Bone Biology And Healing
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Bone Biology And Healing
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Author : Glyn O Phillips
language : en
Publisher: World Scientific
Release Date : 2003-01-23
Bone Biology And Healing written by Glyn O Phillips and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-01-23 with Medical categories.
This book describes succinctly the factors which affect the incorporation of massive and morsellised allografts after transplantation. Unless special precautions are taken, massive allografts when implanted can undergo stress fatigue, due to the limited incorporation at the graft-host interface. Immunological and cell signalling growth factors can be shown to greatly influence the behaviour of the graft. The bone-biological processes are illustrated in terms of demineralised bone, which can initiate bone induction due to the protection and availability of the original bone-morphogenic protein. The main message is that transplantation without consideration of the underlying biological healing processes can reduce the effectiveness of the procedure. Contents:The Biology of Massive Bone Allografts: Understanding Allograft Biology and Adapting it Towards Successful Clinical ApplicationsImmunology of Bone Allografts: Current Knowledge: The Application of Growth Factors to Enhance Bone HealingBiology of Healing of Large Deep-Frozen Cortical Bone AllograftsEffect of Growth Factors on Bone Healing and the Clinical Applications of Autogenous Platelet-Rich Plasma Gel to Enhance Bone FormationBiology of Demineralised Bone and Its Clinical Use Readership: Orthopaedic surgeons who use tissue allografts in bone and related reconstructions. Keywords:Bone;Healing;Osteoinductive;Clinical;Immunology;Radiation
Bone Regeneration And Repair
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Author : Jay R. Lieberman
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-27
Bone Regeneration And Repair written by Jay R. Lieberman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-27 with Medical categories.
This collection of articles by leading orthopedic and craniofacial surgeons and researchers comprehensively reviews the biology of bone formation and repair, the basic science of autologous bone graft, allograft, bone substitutes, and growth factors, and explore their clinical application in patients with bone repair problems.
Basic And Applied Bone Biology
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Author : David B. Burr
language : en
Publisher: Academic Press
Release Date : 2019-02-20
Basic And Applied Bone Biology written by David B. Burr and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-20 with Science categories.
Basic and Applied Bone Biology, Second Edition, provides an overview of skeletal biology, from the molecular level, to the organ level, including cellular control, interaction and response, adaptive responses to various external stimuli, and the interaction of the skeletal system with other metabolic processes in the body. The book includes chapters that address how the skeleton can be evaluated through the use of various imaging technologies, biomechanical testing, histomorphometric analysis, and the use of genetically-modified animal models. Each chapter delves deep into the important details of topics covered to provide a solid understanding of the basics of bone biology. Bone biology researchers who also train undergraduate and graduate students in the lab will use this book constantly to orient new students on the basics of the field and as a background reference for many of the technical aspects of qualification in bone biology (e.g., mechanics, histomorphometry, genetic modification, biochemistry, etc.). Presents an in-depth overview of skeletal biology, from molecular to organ level Offers refresher level content for clinicians or researchers outside their areas of expertise Includes updated and complete references Incorporates expanded study questions at the end of each chapter for further exploration Covers topics relevant to a modern course in skeletal biology
Cortical Bone Healing After Internal Fixation And Infection
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Author : W.W. Rittmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Cortical Bone Healing After Internal Fixation And Infection written by W.W. Rittmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The danger of infection remains the most serious drawback to internal fixation. Prevention, using all available prophylactic measures should be the central feature in every surgical department. Though the infection rate may remain below the acceptable level of 2 %, the infected patient derives little comfort from the large number of excellent results in other people. We must discover the best way to offer these patients a favourable prognosis. This should not be based on intuition but on clear proven guiding principles. Planning the treatment for a patient whose internal fixation has become septic must decide between steps which may have advantages or disadvan tages. The disadvantage of the presence of a foreign body must be weighed against the advantage of rigidity. The authors have taken up this challenge by planned animal experiments to study the healing of internally fixed fractures which have been infected with staphylococci. They have shown that under stable conditions, even massive infection did not destroy the healing process in cortical bone. Even under these circumstances fracture union, in the form of primary bone healing, can occur even if with less regularity than in unin fected internal fixation.
