Birth Life And Death Of Dopaminergic Neurons In The Substantia Nigra
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Birth Life And Death Of Dopaminergic Neurons In The Substantia Nigra
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Author : Giuseppe di Giovanni
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-09-02
Birth Life And Death Of Dopaminergic Neurons In The Substantia Nigra written by Giuseppe di Giovanni and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-02 with Medical categories.
This book provides a unique and timely multidisciplinary synthesis of our current knowledge of the anatomy, pharmacology, physiology and pathology of the substantia nigra pars compacta (SNc) dopaminergic neurons. The single chapters, written by top scientists in their fields, explore the life cycle of dopaminergic neurons from their birth to death, the cause of Parkinson's disease, the second most common and disabling condition in the elderly population. Nevertheless, the intracellular cascade of events leading to dopamine cell death is still unknown and, consequently, treatment is symptomatic rather than preventive. The mechanisms by which alterations cause neuronal death, new therapeutic approaches and the latest evidence of a possible de novo neurogenesis in the SNc are reviewed and singled out in different chapters. This book bridges basic science and clinical practice and will prepare the reader for the next few years, which will surely be eventful in terms of the progress of dopamine research.
Computational Neuroscience Models Of The Basal Ganglia
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Author : V. Srinivasa Chakravarthy
language : en
Publisher: Springer
Release Date : 2018-03-21
Computational Neuroscience Models Of The Basal Ganglia written by V. Srinivasa Chakravarthy and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-21 with Technology & Engineering categories.
The book is a compendium of the aforementioned subclass of models of Basal Ganglia, which presents some the key existent theories of Basal Ganglia function. The book presents computational models of basal ganglia-related disorders, including Parkinson’s disease, schizophrenia, and addiction. Importantly, it highlights the applications of understanding the role of the basal ganglia to treat neurological and psychiatric disorders. The purpose of the present book is to amend and expand on James Houk’s book (MIT press; ASIN: B010BF4U9K) by providing a comprehensive overview on computational models of the basal ganglia. This book caters to researchers and academics from the area of computational cognitive neuroscience.
5 Ht Interaction With Other Neurotransmitters Experimental Evidence And Therapeutic Relevance Part B
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Author :
language : en
Publisher: Elsevier
Release Date : 2021-03-26
5 Ht Interaction With Other Neurotransmitters Experimental Evidence And Therapeutic Relevance Part B written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-26 with Science categories.
The Progress in Brain Research series highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Covers all key aspects of current research on 5-HT interaction with other neurotransmitters Provides extensively referenced chapters, thus giving readers a comprehensive list of resources on topics covered Includes comprehensive and in-depth background information written in a clear form that is accessible to both specialists and non-specialists
Bioencapsulation Of Living Cells For Diverse Medical Applications
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Author : Eva Maria Brandtner
language : en
Publisher: Bentham Science Publishers
Release Date : 2013-05-31
Bioencapsulation Of Living Cells For Diverse Medical Applications written by Eva Maria Brandtner and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-31 with Medical categories.
Bioencapsulation (or microencapsulation) of cells and their implantation into a body of immunoprotected cells allows researchers to revive a missing or defective function in the cells. Microencapsulated cells have reached the clinic where they have been shown to be safe and efficacious in numerous clinical trials. Cell types that have been encapsulated for therapeutic purposes include hybridomas, islet cells, "platform" cell lines e.g. HEK293 and CHO cells as well as an increasing focus on the encapsulation of stem cells. This e-book explains the different methods used for achieving cell bioencapsulation based on different polymers e.g. alginate, cellulose sulphate and agarose. Other chapters in this book subsequently describe the use of cell encapsulation in cancer therapy to improve on existing chemotherapies by reducing doses and thus side effects while increasing efficacy for long term in vivo production of (i) tumoricidal or virus neutralising antibodies, (ii) insulin to achieve a self regulating treatment for diabetes and (iii) neuron nurturing factors to treat CNS diseases such as epilepsy, disorders like Parkinson's disease, Alzheimer, Amyotrophic lateral sclerosis, Huntington's disease and pathologies caused by trauma and/or ischemic processes. The book also includes a chapter reviewing the genetic engineering of cells to allow controlled production of biotherapeutics from encapsulated cells. This is a unique and timely book which brings together contributions from some of the leading researchers in the field of cell encapsulation. Interested readers are provided an overview of the exciting developments and clinical experiences of researchers with cell bioencapsulation.
