[PDF] Biomarkers To Enable Therapeutics Development In Neurodevelopmental Disorders - eBooks Review

Biomarkers To Enable Therapeutics Development In Neurodevelopmental Disorders


Biomarkers To Enable Therapeutics Development In Neurodevelopmental Disorders
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Biomarkers To Enable Therapeutics Development In Neurodevelopmental Disorders


Biomarkers To Enable Therapeutics Development In Neurodevelopmental Disorders
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Author : Mustafa Sahin
language : en
Publisher: Frontiers Media SA
Release Date : 2020-12-31

Biomarkers To Enable Therapeutics Development In Neurodevelopmental Disorders written by Mustafa Sahin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-31 with Science categories.


This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.



Capute And Accardo S Neurodevelopmental Disabilities In Infancy And Childhood


Capute And Accardo S Neurodevelopmental Disabilities In Infancy And Childhood
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Author : Fatima Y Ismail
language : en
Publisher: Elsevier
Release Date : 2024-11-26

Capute And Accardo S Neurodevelopmental Disabilities In Infancy And Childhood written by Fatima Y Ismail and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-26 with Medical categories.


Capute and Accardo's Neurodevelopmental Disabilities in Infancy and Childhood, Fourth Edition provides updated foundational, theoretical, and practical knowledge on the spectrum and continuum of neurodevelopmental disabilities shaped by ongoing advances in neuroscience and related disciplines. It reviews the over-arching principles of assessment, diagnosis, and management of patients with a wide range of neurodevelopmental disabilities. Streamlined or fully rewritten chapters, including developmental screening and surveillance, neuroimaging and genetic evaluation, early intervention, principles of pharmacological treatment, principles of successful management programs, aging and transition planning, telemedicine and care in low-resource settings are included.The book's practical, expert-led approach aims to prepare future clinicians to skillfully assess and manage children with neurodevelopmental disabilities with the aid of clinical approach flowcharts to common presentations, diagnostic algorithms and clinic notes templates. - Provides the most comprehensive, authoritative, and up-to-date single volume on practical aspects of care for patients with neurodevelopmental disabilities - Presents a reorganized single volume that is more accessible than previous editions - Features new chapters on telemedicine, novel therapies, care in low resource settings, and the future of neurodevelopmental disabilities - Includes full color illustrations throughout, along with explanatory figures - Covers clinical approaches and diagnostic algorithms and templates for clinic notes that are available for online download



Exploring And Exploiting Genetic Risk For Psychiatric Disorders


Exploring And Exploiting Genetic Risk For Psychiatric Disorders
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Author : Joshua A. Gordon
language : en
Publisher: MIT Press
Release Date : 2023-10-10

Exploring And Exploiting Genetic Risk For Psychiatric Disorders written by Joshua A. Gordon and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-10 with Medical categories.


An edited volume that looks at the state of psychiatric genetics and how to chart a path forward. In this edited collection, experts from psychiatric and statistical genetics, neurobiology, and clinical psychiatry investigate whether and how to pursue the discovery of additional genetic risk factors for mental illnesses. Using the existing knowledge and frameworks of genetic risk factors, they look at how a better understanding of the biology that underlies mental illnesses can improve and enhance the care that patients receive.



Cognitive And Communication Interventions


Cognitive And Communication Interventions
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Author : Martha S. Burns
language : en
Publisher: Plural Publishing
Release Date : 2020-10-12

Cognitive And Communication Interventions written by Martha S. Burns and has been published by Plural Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-12 with Medical categories.


Understanding the recent science about how therapy changes the brain can empower clinicians to face the challenges of increasingly demanding medical and educational settings. However, many speech-language pathologists (SLPs) are unaware of the vast impact new neuroscience research has on clinical practice. Cognitive and Communication Interventions: Neuroscience Applications for Speech-Language Pathologists is a practical guide that informs and enables SLP’s, clinical psychologists, and other therapeutic professionals to use new research to enhance their clinical outcomes. Although based on independent neuroscience principles and research, this unique book is designed to be a readable and scientifically sound clinical guidebook. Written with the busy clinician in mind, this professional resource uses accessible, easy-to-understand language to walk readers through the complexities of neuroscience and provide workable strategies for application. The beginning chapters break down important concepts, such as neuroplasticity, environmental stressors, and connectomics, to create a base of understanding. The middle chapters delve into recent investigations of factors that potentially affect typical brain development, as well as disrupt connectomics. The final chapters provide neuroscience considerations for intervention, including the “What, How, and When” of therapy and other important considerations for individualizing and maximizing outcomes. Throughout the book, clinicians will also find case studies that provide examples of the practical applications of neuroscience research and study questions to improve memory and inference.



