Biology Computing And The History Of Molecular Sequencing
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Biology Computing And The History Of Molecular Sequencing
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Author : M. García-Sancho
language : en
Publisher: Springer
Release Date : 2012-05-11
Biology Computing And The History Of Molecular Sequencing written by M. García-Sancho and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-11 with Science categories.
Sequencing is often associated with the Human Genome Project and celebrated achievements concerning the DNA molecule. However, the history of this practice comprises not only academic biology, but also the world of computer-assisted information management. The book uncovers this history, qualifying the hype and expectations around genomics.
Biology Computing And The History Of Molecular Sequencing
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Author : M. García-Sancho
language : en
Publisher: Palgrave Macmillan
Release Date : 2012-05-11
Biology Computing And The History Of Molecular Sequencing written by M. García-Sancho and has been published by Palgrave Macmillan this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-11 with Science categories.
Sequencing is often associated with the Human Genome Project and celebrated achievements concerning the DNA molecule. However, the history of this practice comprises not only academic biology, but also the world of computer-assisted information management. The book uncovers this history, qualifying the hype and expectations around genomics.
A History Of Molecular Biology
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Author : Michel Morange
language : en
Publisher: Harvard University Press
Release Date : 2000
A History Of Molecular Biology written by Michel Morange and has been published by Harvard University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with History categories.
Every day it seems the media focus on yet another new development in biology--gene therapy, the human genome project, the creation of new varieties of animals and plants through genetic engineering. These possibilities have all emanated from molecular biology. A History of Molecular Biology is a complete but compact account for a general readership of the history of this revolution. Michel Morange, himself a molecular biologist, takes us from the turn-of-the-century convergence of molecular biology's two progenitors, genetics and biochemistry, to the perfection of gene splicing and cloning techniques in the 1980s. Drawing on the important work of American, English, and French historians of science, Morange describes the major discoveries--the double helix, messenger RNA, oncogenes, DNA polymerase--but also explains how and why these breakthroughs took place. The book is enlivened by mini-biographies of the founders of molecular biology: Delbrück, Watson and Crick, Monod and Jacob, Nirenberg. This ambitious history covers the story of the transformation of biology over the last one hundred years; the transformation of disciplines: biochemistry, genetics, embryology, and evolutionary biology; and, finally, the emergence of the biotechnology industry. An important contribution to the history of science, A History of Molecular Biology will also be valued by general readers for its clear explanations of the theory and practice of molecular biology today. Molecular biologists themselves will find Morange's historical perspective critical to an understanding of what is at stake in current biological research.
The Local Configuration Of New Research Fields
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Author : Martina Merz
language : en
Publisher: Springer
Release Date : 2015-10-27
The Local Configuration Of New Research Fields written by Martina Merz and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-27 with Social Science categories.
This new Yearbook addresses the question of how policy, place, and organization are made to matter for a new research field to emerge. Bringing together leading historians, sociologists, and organizational researchers on science and technology, the volume answers this question by offering in-depth case studies and comparative perspectives on multiple research fields in their nascent stage, including molecular biology and materials science, nanotechnology, and synthetic biology. The Yearbook brings to bear the lessons of constructivist ethnography and the “practice turn” in Science and Technology Studies (STS) more broadly on the qualitative, comparative, and critical inquiry of new research fields. In doing so, it offers unprecedented insights into the complex interplay of national research policies, regional clusters, particular research institutions, and novel research practices in and for any emerging field of (techno-)science. It systematically investigates national and regional differences, including the variable mobilization of such differences, and probes them for organizational topicality and policy relevance.
Collecting Experiments
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Author : Bruno J. Strasser
language : en
Publisher: University of Chicago Press
Release Date : 2019-06-07
Collecting Experiments written by Bruno J. Strasser and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-07 with Technology & Engineering categories.
Databases have revolutionized nearly every aspect of our lives. Information of all sorts is being collected on a massive scale, from Google to Facebook and well beyond. But as the amount of information in databases explodes, we are forced to reassess our ideas about what knowledge is, how it is produced, to whom it belongs, and who can be credited for producing it. Every scientist working today draws on databases to produce scientific knowledge. Databases have become more common than microscopes, voltmeters, and test tubes, and the increasing amount of data has led to major changes in research practices and profound reflections on the proper professional roles of data producers, collectors, curators, and analysts. Collecting Experiments traces the development and use of data collections, especially in the experimental life sciences, from the early twentieth century to the present. It shows that the current revolution is best understood as the coming together of two older ways of knowing—collecting and experimenting, the museum and the laboratory. Ultimately, Bruno J. Strasser argues that by serving as knowledge repositories, as well as indispensable tools for producing new knowledge, these databases function as digital museums for the twenty-first century.
Postgenomics
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Author : Sarah S. Richardson
language : en
Publisher: Duke University Press
Release Date : 2015-05-29
Postgenomics written by Sarah S. Richardson and has been published by Duke University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-29 with Science categories.
