Biophysically Based Computational Models Of Astrocyte Neuron Coupling And Their Functional Significance
DOWNLOAD
Download Biophysically Based Computational Models Of Astrocyte Neuron Coupling And Their Functional Significance PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Biophysically Based Computational Models Of Astrocyte Neuron Coupling And Their Functional Significance book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Biophysically Based Computational Models Of Astrocyte Neuron Coupling And Their Functional Significance
DOWNLOAD
Author : John Wade
language : en
Publisher: Frontiers E-books
Release Date : 2014-03-21
Biophysically Based Computational Models Of Astrocyte Neuron Coupling And Their Functional Significance written by John Wade and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-21 with categories.
Neuroscientists are increasingly becoming more interested in modelling brain functions where capturing the biophysical mechanisms underpinning these functions requires plausible models at the level of neuron cells. However, cell level models are still very much in the embryo stage and therefore there is a need to advance the level of biological realism at the level of neurons/synapses. Recent publications have highlighted that astrocytes continually exchange information with multiple synapses; if we are to fully appreciate this dynamic and coordinated interplay between these cells then more research on bidirectional signalling between astrocytes and neurons is required. A better understanding of astrocyte-neuron cell coupling would provide the building block for studying the regulatory capability of astrocytes networks on a large scale. For example, it is believed that local and global signalling via astrocytes underpins brain functions like synchrony, learning, memory and self repair. This Research Topic aims to report on current research work which focuses on understanding and modelling the interaction between astrocytes and neurons at the cellular level (Bottom up) and at network level (Top down). Understanding astrocytic regulation of neural activity is crucial if we are to capture how information is represented and processed across large neuronal ensembles in humans.
Reproducibility And Rigour In Computational Neuroscience
DOWNLOAD
Author : Sharon Crook
language : en
Publisher: Frontiers Media SA
Release Date : 2020-07-09
Reproducibility And Rigour In Computational Neuroscience written by Sharon Crook and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-09 with categories.
Metastable Dynamics Of Neural Ensembles
DOWNLOAD
Author : Emili Balaguer-Ballester
language : en
Publisher: Frontiers Media SA
Release Date : 2018-03-19
Metastable Dynamics Of Neural Ensembles written by Emili Balaguer-Ballester and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-19 with categories.
A classical view of neural computation is that it can be characterized in terms of convergence to attractor states or sequential transitions among states in a noisy background. After over three decades, is this still a valid model of how brain dynamics implements cognition? This book provides a comprehensive collection of recent theoretical and experimental contributions addressing the question of stable versus transient neural population dynamics from complementary angles. These studies showcase recent efforts for designing a framework that encompasses the multiple facets of metastability in neural responses, one of the most exciting topics currently in systems and computational neuroscience.
Criticality In Neural Systems
DOWNLOAD
Author : Dietmar Plenz
language : en
Publisher: John Wiley & Sons
Release Date : 2014-04-14
Criticality In Neural Systems written by Dietmar Plenz and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-14 with Computers categories.
Neurowissenschaftler suchen nach Antworten auf die Fragen, wie wir lernen und Information speichern, welche Prozesse im Gehirn verantwortlich sind und in welchem Zeitrahmen diese ablaufen. Die Konzepte, die aus der Physik kommen und weiterentwickelt werden, können in Medizin und Soziologie, aber auch in Robotik und Bildanalyse Anwendung finden. Zentrales Thema dieses Buches sind die sogenannten kritischen Phänomene im Gehirn. Diese werden mithilfe mathematischer und physikalischer Modelle beschrieben, mit denen man auch Erdbeben, Waldbrände oder die Ausbreitung von Epidemien modellieren kann. Neuere Erkenntnisse haben ergeben, dass diese selbstgeordneten Instabilitäten auch im Nervensystem auftreten. Dieses Referenzwerk stellt theoretische und experimentelle Befunde internationaler Gehirnforschung vor zeichnet die Perspektiven dieses neuen Forschungsfeldes auf.
Artificial Neural Networks And Machine Learning Icann 2018
DOWNLOAD
Author : Věra Kůrková
language : en
Publisher: Springer
Release Date : 2018-10-02
Artificial Neural Networks And Machine Learning Icann 2018 written by Věra Kůrková and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-02 with Computers categories.
