Bone Cell Biomechanics Mechanobiology And Bone Diseases
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Bone Cell Biomechanics Mechanobiology And Bone Diseases
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Author : Airong Qian
language : en
Publisher: Elsevier
Release Date : 2023-08-28
Bone Cell Biomechanics Mechanobiology And Bone Diseases written by Airong Qian and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-28 with Reference categories.
Bone Cell Biomechanics, Mechanobiology and Bone Diseases provides a comprehensive overview of recent knowledge and advances of bone cell biomechanics and related bone diseases, highlighting the cellular basis for bone responding to mechanical stimuli. The book not only provides a general overview of bone cell biology, but also the most recent advances of bone cell biomechanics, mechanobiology, the relationship between bone cell biomechanics and bone diseases, as well as the underlying mechanism. This will be useful in understanding the role of mechanobiology in bone health and bone diseases, as well for investigating novel strategies for diagnosis and therapy of bone diseases. Cells covered in the book include osteocyte, BM-MSC, osteoblast, osteoclast and chondrocyte. Cone diseases covered are osteoporosis, scoliosis and osteoarthritis. This comprehensive reference is written for researchers, scientists, clinicians and students. Presents a comprehensive introduction of current knowledge and recent advances of bone cell biomechanics Introduces new technologies for bone cell research Discusses the bone cell mechanotransduction, mechanism and bone diseases
Skeletal Aging And Osteoporosis
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Author : Matthew J. Silva
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-08-30
Skeletal Aging And Osteoporosis written by Matthew J. Silva and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-30 with Technology & Engineering categories.
The focus of this book is on mechanical aspects of skeletal fragility related to aging and osteoporosis. Topics include: Age-related changes in trabecular structure and strength; age-related changes in cortical material properties; age-related changes in whole-bone structure; predicting bone strength and fracture risk using image-based methods and finite element analysis; animal models of osteoporosis and aging; age-related changes in skeletal mechano responsiveness; exercise and physical interventions for osteoporosis.
Multiscale Mechanobiology Of Bone Remodeling And Adaptation
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Author : Peter Pivonka
language : en
Publisher: Springer
Release Date : 2017-06-20
Multiscale Mechanobiology Of Bone Remodeling And Adaptation written by Peter Pivonka and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-20 with Science categories.
The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors. Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.
Bone Remodeling Process
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Author : Rabeb Ben Kahla
language : en
Publisher: Academic Press
Release Date : 2021-08-14
Bone Remodeling Process written by Rabeb Ben Kahla and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-14 with Technology & Engineering categories.
Bone Remodeling Process: Mechanics, Biology, and Numerical Modeling provides a literature review. The first part of the book discusses bones in a normal physiological condition, bringing together the involved actors and factors reported over the past two decades, and the second discusses pathological conditions, highlighting the attack vectors of each bone disease. The third part is devoted to the mathematical descriptions of bone remodeling, formulated to develop models able to provide information that is not amenable to direct measurement, while the last part focuses on models using the finite element method in investigating bone biomechanics.This book creates an overall image of the complex communication network established between the diverse remodeling actors, based on overwhelming control evidence revealed over recent years, as well as visualizes the remodeling defects and possible treatments in each case. It also regroups the models allowing readers to analyze and assess bone mechanical and biological properties. This book details the cellular mechanisms allowing the bone to adapt its microarchitecture to the requirements of the human body, which is the main issue in bone biology and presents the evolution of mathematical modeling used in a bone computer simulation. Each chapter covers a core topic in bone biomechanics Provides a multidisciplinary view that effectively links orthopaedics, cellular biology, mechanics, and computer simulation Draws an overall image about bone biology and cell interactions, for identifying cell populations that are crucial for the remodeling process
Mechanobiology In Health And Disease
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Author : Stefaan Verbruggen
language : en
Publisher: Academic Press
Release Date : 2018-08-09
Mechanobiology In Health And Disease written by Stefaan Verbruggen and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-09 with Technology & Engineering categories.
Mechanobiology in Health and Disease brings together contributions from leading biologists, clinicians, physicists and engineers in one convenient volume, providing a unified source of information for researchers in this highly multidisciplinary area. Opening chapters provide essential background information on cell mechanotransduction and essential mechanobiology methods and techniques. Other sections focus on the study of mechanobiology in healthy systems, including bone, tendons, muscles, blood vessels, the heart and the skin, as well as mechanobiology studies of pregnancy. Final chapters address the nascent area of mechanobiology in disease, from the study of bone conditions, skin diseases and heart diseases to cancer. A discussion of future perspectives for research completes each chapter in the volume. This is a timely resource for both early-career and established researchers working on mechanobiology. Provides an essential digest of primary research from many fields and disciplines in one convenient volume Covers both experimental approaches and descriptions of mechanobiology problems from mathematical and numerical perspectives Addresses the hot topic of mechanobiology in disease, a particularly dynamic field of frontier science
Bone Mechanics
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Author : Stephen C. Cowin
language : en
Publisher: CRC Press
Release Date : 1989
Bone Mechanics written by Stephen C. Cowin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Medical categories.