Ten years after the Human Genome Project’s completion the life sciences stand in a moment of uncertainty, transition, and contestation. The postgenomic era has seen rapid shifts in research methodology, funding, scientific labor, and disciplinary structures. Postgenomics is transforming our understanding of disease and health, our environment, and the categories of race, class, and gender. At the same time, the gene retains its centrality and power in biological and popular discourse. The contributors to Postgenomics analyze these ruptures and continuities and place them in historical, social, and political context. Postgenomics, they argue, forces a rethinking of the genome itself, and opens new territory for conversations between the social sciences, humanities, and life sciences. Contributors. Russ Altman, Rachel A. Ankeny, Catherine Bliss, John Dupré, Michael Fortun, Evelyn Fox Keller, Sabina Leonelli, Adrian Mackenzie, Margot Moinester, Aaron Panofsky, Sarah S. Richardson, Sara Shostak, Hallam Stevens
Data Centric Biology
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Author : Sabina Leonelli
language : en
Publisher: University of Chicago Press
Release Date : 2016-11-18
Data Centric Biology written by Sabina Leonelli and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-18 with Philosophy categories.
Over the last two decades, digital access to data has revolutionized research methods and ways of doing science in the biological and biomedical fields. Prominent scientists have characterized this shift as leading to a new, data-intensive paradigm for research, encompassing innovative ways to produce, store, disseminate, and interpret huge masses of data. In this book Sabina Leonelli explores the epistemological challenges this poses to how life is researched and understood. By following how data travels across research contexts, and the role played by standards, theories, models, and human agency in shaping their evidential value, she shows the conditions under which digitally available data further our understanding of life. Turning to how the characteristics of data-intensive science bear on philosophical debates, Leonelli explores the shifting criteria for what counts as scientific evidence and how data are transformed into new knowledge. In short, she argues that a philosophical characterization of how data and knowledge move from one context to another is of fundamental importance to a productive philosophical understanding of contemporary scientific practices."
The Gene
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Author : Hans-Jörg Rheinberger
language : en
Publisher: University of Chicago Press
Release Date : 2018-01-26
The Gene written by Hans-Jörg Rheinberger and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-26 with Science categories.
Few concepts played a more important role in twentieth-century life sciences than that of the gene. Yet at this moment, the field of genetics is undergoing radical conceptual transformation, and some scientists are questioning the very usefulness of the concept of the gene, arguing instead for more systemic perspectives. The time could not be better, therefore, for Hans-Jörg Rheinberger and Staffan Müller-Wille's magisterial history of the concept of the gene. Though the gene has long been the central organizing theme of biology, both conceptually and as an object of study, Rheinberger and Müller-Wille conclude that we have never even had a universally accepted, stable definition of it. Rather, the concept has been in continual flux—a state that, they contend, is typical of historically important and productive scientific concepts. It is that very openness to change and manipulation, the authors argue, that made it so useful: its very mutability enabled it to be useful while the technologies and approaches used to study and theorize about it changed dramatically.
Milieus Of Minutiae
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Author : Elizabeth Brogden
language : en
Publisher: University of Virginia Press
Release Date : 2024-12-19
Milieus Of Minutiae written by Elizabeth Brogden and has been published by University of Virginia Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-19 with Literary Criticism categories.
The long history of tiny matter(s) in the sciences, thought, and culture From catastrophic weather and steady warming caused by the accumulation of carbon particles in the Earth’s atmosphere to societies brought to a standstill by microscopic viruses, the new millennium has reminded us of how the minutest of phenomena can have outsized effects. This notion is one that has preoccupied the European and Anglo-American cultural imaginary since at least early modernity. Milieus of Minutiae brings together an interdisciplinary group of scholars to investigate various forms and appearances of minutiae prior to and beyond the advent of magnification. The collection illuminates connections between the empirical practices and technologies with which minutiae have come to be associated and the broader, more diffuse discourses—from the philosophical to the artistic—that have attended theories of smallness before and after Hooke’s Micrographia. Placing essays on Renaissance poetry, Romantic fiction, and matters of punctuation alongside essays on early modern germ theory and the optics of microscopic technology, this rigorously framed volume extends from sixteenth-century pathology to twentieth-century architectural theory, natural science to literature and art.
Life S Greatest Secret
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Author : Matthew Cobb
language : en
Publisher: Profile Books
Release Date : 2015-06-11
Life S Greatest Secret written by Matthew Cobb and has been published by Profile Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-11 with History categories.
Life's Greatest Secret is the story of the discovery and cracking of the genetic code. This great scientific breakthrough has had far-reaching consequences for how we understand ourselves and our place in the natural world. The code forms the most striking proof of Darwin's hypothesis that all organisms are related, holds tremendous promise for improving human well-being, and has transformed the way we think about life. Matthew Cobb interweaves science, biography and anecdote in a book that mixes remarkable insights, theoretical dead-ends and ingenious experiments with the pace of a thriller. He describes cooperation and competition among some of the twentieth century's most outstanding and eccentric minds, moves between biology, physics and chemistry, and shows the part played by computing and cybernetics. The story spans the globe, from Cambridge MA to Cambridge UK, New York to Paris, London to Moscow. It is both thrilling science and a fascinating story about how science is done.