Bioreaction Engineering Bioprocess Monitoring
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Bioreaction Engineering Bioprocess Monitoring
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Author : Karl Schügerl
language : en
Publisher: John Wiley & Sons
Release Date : 1997-04-03
Bioreaction Engineering Bioprocess Monitoring written by Karl Schügerl and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-04-03 with Science categories.
Volume 3 of Bioreaction Engineering covers the general principles and techniques of bioprocess monitoring and their application for various bioprocesses. Methods based on the author's long standing experience working with various bioprocesses are applied within the book. In particular, the cultivation of Baker's yeast; production of fusion protein with recombinant E. Coli, alkaline serine protease production with Bacillus licheniformis; production of penicillin V with Penicillin chrysogenum; Cephalosporin C with Acremonium chrysogenum and tetracycline with Streptomyces aureofaciens are considered. This book deals with the monitoring of batch and perfusion cultivations of animal cells and production of monoclonal antibodies with hybridoma cells, Antithrombin III with BHK and CHO cells and ß -galactosidase with insect cells. The topics covered include: Bioprocess monitoring techniques Cultivation of Saccharomyces cerevisiae Production of Fusion Protein with Recombinanat E. coli Alkaline Protease Production with Bacillus licheniformis Antibiotica Production by Fungi and Streptomycetes Continuous Production of Primary Metabolites with Suspended and Immobilized Microorganisms Cultivation of Animal Cells and Production of Proteins Anaerobic Waste Water Treatment Fast Process Monitoring Techniques Image Analysis of Cells and Cell Aggregates Evaluation of Experimental Data to the Calculation of Metabolite Flux in Microorganisms and Animal Cells Signal Evaluation, Automation and Expert Systems for Process Monitoring Bioprocess Monitoring is invaluable for process engineers, analytical chemists and researchers in biotechnological, pharmaceutical, environmnental and chemical industries.
Bioreaction Engineering Fundamentals Thermodynamics Formal Kinetics Idealized Reactor Types And Operation Modes
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Author : Karl Schügerl
language : en
Publisher: Wiley
Release Date : 1987-10-27
Bioreaction Engineering Fundamentals Thermodynamics Formal Kinetics Idealized Reactor Types And Operation Modes written by Karl Schügerl and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987-10-27 with Technology & Engineering categories.
Bioreaction Engineering Reactions Involving Microorganisms and Cells Volume 1 Fundamentals, Thermodynamics, Formal kinetics, Idealized reactor types and Operation modes Karl Schügerl, Professor of Technical Chemistry, Institut für Technische Chemie, Universität Hannover, West Germany This book is designed to provide a basic introduction to the principles of bioreactors, their operating parameters, and their dynamic behaviour under different conditions. The following topics are covered: Introduction Principles Modus operandi of bioreactors Idealized types Formal kinetics of cell growth and product formation in idealized reactors Operation modes in stirred reactors The book will be valuable to both process and control engineers in the fermentation industry and to researchers and lecturers in biotechnology departments of universities.
Bioreaction Engineering Principles
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Author : Jens Nielsen
language : en
Publisher: Springer
Release Date : 2012-12-06
Bioreaction Engineering Principles written by Jens Nielsen and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Technology & Engineering categories.
This is the second edition of the text "Bioreaction Engineering Principles" by Jens Nielsen and John Villadsen, originally published in 1994 by Plenum Press (now part of Kluwer). Time runs fast in Biotechnology, and when Kluwer Plenum stopped reprinting the first edition and asked us to make a second, revised edition we happily accepted. A text on bioreactions written in the early 1990's will not reflect the enormous development of experimental as well as theoretical aspects of cellular reactions during the past decade. In the preface to the first edition we admitted to be newcomers in the field. One of us (JV) has had 10 more years of job training in biotechnology, and the younger author (IN) has now received international recognition for his work with the hottest topics of "modem" biotechnology. Furthermore we are happy to have induced Gunnar Liden, professor of chemical reaction engineering at our sister university in Lund, Sweden to join us as co-author of the second edition. His contribution, especially on the chemical engineering aspects of "real" bioreactors has been of the greatest value. Chapter 8 of the present edition is largely unchanged from the first edition. We wish to thank professor Martin Hjortso from LSU for his substantial help with this chapter.