Handbook Of Basal Ganglia Structure And Function
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Author : Heinz Steiner
language : en
Publisher: Academic Press
Release Date : 2010-03-17
Handbook Of Basal Ganglia Structure And Function written by Heinz Steiner and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-17 with Medical categories.
The Basal Ganglia comprise a group of forebrain nuclei that are interconnected with the cerebral cortex, thalamus and brainstem. Basal ganglia circuits are involved in various functions, including motor control and learning, sensorimotor integration, reward and cognition. The importance of these nuclei for normal brain function and behavior is emphasized by the numerous and diverse disorders associated with basal ganglia dysfunction, including Parkinson’s disease, Tourette’s syndrome, Huntington’s disease, obsessive-compulsive disorder, dystonia, and psychostimulant addiction. The Handbook of Basal Ganglia provides a comprehensive overview of the structural and functional organization of the basal ganglia, with special emphasis on the progress achieved over the last 10-15 years. Organized in six parts, the volume describes the general anatomical organization and provides a review of the evolution of the basal ganglia, followed by detailed accounts of recent advances in anatomy, cellular/molecular, and cellular/physiological mechanisms, and our understanding of the behavioral and clinical aspects of basal ganglia function and dysfunction. Synthesizes widely dispersed information on the behavioral neurobiology of the basal ganglia, including advances in the understanding of anatomy, cell-molecular and cell-physiological mechanisms, and behavioral/clinical aspects of function and dysfunction Features a truly international cast of the preeminent researchers in the field Fully explores the clinically relevant impact of the basal ganglia on various psychiatric and neurological diseases
Movement Disorders In Psychiatry
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Author : Antonio Teixeira
language : en
Publisher: Oxford University Press
Release Date : 2022
Movement Disorders In Psychiatry written by Antonio Teixeira and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with Medical categories.
Movement Disorders in Psychiatry examines the complex interface between movement disorders and psychiatry, addressing both specific movement disorders in psychiatry and behavioral syndromes associated with diseases categorized as movement disorders. This volume provides an overview of clinical definitions and pathophysiology of movement disorders and reviews specific movement disorders associated with drugs of abuse and psychotropic medications, including tardive dyskinesia, akathisia, and neuroleptic malignant syndrome. Further chapters discuss movement disorders seen in primary psychiatric disorders, such as autism and schizophrenia, as well as diseases with concurrent movement disorder and behavioral symptoms, such as Huntington's disease, Parkinson's disease, frontotemporal dementia, Tourette's syndrome, and autoimmune conditions. Movement Disorders in Psychiatry offers an in-depth perspective on movement disorders with treatment and practical management strategies for related challenges in clinical practice.
Functional And Clinical Neuroanatomy
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Author : Jahangir Moini
language : en
Publisher: Academic Press
Release Date : 2020-02-21
Functional And Clinical Neuroanatomy written by Jahangir Moini and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-21 with Medical categories.
Functional and Clinical Neuroanatomy: A Guide for Health Care Professionals is a comprehensive, yet easy-to read, introduction to neuroanatomy that covers the structures and functions of the central, peripheral and autonomic nervous systems. The book also focuses on the clinical presentation of disease processes involving specific structures. It is the first review of clinical neuroanatomy that is written specifically for nurses, physician assistants, nurse practitioners, medical students and medical assistants who work in the field of neurology. It will also be an invaluable resource for graduate and postgraduate students in neuroscience. With 22 chapters, including two that provide complete neurological examinations and diagnostic evaluations, this book is an ideal resource for health care professionals across a wide variety of disciplines. Written specifically for "mid-level" providers in the field of neurology Provides an up-to-date review of clinical neuroanatomy based on the latest guidelines Provides a logical, step-by-step introduction to neuroanatomy Offers hundreds of full-color figures to illustrate important concepts Highlights key subjects in "Focus On" boxes Includes Section Reviews at critical points in the text of each chapter
Microbial Vitamins And Carotenoids In Food Biotechnology
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Author : Syed Amir Ashraf
language : en
Publisher: Elsevier
Release Date : 2024-05-06
Microbial Vitamins And Carotenoids In Food Biotechnology written by Syed Amir Ashraf and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-06 with Technology & Engineering categories.
