Bioreactors Process And Analysis
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Bioreactors Process And Analysis
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Author : Tapobrata Panda
language : en
Publisher: Tata McGraw-Hill Education
Release Date : 2011
Bioreactors Process And Analysis written by Tapobrata Panda and has been published by Tata McGraw-Hill Education this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Bioreactors categories.
6. Bioreactor modeling -- Model - what is it? -- Definition of lumped and distributed parameter models -- Introduction to a few terminologies and theorems -- Modeling principles -- Steps in modeling -- Fundamental laws used in process modeling -- First-order systems -- Second-order systems -- Complexity of the model -- Parameter sensitivity -- Exercises -- References -- Appendix 6 -- 7. Transport processes in bioreactors -- Introduction -- Heat transfer -- Other parameters influencing transfer operations -- Exercises -- References -- 8. Controls in bioreactors -- Introduction -- Control tasks in a bioreactor system -- Instrumentation to control a bioreactor -- Controlled variables and measurement devices -- Procedure for design of efficient control systems -- Conventional control techniques -- Advanced control techniques -- Consistency checks on measurements -- Adaptive online optimizing control of bioreactor system -- Exercises -- References -- Appendix 8 -- 9. Case studies -- Introduction -- Design of packed bed bioreactor -- Airlift bioreactors -- Hollow fiber bioreactor (HFBR) -- Plant cell bioreactor -- Design of bioreactors for solid state fermentation (SSF) -- Mammalian cell bioreactor design -- Exercises -- References -- Appendix 9 -- 10. Application of computational fluid dynamics in bioreactor analysis and design -- Introduction -- Fluid dynamic modeling -- Simulation -- Exercises -- References -- Appendix 10 -- 11. Scale-up of bioreactors -- Introduction -- Additional scale-up problems in bioreactors -- Criteria of scale-up -- Similarity criteria -- Scale-up methods -- Generalized approaches to scale-up in combination of methods -- Examples -- Exercises -- References -- 12. Mechanical aspects of bioreactor design -- Introduction -- Requirements for construction of a bioreactor -- Guidelines for bioreactor design -- Bioreactor vessels -- Agitator assembly -- Exercises -- References -- Appendix 12
New Directions In Bioprocess Modeling And Control
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Author : Michael A. Boudreau
language : en
Publisher: ISA
Release Date : 2007
New Directions In Bioprocess Modeling And Control written by Michael A. Boudreau and has been published by ISA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Science categories.
Models offer benefits even before they are put on line. Based on years of experience, the authors reveal in New Directions in Bioprocess Modeling and Control that significant improvements can result from the process knowledge and insight that are gained when building experimental and first-principle models for process monitoring and control. Doing modeling in the process development and early commercialization phases is advantageous because it increases process efficiency and provides ongoing opportunities for improving process control. This technology is important for maximizing benefits from analyzers and control tool investments. If you are a process design, quality control, information systems, or automation engineer in the biopharmaceutical, brewing, or bio-fuel industry, this handy resource will help you define, develop, and apply a virtual plant, model predictive control, first-principle models, neural networks, and multivariate statistical process control. The synergistic knowledge discovery on bench top or pilot plant scale can be ported to industrial scale processes. This learning process is consistent with the intent in the Process Analyzer and Process Control Tools sections of the FDA_s Guidance for Industry PAT _ A Framework for Innovative Pharmaceutical Development, Manufacturing and Quality Assurance. It states in the Process Analyzer section of the FDA_s guidance: _For certain applications, sensor-based measurements can provide a useful process signature that may be related to the underlying process steps or transformations. Based on the level of process understanding these signatures may also be useful for the process monitoring, control, and end point determination when these patterns or signatures relate to product and process quality._
Disposable Bioreactors Ii
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Author : Dieter Eibl
language : en
Publisher: Springer
Release Date : 2013-12-17
Disposable Bioreactors Ii written by Dieter Eibl and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-17 with Science categories.
