Biomarker Discovery In The Developing World Dissecting The Pipeline For Meeting The Challenges
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Biomarker Discovery In The Developing World Dissecting The Pipeline For Meeting The Challenges
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Author : Sanjeeva Srivastava
language : en
Publisher: Springer
Release Date : 2016-09-30
Biomarker Discovery In The Developing World Dissecting The Pipeline For Meeting The Challenges written by Sanjeeva Srivastava and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-30 with Medical categories.
This book is oriented towards post-graduates and researchers with interest in proteomics and its applications in clinical biomarker discovery pipeline. Biomarker discovery has long been the research focus of many life scientists globally. However, the pipeline starting from discovery to validation to regulation as a diagnostic or therapeutic molecule follows a complex trajectory. This book aims to provide an in-depth synopsis on each of these developmental phases attendant to biomarker “life cycle” with emphasis on the emerging and significant role of proteomics. The book begins with a perspective on the role of biorepositories and need for biobanking practices in the developing world. The next chapter focuses on disease heterogeneity in context to geographical bias towards susceptibility to the disease and the role of multi-omics techniques to devise disruptive innovations towards biomarker discovery. Chapter 3 focuses on various omics-based platforms that are currently being used for biomarker discovery, their principles and workflow. Mass spectrometry is emerging as a powerful technology for discovery based studies and targeted validation. Chapter 4 aims at providing a glimpse of the basic workflow and considerations in mass spectrometry based studies. Rapid and aptly targeted research funding has often been deemed as one of the decisive factors enabling excellent science and path breaking innovations. With the need for sophistication required in multi-omics research, Chapter 5 focuses on innovative funding strategies such as crowdfunding and Angel philanthropy. Chapter 6 provides the latest advances in education innovation, the premise and reality of bioeconomy especially in a specific context of the developing world, not to mention the new concept of “social innovation” to link biomarkers with socially responsible and sustainable applications. Chapter 7, in ways similar to biomarkers, discusses the biosimilars as a field that has received much focus and prominence recently due to their immense potential in clinical and pharmaceutical innovation literatures. The broader goal post-biomarker discovery is to translate their use in clinics. However, the road from bench-to-bed side is arduous and complex that is subject to oversight from various national and international regulatory bodies. Chapter 8 underscores these regulatory science considerations and provides a concise overview on intellectual property rights in biomarker discovery. Thus, this book contributed by eminent biomarker scientists, clinicians, translational researchers and social scientists holistically covers the various facets of the biomarker discovery journey from “cell to society” in developing world. The lessons learned and highlighted here are of interest to the life sciences community in a global and interdependent world.
Agricultural Bioeconomy
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Author : Chetan Keswani
language : en
Publisher: Academic Press
Release Date : 2022-11-29
Agricultural Bioeconomy written by Chetan Keswani and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-29 with Technology & Engineering categories.
Agricultural Bioeconomy: Innovation and Foresight in the Post-COVID Era presents recent advancements in biotechnology, exploring the optimal utilization of technologies to provide rapid and impactful economic recovery and sustainable resources in a future that will bear the mark of COVID-19. Understanding that there is a necessary balance between risk and reward, this book provides a foundational hypothesis as well as operational direction for addressing the commercialization and regulatory issues in a bio-based economy where agricultural output is at the core. By presenting adaptable practices to successfully establish and progress agri-based global bioeconomies, the book features a new paradigm focused on technological foresight and response to future risks and disasters. Key considerations include assessing and managing the urban bioeconomy, climate change mitigation, biofuels and bioenergy, GMOs, and employment generation. This book provides the solid next step toward future-proofing global economies using a combination of agricultural technologies and economic goals. Professionals and advanced students focused on the production of renewable biological resources and their conversion into value-added products including food, feed, bio-based products, and bioenergy will find this book useful. - Addresses recent issues emerging in agro-based economies - Empowers utilization of biotechnology to address worldwide ecological issues - Presents adaptable, risk-management approaches to the adoption of socially and financially valuable agri-based technologies
Artificial Intelligence In Healthcare
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Author : Adam Bohr
language : en
Publisher: Academic Press
Release Date : 2020-06-21
Artificial Intelligence In Healthcare written by Adam Bohr and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-21 with Computers categories.
Artificial Intelligence (AI) in Healthcare is more than a comprehensive introduction to artificial intelligence as a tool in the generation and analysis of healthcare data. The book is split into two sections where the first section describes the current healthcare challenges and the rise of AI in this arena. The ten following chapters are written by specialists in each area, covering the whole healthcare ecosystem. First, the AI applications in drug design and drug development are presented followed by its applications in the field of cancer diagnostics, treatment and medical imaging. Subsequently, the application of AI in medical devices and surgery are covered as well as remote patient monitoring. Finally, the book dives into the topics of security, privacy, information sharing, health insurances and legal aspects of AI in healthcare. - Highlights different data techniques in healthcare data analysis, including machine learning and data mining - Illustrates different applications and challenges across the design, implementation and management of intelligent systems and healthcare data networks - Includes applications and case studies across all areas of AI in healthcare data
Reducing The Impact Of Dementia In America
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Author : National Academies of Sciences Engineering and Medicine
language : en
Publisher:
Release Date : 2022-04-26
Reducing The Impact Of Dementia In America written by National Academies of Sciences Engineering and Medicine and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-26 with categories.