This informative volume summarizes what is known about bone mechanics. It describes the methods used to acquire that knowledge and suggests the nature of future research on this topic. This easy-to-read book keeps mathematical notation simple and minimal and presents data in summary form. Bone Mechanics is concerned with the mechanical behavior and functional stress adaptation of whole bones as structural elements, the mechanical behavior and functional adaptation of bone tissue as material, and the physiological significance of the mechanical properties of bone and the biological response of bone to applied stress. Orthopaedic surgeons, dentists, anatomists, biologists, biomedical engineers and physiologists are among those who will find this volume to be of interest.
Mechanobiology
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Author : Glen L. Niebur
language : en
Publisher: Elsevier
Release Date : 2019-12-01
Mechanobiology written by Glen L. Niebur and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-01 with Science categories.
Mechanobiology: From Molecular Sensing to Disease will provide a review of the current state of understanding of mechanobiology and its role in health and disease. It covers: Current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli, A review of diseases that with known or purported mechanobiological underpinnings; The role of mechanobiology in tissue engineering and regenerative medicine; Experimental methods to capture mechanobiological phenomena; Computational models in mechanobiology. Presents our current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli Provides a review of diseases with known or purported mechanobiological underpinnings Includes the role of mechanobiology in tissue engineering and regenerative medicine Covers experimental methods to capture mechanobiological phenomena
Skeletal Tissue Mechanics
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Author : R. Bruce Martin
language : en
Publisher: Springer
Release Date : 2015-10-29
Skeletal Tissue Mechanics written by R. Bruce Martin and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-29 with Medical categories.
This textbook describes the biomechanics of bone, cartilage, tendons and ligaments. It is rigorous in its approach to the mechanical properties of the skeleton yet it does not neglect the biological properties of skeletal tissue or require mathematics beyond calculus. Time is taken to introduce basic mechanical and biological concepts, and the approaches used for some of the engineering analyses are purposefully limited. The book is an effective bridge between engineering, veterinary, biological and medical disciplines and will be welcomed by students and researchers in biomechanics, orthopedics, physical anthropology, zoology and veterinary science. This book also: Maximizes reader insights into the mechanical properties of bone, fatigue and fracture resistance of bone and mechanical adaptability of the skeleton Illustrates synovial joint mechanics and mechanical properties of ligaments and tendons in an easy-to-understand way Provides exercises at the end of each chapter
Basic Orthopaedic Biomechanics And Mechano Biology
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Author : Van C. Mow
language : en
Publisher: Lww
Release Date : 2015-04-24
Basic Orthopaedic Biomechanics And Mechano Biology written by Van C. Mow and has been published by Lww this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-24 with categories.
Completely revised and updated, the Third Edition of this classic text reflects the latest advances in research on orthopaedic biomechanics and the successful applications of biomechanical principles in fracture fixation, prosthetic implant design, and hip and knee arthroplasty. For this Third Edition, Dr. Mow is joined by new co-editor Rik Huiskes, PhD, an Editor-in-Chief of the Journal of Biomechanics and an internationally renowned authority in the field. New chapters cover biomaterials, biomechanical principles of cartilage and bone tissue engineering, and biomechanics of fracture fixation and fracture healing.
The Computational Mechanics Of Bone Tissue
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Author : Jorge Belinha
language : en
Publisher: Springer Nature
Release Date : 2020-02-11
The Computational Mechanics Of Bone Tissue written by Jorge Belinha and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-11 with Science categories.
This book offers a timely snapshot of computational methods applied to the study of bone tissue. The bone, a living tissue undergoing constant changes, responds to chemical and mechanical stimuli in order to maximize its mechanical performance. Merging perspectives from the biomedical and the engineering science fields, the book offers some insights into the overall behavior of this complex biological tissue. It covers three main areas: biological characterization of bone tissue, bone remodeling algorithms, and numerical simulation of bone tissue and adjacent structures. Written by clinicians and researchers, and including both review chapters and original research, the book offers an overview of the state-of-the-art in computational mechanics of bone tissue, as well as a good balance of biological and engineering methods for bone tissue analysis. An up-to-date resource for mechanical and biomedical engineers seeking new ideas, it also promotes interdisciplinary collaborations to advance research in the field.