Biophysics Of Infection
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Biophysics Of Infection
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Author : Mark C. Leake
language : en
Publisher: Springer
Release Date : 2016-05-18
Biophysics Of Infection written by Mark C. Leake and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-18 with Science categories.
This book describes modern biophysical techniques that enable us to understand and examine dynamic processes of infection at the molecular level. Cutting-edge research articles, laboratory protocols, case studies and up-to-date reviews cover topics such as single-molecule observation of DNA replication repair pathways in E. coli; evolution of drug resistance in bacteria; restriction enzymes as barriers to horizontal gene transfer in Staphylococcus aureus; infectious and bacterial pathogen biofilms; killing infectious pathogens through DNA damage; bacterial surfaces in host-pathogen interactions; bacterial gene regulation by riboswitches; transcription regulation in enterobacterial pathogens; the bacterial flagellar motor; initial surface colonization by bacteria; Salmonella Typhi host restrictions; as well as monitoring proton motive force in bacteria; microbial pathogens using digital holography; mathematical modelling of microbial pathogen motility; neutron reflectivity in studying bacterial membranes; force spectroscopy in studying infection and 4D multi-photon imaging to investigate immune responses. The focus is on the development and application of complex techniques and protocols at the interface of life sciences and physics, which increase the physiological relevance of biophysical investigations.
Physical Microbiology
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Author : Guillaume Duménil
language : en
Publisher: Springer Nature
Release Date : 2020-09-07
Physical Microbiology written by Guillaume Duménil and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-07 with Medical categories.
This book emerges from the idea that specific physics-inspired approaches are necessary to understand different stage of bacterial physiology and the infections they cause. Many aspects of bacterial life depend on processes typically described by physical laws: The rheology of biofilms is determined by complex cohesive forces. Physical laws of diffusion are essential to all processes of bacterial metabolism. The formation of the numerous bacterial biomacromolecules require complex self-organization processes and their function are powered by potent molecular motors. Host-pathogen interactions during infection frequently occur in environments determined by fluid mechanics. In this book, different chapters represent research at the interface between microbiology and physics. Topics range from intracellular organization to cell-cell interactions. A good part of the book is devoted to mechanical forces, which are involved in the function of elaborate bacterial nanomachines, chromosome segregation, and cell division. The effect of bacterial toxins provides an example of the alteration of cellular membrane properties by bacteria. Symmetrically, histones from mammalian cells alter bacterial membranes as a defense mechanism during infection. The editors of this book, Guillaume Duménil and Sven van Teeffelen, have selected researchers at the forefront of research in physical microbiology to provide the most recent view in this fast-moving field. The contents of this book are designed to be accessible for scientists with training in biology and for scientists with training in physics. The objective is to provide a fresh perspective on microbiology and infection by highlighting recent multidisciplinary research and favor rapid advances at this fruitful interface.
The Molecular Biology Of Viruses
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Author : John Colter
language : en
Publisher: Elsevier
Release Date : 2012-12-02
The Molecular Biology Of Viruses written by John Colter and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
The Molecular Biology of Viruses is a collection of manuscripts presented at the Third Annual International Symposium of the Molecular Biology of Viruses, held in the University of Alberta, Canada on June 27-30, 1966, sponsored by the Faculty of Medicine of the University of Alberta. This book is organized into eight parts encompassing 36 chapters that emphasize the biosynthetic steps involved in polymer duplication. The first two parts explore the specialized processes of the cycle of virulent and temperate bacteriophage multiplication. These parts also deal with the production, regulation of development, and selectivity of these bacteriophages. The subsequent two parts look into the heterozygosity, mutation, structure, function, and mode of infection of single-stranded DNA and RNA bacteriophages. The discussions then shift to the biological and physicochemical aspects, biosynthesis, translation, genetics, and replication of mammalian DNA and RNA viruses. The concluding parts describe the homology, interaction, functions, mechanism of transformation, metabolism, and carcinogenic activity of oncogenic viruses. This book is of great benefit to biochemists, biophysicists, geneticists, microbiologists, and virologists.
Infection
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Author : M.R. Escobar
language : en
Publisher: Springer
Release Date : 2013-10-20
Infection written by M.R. Escobar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-20 with Medical categories.
