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Biomedical Applications For Microfluidic Devices


Biomedical Applications For Microfluidic Devices
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Microfluidic Devices For Biomedical Applications


Microfluidic Devices For Biomedical Applications
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Author : Xiujun (James) Li
language : en
Publisher: Elsevier
Release Date : 2013-10-31

Microfluidic Devices For Biomedical Applications written by Xiujun (James) Li and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-31 with Science categories.


Microfluidics or lab-on-a-chip (LOC) is an important technology suitable for numerous applications from drug delivery to tissue engineering. Microfluidic devices for biomedical applications discusses the fundamentals of microfluidics and explores in detail a wide range of medical applications.The first part of the book reviews the fundamentals of microfluidic technologies for biomedical applications with chapters focussing on the materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies. Chapters in part two examine applications in drug discovery and controlled-delivery including micro needles. Part three considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering. The final part of the book covers the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis.Microfluidic devices for biomedical applications is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries. - Discusses the fundamentals of microfluidics or lab-on-a-chip (LOC) and explores in detail a wide range of medical applications - Considers materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies - Considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering



Biomedical Applications Of Microfluidic Devices


Biomedical Applications Of Microfluidic Devices
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Author : Michael R. Hamblin
language : en
Publisher: Academic Press
Release Date : 2020-11-12

Biomedical Applications Of Microfluidic Devices written by Michael R. Hamblin and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-12 with Technology & Engineering categories.


Biomedical Applications of Microfluidic Devices introduces the subject of microfluidics and covers the basic principles of design and synthesis of actual microchannels. The book then explores how the devices are coupled to signal read-outs and calibrated, including applications of microfluidics in areas such as tissue engineering, organ-on-a-chip devices, pathogen identification, and drug/gene delivery. This book covers high-impact fields (microarrays, organ-on-a-chip, pathogen detection, cancer research, drug delivery systems, gene delivery, and tissue engineering) and shows how microfluidics is playing a key role in these areas, which are big drivers in biomedical engineering research. This book addresses the fundamental concepts and fabrication methods of microfluidic systems for those who want to start working in the area or who want to learn about the latest advances being made. The subjects covered are also an asset to companies working in this field that need to understand the current state-of-the-art. The book is ideal for courses on microfluidics, biosensors, drug targeting, and BioMEMs, and as a reference for PhD students. The book covers the emerging and most promising areas of biomedical applications of microfluidic devices in a single place and offers a vision of the future. - Covers basic principles and design of microfluidics devices - Explores biomedical applications to areas such as tissue engineering, organ-on-a-chip, pathogen identification, and drug and gene delivery - Includes chemical applications in organic and inorganic chemistry - Serves as an ideal text for courses on microfluidics, biosensors, drug targeting, and BioMEMs, as well as a reference for PhD students



Biomedical Applications For Microfluidic Devices


Biomedical Applications For Microfluidic Devices
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Author : Wen Qiao
language : en
Publisher:
Release Date : 2013

Biomedical Applications For Microfluidic Devices written by Wen Qiao and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with categories.


My thesis research has focused on the biomedical applications of microfluidic devices, including accommodating liquid intraocular lens, wirelessly powered dielectrophoresis microfluidic platform, and evaporative microarray for molecular in-vitro diagnosis. In the first part, I developed an accommodating intraocular lens that can largely improve cataract patients' living quality by enabling patients to focus on far distance as well as near distance. Compared to natural eyes, today's commercially available accommodating IOLs produce a much limited tuning range. The large performance gap is attributed to the fundamental difference between crystalline lens and the optic-shift IOLs in the operation principles. In the thesis we designed and made a fluidic IOL that can change its curvature as the crystalline lens does. Both mechanical performance and optical quality are tested under the physiological conditions of aged eyes, promising complete restoration of vision accommodation. In the second part, I reported the first microfluidic device integrated with a printed RF circuit so that the device can be wirelessly powered by a commerciallyavailable radio-frequency identification (RFID) reader. The device eliminates the need for wire attachments and external instrument, so the operators can use the device in essentially the same manner as they do with microscope slides. The integrated circuit can be fabricated on a flexible plastic substrate at very low cost using a roll-to-roll printing method. Electrical power at 13.56 MHz transmitted by a RFID reader is inductively coupled to the printed RFIC and converted into 10V DC (direct current) output, which provides sufficient power to drive a microfluidic device to manipulate biological particles such as beads and proteins via the DC dielectrophoresis (DC-DEP) effect. In the third part, I developed a mathematical model for microarray probe/target reaction. The analysis was based on any chemical reaction between target molecules suspended in solution react and probes immobilized on a solid substrate, so it can be used to analysis hybridization efficiency in genomic microarray, as well as binding efficiency in protein microarray. The model indicated that besides diffusion, electrical repelling force between negatively charged probe and target molecules is the main cause for low hybridization efficiency. Based on the model, we further proposed a novel evaporative microarray, which can reduce the target solution thickness down to 80 [mu]m and theoretically enrich the concentration of molecules up to 1000 fold before target/probe chemical reaction. Preliminary data demonstrated the feasibility of integration of evaporation with microarray using black silicon template.