Dynamic Single-Use Bioreactors Used in Modern Liter- and m3- Scale Biotechnological Processes: Engineering Characteristics and Scaling Up, by Christian Löffelholz, Stephan C. Kaiser, Matthias Kraume, Regine Eibl , Dieter Eibl. Orbitally Shaken Single-Use Bioreactors, by Wolf Klöckner, Sylvia Diederichs, Jochen Büchs. Therapeutic Human Cells: Manufacture for Cell Therapy/Regenerative Medicine by Christian van den Bos, Robert Keefe, Carmen Schirmaier, Michael McCaman. Fast Single-Use VLP Vaccine Productions Based on Insect Cells and the Baculovirus Expression Vector System: Influenza as Case Study by Regine Eibl, Nina Steiger, Sabine Wellnitz, Tiago Vicente, Corinne John, Dieter Eibl. Microbial High Cell Density Fermentations in a Stirred Single-Use Bioreactor by Thomas Dreher, Bart Walcarius, Ute Husemann, Franziska Klingenberg, Christian Zahnow, Thorsten Adams, Davy de Wilde, Peter Casteels, Gerhard Greller. Quorus Bioreactor: A New Perfusion-Based Technology for Microbial Cultivation by Sheena J. Fraser, Christian Endres. Cultivation of Marine Microorganisms in Single-Use Systems by Friederike Hillig, Maciej Pilarek, Stefan Junne, Peter Neubauer. Flexible Biomanufacturing Processes that Address the Needs of the Future by Bernhard Diel, Christian Manzke, Thorsten Peuker. An Approach to Quality and Security of Supply for Single-Use Bioreactors by Magali Barbaroux, Susanne Gerighausen, Heiko Hackel. A Risk Analysis for Production Processes with Disposable Bioreactors by Tobias Merseburger, Ina Pahl, Daniel Müller, Markus Tanner.
Bioreactors
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Author : Tapobrata Panda
language : en
Publisher:
Release Date :
Bioreactors written by Tapobrata Panda and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with Bioreactors categories.
Multiphase Bioreactor Design
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Author : Joaquim M.S. Cabral
language : en
Publisher: CRC Press
Release Date : 2001-09-20
Multiphase Bioreactor Design written by Joaquim M.S. Cabral and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-09-20 with Science categories.
Bioreaction engineering is fundamental to the optimization of biotechnological processes and the production of biochemicals by enzymes, microbial, plant and animal cells and higher organisms. A reference text for postgraduate students and researchers in biochemical engineering and bioreactor design, Multiphase Bioreactor Design describes the
Biotransformations And Bioprocesses
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Author : Mukesh Doble
language : en
Publisher: CRC Press
Release Date : 2004-03-24
Biotransformations And Bioprocesses written by Mukesh Doble and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-03-24 with Medical categories.
From the laboratory to full-scale commercial production, this reference provides a clear and in-depth analysis of bioreactor design and operation and encompasses critical aspects of the biocatalytic manufacturing process. It clarifies principles in reaction and biochemical engineering, synthetic and biotransformation chemistry, and biocell and enzy
Control In Bioprocessing
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Author : Pablo A. López Pérez
language : en
Publisher: John Wiley & Sons
Release Date : 2020-03-10
Control In Bioprocessing written by Pablo A. López Pérez and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-10 with Technology & Engineering categories.
Closes the gap between bioscience and mathematics-based process engineering This book presents the most commonly employed approaches in the control of bioprocesses. It discusses the role that control theory plays in understanding the mechanisms of cellular and metabolic processes, and presents key results in various fields such as dynamic modeling, dynamic properties of bioprocess models, software sensors designed for the online estimation of parameters and state variables, and control and supervision of bioprocesses Control in Bioengineering and Bioprocessing: Modeling, Estimation and the Use of Sensors is divided into three sections. Part I, Mathematical preliminaries and overview of the control and monitoring of bioprocess, provides a general overview of the control and monitoring of bioprocesses, and introduces the mathematical framework necessary for the analysis and characterization of bioprocess dynamics. Part II, Observability and control concepts, presents the observability concepts which form the basis of design online estimation algorithms (software sensor) for bioprocesses, and reviews controllability of these concepts, including automatic feedback control systems. Part III, Software sensors and observer-based control schemes for bioprocesses, features six application cases including dynamic behavior of 3-dimensional continuous bioreactors; observability analysis applied to 2D and 3D bioreactors with inhibitory and non-inhibitory models; and regulation of a continuously stirred bioreactor via modeling error compensation. Applicable across all areas of bioprocess engineering, including food and beverages, biofuels and renewable energy, pharmaceuticals and nutraceuticals, fermentation systems, product separation technologies, wastewater and solid-waste treatment technology, and bioremediation Provides a clear explanation of the mass-balance–based mathematical modelling of bioprocesses and the main tools for its dynamic analysis Offers industry-based applications on: myco-diesel for implementing "quality" of observability; developing a virtual sensor based on the Just-In-Time Model to monitor biological control systems; and virtual sensor design for state estimation in a photocatalytic bioreactor for hydrogen production Control in Bioengineering and Bioprocessing is intended as a foundational text for graduate level students in bioengineering, as well as a reference text for researchers, engineers, and other practitioners interested in the field of estimation and control of bioprocesses.
