Bioreactor Design Concepts For Viral Vaccine Production

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Bioreactor Design Concepts For Viral Vaccine Production
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Author : Surajbhan Sevda
language : en
Publisher: Elsevier
Release Date : 2024-05-12
Bioreactor Design Concepts For Viral Vaccine Production written by Surajbhan Sevda and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-12 with Science categories.
Bioreactor Design Concepts for Viral Vaccine Production covers a range of interdisciplinary chapters from the engineering perspective of bioreactor design to the biotechnological perspectives of vector design for vaccine development. The book covers bioreactor concepts such as static systems, single-use systems, stirred tanks, perfusion, wave and packed-beds. It reviews options for efficient and economical production of human vaccines and discusses basic factors relevant for viral antigen production in mammalian cells, avian cells, and insect cells. This book will be a great resource for those interested in implemented novel bioreactor design or experimental schemes towards intensified or/and enhanced vaccine production. - Covers the fundamentals of bioreactor designs - Provides strategies for designing a successful vector-based vaccine - Discusses the applications of biological kinetics, thermodynamics and basic substrate requirements for viral vaccine production
Application Of Bio Additives For The Food Industry
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Author : Abdul Sattar Jatoi
language : en
Publisher: Springer Nature
Release Date : 2024-11-21
Application Of Bio Additives For The Food Industry written by Abdul Sattar Jatoi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-21 with Technology & Engineering categories.
This text provides advanced and comprehensive information related to food additives based on bio-sources. A thorough overview of the many groups of microorganisms used as food additives is presented, as well as all of their main characteristics. The chapters give a step-by-step description of bio based food additives, including substances that are employed commercially by manufacturers as enzymes, antioxidants, stabilizers, emulsifiers, organic acids, colorants, sweeteners, and flavorings. Additionally, each chapter places a focus on the usage of probiotics and enzymes as examples of microbes used as medicinal agents. In its examination of the food additive lists for food products for the manufacture of nourishing and safe food, Application of Bio-Additives for the Food Industry offers a thorough, updated overview of food bio-additives that can be utilized by food scientists, nutritionists, microbiologists and more.
Integrated Food And Bioprocessing
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Author : Abdul Sattar Jatoi
language : en
Publisher: Springer Nature
Release Date : 2025-05-26
Integrated Food And Bioprocessing written by Abdul Sattar Jatoi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-26 with Technology & Engineering categories.
In a rapidly evolving world, the integration of food processing and bioprocessing technologies has become essential to meet the demands of sustainable food production, resource optimization, and environmental conservation. This groundbreaking book, Integrated Food and Bioprocessing, provides a comprehensive overview of the principles, practices, and innovations shaping the future of these interconnected fields. Key Features Include: Foundations of Integration: A detailed introduction to food engineering and bioprocessing principles. Biotechnology in Action: Insights into fermentation, enzymatic processing, and microbial applications in food systems. Innovative Solutions: Cutting-edge advancements in food preservation, waste valorization, and energy-efficient technologies. Sustainability Focus: Strategies for implementing circular bioeconomy practices and reducing environmental impact. Real-World Applications: Case studies and practical examples from diverse industries. Designed for food scientists, biotechnologists, engineers, and students, this book bridges theory and practice, offering valuable tools for addressing global challenges in food security, resource management, and climate resilience. Whether you are an industry professional, researcher, or academic, Integrated Food and Bioprocessing serves as an indispensable guide to the transformative technologies at the forefront of food and bioprocessing innovation.
Bioprocessing Of Viral Vaccines
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Author : Amine Kamen
language : en
Publisher: CRC Press
Release Date : 2022-09-06
Bioprocessing Of Viral Vaccines written by Amine Kamen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-06 with Medical categories.
This book focuses on cell culture-produced viral vaccines to meet the needs of the rapidly expanding research and development in academia and industry in the field. This book introduces the basic principles of vaccination and the manufacturing of viral vaccines. Bioprocessing of Viral Vaccines, will provide an overview of the advanced strategies needed to respond to the challenges of new and established viral infection diseases. The first few chapters cover the basics of virology and immunology as essential concepts to understand the function and design of viral vaccines. The core of the content is dedicated to process development, including upstream processing and cell culture of viral vaccines, downstream processing, and extensive analytical technologies specific to viral vaccines. Advanced process analytical technologies (PAT) and Quality by Design (QbD) concepts are also introduced in the context of vaccine manufacturing. The case studies included cover inactivated, attenuated vaccines exemplified by influenza vaccines, sub-unit vaccines exemplified by Virus Like Particles (VLPs: HPV vaccines) and sub-unit vaccines (Flublock), vectored vaccines: adenoviruses and Vesicular stomatitis Virus (VSV) vectored vaccines, genomic vaccines (DNA and mRNA) vaccines as developed for COVID-19 response in particular and a review of COVID-19 vaccines approved or in advanced clinical trials. This book is aimed at graduate engineers and professionals in the fields of vaccinology, bioprocessing, and biomanufacturing of viral vaccines.
Bioprocess And Analytics Development For Virus Based Advanced Therapeutics And Medicinal Products Atmps
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Author : Saurabh Gautam
language : en
Publisher: Springer Nature
Release Date : 2023-08-10
Bioprocess And Analytics Development For Virus Based Advanced Therapeutics And Medicinal Products Atmps written by Saurabh Gautam and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-10 with Medical categories.