Microfluidic Technologies For Human Health


Microfluidic Technologies For Human Health
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Author : Utkan Demirci
language : en
Publisher: World Scientific
Release Date : 2012

Microfluidic Technologies For Human Health written by Utkan Demirci and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.


The field of microfluidics has in the last decade permeated many disciplines, from physics to biology and chemistry, and from bioengineering to medical research. One of the most important applications of lab-on-a-chip devices in medicine and related disciplines is disease diagnostics, which involves steps from biological sample/analyte loading to storage, detection, and analysis. The chapters collected in this book detail recent advances in these processes using microfluidic devices and systems. The reviews of portable devices for diagnostic purposes are likely to evoke interest and raise new research questions in interdisciplinary fields (e.g., efficient MEMS/microfluidic engineering driven by biological and medical applications).The variety of the selected topics (general relevance of microfluidics in medical and bioengineering research, fabrication, advances in on-chip sample detection and analysis, and specific disease models) ensures that each of them can be viewed in the larger context of microfluidic-mediated diagnostics.



Advanced Microfluidics Based Point Of Care Diagnostics


Advanced Microfluidics Based Point Of Care Diagnostics
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Author : Raju Khan
language : en
Publisher: CRC Press
Release Date : 2022-03-10

Advanced Microfluidics Based Point Of Care Diagnostics written by Raju Khan and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-10 with Medical categories.


This book provides a well-focused and comprehensive overview of novel technologies involved in advanced microfluidics based diagnosis via various types of prognostic and diagnostic biomarkers. This authors examine microfluidics based diagnosis in the biomedical field as an upcoming field with extensive applications. It provides a unique approach and comprehensive technology overview for diagnosis management towards early stages of various bioanalytes via cancer diagnostics diabetes, alzheimer disease, toxicity in food products, brain and retinal diseases, cardiovascular diseases, and bacterial infections etc. Thus, this book would encompass a combinatorial approach of medical science, engineering and biomedical technology. The authors provide a well-focused and comprehensive overview of novel technologies involved in advanced microfluidics based diagnosis via various types of prognostic and diagnostic biomarkers. Moreover, this book contains detailed description on the diagnosis of novel techniques. This book would serve as a guide for students, scientists, researchers, and microfluidics based point of care technologies via smart diagnostics and to plan future research in this valuable field.



Biological Applications Of Microfluidics


Biological Applications Of Microfluidics
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Author : Frank A. Gomez
language : en
Publisher: John Wiley & Sons
Release Date : 2008-02-15

Biological Applications Of Microfluidics written by Frank A. Gomez and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-15 with Science categories.


Microfluidics has numerous potential applications in biotechnology, pharmaceuticals, the life sciences, defense, public health, and agriculture. This book details recent advances in the biological applications of microfluidics, including cell sorting, DNA sequencing on-a-chip, microchip capillary electrophoresis, and synthesis on a microfluidic format. It covers microfabricated LOC technologies, advanced microfluidic tools, microfluidic culture platforms for stem cell and neuroscience research, and more. This is an all-in-one, hands-on resource for analytical chemists and researchers and an excellent text for students.



Micro Nanofluidics And Lab On Chip Based Emerging Technologies For Biomedical And Translational Research Applications Part B


Micro Nanofluidics And Lab On Chip Based Emerging Technologies For Biomedical And Translational Research Applications Part B
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Author :
language : en
Publisher: Academic Press
Release Date : 2022-01-28

Micro Nanofluidics And Lab On Chip Based Emerging Technologies For Biomedical And Translational Research Applications Part B written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-28 with Science categories.


