Biomarkers In Genitourinary Cancers Volume I


Biomarkers In Genitourinary Cancers Volume I
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Biomarkers In Genitourinary Cancers Volume I


Biomarkers In Genitourinary Cancers Volume I
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Author : Eric A. Singer
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-25

Biomarkers In Genitourinary Cancers Volume I written by Eric A. Singer and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-25 with Medical categories.




Biomarkers In Genitourinary Cancers Volume Ii


Biomarkers In Genitourinary Cancers Volume Ii
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Author : Riccardo Tellini
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-14

Biomarkers In Genitourinary Cancers Volume Ii written by Riccardo Tellini and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-14 with Medical categories.




Genitourinary Cancers


Genitourinary Cancers
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Author : Siamak Daneshmand
language : en
Publisher: Springer
Release Date : 2018-08-31

Genitourinary Cancers written by Siamak Daneshmand and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-31 with Medical categories.


This book addresses the most pressing current questions in the management of urologic malignancies. The rapid advances in imaging and molecular markers are placed into a clinical context, with explanation of their effects on prognosis and treatment planning. Similarly, progress in immunotherapy is carefully examined, focusing in particular on the role of immune checkpoint inhibitors in both early- and late-stage urologic malignancies. Looking beyond the improvements in minimally invasive techniques for urologic cancers, the impacts of care coordination pathways and enhanced recovery after surgery protocols are reviewed. Readers will also find enlightening discussion of the decision algorithm for the treatment of early-stage, high-grade bladder cancer, taking into account evidence on the most advanced treatment options and the circumstances in which surgery may need to be expedited. The penultimate chapter discusses the Cancer Genome Atlas project for bladder cancer, and the book closes by considering contemporary medical and surgical management of testicular cancer.



Biomarkers And Immunotherapy For Genitourinary Tumors


Biomarkers And Immunotherapy For Genitourinary Tumors
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Author : Hui Dai
language : en
Publisher: Frontiers Media SA
Release Date : 2024-04-02

Biomarkers And Immunotherapy For Genitourinary Tumors written by Hui Dai and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-02 with Medical categories.


Genitourinary tumors consist of a large variety of malignancies located in the urinary and the reproductive systems, mainly including prostate cancer, bladder cancer, and renal tumors. Apart from surgeries, various systemic treatments have been used for the whole-course management of genitourinary tumors, including radiation therapy, chemotherapy, and hormonal therapy. However, the characteristics of progression, metastasis, and drug resistance deriving from tumors require and breed novel treatments. Furthermore, exploring biomarkers of genitourinary tumors at the early stage is also beneficial to strengthen the management of patients with tumors. Additionally, the diagnostic and prognostic value of the potential biomarkers for immunotherapy and combined therapy of genitourinary tumors are underexplored. On the basis of precision treatments, the advent of immune-based therapies, including immune checkpoint inhibitors (ICIs, antibodies targeting PD-L1 /PD-1 and CTLA-4 pathways), tumor vaccines, and other therapies, has extended the scope of treatment modalities. FDA has until now approved the clinical application of immune checkpoint inhibitors in a wide range of diseases including some types of genitourinary tumors, whereas not all patients with genitourinary tumors are suitable for immune-based therapies, therefore, the understanding of its underlying mechanism is key to develop effective treatments based on current ICI-based immunotherapy.



Emerging Biomarkers In Personalized Therapy Of Urologic Tumors


Emerging Biomarkers In Personalized Therapy Of Urologic Tumors
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Author : Rodolfo Montironi
language : en
Publisher: Frontiers Media SA
Release Date : 2019-07-31

Emerging Biomarkers In Personalized Therapy Of Urologic Tumors written by Rodolfo Montironi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-31 with categories.


The identification of effective biomarkers has becoming a major focus in cancer research, mainly due to the necessity of selecting potentially responsive patients in order to improve their outcomes, as well as to reduce the toxicity and costs related to ineffective treatments. In genitourinary tumors, the lack of biomarkers does not allow for the development of personalized strategies for a single patient, thus representing a major goal in this field. This eBook includes the description of these emerging techniques and identify the most promising biomarkers in genitourinary tumors.



Prostate And Other Genitourinary Cancers


Prostate And Other Genitourinary Cancers
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Author : Vincent T. DeVita
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2016-03-18

Prostate And Other Genitourinary Cancers written by Vincent T. DeVita and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-18 with Medical categories.


Selected from the world’s leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient. Prostate and Other Genitourinary Cancers: Cancer: Principles & Practice of Oncology, 10th Edition, offers a comprehensive and balanced view of this rapidly changing field, meeting the needs of oncology practitioners, fellows, and others who need an in-depth understanding of prostate and GU cancer. The print reference gives you the solid, dependable guidance you’ve come to expect from this outstanding title, and the Inkling version features new quarterly updates written by a team of experts selected by the authors.



Neoadjuvant Immunotherapy Treatment Of Localized Genitourinary Cancers


Neoadjuvant Immunotherapy Treatment Of Localized Genitourinary Cancers
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Author : Andrea Necchi
language : en
Publisher: Springer Nature
Release Date : 2022-01-03

Neoadjuvant Immunotherapy Treatment Of Localized Genitourinary Cancers written by Andrea Necchi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-03 with Medical categories.