This book reviews the knowledge, methods and available techniques in the rapidly advancing field of virus based vaccines and gene therapeutics. It also highlights new innovative tools and interdisciplinary techniques for bioprocess development and analytics of viruses and viral vectors. As such, it provides a timely and highly relevant resource, since current advances in pharmaceutical research have seen the rise of vaccines and advanced therapeutics and medicinal products (ATMPs), that rely on the power of viruses. However, developing bioprocesses and analytics required to create this often called “magic bullet” (i.e. gene therapy) remains an extremely challenging and costly task. This book offers strategies for overcoming hurdles and difficulties within in all the necessary steps of viral vector development - from scalability to purification methods and quality control. The book is intended for researchers working in academia or industry, as well as graduate students pursuing a career in virology.
Nanoscale Fabrication Optimization Scale Up And Biological Aspects Of Pharmaceutical Nanotechnology
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Author : Alexandru Mihai Grumezescu
language : en
Publisher: William Andrew
Release Date : 2017-12-11
Nanoscale Fabrication Optimization Scale Up And Biological Aspects Of Pharmaceutical Nanotechnology written by Alexandru Mihai Grumezescu and has been published by William Andrew this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-11 with Science categories.
Nanoscale Fabrication, Optimization, Scale-up and Biological Aspects of Pharmaceutical Nanotechnology focuses on the fabrication, optimization, scale-up and biological aspects of pharmaceutical nanotechnology. In particular, the following aspects of nanoparticle preparation methods are discussed: the need for less toxic reagents, simplification of the procedure to allow economic scale-up, and optimization to improve yield and entrapment efficiency. Written by a diverse range of international researchers, the chapters examine characterization and manufacturing of nanomaterials for pharmaceutical applications. Regulatory and policy aspects are also discussed. This book is a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about how nanomaterials can best be utilized. - Shows how nanomanufacturing techniques can help to create more effective, cheaper pharmaceutical products - Explores how nanofabrication techniques developed in the lab have been translated to commercial applications in recent years - Explains safety and regulatory aspects of the use of nanomanufacturing processes in the pharmaceutical industry
Single Use Technology In Biopharmaceutical Manufacture
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Author : Regine Eibl
language : en
Publisher: John Wiley & Sons
Release Date : 2019-07-18
Single Use Technology In Biopharmaceutical Manufacture written by Regine Eibl and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-18 with Medical categories.
Authoritative guide to the principles, characteristics, engineering aspects, economics, and applications of disposables in the manufacture of biopharmaceuticals The revised and updated second edition of Single-Use Technology in Biopharmaceutical Manufacture offers a comprehensive examination of the most-commonly used disposables in the manufacture of biopharmaceuticals. The authors—noted experts on the topic—provide the essential information on the principles, characteristics, engineering aspects, economics, and applications. This authoritative guide contains the basic knowledge and information about disposable equipment. The author also discusses biopharmaceuticals’ applications through the lens of case studies that clearly illustrate the role of manufacturing, quality assurance, and environmental influences. This updated second edition revises existing information with recent developments that have taken place since the first edition was published. The book also presents the latest advances in the field of single-use technology and explores topics including applying single-use devices for microorganisms, human mesenchymal stem cells, and T-cells. This important book: • Contains an updated and end-to-end view of the development and manufacturing of single-use biologics • Helps in the identification of appropriate disposables and relevant vendors • Offers illustrative case studies that examine manufacturing, quality assurance, and environmental influences • Includes updated coverage on cross-functional/transversal dependencies, significant improvements made by suppliers, and the successful application of the single-use technologies Written for biopharmaceutical manufacturers, process developers, and biological and chemical engineers, Single-Use Technology in Biopharmaceutical Manufacture, 2nd Edition provides the information needed for professionals to come to an easier decision for or against disposable alternatives and to choose the appropriate system.
Animal Stem Cells
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Author : Amita Sarkar
language : en
Publisher: Discovery Publishing House
Release Date : 2009
Animal Stem Cells written by Amita Sarkar and has been published by Discovery Publishing House this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Physiology categories.
Cell Culture Technology For Pharmaceutical And Cell Based Therapies
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Author : Sadettin Ozturk
language : en
Publisher: CRC Press
Release Date : 2005-08-30
Cell Culture Technology For Pharmaceutical And Cell Based Therapies written by Sadettin Ozturk and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-08-30 with Medical categories.
Edited by two of the most distinguished pioneers in genetic manipulation and bioprocess technology, this bestselling reference presents a comprehensive overview of current cell culture technology used in the pharmaceutical industry. Contributions from several leading researchers showcase the importance of gene discovery and genomic technology devel
In Vitro Production Of Plant Secondary Metabolites
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Author : M. Anuradha
language : en
Publisher: Springer Nature
Release Date : 2025-03-21
In Vitro Production Of Plant Secondary Metabolites written by M. Anuradha and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-21 with Science categories.
This book addresses the literature gap by providing both theoretical foundations and practical insights into in vitro plant secondary metabolite production. It emphasizes the urgency to address the strategies and scientific methods for producing the secondary metabolites in the laboratory conditions. This book includes chapters on various in vitro strategies and laboratory methods, which are crucial for understanding and implementing techniques in this applied field. It equips the readers with the knowledge essential for contributions to pharmaceuticals, agriculture and various industries, thus filling a critical void currently present in the literature and practical applications in this field. This book is structured to cater to a diverse audience, including graduate students and researchers. It is specifically tailored to address the key aspects of plant cell, tissue and organ culture, and aligns seamlessly with the curriculum requirements for the courses offered in plant biotechnology. The modules on cell cultures, secondary metabolite production, and metabolic engineering are also integral components for these courses.