Micro/Nanofluidics and Lab-on-Chip Based Emerging Technologies for Biomedical and Translational Research Applications - Part B, Volume 187 represents the collation of chapters written by eminent scientists worldwide. Chapters in this new release include Design and fabrication of microfluidics devices for molecular biology applications, Micro/Nanofluidics devices for drug delivery, From organ-on-chip to body-on-chip: the next generation of microfluidics platforms for in vitro drug toxicity testing, Micro/Nanofluidics for high throughput drug screening, Design, fabrication and assembly of lab-on-a-chip and its uses, Advances in microfluidic 3D cell culture for pre-clinical drug development, Tissue and organ culture on lab-on-a chip for biomedical applications, and much more. - Offers a basic understanding of the state-of-the-art design and fabrication of microfluidics/ nanofluidics and lab on chip - Explains how to develop microfluidics/nanofluidic for advanced application such as healthcare, high throughout drug screening, 3D cell culture and organ-on-chip - Discusses the emerging demands and research of micro/nanofluidic based devices in biomedical and translational research applications



Microfluidics In Pharmaceutical Sciences


Microfluidics In Pharmaceutical Sciences
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Author : Dimitrios A. Lamprou
language : en
Publisher: Springer Nature
Release Date : 2024-06-21

Microfluidics In Pharmaceutical Sciences written by Dimitrios A. Lamprou and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-21 with Medical categories.


The book covers the basics of microfluidics, current applications in areas such as formulation, drug delivery, drug screening and development, monitoring and diagnostics, and case studies from a teaching perspective to undergraduate and postgraduate students, allowing application of the content in a flipped classroom. Multiple choice questions are included at the end of each chapter. All chapter authors are pioneers and world leaders. This is an ideal book for students, researchers, and industry professionals working on microfluidics in the pharmaceutical sciences.



Multifunctional Hydrogels For Biomedical Applications


Multifunctional Hydrogels For Biomedical Applications
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Author : Ricardo A. Pires
language : en
Publisher: John Wiley & Sons
Release Date : 2022-05-12

Multifunctional Hydrogels For Biomedical Applications written by Ricardo A. Pires and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-12 with Technology & Engineering categories.


Multifunctional Hydrogels for Biomedical Applications Comprehensive resource presenting a thorough overview of the biomedical applications of hydrogels This book provides an overview of the development and applications of the clinically relevant hydrogels that are used particularly in tissue engineering, regenerative medicine, and drug delivery. Taking a multidisciplinary approach, it goes through the material from chemistry, materials science, biology, medicine, nanotechnology, and bioengineering points of view. Sample topics covered by the three well-qualified editors include: The design, functions, and developments of hydrogels Proteins and polysaccharides that mimic extracellular matrix Generation and applications of supramolecular hydrogels Design and functions of cell encapsulation systems Multifunctional Hydrogels for Biomedical Applications is a useful all-in-one reference work for materials scientists, polymer chemists, and bioengineers which provides a comprehensive, contemporary understanding of hydrogels and their applications targeting a wide variety of pathologies.



Microfluidics For Pharmaceutical Applications


Microfluidics For Pharmaceutical Applications
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Author : Hélder A. Santos
language : en
Publisher: William Andrew
Release Date : 2018-10-12

Microfluidics For Pharmaceutical Applications written by Hélder A. Santos and has been published by William Andrew this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-12 with Technology & Engineering categories.


Microfluidics for Pharmaceutical Applications: From Nano/Micro Systems Fabrication to Controlled Drug Delivery is a concept-orientated reference that features case studies on utilizing microfluidics for drug delivery applications. It is a valuable learning reference on microfluidics for drug delivery applications and assists practitioners developing novel drug delivery platforms using microfluidics. It explores advances in microfluidics for drug delivery applications from different perspectives, covering device fabrication, fluid dynamics, cutting-edge microfluidic technology in the global drug delivery industry, lab-on-chip nano/micro fabrication and drug encapsulation, cell encapsulation and delivery, and cell- drug interaction screening. These microfluidic platforms have revolutionized the drug delivery field, but also show great potential for industrial applications. - Presents detailed coverage on the fabrication of novel drug delivery systems with desired characteristics, such as uniform size, Janus particles, and particular or combined responsiveness - Includes a variety of case studies that explain principles - Focuses on commercialization, cost, safety, society and educational issues of microfluidic applications, showing how microfluidics is used in the real world