Biosimulation
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Biosimulation In Drug Development
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Author : Martin Bertau
language : en
Publisher: John Wiley & Sons
Release Date : 2008-09-08
Biosimulation In Drug Development written by Martin Bertau and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-08 with Medical categories.
This first comprehensive survey to cover all pharmaceutically relevant topics provides a comprehensive introduction to this novel and revolutionary tool, presenting both concepts and application examples of biosimulated cells, organs and organisms. Following an introduction to the role of biosimulation in drug development, the authors go on to discuss the simulation of cells and tissues, as well as simulating drug action and effect. A further section is devoted to simulating networks and populations, and the whole is rounded off by a look at the potential for biosimulation in industrial drug development and for regulatory decisions. Part of the authors are members of the BioSim Network of Excellence that encompasses more than 40 academic institutions, pharmaceutical companies and regulatory authorities dealing with drug development; other contributors come from industry, resulting in a cross-disciplinary expert reference.
Synthesis Of Biocomposite Materials
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Author : Yukio Imanishi
language : en
Publisher: CRC Press
Release Date : 2018-01-10
Synthesis Of Biocomposite Materials written by Yukio Imanishi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-10 with Science categories.
Biomaterials have been used for artificial-organ and bioreactor materials, and have gained importance for enhancement of human welfare. This book summarizes research devoted to creating useful biofunctional materials by chemical modification of natural polymers, and forecasts future development.
Annual Reports In Medicinal Chemistry
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Author : Annette M. Doherty
language : en
Publisher: Elsevier
Release Date : 2002-10-02
Annual Reports In Medicinal Chemistry written by Annette M. Doherty and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-10-02 with Medical categories.
Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.
In Silico Technologies In Drug Target Identification And Validation
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Author : Darryl Leon
language : en
Publisher: CRC Press
Release Date : 2006-06-13
In Silico Technologies In Drug Target Identification And Validation written by Darryl Leon and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-06-13 with Medical categories.
The pharmaceutical industry relies on numerous well-designed experiments involving high-throughput techniques and in silico approaches to analyze potential drug targets. These in silico methods are often predictive, yielding faster and less expensive analyses than traditional in vivo or in vitro procedures. In Silico Technologies in Drug Target Ide
Biotechnology Annual Review
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Author : M. Raafat El-Gewely
language : en
Publisher: Elsevier
Release Date : 2004-12-17
Biotechnology Annual Review written by M. Raafat El-Gewely and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-12-17 with Medical categories.
Biotechnology is a diverse, complex and rapidly evolving field. Students and experienced researchers alike face the challenges of staying on top of developments in their field of specialty and maintaining a broader overview of the field as a whole. Volumes containing competent reviews on a diverse range of topics in the field fulfill the dual role of broadening and updating biotechnologists knowledge. The current volume is an excellent example of such a book. The topics covered range from classical issues in biotechnology - such as, vehicles for the production of biotechnology products and methods for their detection, separation and analysis - to topics that are focused on the role of biotechnology in the health sciences. The information presented in this book will therefore will be of great value to both experienced biotechnologists and biotechnologists in training.
International Assessment Of Research And Development In Simulation Based Engineering And Science
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Author : Sharon C. Glotzer
language : en
Publisher: World Scientific
Release Date : 2011
International Assessment Of Research And Development In Simulation Based Engineering And Science written by Sharon C. Glotzer and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Computers categories.
Simulation-Based Engineering and Science (SBE&S) cuts across disciplines, showing tremendous promise in areas from storm prediction and climate modeling to understanding the brain and the behavior of numerous other complex systems. In this groundbreaking volume, nine distinguished leaders assess the latest research trends, as a result of 52 site visits in Europe and Asia and hundreds of hours of expert interviews, and discuss the implications of their findings for the US government. The authors conclude that while the US remains the quantitative leader in SBE&S research and development, it is very much in danger of losing that edge to Europe and Asia. Commissioned by the National Science Foundation, this multifaceted study will capture the attention of Fortune 500 companies and policymakers.
Nature
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Author : Sir Norman Lockyer
language : en
Publisher:
Release Date : 2008
Nature written by Sir Norman Lockyer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Electronic journals categories.
Biocomputing 2009
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Author : Russ B. Altman
language : en
Publisher: World Scientific
Release Date : 2008-11-28
Biocomputing 2009 written by Russ B. Altman and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-28 with Science categories.
The Pacific Symposium on Biocomputing (PSB) 2009 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2009 will be held on January 59, 2009 in Kamuela, Hawaii. Tutorials will be offered prior to the start of the conference. PSB 2009 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology. The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's "hot topics." In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.
Systems Biology In Drug Discovery And Development
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Author : Daniel L. Young
language : en
Publisher: John Wiley & Sons
Release Date : 2011-09-23
Systems Biology In Drug Discovery And Development written by Daniel L. Young and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-23 with Medical categories.
The first book to focus on comprehensive systems biology as applied to drug discovery and development Drawing on real-life examples, Systems Biology in Drug Discovery and Development presents practical applications of systems biology to the multiple phases of drug discovery and development. This book explains how the integration of knowledge from multiple sources, and the models that best represent that integration, inform the drug research processes that are most relevant to the pharmaceutical and biotechnology industries. The first book to focus on comprehensive systems biology and its applications in drug discovery and development, it offers comprehensive and multidisciplinary coverage of all phases of discovery and design, including target identification and validation, lead identification and optimization, and clinical trial design and execution, as well as the complementary systems approaches that make these processes more efficient. It also provides models for applying systems biology to pharmacokinetics, pharmacodynamics, and candidate biomarker identification. Introducing and explaining key methods and technical approaches to the use of comprehensive systems biology on drug development, the book addresses the challenges currently facing the pharmaceutical industry. As a result, it is essential reading for pharmaceutical and biotech scientists, pharmacologists, computational modelers, bioinformaticians, and graduate students in systems biology, pharmaceutical science, and other related fields.
Pharmaceutical Formulation Development Of Peptides And Proteins Second Edition
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Author : Lars Hovgaard
language : en
Publisher: CRC Press
Release Date : 2012-11-14
Pharmaceutical Formulation Development Of Peptides And Proteins Second Edition written by Lars Hovgaard and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-14 with Medical categories.
The rapid advances in recombinant DNA technology and the increasing availability of peptides and proteins with therapeutic potential are a challenge for pharmaceutical scientists who have to formulate these compounds as drug products. Pharmaceutical Formulation Development of Peptides and Proteins, Second Edition discusses the development of therapeutic peptides and proteins, from the production of active compounds via basic pre-formulation and formulation to the registration of the final product. Providing integrated solutions, this book discusses: The synthesis of peptides and the biotechnological production of proteins through recombinant DNA technology The physicochemical characteristics and stability of peptides and proteins The formulation of proteins as suspensions, solutions, and (mostly freeze-dried) solids The opportunities and challenges of non-parenteral delivery of peptides and proteins Risk factors, specifically the development of an unwanted immune response A simulation approach to describe the fate of peptides and proteins upon administration to a biological system The documentation required to register a protein-based drug Scientists in the pharmaceutical industry and academia as well as postgraduate students in pharmaceutical science will find this a valuable resource.