This comprehensive treatise on the reticuloendothelial system is a project jointly shared by individual members of the Reticuloendothelial (RE) Society and bio medical scientists in general who are interested in the intricate system of cells and molecular moieties derived from those cells that constitute the RES. It may now be more fashionable in some quarters to consider these cells as part of what is called the mononuc1ear phagocytic system or the lymphoreticular system. Nevertheless, because of historical developments and current interest in the subject by investigators from many diverse areas, it seems advantageous to present in one comprehensive treatise current information and knowledge con cerning basic aspects of the RES, such as morphology, biochemistry, phylogeny and ontogeny, physiology, and pharmacology, as well as c1inical areas inc1uding immunopathology, cancer, infectious diseases, allergy, and hypersensitivity. It is anticipated that, by presenting information concerning these apparently het erogeneous topics under the unifying umbrella of the RES, attention will be focused on the similarities as well as interactions among the cell types constitut ing the RES from the viewpoint of various disciplines. The treatise editors and their editorial board, consisting predominantly of the editors of individual vol umes, are extremely grateful for the enthusiastic cooperation and enormous task undertaken by members of the biomedical community in general and especially by members of the American as well as European and Japanese Reticuloen dothelial Societies.
The Molecular Basis Of Viral Infection
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Author :
language : en
Publisher: Academic Press
Release Date : 2015-01-13
The Molecular Basis Of Viral Infection written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-13 with Science categories.
Virology is in a sense both one of the most important precursors and one of the most significant beneficiaries of structural and cellular molecular biology. Numerous breakthroughs in our understanding of the molecular interactions of viruses with host cells are ready for translation into medically important applications such as the prevention and treatment of viral infections. This book collects a wide variety of examples of frontline research into molecular aspects of viral infections from virological, immunological, cell- and molecular-biological, structural, and theoretical perspectives. Contributors are world leaders in their fields of study and represent prestigious academic and research institutions Review articles vary vastly in scope: some focus on a narrowly defined scientific problem of one particular virus with careful introduction for the non-specialist; others are essays in general and comparative virology with forays into specific viral species or molecules The different perspectives complement each other and collectively the contributions provide an impression of the fast-moving frontlines of virology while showing how the problems have evolved Structural data are presented through high-quality illustrations
Bacterial Adhesion
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Author : Dirk Linke
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-05-10
Bacterial Adhesion written by Dirk Linke and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-10 with Medical categories.
Over the last few years, bacterial adhesion has become a more and more important and active scientific area, but the field lacks communication and scientific exchange between medical and microbiology researchers who work with the relevant biological systems, and biochemists, structural biologists and physicists, who know and understand the physical methods best suited to investigate the phenomenon at the molecular level. The field consequently would benefit from a cross-disciplinary conference enabling such communication. This book tries to bridge the gap between the disciplines.
The Biochemistry Of Poliomyelitis Viruses
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Author : Ernest Kovács
language : en
Publisher: Elsevier
Release Date : 2014-05-16
The Biochemistry Of Poliomyelitis Viruses written by Ernest Kovács and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-16 with Science categories.
The Biochemistry of Poliomyelitis Viruses deals with the interrelationships and differences of positions in the field of poliomyelitis research. This volume presents a general introduction to viruses as to their descriptions and biological, biochemical, and epidemiological aspects. Clinical poliomyelitis, test measurements in the cerebrospinal fluid, and the actions of the poliomyelitis virus are explained. The isolation of the poliomyelitis virus and some aspects of its immunology and serology through refinements of serologic tools and special techniques, plus the state of poliovirus purification, are noted. This book also gives assumptions about the virus' synthetic activities in vivo based on experiments conducted in other viral diseases other than the polio virus. This text also notes that important discoveries such as those made by Gierer and Schramm or Fraenkel-Conrat provide updated poliomyelitis research. Other research studies are taken into consideration and emphasis is given to the biochemical concept of the polio infection and the related features induced during infection such as the presence of tumors. The most promising trend in research is in the study of enzymes of infected cells leading to an understanding of the biochemistry of viral diseases. The use of inference microscopy and X-ray analysis of cell mass is recommended. This book will prove invaluable for microbiologists, disease investigators, clinical workers, and research scientists.
