Biophysical Approaches For The Study Of Membrane Structure Part B
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Biophysical Approaches For The Study Of Membrane Structure Part B
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Author :
language : en
Publisher: Elsevier
Release Date : 2024-07-21
Biophysical Approaches For The Study Of Membrane Structure Part B written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-21 with Science categories.
Biophysical Approaches for the Study of Membrane Structure, Part B, Volume 701 explores lipid membrane asymmetry and lateral heterogeneity. A burst of recent research has shown that bilayers whose leaflets differ in their physical properties—such as composition, phase state, or lateral stress—exhibit many fascinating new characteristics, but also pose a host of challenges related to their creation, characterization, simulation, and theoretical description. Chapters in this new release include Characterization of domain formation in complex membranes: Analyzing the bending modulus from simulations of complex membranes, The density-threshold affinity: Calculating lipid binding affinities from unbiased Coarse-Grain Molecular Dynamics simulations, and much more.Additional sections cover Uncertainty quantification for trans-membrane stresses and moments from simulation, Using molecular dynamics simulations to generate small-angle scattering curves and cryo-EM images of proteoliposomes, Binary Bilayer Simulations for Partitioning Within Membranes, Modeling Asymmetric Cell Membranes at All-atom Resolution, Multiscale remodeling of biomembranes and vesicles, Building complex membranes with Martini 3, Predicting lipid sorting in curved bilayer membranes, Simulating asymmetric membranes using P21 periodic boundary conditions, and many other interesting topics. - Explore the state-of-the-art of lipid membrane asymmetry - Covers experimental, theoretical, and computational techniques to create and characterize asymmetric lipid membranes - Teaches how these kinds of approaches create and characterize laterally inhomogeneous membranes
Biophysical Approaches For The Study Of Membrane Structure Part A
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Author :
language : en
Publisher: Elsevier
Release Date : 2024-07-05
Biophysical Approaches For The Study Of Membrane Structure Part A written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-05 with Science categories.
Biophysical Approaches for the Study of Membrane Structure, Part A, Volume 700 explores lipid membrane asymmetry and lateral heterogeneity. A burst of recent research has shown that bilayers whose leaflets differ in their physical properties—such as composition, phase state, or lateral stress—exhibit many fascinating new characteristics, but also pose a host of new challenges related to their creation, characterization, simulation, and theoretical description. Chapters in this new release include Evaluation of functional transbilayer coupling in live cells by controlled lipid exchange and imaging FCS, Effects of lateral and hydrostatic pressure on membrane structure and properties, and much more.Other sections cover Using the yeast vacuole as a system to test the lipid drivers of membrane heterogeneity in living cells, Direct quantification of cellular membrane lipids using ratiometric fluorescence sensors, The spectral phasor approach to resolving membrane order with environmentally sensitive dyes, The use of hemifusion to create asymmetric giant unilamellar vesicles: Insights on induced order domains, Advanced microscopy methods to study membrane pores, Use of cryo-EM to study membrane phase separation, and much more. - Explore the state-of-the-art of lipid membrane asymmetry - Covers experimental, theoretical, and computational techniques to create and characterize asymmetric lipid membranes - Teaches how these kinds of approaches create and characterize laterally inhomogeneous membranes
Chemical And Biochemical Approaches For The Study Of Anesthetic Function Part B
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Author :
language : en
Publisher: Academic Press
Release Date : 2018-04-16
Chemical And Biochemical Approaches For The Study Of Anesthetic Function Part B written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-16 with Science categories.
Chemical and Biochemical Approaches for the Study of Anesthetic Function, Part B, Volume 603, presents a coherent description of the campaign towards understanding anesthesia. It includes a variety of highly debated topics, including sections on computational approaches, best practices for simulating ligand-gated ion channels interacting with general anesthetics, computational approaches for studying voltage-gated ion channels modulation by general anesthetics, anesthetic parameterization, the kinetic modeling of electrophysiology data, evolving biophysical technologies, fluorescent anesthetics, lipids, membranes and pressure reversal, in vivo technologies, and more. - Helps readers understand the wide array of topics surrounding anesthesia - Includes sections on Pharmacophore QSAR, QM, ONIOM, and the kinetic modeling of electrophysiology data - Broaches genetics, model organisms and general genetic strategies
Liposomes Part B
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Author : Nejat Duzgunes
language : en
Publisher: Elsevier
Release Date : 2003-11-19
Liposomes Part B written by Nejat Duzgunes and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-11-19 with Science categories.
Liposomes are cellular structures made up of lipid molecules. Important as a cellular model in the study of basic biology, liposomes are also used in clinical applications such as drug delivery and virus studies. - Liposomes in Biochemistry - Liposomes in Molecular Cell Biology - Liposomes in Molecular Virology
Computational Approaches For Studying Enzyme Mechanism Part B
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Author :
language : en
Publisher: Academic Press
Release Date : 2016-08-03
Computational Approaches For Studying Enzyme Mechanism Part B written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-03 with Science categories.
