Biomolecular Imaging At High Spatial And Temporal Resolution In Vitro And In Vivo

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Biomolecular Imaging At High Spatial And Temporal Resolution In Vitro And In Vivo

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Author : Thomas Harry Sharp
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-10-31

Biomolecular Imaging At High Spatial And Temporal Resolution In Vitro And In Vivo written by Thomas Harry Sharp and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-31 with Science categories.

As part of a collaboration between two different groups in chemistry and biochemistry, Thom Sharp presents here his thesis work on the development of new methods for cryoelectron microscopy. Throughout his Ph.D., Thom had to master a whole range of techniques including modelling, molecular biology and microscopy. Using these skills to tackle an outstanding problem, the pursuit of high-resolution structures of peptide-based materials, Thom highlights in this thesis his newly developed methods for analysing and processing this particular type of electron microscopy data. This thesis gives the first molecular description of a de-novo designed peptide-based material. In general, this research will have a huge impact on the peptide assembly field, and also in electron microscopy as it introduces new methods and approaches, all of which are Thom's inventions and are described in this thesis.

Biomolecular Imaging At High Spatial And Temporal Resolution In Vitro And In Vivo

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Author : Thomas H. Sharp
language : en
Publisher:
Release Date : 2013-11-30

Biomolecular Imaging At High Spatial And Temporal Resolution In Vitro And In Vivo written by Thomas H. Sharp and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-30 with categories.

Biomolecular Imaging At High Spatial And Temporal Resolution In Vitro And In Vivo

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Author : Thomas Harry Sharp
language : en
Publisher: Springer
Release Date : 2013-11-12

Biomolecular Imaging At High Spatial And Temporal Resolution In Vitro And In Vivo written by Thomas Harry Sharp and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-12 with Science categories.

As part of a collaboration between two different groups in chemistry and biochemistry, Thom Sharp presents here his thesis work on the development of new methods for cryoelectron microscopy. Throughout his Ph.D., Thom had to master a whole range of techniques including modelling, molecular biology and microscopy. Using these skills to tackle an outstanding problem, the pursuit of high-resolution structures of peptide-based materials, Thom highlights in this thesis his newly developed methods for analysing and processing this particular type of electron microscopy data. This thesis gives the first molecular description of a de-novo designed peptide-based material. In general, this research will have a huge impact on the peptide assembly field, and also in electron microscopy as it introduces new methods and approaches, all of which are Thom's inventions and are described in this thesis.

Fluorescence Based Biosensors

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Author :
language : en
Publisher: Academic Press
Release Date : 2012-12-31

Fluorescence Based Biosensors written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-31 with Science categories.

One of the major challenges of modern biology and medicine consists in finding means to visualize biomolecules in their natural environment with the greatest level of accuracy, so as to gain insight into their properties and behaviour in a physiological and pathological setting. This has been achieved thanks to the design of novel imaging agents, in particular to fluorescent biosensors. Fluorescence Biosensors comprise a large set of tools which are useful for fundamental purposes as well as for applications in biomedicine, drug discovery and biotechnology. These tools have been designed and engineered thanks to the combined efforts of chemists and biologists over the last decade, and developed hand in hand together with imaging technologies. This volume will convey the many exciting developments the field of fluorescent biosensors and reporters has witnessed over the recent years, from concepts to applications, including chapters on the chemistry of fluorescent probes, on technologies for monitoring protein/protein interactions and technologies for imaging biosensors in cultured cells and in vivo. Other chapters are devoted to specific examples of genetically-encoded reporters, or to protein and peptide biosensors, together with examples illustrating their application to cellular and in vivo imaging, biomedical applications, drug discovery and high throughput screening. - Contributions from leading authorities - Informs and updates on all the latest developments in the field

Modern Spectroscopic Techniques For Drug Discovery And Environmental Sustainability

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Author : Prakash, Om
language : en
Publisher: IGI Global
Release Date : 2025-04-10

Modern Spectroscopic Techniques For Drug Discovery And Environmental Sustainability written by Prakash, Om and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-10 with Science categories.

Modern spectroscopic techniques play a pivotal role in advancing both drug discovery and environmental sustainability, offering precise and efficient methods for analyzing complex molecular structures and interactions. In the field of drug discovery, techniques like nuclear magnetic resonance, mass spectrometry, and infrared spectroscopy enable researchers to identify potential drug candidates, monitor their behavior in biological systems, and optimize their safety profiles. Spectroscopic methods in environmental science are used to detect pollutants, monitor ecosystem health, and evaluate the impact of human activity on the environment. Further research into modern spectroscopic techniques may accelerate scientific discovery while supporting sustainable practices aimed at preserving human health and environmental well-being. Modern Spectroscopic Techniques for Drug Discovery and Environmental Sustainability explores the various aspects of spectroscopy in drug discovery and environmental sustainability. It examines techniques in spectroscopic technology for improving the organized efforts in dealing with drug development and sustainable practices. This book covers topics such as nutrient analysis, infrared technology, and biomarkers, and is a useful resource for environmental scientists, drug developers, biologists, academicians, and researchers.