Bone And Bones
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Author : Joseph Peter Weinmann
language : en
Publisher:
Release Date : 1955
Bone And Bones written by Joseph Peter Weinmann and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1955 with Bone categories.
Cortical Bone Healing After Internal Fixation And Infection
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Author : M Allgower
language : en
Publisher:
Release Date : 1974-12-09
Cortical Bone Healing After Internal Fixation And Infection written by M Allgower and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1974-12-09 with categories.
Principles Of Bone Regeneration
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Author : Jona J. Sela
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-03-13
Principles Of Bone Regeneration written by Jona J. Sela and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-13 with Technology & Engineering categories.
Principles of Bone Regeneration is a timely publication that addresses the modern aspects of bone healing and repair. This exciting new volume details the convergence of the different experimental and clinical approaches designed for the study and treatment of bone healing in its diverse forms and under varying conditions. Bone healing is affected by a multitude of genetic, environmental, mechanical, cellular and endocrine variables which eventually lead to changes in gene expression that enhance the guided action of osteoblasts (and chondroblasts) to lay down bone that restores, or even improves, the skeletal load bearing capacity. Recent breakthroughs in understanding the regulatory aspects of bone formation and resorption, in both research and clinical arenas offer new modalities to induce, enhances and guide repair processes in bone for the benefit of millions of patients with conditions such as nonunion fractures, critical size defects, orthodontic tooth movement, periodontal bone loss, intraosseous implants and deformed bones.
Bone Morphogenetic Protein And Collagen
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Author : Glyn O Phillips
language : en
Publisher: World Scientific
Release Date : 2004-01-16
Bone Morphogenetic Protein And Collagen written by Glyn O Phillips and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-01-16 with Medical categories.
What are bone morphogenetic proteins (BMPs) and how can they be used in orthopaedic practice? Ever since Urist proposed in 1976 that protein factors from cortical bone appeared to modulate bone healing in animals, there has been a search for these mysterious osteoinductive components. Now that their structure has been elucidated, they have been purified and cloned, and are now available for the improvement of bone healing. The best source of BMPs is demineralised bone. This bone allograft is used to achieve greater osteoinductive capacity. But are the actions of procurement, processing, demineralisation and sterilisation harmful to the BMPs? Unless the BMPs can be assayed, neither their clinical nor their scientific effectiveness can be appraised. All these aspects are logically and scientifically described in this volume. In addition, there is a review of the biochemistry of one of the two main components of bone, namely collagen. This subject is itself a confusing but rapidly growing field. This comprehensive review describes the procedures for building up bone in vivo and in vitro. Bone Morphogenetic Protein and Collagen answers most of the questions of orthopaedic surgeons and tissue bankers on how BMPs can be produced and used to their maximum effectiveness. Contents:From Bone Allografts to Synthetic Bone Grafts: Bone Morphogenetic Proteins and OsteoinductionThe Osteoinductive Properties of Demineralised Bone Matrix GraftsProcessing Factors Contributing to Production of Maximally Osteoinductive Demineralised Ground BoneClinical Effectiveness of Demineralised Bone Matrix Assayed in Human Cell CultureThe Influence of Sterilisation on the Osteoinductive Properties of Bone in Rat Bone Marrow Cell CultureCollagen Biochemistry: An Overview Readership: Orthopaedic surgeons who use tissue allografts in bone and related reconstructions. Keywords:Bone;Healing Osteoinductive;Clinical;Immunology;RadiationReviews:“this series in allografts in bone healing: biology and clinical applications is a very commendable idea …”International Orthopaedics
Bone Tissue Engineering
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Author : Jeffrey O. Hollinger
language : en
Publisher: CRC Press
Release Date : 2004-10-14
Bone Tissue Engineering written by Jeffrey O. Hollinger and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-10-14 with Medical categories.
Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t
Engineered Bone
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Author : Herve Petite
language : en
Publisher: CRC Press
Release Date : 2005-08-15
Engineered Bone written by Herve Petite and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-08-15 with Science categories.
This book addresses relevant issues that tissue-engineering researchers must consider when planning new strategies, especially in the bone and cartilage field. It describes transcription factors that are essential in bone development, and deals with bone healing.