This three-volume set LNCS 11139-11141 constitutes the refereed proceedings of the 27th International Conference on Artificial Neural Networks, ICANN 2018, held in Rhodes, Greece, in October 2018. The papers presented in these volumes was carefully reviewed and selected from total of 360 submissions. They are related to the following thematic topics: AI and Bioinformatics, Bayesian and Echo State Networks, Brain Inspired Computing, Chaotic Complex Models, Clustering, Mining, Exploratory Analysis, Coding Architectures, Complex Firing Patterns, Convolutional Neural Networks, Deep Learning (DL), DL in Real Time Systems, DL and Big Data Analytics, DL and Big Data, DL and Forensics, DL and Cybersecurity, DL and Social Networks, Evolving Systems – Optimization, Extreme Learning Machines, From Neurons to Neuromorphism, From Sensation to Perception, From Single Neurons to Networks, Fuzzy Modeling, Hierarchical ANN, Inference and Recognition, Information and Optimization, Interacting with The Brain, Machine Learning (ML), ML for Bio Medical systems, ML and Video-Image Processing, ML and Forensics, ML and Cybersecurity, ML and Social Media, ML in Engineering, Movement and Motion Detection, Multilayer Perceptrons and Kernel Networks, Natural Language, Object and Face Recognition, Recurrent Neural Networks and Reservoir Computing, Reinforcement Learning, Reservoir Computing, Self-Organizing Maps, Spiking Dynamics/Spiking ANN, Support Vector Machines, Swarm Intelligence and Decision-Making, Text Mining, Theoretical Neural Computation, Time Series and Forecasting, Training and Learning.
The Role Of Astroglia And Oligodendroglia In Cns Development Plasticity And Disease Novel Tools And Investigative Approaches
DOWNLOAD
Author : Enrica Boda
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-31
The Role Of Astroglia And Oligodendroglia In Cns Development Plasticity And Disease Novel Tools And Investigative Approaches written by Enrica Boda and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-31 with Science categories.
Augmentation Of Brain Function Facts Fiction And Controversy
DOWNLOAD
Author : Ioan Opris
language : en
Publisher: Frontiers Media SA
Release Date : 2018-09-14
Augmentation Of Brain Function Facts Fiction And Controversy written by Ioan Opris and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-14 with Neurosciences. Biological psychiatry. Neuropsychiatry categories.
The Volume II is entitled “Neurostimulation and pharmacological approaches”. This volume describes augmentation approaches, where improvements in brain functions are achieved by modulation of brain circuits with electrical or optical stimulation, or pharmacological agents. Activation of brain circuits with electrical currents is a conventional approach that includes such methods as (i) intracortical microstimulation (ICMS), (ii) transcranial direct current stimulation (tDCS), and (iii) transcranial magnetic stimulation (TMS). tDCS and TMS are often regarded as noninvasive methods. Yet, they may induce long-lasting plastic changes in the brain. This is why some authors consider the term “noninvasive” misleading when used to describe these and other techniques, such as stimulation with transcranial lasers. The volume further discusses the potential of neurostimulation as a research tool in the studies of perception, cognition and behavior. Additionally, a notion is expressed that brain augmentation with stimulation cannot be described as a net zero sum proposition, where brain resources are reallocated in such a way that gains in one function are balanced by costs elsewhere. In recent years, optogenetic methods have received an increased attention, and several articles in Volume II cover different aspects of this technique. While new optogenetic methods are being developed, the classical electrical stimulation has already been utilized in many clinically relevant applications, like the vestibular implant and tactile neuroprosthesis that utilizes ICMS. As a peculiar usage of neurostimulation and pharmacological methods, Volume II includes several articles on augmented memory. Memory prostheses are a popular recent development in the stimulation-based BMIs. For example, in a hippocampal memory prosthesis, memory content is extracted from hippocampal activity using a multiple-input, multiple-output non-linear dynamical model. As to the pharmacological approaches to augmenting memory and cognition, the pros and cons of using nootropic drugs are discussed.