Bioreaction Analysis
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Author : Opubo G. Benebo
language : en
Publisher: Okumaye
Release Date : 2016-07-25
Bioreaction Analysis written by Opubo G. Benebo and has been published by Okumaye this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-25 with categories.
Bioreaction Analysis: Kinetics and Parameters of Bioreactions in Production Bioreactors, proffers structured methods for analyzing bio-reactions in production bioreactors in terms of the Cell-Biochemistry-based "Composited" Reactions Mass Action Kinetics; the new Bioreaction parameter, Mass and Thermal Diffusion Factors, (fD, fT), defined from the unique formulation of Diffusion Layers Analysis, explicitly reflecting the effects of Bioreaction engineering; and the unique Monod Model Kinetics: "Composited Reactions Monod Kinetics" derived by evaluating the Monod Equation constants using the Composited Mass Action Kinetics.Generalized solutions, as a collection of formulae, are developed, proffering computational practicalization of the design of Suspended Microbes Batch Microbiological Reactors, that should support most biological process businesses start-off, which begin operations with Batch Suspended Microbes Bioreactors, the same class of the reactor specifically adopted for developing the formulae including reaction kinetics data and rate equations, readily usable to perform the necessary computational analyses.Bioreaction Analysis: Kinetics and Parameters of Bioreactions in Production Bioreactors, therefore should be much useful to all professionals in the biotechnology industry; especially Bio-ventures Startups businesses and fermentors operators, and the production bioreactor engineer availed with generalized solutions for basic analysis of Bioreactors as to have the production process up and operating in no time.
Fundamentals Of Quorum Sensing Analytical Methods And Applications In Membrane Bioreactors
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Author :
language : en
Publisher: Elsevier
Release Date : 2018-05-21
Fundamentals Of Quorum Sensing Analytical Methods And Applications In Membrane Bioreactors written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-21 with Science categories.
Fundamentals of Quorum Sensing, Analytical Methods and Applications in Membrane Bioreactors, Volume 81, describes the novelty of membrane bioreactors for the treatment of wastewater and the removal of specific contaminants that affect water quality or pose harm to humans. Topics of note in the updated release include Water Chemistry and Microbiology, Quorum Sensing as Bacterial Communication Language, the Effects of Quorum Sensing, Quorum Quenching, Membrane Bioreactors for Wastewater Treatment, Removal of Specific Contaminants, Microextraction Techniques, and the Determination of Quorum Sensing Chemicals. The contents of this updated volume will be appealing to a wide range of researchers as the authors of most chapters are experts in their respective fields with numerous published studies. Gives an overview of quorum sensing as a communication language for bacteria and quorum quenching mediated approaches to mitigate or eliminate the effects of quorum sensing Presents various sensitive determination methods where a variety of microextraction strategies is used for preconcentration of analyte(s)
Bioreactors
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Author : Carl-Fredrik Mandenius
language : en
Publisher: John Wiley & Sons
Release Date : 2016-02-16
Bioreactors written by Carl-Fredrik Mandenius and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-16 with Science categories.
In this expert handbook both the topics and contributors are selected so as to provide an authoritative view of possible applications for this new technology. The result is an up-to-date survey of current challenges and opportunities in the design and operation of bioreactors for high-value products in the biomedical and chemical industries. Combining theory and practice, the authors explain such leading-edge technologies as single-use bioreactors, bioreactor simulators, and soft sensor monitoring, and discuss novel applications, such as stem cell production, process development, and multi-product reactors, using case studies from academia as well as from industry. A final section addresses the latest trends, including culture media design and systems biotechnology, which are expected to have an increasing impact on bioreactor design. With its focus on cutting-edge technologies and discussions of future developments, this handbook will remain an invaluable reference for many years to come.