Psychological Support By Cognitive Behavioral Therapy For Sickle Cell Disease


Psychological Support By Cognitive Behavioral Therapy For Sickle Cell Disease
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Author : Edenilson Brandl
language : en
Publisher: Edenilson Brandl
Release Date :

Psychological Support By Cognitive Behavioral Therapy For Sickle Cell Disease written by Edenilson Brandl and has been published by Edenilson Brandl this book supported file pdf, txt, epub, kindle and other format this book has been release on with Psychology categories.


Sickle Cell Disease (SCD) is a complex and multifaceted condition, not only in terms of its physical symptoms but also in the psychological and emotional toll it can take on those affected. Throughout my career and experiences with individuals navigating this illness, I have come to understand the profound impact that mental health has on managing chronic disease. This book, Psychological Support by Cognitive Behavioral Therapy for Sickle Cell Disease, is born from the desire to bridge the gap between medical treatment and psychological support for individuals living with SCD. Cognitive Behavioral Therapy (CBT) has long been recognized as an effective tool in managing psychological distress, particularly in chronic illness settings. By addressing the thoughts, feelings, and behaviors that arise from the experience of illness, CBT helps individuals reclaim a sense of control and empowerment in their daily lives. For those with Sickle Cell Disease, who often experience unpredictable episodes of pain, fatigue, and other physical symptoms, having a reliable psychological framework for managing these challenges is crucial. This book is designed to provide a comprehensive, accessible guide for individuals, caregivers, and mental health professionals. We explore the biological basis of SCD, alongside the genetic and hereditary aspects, to provide a solid understanding of the disease. But we also go beyond biology—delving into how trauma, mental health, and cognitive processes influence the overall experience of SCD. The tools of CBT are presented in a structured way, offering readers practical techniques to manage both the psychological and physical burdens of the disease. Additionally, we delve into various cognitive behavioral strategies that can be tailored to each individual’s needs, whether through personalized therapeutic approaches, pain management, or navigating the complexities of living with a genetic illness. The book also addresses specific challenges such as societal pressures, navigating medical bureaucracy, and the emotional impact on family dynamics. Ultimately, this book aims to provide hope and resilience, not only through scientific knowledge but also through practical strategies that foster mental and emotional strength. My hope is that, through the tools and approaches outlined here, individuals with Sickle Cell Disease will find support in their journey toward well-being.



New Developments In Redox Biology


New Developments In Redox Biology
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Author : Asim K. Duttaroy
language : en
Publisher: Academic Press
Release Date : 2025-09-01

New Developments In Redox Biology written by Asim K. Duttaroy and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-09-01 with Science categories.


New Developments in Redox Biology: Fundamental Roles in Health and Disease offers a comprehensive exploration of the influence of the redox system and the complex relationships between oxidative stress, biological development, health and disease. Divided into three sections, it explores the role of the redox system across developmental biology, non-communicable diseases, and infectious diseases. The first section includes chapters exploring oxygen availability in embryonic development, the influence of stress factors and intra-cellular signalling during embryogenesis, and how stem cells maintain homeostasis under oxidative stress. Section two considers topics such as the origin of cancer stem cells related to hypoxia, redox-related biomarkers in tumorigenesis and metabolic disorders, and the role of oxidation and reduction systems in autoimmune disorders and neurodegeneration. The final section focuses on redox regulation in infectious illness and includes chapters on redox biomarkers in host-pathogen interaction, the role of redox control in zoonotic diseases, and the significance of hypoxia on the ability of microbial pathogens to invade the gut. Antiviral drugs and the use of redox regulation in their mechanism of action is also explored. New Developments in Redox Biology: Fundamental Roles in Health and Disease offers a multidisciplinary approach to the topic, providing valuable insights to those seeking to expand their expertise in redox biology and its implications for human health and disease. In particular, researchers and advanced students working across molecular biology, cell biology, biochemistry, developmental biology and related fields will find this book useful. - Explores the fundamental role of redox biology in developmental processes and cellular homeostasis - Investigates the impact of oxidative stress on non-communicable diseases, including cancer, metabolic, and autoimmune disorders - Examines redox regulation in infectious diseases and host-pathogen interactions - Provides detailed insights into redox-related biomarkers and their diagnostic and therapeutic potential - Equips readers with cutting-edge knowledge on redox biology through multi-omics approaches



Enabling Technology For Neurodevelopmental Disorders


Enabling Technology For Neurodevelopmental Disorders
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Author : Tanu Wadhera
language : en
Publisher: Routledge
Release Date : 2022-04-20

Enabling Technology For Neurodevelopmental Disorders written by Tanu Wadhera and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-20 with Medical categories.