Bioprocessing Technology For Production Of Biopharmaceuticals And Bioproducts
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Author : Claire Komives
language : en
Publisher: John Wiley & Sons
Release Date : 2018-12-27
Bioprocessing Technology For Production Of Biopharmaceuticals And Bioproducts written by Claire Komives and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-27 with Science categories.
Written for industrial and academic researchers and development scientists in the life sciences industry, Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts is a guide to the tools, approaches, and useful developments in bioprocessing. This important guide: • Summarizes state-of-the-art bioprocessing methods and reviews applications in life science industries • Includes illustrative case studies that review six milestone bio-products • Discuses a wide selection of host strain types and disruptive bioprocess technologies
Bioprocess Engineering Principles
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Author : Pauline M. Doran
language : en
Publisher: Elsevier
Release Date : 1995-04-03
Bioprocess Engineering Principles written by Pauline M. Doran and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-04-03 with Science categories.
The emergence and refinement of techniques in molecular biology has changed our perceptions of medicine, agriculture and environmental management. Scientific breakthroughs in gene expression, protein engineering and cell fusion are being translated by a strengthening biotechnology industry into revolutionary new products and services. Many a student has been enticed by the promise of biotechnology and the excitement of being near the cutting edge of scientific advancement. However, graduates trained in molecular biology and cell manipulation soon realise that these techniques are only part of the picture. Reaping the full benefits of biotechnology requires manufacturing capability involving the large-scale processing of biological material. Increasingly, biotechnologists are being employed by companies to work in co-operation with chemical engineers to achieve pragmatic commercial goals. For many years aspects of biochemistry and molecular genetics have been included in chemical engineering curricula, yet there has been little attempt until recently to teach aspects of engineering applicable to process design to biotechnologists.This textbook is the first to present the principles of bioprocess engineering in a way that is accessible to biological scientists. Other texts on bioprocess engineering currently available assume that the reader already has engineering training. On the other hand, chemical engineering textbooks do not consider examples from bioprocessing, and are written almost exclusively with the petroleum and chemical industries in mind. This publication explains process analysis from an engineering point of view, but refers exclusively to the treatment of biological systems. Over 170 problems and worked examples encompass a wide range of applications, including recombinant cells, plant and animal cell cultures, immobilised catalysts as well as traditional fermentation systems.* * First book to present the principles of bioprocess engineering in a way that is accessible to biological scientists* Explains process analysis from an engineering point of view, but uses worked examples relating to biological systems* Comprehensive, single-authored* 170 problems and worked examples encompass a wide range of applications, involving recombinant plant and animal cell cultures, immobilized catalysts, and traditional fermentation systems* 13 chapters, organized according to engineering sub-disciplines, are groupled in four sections - Introduction, Material and Energy Balances, Physical Processes, and Reactions and Reactors* Each chapter includes a set of problems and exercises for the student, key references, and a list of suggestions for further reading* Includes useful appendices, detailing conversion factors, physical and chemical property data, steam tables, mathematical rules, and a list of symbols used* Suitable for course adoption - follows closely curricula used on most bioprocessing and process biotechnology courses at senior undergraduate and graduate levels.
Bioreactors
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Author : Goutam Saha
language : en
Publisher: CRC Press
Release Date : 2017-12-01
Bioreactors written by Goutam Saha and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-01 with Medical categories.