Computational Glioscience
DOWNLOAD
Author : Maurizio De Pittà
language : en
Publisher: Springer
Release Date : 2019-01-21
Computational Glioscience written by Maurizio De Pittà and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-21 with Medical categories.
Over the last two decades, the recognition that astrocytes - the predominant type of cortical glial cells - could sense neighboring neuronal activity and release neuroactive agents, has been instrumental in the uncovering of many roles that these cells could play in brain processing and the storage of information. These findings initiated a conceptual revolution that leads to rethinking how brain communication works since they imply that information travels and is processed not just in the neuronal circuitry but in an expanded neuron-glial network. On the other hand the physiological need for astrocyte signaling in brain information processing and the modes of action of these cells in computational tasks remain largely undefined. This is due, to a large extent, both to the lack of conclusive experimental evidence, and to a substantial lack of a theoretical framework to address modeling and characterization of the many possible astrocyte functions. This book that we propose aims at filling this gap, providing the first systematic computational approach to the complex, wide subject of neuron-glia interactions. The organization of the book is unique insofar as it considers a selection of “hot topics” in glia research that ideally brings together both the novelty of the recent experimental findings in the field and the modelling challenge that they bear. A chapter written by experimentalists, possibly in collaboration with theoreticians, will introduce each topic. The aim of this chapter, that we foresee less technical in its style than in conventional reviews, will be to provide a review as clear as possible, of what is “established” and what remains speculative (i.e. the open questions). Each topic will then be presented in its possible different aspects, by 2-3 chapters by theoreticians. These chapters will be edited in order to provide a “priming” reference for modeling neuron-glia interactions, suitable both for the graduate student and the professional researcher.
Neuronal Networks In Brain Function Cns Disorders And Therapeutics
DOWNLOAD
Author : Carl Faingold
language : en
Publisher: Academic Press
Release Date : 2013-12-26
Neuronal Networks In Brain Function Cns Disorders And Therapeutics written by Carl Faingold and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-26 with Medical categories.
Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: - How the brain carries out important tasks via networks - How these networks interact in normal brain function - Major mechanisms that control network function - The interaction of the normal networks to produce more complex behaviors - How brain disorders can result from abnormal interactions - How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders. - Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant - Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders - Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain - Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available
Molecular Imaging
DOWNLOAD
Author : Brian D. Ross
language : en
Publisher: Academic Press
Release Date : 2021-08-03
Molecular Imaging written by Brian D. Ross and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-03 with Science categories.
The detection and measurement of the dynamic regulation and interactions of cells and proteins within the living cell are critical to the understanding of cellular biology and pathophysiology. The multidisciplinary field of molecular imaging of living subjects continues to expand with dramatic advances in chemistry, molecular biology, therapeutics, engineering, medical physics and biomedical applications. Molecular Imaging: Principles and Practice, Volumes 1 and 2, Second Edition provides the first point of entry for physicians, scientists, and practitioners. This authoritative reference book provides a comprehensible overview along with in-depth presentation of molecular imaging concepts, technologies and applications making it the foremost source for both established and new investigators, collaborators, students and anyone interested in this exciting and important field. - The most authoritative and comprehensive resource available in the molecular-imaging field, written by over 170 of the leading scientists from around the world who have evaluated and summarized the most important methods, principles, technologies and data - Concepts illustrated with over 600 color figures and molecular-imaging examples - Chapters/topics include, artificial intelligence and machine learning, use of online social media, virtual and augmented reality, optogenetics, FDA regulatory process of imaging agents and devices, emerging instrumentation, MR elastography, MR fingerprinting, operational radiation safety, multiscale imaging and uses in drug development - This edition is packed with innovative science, including theranostics, light sheet fluorescence microscopy, (LSFM), mass spectrometry imaging, combining in vitro and in vivo diagnostics, Raman imaging, along with molecular and functional imaging applications - Valuable applications of molecular imaging in pediatrics, oncology, autoimmune, cardiovascular and CNS diseases are also presented - This resource helps integrate diverse multidisciplinary concepts associated with molecular imaging to provide readers with an improved understanding of current and future applications