Biomedical Engineering Concepts Methodologies Tools And Applications

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Author : Management Association, Information Resources
language : en
Publisher: IGI Global
Release Date : 2017-07-13

Biomedical Engineering Concepts Methodologies Tools And Applications written by Management Association, Information Resources and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-13 with Technology & Engineering categories.

Technological tools and computational techniques have enhanced the healthcare industry. These advancements have led to significant progress and novel opportunities for biomedical engineering. Biomedical Engineering: Concepts, Methodologies, Tools, and Applications is an authoritative reference source for emerging scholarly research on trends, techniques, and future directions in the field of biomedical engineering technologies. Highlighting a comprehensive range of topics such as nanotechnology, biomaterials, and robotics, this multi-volume book is ideally designed for medical practitioners, professionals, students, engineers, and researchers interested in the latest developments in biomedical technology.

Fluorescent Methods For Molecular Motors

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Author : Christopher P. Toseland
language : en
Publisher: Springer
Release Date : 2014-08-05

Fluorescent Methods For Molecular Motors written by Christopher P. Toseland and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-05 with Science categories.

This book focuses on the application of fluorescence to study motor proteins (myosins, kinesins, DNA helicases and RNA polymerases). It is intended for a large community of biochemists, biophysicists and cell biologists who study a diverse collection of motor proteins. It can be used by researchers to gain an insight into their first experiments, or by experienced researchers who are looking to expand their research to new areas. Each chapter provides valuable advice for executing the experiments, along with detailed background knowledge in order to develop own experiments.

21st Century Nanoscience A Handbook

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Author : Klaus D. Sattler
language : en
Publisher: CRC Press
Release Date : 2020-04-02

21st Century Nanoscience A Handbook written by Klaus D. Sattler and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-02 with Science categories.

This up-to-date reference is the most comprehensive summary of the field of nanoscience and its applications. It begins with fundamental properties at the nanoscale and then goes well beyond into the practical aspects of the design, synthesis, and use of nanomaterials in various industries. It emphasizes the vast strides made in the field over the past decade – the chapters focus on new, promising directions as well as emerging theoretical and experimental methods. The contents incorporate experimental data and graphs where appropriate, as well as supporting tables and figures with a tutorial approach.

21st Century Nanoscience

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Author : Klaus D. Sattler
language : en
Publisher: CRC Press
Release Date : 2022-01-18

21st Century Nanoscience written by Klaus D. Sattler and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-18 with Science categories.

This 21st Century Nanoscience Handbook will be the most comprehensive, up-to-date large reference work for the field of nanoscience. Handbook of Nanophysics, by the same editor, published in the fall of 2010, was embraced as the first comprehensive reference to consider both fundamental and applied aspects of nanophysics. This follow-up project has been conceived as a necessary expansion and full update that considers the significant advances made in the field since 2010. It goes well beyond the physics as warranted by recent developments in the field. Key Features: Provides the most comprehensive, up-to-date large reference work for the field. Chapters written by international experts in the field. Emphasises presentation and real results and applications. This handbook distinguishes itself from other works by its breadth of coverage, readability and timely topics. The intended readership is very broad, from students and instructors to engineers, physicists, chemists, biologists, biomedical researchers, industry professionals, governmental scientists, and others whose work is impacted by nanotechnology. It will be an indispensable resource in academic, government, and industry libraries worldwide. The fields impacted by nanoscience extend from materials science and engineering to biotechnology, biomedical engineering, medicine, electrical engineering, pharmaceutical science, computer technology, aerospace engineering, mechanical engineering, food science, and beyond.

New Frontiers In Ultrasensitive Bioanalysis

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Author : Xiao-Hong Nancy Xu
language : en
Publisher: John Wiley & Sons
Release Date : 2007-06-04

New Frontiers In Ultrasensitive Bioanalysis written by Xiao-Hong Nancy Xu and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-06-04 with Science categories.

An overview of current research and developments in ultrasensitive bioanalysis New platforms of ultrasensitive analysis of biomolecules and single living cells using multiplexing, single nanoparticle sensing, nano-fluidics, and single-molecule detection are advancing every scientific discipline at an unprecedented pace. With chapters written by a diverse group of scientists working in the forefront of ultrasensitive bioanalysis, this book provides an overview of the current status and an in-depth understanding of the objectives and future research directions of ultrasensitive bioanalysis. Spanning a wide spectrum of new research approaches, this book: Introduces new theories, ideas, methodologies, technologies, and applications of ultrasensitive bioanalysis in a wide variety of research fields Includes background, fundamentals, and descriptions of instrumentation and techniques behind every experimental design and approach to help readers explore the promising applications of new tools Covers single molecule detection (SMD), single living cell analysis, multi-functional nanoparticle probes, miniaturization, multiplexing, quantitative and qualitative analysis of metal ions and small molecules, and more Discusses techniques such as single molecule microscope and spectroscopy, single nanoparticle optics, single nanoparticle sensors, micro- and nano-fluidics, microarray detection, ultramicroelectrodes, electrochemiluminescence, mass spectrometry, and more This book will be a useful resource and an inspiration for scientists and graduate and undergraduate students in a wide variety of research fields, including chemistry, biology, biomedical science and engineering, and materials science and engineering.