In recent years, there has been a global surge in the production and application of vitamins and pigments in food and pharmaceuticals industries, leading to draw the attention of scientific communities to develop novel strategies to cope with world demand. Microbial vitamins and carotenoids in food biotechnology: Novel source and potential applications allow the audience to understand the current status of the biotechnological approaches used for the production of vitamins and carotenoids from microorganisms. The title provides important insights to understand the molecular mechanisms involved in microbial biosynthesis of vitamins and carotenoids. The chapters, all written by leading researchers from academia, help to put forward all the latest advancement concerning the production and applications of microbial vitamins and carotenoids. The book also provides the sustainable alternative to chemically synthesized compound and presents the wide coverage for the most promising sources of vitamins and carotenoids in food and pharmaceutical industries. This is a complete and unique resource beneficial for the scientific communities as well as food science and nutrition research students. Thoroughly explores biotechnological approaches surrounding the production and application of microbial vitamins and carotenoids in food processing and manufacturing industries Covers the major portion of novel source and various biotechnological approaches used for the production of various types of vitamins and carotenoids from microorganisms and their applications in food industry Contains up-to-date information required for the formulations of new products or protocols for enhancing production of specific compounds
Animal De Liberation
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Author : Jan Deckers
language : en
Publisher: Ubiquity Press
Release Date : 2016-07-28
Animal De Liberation written by Jan Deckers and has been published by Ubiquity Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-28 with Technology & Engineering categories.
In this book, Jan Deckers addresses the most crucial question that people must deliberate in relation to how we should treat other animals: whether we should eat animal products. Many people object to the consumption of animal products from the conviction that it inflicts pain, suffering, and death upon animals. This book argues that a convincing ethical theory cannot be based on these important concerns: rather, it must focus on our interest in human health. Tending to this interest demands not only that we extend speciesism—the attribution of special significance to members of our own species merely because they belong to the same species as ourself—towards nonhuman animals, but also that we safeguard the integrity of nature. In this light, projects that aim to engineer the genetic material of animals to reduce their capacities to feel pain and to suffer are morally suspect. The same applies to projects that aim to develop in-vitro flesh, even if the production of such flesh should be welcomed on other grounds. The theory proposed in this book is accompanied by a political goal, the ‘vegan project’, which strives for a qualified ban on the consumption of animal products. Deckers also provides empirical evidence that some support for this goal exists already, and his analysis of the views of others—including those of slaughterhouse workers—reveals that the vegan project stands firm in spite of public opposition. Many charges have been pressed against vegan diets, including: that they alienate human beings from nature; that they increase human food security concerns; and that they are unsustainable. Deckers argues that these charges are legitimate in some cases, but that, in many situations, vegan diets are actually superior. For those who remain doubtful, the book also contains an appendix that considers whether vegan diets might actually be nutritionally adequate.
Handbook Of Research On Critical Examinations Of Neurodegenerative Disorders
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Author : Uddin, Md. Sahab
language : en
Publisher: IGI Global
Release Date : 2018-07-31
Handbook Of Research On Critical Examinations Of Neurodegenerative Disorders written by Uddin, Md. Sahab and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-31 with Medical categories.
Neurodegeneration is a key feature of several diseases that are referred to as neurodegenerative diseases. The process of neurodegeneration is not well-understood so the diseases that stem from it have, as yet, no cures. As such, studying the effects of these disorders can provide insight into the treatment, prevention, and future opportunities and challenges in this growing field. The Handbook of Research on Critical Examinations of Neurodegenerative Disorders is a critical scholarly resource that provides an extensive explanation of various neurodegenerative disorders based on existing studies to clarify etiology, pathological mechanisms, diagnosis, therapeutic interventions, as well as current status and future opportunities and challenges. Featuring coverage on a broad range of topics such as dementia, mitochondrial dysfunction, and risk factors, this book is geared towards neurobiologists, neuropsychologists, neurophysiologists, neuropathologists, medical professionals, academicians, and researchers seeking research on the complexity of neurodegenerative disorders.