This cutting-edge volume explores how technological tools can be designed, engineered and implemented to assess and support individuals with neurodevelopmental disorders from diagnosis through to rehabilitation. Tanu Wadhera and Deepti Kakkar and their expert contributors focus on technological tools as equalizers in Neurodevelopmental disorders (NDDs) at every stage, the importance of demand-specific design, and how we can best engineer and deploy both invasive and non-invasive individual-centered approaches that support and connect individuals. Considering the perspectives of patients, clinicians and technologists, it explores key topics including design and evaluation of platforms for tech-tools, automated diagnosis, brain imaging techniques, tech-diagnostic frameworks with AI and machine learning, sensing technology, smart brain prosthetics, gamification, alternative communication devices, and education tools and interactive toys. Outlining future challenges for research, Enabling Technology for Neurodevelopmental Disorders is useful for scholars and professionals in psychology, technology, engineering and medicine concerned with design, development and evaluation of a range of assistive technological tools.



Psychological Support By Cognitive Behavioral Therapy For Retinitis Pigmentosa


Psychological Support By Cognitive Behavioral Therapy For Retinitis Pigmentosa
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Author : Edenilson Brandl
language : en
Publisher: Edenilson Brandl
Release Date :

Psychological Support By Cognitive Behavioral Therapy For Retinitis Pigmentosa written by Edenilson Brandl and has been published by Edenilson Brandl this book supported file pdf, txt, epub, kindle and other format this book has been release on with Psychology categories.


Retinitis Pigmentosa (RP) is a hereditary and progressive eye disease that significantly affects the quality of life of those diagnosed with it. With gradual loss of vision, many individuals face not only physical challenges but also emotional and psychological ones. This book, Psychological Support by Cognitive Behavioral Therapy for Retinitis Pigmentosa, aims to bridge the gap between the medical aspects of RP and the critical mental health support needed by patients navigating this difficult journey. The diagnosis of a genetic disease such as RP often comes with a whirlwind of emotions—shock, fear, anxiety, and sometimes even depression. Many struggle to understand the biological underpinnings of the disease, while also grappling with the emotional toll it can take on daily life, relationships, and future plans. Throughout my work with individuals and families dealing with RP, I have observed a pressing need for a comprehensive approach that addresses both the mental and physical dimensions of this condition. This book is designed for a broad audience, including patients, their families, therapists, and medical professionals. It offers insights into the biology of RP, genetics, epigenetics, and how these factors contribute to the progression of the disease. But more importantly, it provides a framework for emotional and psychological resilience through Cognitive Behavioral Therapy (CBT). By learning to manage thoughts, emotions, and behaviors associated with living with a genetic condition, individuals can take control of their mental health and develop healthy coping mechanisms. The tools presented in this book are rooted in the principles of CBT, one of the most effective therapeutic approaches for managing anxiety, depression, and other mental health challenges. With personalized therapeutic approaches, practical exercises, and case examples, this book serves as a guide to help individuals overcome mental health barriers, foster self-compassion, and regain a sense of control and independence. I hope that this book will offer a sense of hope, empowerment, and guidance for those facing the challenges of Retinitis Pigmentosa. Through understanding the biology behind the disease and harnessing the power of cognitive behavioral therapy, it is possible to not only cope but also thrive despite the difficulties.



Frontiers In Brain Based Therapeutic Interventions And Biomarker Research In Child And Adolescent Psychiatry


Frontiers In Brain Based Therapeutic Interventions And Biomarker Research In Child And Adolescent Psychiatry
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Author : Paul E. Croarkin
language : en
Publisher: Frontiers Media SA
Release Date : 2016-08-05

Frontiers In Brain Based Therapeutic Interventions And Biomarker Research In Child And Adolescent Psychiatry written by Paul E. Croarkin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-05 with Medicine (General) categories.


