Biomarkers Of Neuroinflammation


Biomarkers Of Neuroinflammation
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Biomarkers Of Neuroinflammation


Biomarkers Of Neuroinflammation
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2018-03-16

Biomarkers Of Neuroinflammation written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-16 with Medical categories.


Neuroinflammation is a burgeoning area of interest in academia and biopharma, with a broadly acknowledged role in many central nervous system (CNS) disorders. However, there is little agreement on the pathophysiological mechanisms that underlie the manifestations of neuroinflammation in the CNS compartment and how neuroinflammation operates as a driver and also as a consequence of disease in the brain. Moreover, another unclear area is how to translate increased understanding of the mechanisms that underlie neuroinflammation and its manifestations in the CNS to therapeutics. To address these gaps in understanding mechanisms and how to translate that understanding into therapeutics, the Forum on Neuroscience and Nervous System Disorders of the National Academies of Sciences, Engineering, and Medicine convened a workshop on March 20-21, 2017, bringing together key leaders in the field from industry, academia, and governmental agencies to explore the role and mechanisms of neuroinflammation in a variety of CNS diseases. The workshop also considered strategies to advance the identification and validation of biomarkers of neuroinflammation that could accelerate development of therapies, bringing much-needed treatments to patients with disorders ranging from neuroinflammatory diseases such as multiple sclerosis (MS) to neuropsychiatric disorders such as depression. This publication summarizes the presentations and discussions from the workshop.



Biomarkers In Neurology


Biomarkers In Neurology
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Author : Mohamed Mosaad Salama
language : en
Publisher: Frontiers Media SA
Release Date : 2020-05-12

Biomarkers In Neurology written by Mohamed Mosaad Salama and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-12 with categories.




Resolution Of Inflammation Mechanisms Mediators Biomarkers


Resolution Of Inflammation Mechanisms Mediators Biomarkers
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Author : Paola Patrignani
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-01

Resolution Of Inflammation Mechanisms Mediators Biomarkers written by Paola Patrignani and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-01 with Science categories.




Neurodegenerative Diseases Biomarkers


Neurodegenerative Diseases Biomarkers
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Author : Philip V. Peplow
language : en
Publisher: Humana
Release Date : 2022-10-16

Neurodegenerative Diseases Biomarkers written by Philip V. Peplow and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-16 with Medical categories.


This volume presents recent data on the latest achievements in new and emerging technologies for biomarkers and for innovations in their assessment. The chapters cover topics such as activation of microglia and macrophages in neurodegenerative diseases; oxidative stress and cellular dysfunction in neurodegenerative diseases; TSPO PET imaging as a biomarker of neuroinflammation in neurodegenerative disorders; and imaging biomarkers in Huntington's disease and amyotrophic lateral sclerosis. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and comprehensive, Neurodegenerative Diseases Biomarkers: Towards Translating Research to Clinical Practice is a valuable resource for both experimental and clinical experts in the field of neurodegenerative diseases who are looking to expand their knowledge of novel biomarkers in different types of neurodegenerative diseases.



Neuroinflammation And Cognition


Neuroinflammation And Cognition
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Author : Ashok Kumar
language : en
Publisher: Frontiers Media SA
Release Date : 2019-03-22

Neuroinflammation And Cognition written by Ashok Kumar and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-22 with categories.


Aging is one of the major risk factors for the onset and progression of various neurodegenerative diseases. Neuroinflammation is a common feature of virtually every central nervous system disease, and is acknowledged as a likely mediator of cognitive impairments. Systemic inflammation levels are augmented with advanced age and neurodegeneration. The influence of age on neuroinflammatory responses including glial activation, increased production of proinflammatory cytokines, and aberrant neuronal signaling could magnify the deterioration of the central nervous system microenvironment in disease, and may contribute to enhanced cognitive impairment. This eBook is a collection of highly informative original research articles, providing comprehensive aspect of neuroinflammation and possible therapeutic interventions in rescuing cognitive impairments.



Biomarkers Of Brain Injury And Neurological Disorders


Biomarkers Of Brain Injury And Neurological Disorders
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Author : Kevin K. W. Wang
language : en
Publisher: CRC Press
Release Date : 2014-10-28

Biomarkers Of Brain Injury And Neurological Disorders written by Kevin K. W. Wang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-28 with Medical categories.


This book explores the recent advances in the techniques and platforms used in biomarker research that have revolutionized the way we study, diagnose, and treat brain injury conditions. The contributors describe different biomarker studies pertaining to brain injury and other neurological disorders and analyze the different models and technologies used to identify these biological markers. The book includes findings from "Omics research" that have been utilized to decipher and identify such biomarkers. It discusses protein, microRNA, and altered gene profiles and reviews neurological disorders such as multiple sclerosis, Charcot-Marie-Tooth disease, and prion and Alzheimer’s disease.



Neuroinflammation In Vascular Dementia


Neuroinflammation In Vascular Dementia
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Author : Gary Rosenberg
language : en
Publisher: Academic Press
Release Date : 2022-09-07

Neuroinflammation In Vascular Dementia written by Gary Rosenberg and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-07 with Medical categories.


Neuroinflammation in Vascular Dementia describes the molecular mechanisms that drive this transition to mixed pathology, along with the newer lifestyle and pharmacological approaches that can reduce the incidence of dementia. The book describes the practical aspects of neuroimaging methods, along with novel neuroimaging methods, using MRI, that are becoming important clinically. The author also discusses how the diagnosis of dementias will be greatly aided by biomarkers from neuroimaging, blood and CSF biochemistry and neuropsychological testing in the future. This information will be used in precision medicine to design treatment strategies based on the most likely causes of the disease. Dementia research has undergone dramatic growth driven by current and projected increases in the aging of the population, and thus leading to a larger number of patients with dementia by 2050. Hence, advances in neuroimaging, brain chemistry, and genetics have accelerated our understanding of diseases that lead to cognitive decline. Reviews the clinical aspects and subtypes of dementia Explains molecular pathways involved in brain inflammation Includes the role of CSF and blood in diagnosis Covers established and novel neuroimaging methods Discusses established and developing treatment strategies Identifies future directions, such as machine learning and precision medicine



Trends In Biomarkers For Neurodegenerative Diseases Current Research And Future Perspectives


Trends In Biomarkers For Neurodegenerative Diseases Current Research And Future Perspectives
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Author : Suman Dutta
language : en
Publisher: Frontiers Media SA
Release Date : 2023-03-23

Trends In Biomarkers For Neurodegenerative Diseases Current Research And Future Perspectives written by Suman Dutta and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-23 with Science categories.




Neuroinflammation


Neuroinflammation
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Author : Alireza Minagar
language : en
Publisher: Elsevier
Release Date : 2010-12-17

Neuroinflammation written by Alireza Minagar and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-17 with Science categories.


Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, and brain trauma as well as meningitis and contributes to the generation of pain. We are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage through tolerance to modulation and repair. This book discusses some of the more common neuro-inflammatory diseases. Topics covered include multiple sclerosis, optic neuritis and Susac syndrome. Comprehensive review of the latest developments in neuroinflammation Includes contributions from leading authorities



Biomarkers For Traumatic Brain Injury


Biomarkers For Traumatic Brain Injury
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Author : Svetlana Dambinova
language : en
Publisher: Royal Society of Chemistry
Release Date : 2012

Biomarkers For Traumatic Brain Injury written by Svetlana Dambinova and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.


Due to injuries sustained in sports and in combat, interest in traumatic brain injury (TBI) has never been greater. This book will fulfill a gap in understanding of what is occurring in the brain following injury that can subsequently be detected in biological fluids and imaging.