Computational Approaches for Studying Enzyme Mechanism, Part B is the first of two volumes in the Methods in Enzymology series that focuses on computational approaches for studying enzyme mechanism. The serial achieves the critically acclaimed gold standard of laboratory practices and remains one of the most highly respected publications in the molecular biosciences. Each volume is eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 550 volumes, the series remains a prominent and essential publication for researchers in all fields of the life sciences and biotechnology, including biochemistry, chemical biology, microbiology, synthetic biology, cancer research, genetics, and other fields of study. - Focuses on computational approaches for studying enzyme mechanism - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers research methods in intermediate filament associated proteins, and contains sections on such topics as lamin-associated proteins, intermediate filament-associated proteins and plakin, and other cytoskeletal cross-linkers
Biophysical Approaches Determining Ligand Binding To Biomolecular Targets
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Author : Alberto Podjarny
language : en
Publisher: Royal Society of Chemistry
Release Date : 2011
Biophysical Approaches Determining Ligand Binding To Biomolecular Targets written by Alberto Podjarny and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Science categories.
This book provides a complete overview of current techniques to identify ligands, characterize their binding sites, and understand binding mechanisms. Suitable for biomolecular scientists at graduate or post-doctoral level in academia and industry.
Methods In Molecular Biophysics
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Author : Igor N. Serdyuk
language : en
Publisher: Cambridge University Press
Release Date : 2017-05-18
Methods In Molecular Biophysics written by Igor N. Serdyuk and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-18 with Medical categories.
A comprehensive graduate textbook explaining key physical methods in biology, reflecting the very latest research in this fast-moving field.
Cell Stress Proteins
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Author : Stuart K. Calderwood
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-02-13
Cell Stress Proteins written by Stuart K. Calderwood and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-02-13 with Science categories.
Stressproteinssuchastheheatshockproteins(Hsp)andglucose-regulatedproteins (Grp) are front-line molecules in responses to cellular insult and play key roles in the viability of single cell organisms exposed to environmental stresses. However, the discovery of the roles of Hsp and Grp as molecular chaperones indicates much wider functions in the physiology of cells and organisms. It is now clear that some stress proteins are expressed constitutively and are key mediators of housekeeping protein folding in the day-to-day existence of the cell. The maturation of enzymes, transcriptionfactors,andcellsurfacereceptorsreliesonthesefunctionsofthestress proteins. In addition, the ability of stress proteins to manipulate the structures of target proteins has lent them cell regulatory properties over and above their role in folding the proteome and they play key roles in controlling signal transduction, cell death pathways and transcription. Recently, novel extracellular roles for the Hsp have also emerged as it has become apparent that the Hsp can escape from the cytoplasm of cells and play a signi?cant extracellular role in signaling to neighbor cells and in immunosurveiIlance. As might be expected with such key molecules, dysregulation of Hsp expression over time can lead to disastrous results in terms of the health of the organism. Under-expression of the Hsp is associated with advanced aging and neurodegeneration. Elevated expression is associated with malignant progression. We have aimed in this volume to indicate advances in each oftheseaspectsofstressproteinresearch,withchaptersrangingfrombasicstudies of the role of Hsp in protein folding to reviews examining the breakdown of stress protein regulation in disease. Stuart K.
Biophysics Of Gap Junction Channels
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Author : M.D. Peracchia
language : en
Publisher: CRC Press
Release Date : 2018-01-18
Biophysics Of Gap Junction Channels written by M.D. Peracchia and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-18 with Medical categories.
This book provides a state of the art account of present knowledge of the biophysics of cell-to-cell channels. It is divided into two sections, one dealing with two-cell systems and the other with reconstitution systems.
Fluorescent Methods To Study Biological Membranes
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Author : Yves Mely
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-10-10
Fluorescent Methods To Study Biological Membranes written by Yves Mely and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-10 with Science categories.
Biological membranes play a central role in cell structure, shape and functions. However, investigating the membrane bilayer has proved to be difficult due to its highly dynamic and anisotropic structure, which generates steep gradients at the nanometer scale. Due to the decisive impact of recently developed fluorescence-based techniques, tremendous advances have been made in the last few years in our understanding of membrane characteristics and functions. In this context, the present book illustrates some of these major advances by collecting review articles written by highly respected experts. The book is organized in three parts, the first of which deals with membrane probes and model membranes. The second part describes the use of advanced quantitative and high-resolution techniques to explore the properties of biological membranes, illustrating the key progress made regarding membrane organization, dynamics and interactions. The third part is focused on the investigation of membrane proteins using the same techniques, and notably on the membrane receptors that play a central role in signaling pathways and therapeutic strategies. All chapters provide comprehensive information on membranes and their exploration for beginners in the field and advanced researchers alike.