Developmental neuroscience research is on the cusp of unprecedented advances in the understanding of how variations in brain structure and function within neural circuits confer risk for symptoms of childhood psychiatric disorders. Novel dimensional approaches to illness classification, the availability of non-invasive, diverse and increasingly sophisticated methods to measure brain structure and function in humans in vivo, and advances in genetics, animal model and multimodal research now place brain-based biomarkers within reach in the field of psychiatry. These advances hold great promise for moving neuroscience research into the clinical realm. One exciting new area of translational research in child and adolescent psychiatry, is in the use of a variety of neuroscience research tools to track brain response to clinical intervention. Examples of this include: using longitudinal neuroimaging techniques to track changes in white matter microstructure following a training intervention for children with poor reading skills, or using functional imaging to compare brain activity before and after children with bipolar disorder begin taking psychotropic medication treatment. Brain stimulation is another cutting-edge research area where brain response to therapeutic intervention can be closely tracked with electroencephalography or other brain imaging modalities. Research using neuroscience tools to track brain response to clinical interventions is beginning to yield novel insights into the etiopathogenesis of psychiatric illness, and is providing preliminary feedback around how therapeutic interventions work in the brain to bring about symptom improvement. Using these novel approaches, neuroscience research may soon move into the clinical realm to target early pathophysiology, and tailor treatments to both individuals and specific neurodevelopmental trajectories, in an effort to alter the course of development and mitigate risk for a lifetime of morbidity and ineffective treatments. Excitement and progress in these areas must be tempered with safety and ethical considerations for these vulnerable populations. This research topic focuses on efforts to use neuroscience research tools to identify brain-based biomarkers of therapeutic response in child and adolescent psychiatry.



Psychological Support By Cognitive Behavioral Therapy For Hyper Igm Syndrome


Psychological Support By Cognitive Behavioral Therapy For Hyper Igm Syndrome
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Author : Edenilson Brandl
language : en
Publisher: Edenilson Brandl
Release Date :

Psychological Support By Cognitive Behavioral Therapy For Hyper Igm Syndrome written by Edenilson Brandl and has been published by Edenilson Brandl this book supported file pdf, txt, epub, kindle and other format this book has been release on with Psychology categories.


In recent years, the understanding of genetic disorders has advanced significantly, shedding light on the intricate interplay between our genetic makeup and psychological well-being. Among these conditions, Hyper-IgM Syndrome stands out, not only for its genetic complexities but also for the profound psychological challenges it poses to those affected and their families. This book aims to bridge the gap between genetic knowledge and psychological support, providing a comprehensive resource for individuals navigating the multifaceted journey of living with Hyper-IgM Syndrome. Hyper-IgM Syndrome is characterized by an inability to produce adequate immunoglobulin G (IgG), resulting in increased susceptibility to infections and a host of other health issues. However, the impact of this syndrome extends far beyond the physical realm. The emotional and psychological toll it takes can lead to feelings of isolation, anxiety, depression, and trauma. Recognizing this, I have dedicated this work to exploring how Cognitive Behavioral Therapy (CBT) can serve as an effective therapeutic approach to address these emotional challenges. The structure of this book is designed to guide readers through various dimensions of Hyper-IgM Syndrome, beginning with a foundational understanding of the condition itself. From trauma and genetic concepts to the principles of CBT, each chapter builds upon the last, creating a comprehensive framework for understanding and addressing both the biological and psychological aspects of the syndrome. Throughout this book, you will find practical tools and strategies rooted in CBT that can empower individuals to manage their symptoms, navigate the complexities of their health journey, and foster resilience. Whether you are a patient, a caregiver, a healthcare professional, or someone simply seeking to understand Hyper-IgM Syndrome better, this book is intended to provide valuable insights and actionable strategies. I would like to express my gratitude to the individuals and families who have shared their stories, insights, and experiences with me. Your courage in facing the challenges of Hyper-IgM Syndrome has inspired this work and underscored the importance of a holistic approach to health that encompasses both mind and body. As you embark on this journey through the pages of this book, I encourage you to engage with the material actively. Whether through self-reflection, journaling, or applying the techniques discussed, I hope you find empowerment and support as you navigate the complexities of Hyper-IgM Syndrome and embrace the possibilities of psychological healing. Thank you for joining me on this journey toward understanding and support.