, diagnosis, and treatment.
Periodic And Non Periodic Fevers
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Author : Rolando Cimaz
language : en
Publisher: Springer Nature
Release Date : 2019-10-29
Periodic And Non Periodic Fevers written by Rolando Cimaz and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-29 with Medical categories.
This book, written by very well-known opinion leaders in the field, covers all aspects of periodic and non –periodic fevers, and related disorders. The expression refers to several different auto-inflammatory diseases, showing similar symptoms–the primary symptom being a recurrent fever for an infectious cause cannot be found. The opening chapters give some historical hints, explain the genetic basis of the disease and provide insights into the pathogenesis derived from recent experimental studies and guides the reader through classification and nomenclature. A large part of the book is then devoted to a detailed description of the specific related diseases and their clinical presentations, the disease course, and potential complications in both pediatric and adult patients. The advice regarding treatment is based on the best currently available evidence in this constantly evolving area. The book is part of Springer’s series Rare Diseases of the Immune System, which presents recently acquired knowledge on pathogenesis, diagnosis, and therapy with the aim of promoting a more holistic approach to these conditions. Autoinflammatory diseases are hereditary disorders that are caused by single-gene defects in innate immune regulatory pathways and are characterized by a clinical and biological inflammatory syndrome in which there is limited, if any, evidence of autoimmunity. Periodic and Non-Periodic Fevers will be an invaluable source of up-to-date information for all practitioners involved in the care of patients with these disease.
Castleman Disease An Issue Of Hematology Oncology Clinics E Book
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Author : Frits van Rhee
language : en
Publisher: Elsevier Health Sciences
Release Date : 2017-11-30
Castleman Disease An Issue Of Hematology Oncology Clinics E Book written by Frits van Rhee and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-30 with Medical categories.
This issue of Hematology/Oncology Clinics, edited by Dr. Frits van Rhee and Dr. Nikhil C. Munshi, focuses on Castleman Disease. Topics include, but are not limited to, Epidemiology; Pathogenesis; Role of Interleukin 6 in Castleman Disease; Pathology, Diagnosis; Unicentric Castleman Disease; Treatment of HHV8 related Multicentric Castleman Disease; Treatment of HHV8 negative Castleman Disease; TAFRO Syndrome; POEMS; and more.
Allogeneic Stem Cell Transplantation
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Author : Hillard M. Lazarus
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-03-02
Allogeneic Stem Cell Transplantation written by Hillard M. Lazarus and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-02 with Medical categories.
Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.
Diagnostic Pathology Of Hematopoietic Disorders Of Spleen And Liver
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Author : Ling Zhang
language : en
Publisher: Springer Nature
Release Date : 2020-04-29
Diagnostic Pathology Of Hematopoietic Disorders Of Spleen And Liver written by Ling Zhang and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-29 with Medical categories.
This book provides a comprehensive and up-to-date overview of the pathologic features of common benign and malignant hematopoietic disorders in spleen and liver for practicing pathologists, hematopathologists and clinicians. The authors are from large academic centers, affiliated teaching hospitals and central referral clinics and are experienced in the diagnosis of hematopoietic disorders in the spleen and liver. The book consists of 21 chapters, with the first three chapters devoted to normal histologic features, conventional, cytogenetic and molecular studies necessary for the diagnosis of hematopoietic disorders in the spleen and liver. Chapters 4 to 17 cover the primary and secondary mature B- and T/NK cell lymphomas, Hodgkin lymphoma, B and T cell lymphoblastic leukemias, myeloid neoplasms, histiocytic and dendritic neoplasms, and post-transplant disorders including post transplant lymphoproliferative disorders. Chapters 19 to 21 encompass red blood cell disorders, other benign hematologic disorders and infectious/inflammatory disorders that could mimic hematopoietic neoplasms. These chapters are formatted on specific hematopoietic neoplasms to comprise epidemiology, etiology, pathogenesis, morphology, immunophenotyping, molecular genetics, prognosis and brief treatment guidelines. Diagnostic caveats are included in order to have a quick review of the key points in each chapter. Diagnostic Pathology of Hematopoietic Disorders of Spleen and Liver covers most, if not all of the benign and malignant hematopoietic disorders in the spleen and liver and serves as a practical and useful resource for general pathologists and hematopathologists.
American Society Of Hematology Self Assessment Program
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Author : Timothy Graubert
language : en
Publisher:
Release Date : 2013-06-04
American Society Of Hematology Self Assessment Program written by Timothy Graubert and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-04 with Hematology categories.
Hematologists and others working in hematology-related fields need to stay current with the latest advances in the rapidly evolving disciplines of adult and pediatric hematology. The American Society of Hematology Self-Assessment Program (ASH-SAP) is the only complete, comprehensive, educational resource available that fulfills this need, while also providing thorough board and recertification preparation, as well as AMA PRA Category 1 Credit'.
Cancer And The Kidney
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Author : Eric P. Cohen
language : en
Publisher: Oxford University Press, USA
Release Date : 2010-11-11
Cancer And The Kidney written by Eric P. Cohen and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-11 with Medical categories.
Cancer and the Kidney covers the challenging overlap area of nephrology and oncology, both in terms of kidney problems in cancer patients, and cancer that affects kidney patients, including assessment of kidney function, to paraneoplastic disorders, acquired cysts and native kidney cancers, and all points inbetween.
Multiple Myeloma And Other Plasma Cell Neoplasms
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Author : Meletios A. Dimopoulos
language : en
Publisher: Springer
Release Date : 2018-02-16
Multiple Myeloma And Other Plasma Cell Neoplasms written by Meletios A. Dimopoulos and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-16 with Medical categories.
This book is a comprehensive source of up-to-date information on plasma cell neoplasms. Key features include the provision of new criteria for the diagnosis of symptomatic multiple myeloma requiring treatment and the description of novel therapies for myeloma and other plasma cell neoplasms that have only very recently been licensed by the U.S. Food and Drug Administration. Examples include lenalidomide as first-line therapy, panobinostat in combination with bortezomib plus dexamethasone for relapsed/refractory myeloma, ibrutinib for Waldenström’s macroglobulinemia, and new therapeutic regimens for systemic amyloidosis and POEMS syndrome. Information is also provided on drug combinations that have shown encouraging results and are very near to approval. Other important aspects covered in the book are the role of different imaging modalities in workup and the significance of newly acquired data relating to prognosis and minimal residual disease. Readers will find Multiple Myeloma and Other Plasma Cell Neoplasms to be a rich source of knowledge that will be invaluable in improving patient management.