Bone Marrow Failure Syndromes
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Bone Marrow Failure Syndromes
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Author : Neal S. Young
language : en
Publisher:
Release Date : 2000
Bone Marrow Failure Syndromes written by Neal S. Young and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medical categories.
Researchers from the National Institutes of Health in Bethesda, Maryland, along with a few other contributors, explore ten disorders that may be linked only by resulting in a lowered blood count that can be traced to the failure of the bone marrow. They are acquired aplastic anemia, Fanconi's anemia, myelodysplastic syndromes, paroxysmal nocturnal hemoglobinuria, myelofibrosis, pure red cell aplasia, agranulocytosis, acquired amegakaryocytic thrombocytopenic purpura, bone marrow failure related to human immunodeficiency virus, and T cell large granular lymphocyte lymphoproliferative disorder. The text is supported by 13 color plates. The index is particularly detailed. Annotation copyrighted by Book News, Inc., Portland, OR
Aplastic Anemia And Other Bone Marrow Failure Syndromes
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Author : Nasrollah T. Shahidi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Aplastic Anemia And Other Bone Marrow Failure Syndromes written by Nasrollah T. Shahidi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
During the past decade, there have been numerous direct and indirect scientific contributions to both the etiology and therapy of aplastic anemia and related bone marrow failure syndromes. Clinical observations, such as autologous bone marrow recovery after conditioning with immunosup pressive agents for bone marrow transplantation; failure to achieve en graftment in some identical twins without prior immunosuppressive ther apy; and hematologic response to immunosuppressive agents, have led to the concept of immune-mediated etiology of acquired aplastic anemia. Such a concept was further strengthened by laboratory findings, implicat ing the role of activated cytotoxic T lymphocytes and abnormal produc tion of inhibitory lymphokines. The immunologic mechanisms may also apply to the idiosyncratic bone marrow aplasias associated with drugs, toxic chemicals, and viruses. These agents may alter normal cellular recog nition sites by interacting with cellular components and result in loss of self tolerance. Immunologic mechanisms have long been advocated in many other organ failures, and the hemopoietic organ is no exception. It is of interest that parallel clinical and laboratory investigations in juvenile diabetes mellitus type I and in rodent models of this disease have yielded results compatible with the same pathogenic mechanisms. The infiltration of pancreatic islets by activated T lymphocytes, functional and morphological alterations of islet cells upon incubation with lymphokines such as gamma interferon and tumor necrosis factor, and clinical response to cyclosporine are a few examples.
Bone Marrow Failure
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Author : Gary M. Kupfer
language : en
Publisher: Springer
Release Date : 2018-09-29
Bone Marrow Failure written by Gary M. Kupfer and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-29 with Medical categories.
This book presents the latest scientific knowledge on inherited and acquired bone marrow failure syndromes, describing the advances in understanding of genetics and pathophysiology that have been achieved as a result of high-throughput DNA sequencing, RNA expression studies, and modern biochemistry techniques. The full range of relevant conditions is covered, including acquired aplastic anemia, Fanconi anemia, ribosomopathies, telomeropathies, dyskeratosis congenita, Shwachman-Diamond syndrome, Diamond-Blackfan anemia, and congenital neutropenias and thrombocytopenias. In addition, it is explained how the study of these rare diseases has uncovered important new science and elucidated the pathophysiology of more common hematological and oncological diseases. A treatment-specific chapter describes options ranging from the conventional to the cutting edge. Bone Marrow Failure will be of value for both trainee and practicing hematologists and oncologists.
The Ebmt Handbook
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Author : Nicolaus Kröger
language : en
Publisher:
Release Date : 2020-10-08
The Ebmt Handbook written by Nicolaus Kröger and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-08 with Medical categories.
This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.
Congenital And Acquired Bone Marrow Failure
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Author : Mahmoud Deeb Aljurf
language : en
Publisher: Elsevier
Release Date : 2016-12-23
Congenital And Acquired Bone Marrow Failure written by Mahmoud Deeb Aljurf and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-23 with Science categories.