Bioreactors: Animal Cell Culture Control for Bioprocess Engineering presents the design, fabrication, and control of a new type of bioreactor meant especially for animal cell line culture. The new bioreactor, called the "see-saw bioreactor," is ideal for the growth of cells with a sensitive membrane. The see-saw bioreactor derives its name from its principle of operation in which liquid columns in either limb of the reactor alternately go up and down. The working volume of the reactor is small, to within 15 L. However, it can easily be scaled up for large production in volume of cell mass in the drug and pharmaceutical industries. The authors describe the principle of operation of the see-saw bioreactor and how to automatically control the bioprocess. They discuss different control strategies as well as the thorough experimental research they conducted on this prototype bioreactor in which they applied a time delay control for yield maximization. To give you a complete understanding of the design and development of the see-saw bioreactor, the authors cover the mathematical model they use to describe the kinetics of fermentation, the genetic algorithms used for deriving the optimal time trajectories of the bioprocess variables, and the corresponding control inputs for maximizing the product yield. One chapter is devoted to the application of time delay control. Following a description of the bioreactor’s working setup in the laboratory, the authors sum up their investigation and define the future scope of work in terms of design, control, and software sensors.
Bioreactors
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Author : Carl-Fredrik Mandenius
language : en
Publisher: John Wiley & Sons
Release Date : 2016-02-16
Bioreactors written by Carl-Fredrik Mandenius and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-16 with Science categories.
In this expert handbook both the topics and contributors are selected so as to provide an authoritative view of possible applications for this new technology. The result is an up-to-date survey of current challenges and opportunities in the design and operation of bioreactors for high-value products in the biomedical and chemical industries. Combining theory and practice, the authors explain such leading-edge technologies as single-use bioreactors, bioreactor simulators, and soft sensor monitoring, and discuss novel applications, such as stem cell production, process development, and multi-product reactors, using case studies from academia as well as from industry. A final section addresses the latest trends, including culture media design and systems biotechnology, which are expected to have an increasing impact on bioreactor design. With its focus on cutting-edge technologies and discussions of future developments, this handbook will remain an invaluable reference for many years to come.
Bioprocess Engineering Principles
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Author : Pauline M. Doran
language : en
Publisher: Academic Press
Release Date : 2013
Bioprocess Engineering Principles written by Pauline M. Doran and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Science categories.
The emergence and refinement of techniques in molecular biology has changed our perceptions of medicine, agriculture, and environmental management. This textbook presents the principles of bioprocess engineering in a way that is accessible to biological scientists.
Bioreactor Engineering Research And Industrial Applications Ii
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Author : Jie Bao
language : en
Publisher: Springer
Release Date : 2015-11-26
Bioreactor Engineering Research And Industrial Applications Ii written by Jie Bao and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-26 with Science categories.
This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.
Bioprocess Engineering
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Author : Shijie Liu
language : en
Publisher: Newnes
Release Date : 2012-11-07
Bioprocess Engineering written by Shijie Liu and has been published by Newnes this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-07 with Science categories.
Bioprocess Engineering involves the design and development of equipment and processes for the manufacturing of products such as food, feed, pharmaceuticals, nutraceuticals, chemicals, and polymers and paper from biological materials. It also deals with studying various biotechnological processes. "Bioprocess Kinetics and Systems Engineering" first of its kind contains systematic and comprehensive content on bioprocess kinetics, bioprocess systems, sustainability and reaction engineering. Dr. Shijie Liu reviews the relevant fundamentals of chemical kinetics-including batch and continuous reactors, biochemistry, microbiology, molecular biology, reaction engineering, and bioprocess systems engineering- introducing key principles that enable bioprocess engineers to engage in the analysis, optimization, design and consistent control over biological and chemical transformations. The quantitative treatment of bioprocesses is the central theme of this book, while more advanced techniques and applications are covered with some depth. Many theoretical derivations and simplifications are used to demonstrate how empirical kinetic models are applicable to complicated bioprocess systems. Contains extensive illustrative drawings which make the understanding of the subject easy Contains worked examples of the various process parameters, their significance and their specific practical use Provides the theory of bioprocess kinetics from simple concepts to complex metabolic pathways Incorporates sustainability concepts into the various bioprocesses