As the largest generation in U.S. history - the population born in the two decades immediately following World War II - enters the age of risk for cognitive impairment, growing numbers of people will experience dementia (including Alzheimer's disease and related dementias). By one estimate, nearly 14 million people in the United States will be living with dementia by 2060. Like other hardships, the experience of living with dementia can bring unexpected moments of intimacy, growth, and compassion, but these diseases also affect people's capacity to work and carry out other activities and alter their relationships with loved ones, friends, and coworkers. Those who live with and care for individuals experiencing these diseases face challenges that include physical and emotional stress, difficult changes and losses in their relationships with life partners, loss of income, and interrupted connections to other activities and friends. From a societal perspective, these diseases place substantial demands on communities and on the institutions and government entities that support people living with dementia and their families, including the health care system, the providers of direct care, and others. Nevertheless, research in the social and behavioral sciences points to possibilities for preventing or slowing the development of dementia and for substantially reducing its social and economic impacts. At the request of the National Institute on Aging of the U.S. Department of Health and Human Services, Reducing the Impact of Dementia in America assesses the contributions of research in the social and behavioral sciences and identifies a research agenda for the coming decade. This report offers a blueprint for the next decade of behavioral and social science research to reduce the negative impact of dementia for America's diverse population. Reducing the Impact of Dementia in America calls for research that addresses the causes and solutions for disparities in both developing dementia and receiving adequate treatment and support. It calls for research that sets goals meaningful not just for scientists but for people living with dementia and those who support them as well. By 2030, an estimated 8.5 million Americans will have Alzheimer's disease and many more will have other forms of dementia. Through identifying priorities social and behavioral science research and recommending ways in which they can be pursued in a coordinated fashion, Reducing the Impact of Dementia in America will help produce research that improves the lives of all those affected by dementia.
The Truth In Small Doses
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Author : Clifton Leaf
language : en
Publisher: Simon and Schuster
Release Date : 2013-07-16
The Truth In Small Doses written by Clifton Leaf and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07-16 with History categories.
A decade ago Leaf, a cancer survivor himself, began to investigate why we had made such limited progress fighting this terrifying disease. The result is a gripping narrative that reveals why the public's immense investment in research has been badly misspent, why scientists seldom collaborate and share their data, why new drugs are so expensive yet routinely fail, and why our best hope for progress-- brilliant young scientists-- are now abandoning the search for a cure.
Sustainability Of Rice In The Global Food System
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Author : Noreen G. Dowling
language : en
Publisher: Int. Rice Res. Inst.
Release Date : 1998
Sustainability Of Rice In The Global Food System written by Noreen G. Dowling and has been published by Int. Rice Res. Inst. this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Technology & Engineering categories.
Book Of Abstracts Of The 71st Annual Meeting Of The European Federation Of Animal Science
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Author : Scientific Committee
language : en
Publisher: Brill Wageningen Academic
Release Date : 2020-11-21
Book Of Abstracts Of The 71st Annual Meeting Of The European Federation Of Animal Science written by Scientific Committee and has been published by Brill Wageningen Academic this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-21 with categories.
This Book of Abstracts is the main publication of the 71st Annual Meeting of the European Federation of Animal Science (EAAP). It contains abstracts of the invited papers and contributed presentations of the sessions of EAAP's eleven Commissions: Animal Genetics, Animal Nutrition, Animal Management and Health, Animal Physiology, Cattle Production, Sheep and Goat Production, Pig Production, Horse Production and Livestock Farming Systems, Insects and Precision Livestock Farming.
Cancer Biomarkers
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2007-03-27
Cancer Biomarkers written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-27 with Medical categories.
Many cancer patients are diagnosed at a stage in which the cancer is too far advanced to be cured, and most cancer treatments are effective in only a minority of patients undergoing therapy. Thus, there is tremendous opportunity to improve the outcome for people with cancer by enhancing detection and treatment approaches. Biomarkers will be instrumental in making that transition. Advances in biotechnology and genomics have given scientists new hope that biomarkers can be used to improve cancer screening and detection, to improve the drug development process, and to enhance the effectiveness and safety of cancer care by allowing physicians to tailor treatment for individual patients—an approach known as personalized medicine. However, progress overall has been slow, despite considerable effort and investment, and there are still many challenges and obstacles to overcome before this paradigm shift in oncology can become a reality.