Congenital and Acquired Bone Marrow Failure is a comprehensive guide to congenital and acquired bone marrow failure in adult and pediatric patients. Chapters are divided into two sections, acquired aplastic anemia and inherited bone marrow failure syndromes. Content ranges from the basic, to the translational, and from the epidemiology of acquired aplastic anemia and telomere biology, to the management, treatment, and supportive care of pediatric, adult, and geriatric patients. Contributors are world leading experts in the field of bone marrow failure. The book is required reading for residents, fellows, clinicians, and researchers across hematology, oncology, pathology, bone marrow transplantation, pediatrics, and internal medicine. Provides an overview of all congenital and acquired bone marrow failure syndromes Focuses on the molecular pathogenesis, clinical manifestation and diagnosis, laboratory features, and treatment of each disease within the syndromes Features the area of supportive care which is a topic of great interest to infectious disease physicians and those involved in transfusion services
Handbook Of Benign Hematology
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Author : Martha Pritchett Mims, MD, PhD
language : en
Publisher: Springer Publishing Company
Release Date : 2019-12-11
Handbook Of Benign Hematology written by Martha Pritchett Mims, MD, PhD and has been published by Springer Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-11 with Medical categories.
Handbook of Benign Hematology is a practical guide to the diagnosis and management of benign hematologic conditions. The book begins with a chapter on normal hematopoiesis and follows with chapters devoted to groups of blood disorders and syndromes including neutrophil disorders, nonmalignant myeloid disorders, bone marrow failure syndromes, myeloproliferative disorders, anemias, iron metabolism disorders, platelet disorders, hemostasis and coagulation defects, and thrombosis. Each disorder subtype covered features a clinical case, an introduction to the condition, details on diagnosis including applicable criteria and lab work needed, key diagnostic dilemmas, prognosis, treatment options, details on clinical trials and emerging clinical strategies, and bulleted key points to highlight clinical pearls and common pitfalls. The final chapters provide best practices for transfusion medicine and a guide to pharmacologic agents and their uses in clinical practice for adult and pediatric patients. The handbook is filled with tables and illustrations which highlight FDA-approved drug information, clinical trials data, hematopathologic characteristics of different disorders, important management criteria and more, making it the ideal handbook for those in practice or for review. The Editors and chapter authors are experienced academic practitioners in the fields of adult and pediatric hematology, pathology, blood banking, and pharmacology. Emphasizing best practices for patient management, this handbook is essential for oncologists, hematologists, trainees, and other practitioners who regularly or increasingly receive referrals to diagnose and treat adults or children with nonmalignant hematologic conditions. Key Features: Includes dozens of clinical cases covering all nonmalignant blood disorders Emphasizes patient management and best practices for disorders seen in adults and children Contains over 30 color images and numerous tables for quick reference Presents important details of all pharmacologic agents used to treat or manage hematologic disorders and their complications Purchase includes access to the ebook for use on most mobile devices or computers
Bone Marrow Failure Syndromes
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Author : Gabrielle Meyers
language : en
Publisher: Clinics: Internal Medicine
Release Date : 2009
Bone Marrow Failure Syndromes written by Gabrielle Meyers and has been published by Clinics: Internal Medicine this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Medical categories.
Our issues help you manage yours. Every year brings you new clinical challenges. Every Clinics issue brings you today's best thinking on the challenges you face. Whether you purchase these issues individually, or order a personal subscription (which includes online access to current and past issues at www.theclinics.com), the Clinics offer you an efficient way to update your know how...one issue at a time. Book jacket.
Aplastic Anemia And Other Bone Marrow Failure Syndromes
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Author : Nasrollah T. Shahidi
language : en
Publisher:
Release Date : 1990
Aplastic Anemia And Other Bone Marrow Failure Syndromes written by Nasrollah T. Shahidi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Anémie aplastique - Congrès categories.
Neonatal Hematology
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Author : Pedro A. de Alarcón
language : en
Publisher: Cambridge University Press
Release Date : 2021-02-18
Neonatal Hematology written by Pedro A. de Alarcón and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-18 with Medical categories.
An essential guide to the pathogenesis, diagnosis and management of hematologic problems in the neonate, covering erythrocyte disorders, leukocyte disorders, immunologic disorders and hemostatic disorders. Guidance is practical, including blood test interpretation, advice on transfusions and reference ranges for hematological values.
Inherited Bone Marrow Failure Syndromes
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Author :
language : en
Publisher:
Release Date : 2002
Inherited Bone Marrow Failure Syndromes written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Bone marrow categories.