Biotechnological Applications Of Quorum Sensing Inhibitors
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Quorum Sensing And Its Biotechnological Applications
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Author : Vipin Chandra Kalia
language : en
Publisher: Springer
Release Date : 2018-08-11
Quorum Sensing And Its Biotechnological Applications written by Vipin Chandra Kalia and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-11 with Medical categories.
This book delves into the biotechnological applications of Quorum sensing (QS)- a peculiar gene-regulatory process of some microorganisms. Quorum Sensing allows a large bacterial population to work together in a coordinated manner to carry out metabolic activities, which individual bacterium cannot. The different chapters describe how, associating bioremediation process with energy generation is an economical proposal, for reducing pollution and managing biowastes. The book discusses how QS can be exploited for biotechnological applications in generating bioproducts, bioenergy, bioremediation, biosensors, health and agricultural activities. It further highlights how QS is becoming an integral part of synthetic biology for genetic circuits for producing: (i) novel products, (ii) biosensors, (iii) bioactive molecules, etc. The book is divided into different sections for a clear understanding of the applicability of QS in, the Environment, Energy, Agriculture and Health sectors.
Biotechnological Applications Of Quorum Sensing Inhibitors
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Author : Vipin Chandra Kalia
language : en
Publisher: Springer
Release Date : 2018-05-30
Biotechnological Applications Of Quorum Sensing Inhibitors written by Vipin Chandra Kalia and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-30 with Science categories.
This book discusses the practical applications of quorum sensing inhibitors for both human and plant health. Quorum sensing inhibitors that disrupt microbial biofilms can be employed to treat bacterial infections. The book describes the various bioactive molecules that can serve as quorum sensing inhibitors to combat deadly bacterial infections, in addition to several synthetic quorum sensing inhibitors. Quorum sensing is the mechanism through which bacteria develop antibiotic resistance. Intended to provide a clearer understanding of the practical applications of quorum sensing inhibitors, the book details how the problem of antibiotic resistance can be countered through the intelligent application of quorum sensing inhibitors.
Quorum Sensing
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Author : Giuseppina Tommonaro
language : en
Publisher: Academic Press
Release Date : 2019-04-15
Quorum Sensing written by Giuseppina Tommonaro and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-15 with Medical categories.
Quorum sensing (QS) is a process of bacterial cooperative behaviour that has an effect on gene regulation. This cell-to-cell communication system involves the production of signalling molecules according to cell density and growth stage. Virulence, the ability to infest a habitat and cause disease, is also governed by such communication signals. Quorum Sensing: Molecular mechanism and biotechnological application collects, describes and summarizes the most interesting results obtained from experts working on QS mechanisms. It contributes to the understanding of the molecular basis that regulates this mechanism, and describes new findings in fields of application. This volume describes the QS mechanism from its molecular basis to medical applications such as antibiotic therapy and involvement of QS in pathologies. This reference also analyzes its potential use in biotechnological applications such as food packaging, drug delivery, and marine biofilm. The broad scope of this title will be of significant use to researchers across several fields with interest in QS, including to microbiologists, chemists, biochemists and ecologists. Describes Quorum Sensing (QS) mechanisms from their molecular basis, to their clinical applications Spans several fields in relation to QS, including microbiology, chemistry, biochemistry and ecology Considers QS as an approach to the discovery of new antibiotics Looks at QS as a means to understand the microbial world and towards use of bacteria and their products in biotechnological applications Summarizes key results on QS mechanisms' molecular basis and fields of application
Quorum Sensing Vs Quorum Quenching A Battle With No End In Sight
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Author : Vipin Chandra Kalia
language : en
Publisher: Springer
Release Date : 2014-09-29
Quorum Sensing Vs Quorum Quenching A Battle With No End In Sight written by Vipin Chandra Kalia and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-29 with Science categories.
Microbial relationships with all life forms can be as free living, symbiotic or pathogenic. Human beings harbor 10 times more microbial cells than their own. Bacteria are found on the skin surface, in the gut and other body parts. Bacteria causing diseases are the most worrisome. Most of the infectious diseases are caused by bacterial pathogens with an ability to form biofilm. Bacteria within the biofilm are up to 1000 times more resistant to antibiotics. This has taken a more serious turn with the evolution of multiple drug resistant bacteria. Health Departments are making efforts to reduce high mortality and morbidity in man caused by them. Bacterial Quorum sensing (QS), a cell density dependent phenomenon is responsible for a wide range of expressions such as pathogenesis, biofilm formation, competence, sporulation, nitrogen fixation, etc. Majority of these organisms that are important for medical, agriculture, aquaculture, water treatment and remediation, archaeological departments are: Aeromonas, Acinetobacter, Bacillus, Clostridia, Enterococcus, Pseudomonas, Vibrio and Yersinia spp. Biosensors and models have been developed to detect QS systems. Strategies for inhibiting QS system through natural and synthetic compounds have been presented here. The biotechnological applications of QS inhibitors (QSIs) in diverse areas have also been dealt with. Although QSIs do not affect growth and are less likely to impose selective pressure on bacteria, however, a few reports have raised doubts on the fate of QSIs. This book addresses a few questions. Will bacteria develop mechanisms to evade QSIs? Are we watching yet another defeat at the hands of bacteria? Or will we be acting intelligently and survive the onslaughts of this Never Ending battle?