This book aims to provide readers with a current overview of enrolling trials with immune-checkpoint inhibitors in the preoperative setting of localized bladder cancer, renal cell carcinoma, and prostate cancer. The advent of immunotherapy has revolutionized treatments of genitourinary malignancy and evolved strategies for multidisciplinary management. This book explains neoadjuvant checkpoint inhibitors in localized genitourinary cancers, providing insights into the mechanisms of response and development of resistance of cancer cells to immunotherapy. It debates optimal trial design of preoperative checkpoint inhibitors in GU tumors, including optimal endpoints and the role of pathologic response as a surrogate endpoint of survival. It also illuminates clinical management of patients with organ-confined GU tumors, such as side effect management and perioperative safety, before providing an overview of biomarker use for patient selection across the early-stage GU malignancies. Lastly, the book provides the reader with the most up-to-date data emerging from clinical trials involving immunotherapy in early-stage GU malignancies. Neoadjuvant Immunotherapy Treatment of Localized Genitourinary Cancers: Multidisciplinary Management provides a comprehensive review of the field, serving as a valuable resource for urologists, medical oncologists, pathologists, fellows in urologic oncology, upper-level residents training in urology and medical oncology, as well as pharmacists interested in RCC clinicians.



Genitourinary Cancer 1


Genitourinary Cancer 1
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Author : D.F. Paulson
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Genitourinary Cancer 1 written by D.F. Paulson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Malignant disease of the genitourinary tract continues to provide a major health hazard. The study of these disease processes has been hampered at the clinical level as there has been a serious lack of reasonably controlled treatment trials, and at the basic science level as many of the animal model systems do not compare favorably with the human tumor situation. This volume defines current cancer treatment and research and its appli cation to the control of human genitourinary malignancy. The authors have developed their chapters in such a way as to provide an up-to-date resource for the clinician who is involved in day-to-day patient care problems, for the clinician-investigator who is attempting to construct programs designed to evaluate the impact of current treatments, and for the clinician-scientist who is seeking to apply basic research technology and skills to understand ing and control in this disease area. This book does not attempt to cover the entire breadth of urinary malig nant disease, but focuses in depth on specific problem areas. It provides the reader with sufficient background and understanding for him to be able to evaluate future studies in the areas addressed, or even to develop his own projects. A reasonable balance has been established between clinical and basic research problems, recognizing that the two disciplines truly are not separable. The book serves to define the state of the art and, as such, will of urologic oncology.



Cancer


Cancer
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Author : Gary S. Stein
language : en
Publisher: John Wiley & Sons
Release Date : 2019-09-18

Cancer written by Gary S. Stein and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-18 with Science categories.


A guide to recent insights into the genetic and epigenetic parameters of cancer biology and pathology and emerging clinical applications The thoroughly updated second edition of The Biology and Treatment of Cancer, now titled Cancer: Prevention, Early Detection, Treatment and Recovery, goes beyond reviewing the fundamental properties of cancer biology and the relevant issues associated with treatment of the disease. The new edition contains coverage of additional "patient centric" topics and presents cancer biology with selection of topics, facts, and perspectives written in easy-to-understand terms. With contributions from noted experts, the book explores recent advances in the understanding of cancer including breakthroughs in the molecular and cellular basis of cancer and provides strategies for approaching cancer prevention, early detection, and treatment. The authors incorporate recent information on the genetic and epigenetic parameters of cancer biology and pathology with indications of emerging clinical applications. The text offers a unique guide to cancer prevention, early detection, treatment, and recovery for students, caregivers, and most importantly cancer patients. This significant book: Incorporates current insight into the genetic and epigenetic parameters of cancer biology and pathology and information on emerging clinical applications Contains contributions from leaders in cancer research, care, and clinical trials Offers an accessible guide to an accurate and balanced understanding of cancer and the cancer patient Focuses on the importance of cancer prevention, early detection, treatment, and survivorship Written for medical students, students of cancer biology, and caregivers and cancer patients, Cancer: Prevention, Early Detection, Treatment and Recovery offers an authoritative overview of the challenges and opportunities associated with cancer biology, cancer research, and the spectrum of clinical considerations.



Immunological Implications And Molecular Diagnostics Of Genitourinary Cancer


Immunological Implications And Molecular Diagnostics Of Genitourinary Cancer
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Author : Moulay Mustapha Ennaji
language : en
Publisher: Academic Press
Release Date : 2022-10-07

Immunological Implications And Molecular Diagnostics Of Genitourinary Cancer written by Moulay Mustapha Ennaji and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-07 with Medical categories.


Immunological Implications and Molecular Diagnostics of Genitourinary Cancer updates on recent accomplishments, unifying concepts, and future challenges in the study of tumor-associated immune cells, emphasizing genitourinary cancers. The presence of inflammatory immune cells in human tumors raise a fundamental question: How do cancer cells avoid destruction by immune attack? In principle, tumor development can be controlled by cytotoxic innate and adaptive immune cells, however, as tumors develop from neoplastic tissue to clinically detectable tumors, cancer cells evolve different mechanisms. This book covers research on the immunological implications of genitourinary cancer with a comprehensive view, especially surrounding diagnosis and cellular mechanisms. Discusses the impact of the immune system on the initiation, progression and treatment of cancer Provides insights on the important role of the suppressor genes and oncogenes in genitourinary cancers Shows the advantages of combining clinical issues of urologic cancers with immunological techniques, like immunohistochemistry and immunofluorescence Demonstrates the implications genitourinary cancer has on the human innate immune system