The Viruses
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Author : F Burnet
language : en
Publisher: Elsevier
Release Date : 2012-12-02
The Viruses written by F Burnet and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
The Viruses: Biochemical, Biological, and Biophysical Properties, Volume 2: Plant and Bacterial Viruses deals with the biochemistry, biology, and biophysics of plant viruses. The viruses considered are tobacco and turnip yellow mosaic viruses; tobacco ringspot virus; potato virus X; and bacterial viruses, such as lysogenic bacteria and phages. This volume is organized into 10 chapters and begins with a discussion of the tobacco mosaic virus and other plant viruses, emphasizing the process of infection and synthesis and general features of the host-virus system. The next chapters focus on the purification and protein components of plant viruses; the chemical correlates of biological variability in viruses; and biological cycles of plant viruses in insect vectors. This book describes the bacteriophage, which is considered as a model virus in comparison with typical microorganisms and cellular organelles. It also introduces the reader to the kinetics of phage reproduction; the intracellular multiplication of bacterial viruses; and the process of lysogeny in bacteria. The book concludes with a chapter on irradiation of phage with ultraviolet light, decay of incorporated radiophosphorus (""suicide""), and ionizing radiation (usually X-rays). Biologists, botanists, biochemists, biophysicists, and microbial physiologists will find this book a rich source of information on plant and bacterial viruses.
Nutrition Immunity And Infection
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Author : R. K. Chandra
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Nutrition Immunity And Infection written by R. K. Chandra and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
I welcome the privilege of writing some words of introduction to this important book. Its authors have been courageous in bringing together in one text a triad of topics that cover such large tracts of biomedical sciences as epidemiology, biochemistry, immunology, and clinical medicine. Malnutrition and infection are known to be closely linked, the one promoting the other. The adaptive immune system forms a part of the link since it is responsible for a good deal of defense against infection, and it may be affected adversely by malnutrition and indeed by infection itself. Knowledge in this complex field is of great potential importance because malnutri tion and infection are such dominant features of the ill-health of many of the world's underprivileged people. As this book shows, there is no lack of technical facets for study. There are now so many components of the immune response which can be measured or assessed and so many aspects of nutritional biochemistry which can be studied that the problem is to select what to study and where to begin. Moreover, the great number of variables in the nature of nutritional deficiencies, in types of infections or multiple infections and in the genetic, environmental, and social background of the affected people, all combine to make interpretation and application of findings a speculative business. Descriptions of cause and effect must us ually be provisional rather than definitive.
Emerging Topics In Physical Virology
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Author : Peter G Stockley
language : en
Publisher: World Scientific
Release Date : 2010-03-17
Emerging Topics In Physical Virology written by Peter G Stockley and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-17 with Science categories.
Emerging Topics in Physical Virology is a state-of-the-art account of recent advances in the experimental analysis and modeling of structure, function and dynamics of viruses. It is the first interdisciplinary book that integrates a review of relevant experimental techniques, such as cryo-electron microscopy, atomic force microscopy and mass spectrometry with the latest results on the biophysical and mathematical modeling of viruses. The book comprehensively covers the structure and physical properties of the protein envelopes that encapsulate and hence protect the delicate viral genome, their assembly and disassembly, the organization of the viral genome, infection, evolution, as well as applications of viruses in Biomedical Nanotechnology. It is an essential primer for scientists working in all aspects of virology, including the increasing use of viruses and virus-like particles in bio- and nano-technology. Its review style makes it moreover suitable for non-experts as an introduction into this exciting research area. Contents:Cryo-Electron Microscopy of Viruses (N A Ranson & P G Stockley)What Does It Take to Make a Virus: The Concept of the Viral “Self” (N G A Abrescia et al.)Beyond Quasi-Equivalence: New Insights Into Viral Architecture via Affine Extended Symmetry Groups (T Keef & R Twarock)Mechanical Properties of Viruses (W H Roos & G J L Wuite)Investigating Viral Structure, Function and Dynamics with Mass Spectrometry (E B Monroe & P E Prevelige)An Overview of Capsid Assembly Kinetics (J Z Porterfield & A Zlotnick)Assembly and Disassembly of Deltahedral Viral Shells (A Yu Morozov et al.)What Determines the Size of an RNA Virus? (C M Knobler & W M Gelbart)Physics of Viral Infectivity: Matching Genome Length with Capsid Size (A Evilevitch & M Castelnovo)Topology of Viral DNA (J Arsuaga et al.)The Use of Viruses in Biomedical Nanotechnology (K J Koudelka & M Manchester) Readership: Biologists, biophysicists, chemists, clinicians and mathematical biologists interested in virus structure, function and dynamics. Keywords:Virology;Modeling;Virus Assembly;Virus Structure;Genome Organisation;Cryo-Electron Microscopy;Mass Spectrometry;Viral Evolution