Trends In Quorum Sensing And Quorum Quenching
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Author : Jamuna A. Bai
language : en
Publisher: CRC Press
Release Date : 2020-05-25
Trends In Quorum Sensing And Quorum Quenching written by Jamuna A. Bai and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-25 with categories.
The book on Trends in Quorum Sensing and Quorum Quenching: New Perspectives and Applications focuses on the recent advances in the field of quorum sensing in bacteria and the novel strategies for quorum sensing inhibition. The topics covered are multidisciplinary and wide ranging from quorum sensing phenomenon in pathogenic bacteria, food spoilers and agriculturally relevant bacteria. The potential application of quorum sensing inhibitors including small molecules, bioactives, natural compounds and quorum quenching enzymes in controlling bacterial infections, in aquaculture and biofouling are also discussed. Special focus is given to exploring quorum sensing inhibitors from microbes and flora inhabiting biodiversity rich regions including tropical rain forests, various tropical soils and oceans. Key features: Covers the fundamental aspects and the progresses and the challenges in the field and the future trend Reviews quorum sensing in gram positive and gram negative bacteria of clinical, agricultural and industrial relevance Discusses the application of quorum sensing inhibitors from lab to clinical and environmental settings Provides comprehensive coverage on bacterial signaling mechanism V. Ravishankar Rai earned his MSc and PhD from the University of Mysore, India. Currently, Dr. Rai is working in the Department of Studies in Microbiology, University of Mysore, India. He has been awarded fellowship of UNECSO Biotechnology Action Council, Paris (1996) to visit Murdoch University, Perth, Indo-Israel Cultural Exchange Fellowship (1998), Biotechnology Overseas fellowship, Government of India (2008), Indo-Hungarian Exchange fellowship to visit Budapest (2011) and Bilateral Exchange Fellowship by Indian National Academy of Sciences to visit Turkey (2016). He was invited by Academia Sinica, Taiwan as Visiting Fellow (2010). He received Incoming fellowship from Cardiff University, United Kingdom (2017). Recently, he was invited by Centre of Excellence for Biomedical and Biomaterials Research, Mauritius (2018). He has been awarded Bilateral Exchange Fellowship by Indian National Academy of Sciences to visit Germany (2019), Eric Ojala fund International Travel Fellowship to visit Massey University (2019) and Cambridge-Hamied Visiting Lecture Scheme (2020). Jamuna A Bai has completed her MSc and PhD in Microbiology from University of Mysore, India. She is currently working as an Assistant Professor in JSS Academy of Higher Education Research, India. She has previously worked as Research Associate in UGC sponsored University with Potential Excellence Project and ICMR Senior Research Fellow in University of Mysore, India. Her research interest includes food safety, role of quorum sensing and biofilms in food-related bacteria and developing quorum-sensing inhibitors. She is presently working on antimicrobial application of functionalized nanomaterials against pathogens.
Fundamentals Of And Applications Based On Quorum Sensing And Quorum Sensing Interference
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Author : Cristina García-Aljaro
language : en
Publisher: Frontiers Media SA
Release Date : 2020-01-23
Fundamentals Of And Applications Based On Quorum Sensing And Quorum Sensing Interference written by Cristina García-Aljaro and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-23 with categories.
Background Bacteria use quorum sensing (QS) circuits to coordinate various activities (among which biofilm formation and the expression of virulence factors) based on the presence of signaling molecules. Different families of signal molecules have been identified in Gram positive and Gram negative bacteria (e.g. autoinducer peptides and acyl homoserine lactones). Similarly, different quorum sensing antagonists interfering with these system have been found in nature, promoting a new and promising field of research, quorum sensing interference. One of the most intensively studied applications of quorum sensing interference is its use as an alternative or synergycally with antibiotics to fight (antibiotic-resistant) bacterial pathogens. Many studies have been published claiming quorum sensing inhibitory activity of natural and synthetic compounds. However, after decades of research, several questions regarding the suitability of this approach to fight bacterial pathogens remain unanswered, including the risk that pathogens will develop resistance against quorum quenching. Meanwhile, the interest in quorum sensing has increased considerably, and this has broadened the fields where it can find biotechnological, environmental and industrial applications, such as anti biofouling, steering fermentations, bioremediation and wastewater treatment. Goal and scope The goal of this Research Topic is to broaden the knowledge of the phenotypes regulated by quorum sensing and the advances in quorum sensing interference. Deciphering microorganism language and the different phenotypes regulated by microbial signalling systems is a frontier for the development of new tools for the management of microorganisms to fulfil human needs with a broad application in different areas such as medicine, environmental sciences and industry.
