Biophysics Of Molecular Chaperones
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Biophysics Of Molecular Chaperones
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Author : Sebastian Hiller
language : en
Publisher: Royal Society of Chemistry
Release Date : 2023-11-01
Biophysics Of Molecular Chaperones written by Sebastian Hiller and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-01 with Science categories.
Molecular Chaperones
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Author : R.J. Ellis
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Molecular Chaperones written by R.J. Ellis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Currently one of the hottest topics in biochemistry, the concept of molecular chaperones has challenged the paradigm of protein self-assembly. Key figures in many disciplines review all aspects of molecular chaperones in this volume, which arises from a Royal Society discussion meeting. Overview chapters discuss the significance of chaperones in biochemistry, molecular genetics and cell biology. Each chapter is well referenced providing access to the literature.
Molecular Chaperones
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Author : Sophie Jackson
language : en
Publisher: Springer
Release Date : 2012-12-15
Molecular Chaperones written by Sophie Jackson and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-15 with Science categories.
Assisting Oxidative Protein Folding: How Do Protein Disulphide-Isomerases Couple Conformational and Chemical Processes in Protein Folding?, by A. Katrine Wallis and Robert B. Freedman Peptide Bond cis/trans Isomerases: A Biocatalysis Perspective of Conformational Dynamics in Proteins, by Cordelia Schiene-Fischer, Tobias Aumüller and Gunter Fischer Small Heat-Shock Proteins: Paramedics of the Cell, by Gillian R. Hilton, Hadi Lioe, Florian Stengel, Andrew J. Baldwin und Justin L. P. Benesch Allostery in the Hsp70 Chaperone Proteins, by Erik R. P. Zuiderweg, Eric B. Bertelsen, Aikaterini Rousaki, Matthias P. Mayer, Jason E. Gestwicki and Atta Ahmad Hsp90: Structure and Function, by Sophie E. Jackson Extracellular Chaperones, by Rebecca A. Dabbs, Amy R. Wyatt, Justin J. Yerbury, Heath Ecroyd and Mark R. Wilson
Molecular Chaperones
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Author : Stuart K. Calderwood
language : en
Publisher: Humana Press
Release Date : 2011-09-07
Molecular Chaperones written by Stuart K. Calderwood and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-07 with Science categories.
The proteome consists of a complex mixture of proteins each of which need to be folded correctly in order to function for the health of the organism, and many of these proteins require molecular chaperones to reach the correct conformation and, in some cases, to remain in a folded form. In Molecular Chaperones: Methods and Protocols, expert researchers address a wide variety of approaches to the study these mechanisms, featuring the workings of heat shock proteins and heat shock transcription factors, in vitro and in vivo. Written in the highly successful Methods in Molecular BiologyTM series format, chapters features introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Molecular Chaperones: Methods and Protocols serves as an ideal guide for all scientists who wish to pursue this vital biological action and its impact on human health and disease.
Prokaryotic Chaperonins
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Author : C. M. Santosh Kumar
language : en
Publisher: Springer
Release Date : 2017-08-30
Prokaryotic Chaperonins written by C. M. Santosh Kumar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-30 with Science categories.
This book focuses on a topical and timely aspect of prokaryotic biology - the biology of prokaryotic multiple chaperonins. Chaperonins are a class of molecular chaperones, the proteins that assist folding of other proteins in the cell. The book begins with an introductory chapter on the structural and functional aspects of chaperonins, followed by an outline on different mechanisms of their regulation. Subsequently, the book provides a comprehensive overview on how the multiple-chaperonins have embraced biological requirements in different classes of microbes, discussing their functional diversity, evolutionary paths and the latest advances in the field. It brings together leading experts from across the globe in offering a detailed account of the structural, biochemical, functional and phylogenetic characteristics of microbial chaperonins for students, researchers and teachers working in the area of microbiology/ biophysics/ parasitology – more specifically, in protein folding pathways.
Molecular Chaperones
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Author : G.H. Lorimer
language : en
Publisher:
Release Date : 1998
Molecular Chaperones written by G.H. Lorimer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with categories.
The Molecular Chaperones Interaction Networks In Protein Folding And Degradation
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Author : Walid A. Houry
language : en
Publisher: Springer
Release Date : 2014-09-01
The Molecular Chaperones Interaction Networks In Protein Folding And Degradation written by Walid A. Houry and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-01 with Science categories.
Molecular chaperones are a fundamental group of proteins that have been identified only relatively recently. They are key components of a protein quality machinery in the cell which insures that the folding process of any newly-synthesized polypeptide chain results in the formation of a properly folded protein and that the folded protein is maintained in an active conformation throughout its functional lifetime. Molecular chaperones have been shown to play essential roles in cell viability under both normal and stress conditions. Chaperones can also assist in the unfolding and degradation of misfolded proteins and in disaggregating preformed protein aggregates. Chaperones are also involved in other cellular functions including protein translocation across membranes, vesicle fusion events, and protein secretion. In recent years, tremendous advances have been made in our understanding of the biology, biochemistry, and biophysics of function of molecular chaperones. In addition, recent technical developments in the fields of proteomics and genomics allowed us to obtain a global view of chaperone interaction networks. Finally, there is now a growing interest in the role of molecular chaperones in diseases. This book will provide a comprehensive analysis of the structure and function of the diverse systems of molecular chaperones and their role in cell stress responses and in diseases from a global network perspective.
Chaperones
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Author : Stuart K. Calderwood
language : en
Publisher: Springer Nature
Release Date : 2023-08-04
Chaperones written by Stuart K. Calderwood and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-04 with Science categories.
This second edition volume expands on the previous edition with new discussions on the latest techniques used to study molecular chaperones and the stress response. The chapters in this book cover such as analysis of the initiation and regulation of the stress response; the role of heat shock protein 90 (Hsp90) in gene expression through chromosome-immunoprecipitation; features of chaperone function and biology; the emerging role of the extracellular HSPs; and the use of chaperones as biomarkers. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Chaperones: Methods and Protocols, Second Edition is a valuable resource for all researchers who want to learn more about this interesting and developing field.
Molecular Chaperones In Health And Disease
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Author : Matthias Gaestel
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-09-27
Molecular Chaperones In Health And Disease written by Matthias Gaestel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-09-27 with Science categories.
Molecular chaperones are involved in a wide variety of essential cellular processes in living cells. A subset of molecular chaperones have been initially described as heat shock proteins protecting cells from stress damage by keeping cellular proteins in a folding competent state and preventing them from irreversible aggregation. Later it became obvious that molecular chaperones are also expressed constitutively in the cell and are involved in complex processes such as protein synthesis, intracellular protein transport, post-translational modification and secretion of proteins as well as receptor signalling. Hence, it is not surprising that molecular chaperones are implicated in the pathogenesis of many relevant diseases and could be regarded as potential pharmacological targets. Starting with the analysis of the mode of action of chaperones at the molecular, cellular and organismic level, this book will then describe specific aspects where modulation of chaperone action could be of pharmacological and therapeutic interest.
Molecular Aspects Of The Stress Response Chaperones Membranes And Networks
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Author : Peter Csermely
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-08-09
Molecular Aspects Of The Stress Response Chaperones Membranes And Networks written by Peter Csermely and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-09 with Science categories.
This book makes a novel synthesis of the molecular aspects of the stress response and long term adaptation processes with the system biology approach of biological networks. Authored by an exciting mixture of top experts and young rising stars, it provides a comprehensive summary of the field and identifies future trends.