Biotechnological Applications Of Polyhydroxyalkanoates
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Author : Vipin Chandra Kalia
language : en
Publisher: Springer
Release Date : 2019-01-24
Biotechnological Applications Of Polyhydroxyalkanoates written by Vipin Chandra Kalia and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-24 with Science categories.
This book presents the latest research on the uses of polyhydroxyalkanoates (PHA), introducing readers to these natural, biodegradable polyesters produced by microorganisms, their functions and applications. The individual chapters discuss the various potentials of these bioplastics, which offer an attractive alternative to non-biodegradable plastics. The book also describes the diverse medical and biomedical applications of PHAs, including their use as drug carriers, memory enhancers, and biocontrol agents, and examines their role in creating a more sustainable economy – which is the need of the hour.
Trends In Quorum Sensing And Quorum Quenching
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Author : V. Ravishankar Rai
language : en
Publisher: CRC Press
Release Date : 2020-05-04
Trends In Quorum Sensing And Quorum Quenching written by V. Ravishankar Rai and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-04 with Science categories.
The book on Trends in Quorum Sensing and Quorum Quenching: New Perspectives and Applications focuses on the recent advances in the field of quorum sensing in bacteria and the novel strategies developed for quorum sensing inhibition. The topics covered are multidisciplinary and wide-ranging,and includes quorum sensing phenomenon in pathogenic bacteria, food spoilers, and agriculturally relevant bacteria. The applications of quorum sensing inhibitors such as small molecules, bioactives, natural compounds, and quorum quenching enzymes in controlling bacterial infections in clinical settings, agriculture and aquaculture are discussed. The potential use of quorum quenching enzymes for mitigating biofouling is also covered. Special focus is given to exploring quorum sensing inhibitors from microbes and flora inhabiting biodiversity rich regions including tropical rain forests and marine environments. Key features: Covers the fundamental aspects, the progress and challenges in the field of quorum sensing and quorum quenching Reviews quorum sensing in Gram-positive and Gram-negative bacteria of clinical, agricultural, and industrial relevance Discusses the application and future trends of quorum sensing inhibitors from lab to clinical and environmental settings Provides comprehensive coverage on molecular mechanisms in bacterial signaling
Advances In Nano And Biochemistry
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Author : Pranay Pradeep Morajkar
language : en
Publisher: Elsevier
Release Date : 2023-05-23
Advances In Nano And Biochemistry written by Pranay Pradeep Morajkar and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-23 with Science categories.
Advances in Nano and Biochemistry: Environmental and Biomedical Applications gives insights into this advanced interdisciplinary science that encompasses the principles of physics and physical chemistry for the investigation of various processes and problems in biological systems. The book is a concise culmination of biophysical chemistry knowledge acquired through core concepts and advanced technologies for addressing emerging challenges in environmental and biomedical applications. Sections cover early diagnostic techniques and accurate treatment strategies using bioinspired, sustainable technologies, including nanomaterials, nanoenzymes, biopolymers, electrochemical biomolecule sensors, biocompatible magnetic nanomaterials, quantum dots and hybrid structures, and DNA nanotechnology. Other sections discuss advanced technologies for sensing and remedying environmental pollutants, including but not limited to, photocatalytic oxidations, gum polysaccharides based nanostructured materials, bio-inspired and biocompatible nanomaterials, hydrogel nanocomposites, and contemporary enzymes and nanozymes based?technologies. Ultimately, the state-of-the-art chapters in this book will empower researchers to combine two complementary elements - chemical analysis use and biomedical applications. Provides the fundamental concepts of biophysical chemistry and emerging technologies to solve environmental and biomedical problems Describes the latest breakthrough research in biophysical chemistry and its applications to better understand biological systems Supports development of the latest disease diagnostic and treatment technologies Includes advances in physical chemistry and biology for the monitoring and remediation of environmental pollutants
Bioresources And Bioprocess In Biotechnology
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Author : Shiburaj Sugathan
language : en
Publisher: Springer
Release Date : 2017-05-26
Bioresources And Bioprocess In Biotechnology written by Shiburaj Sugathan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-26 with Science categories.
This book is a compilation of detailed articles on various products and services that can be derived from bioresources through bioprocess. It offers in-depth discussions and case studies on commercially and therapeutically important enzymes, antimicrobials, anti-cancer molecules and anti-inflammatory substances. It also includes a separate section on emerging trends in bioactive substances research. This unique book is a valuable source of information for biotechnologists and bioprocess experts as well as academics and researchers who are actively involved in product and process development.