Borna Disease Virus Infection In Cats
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Borna Disease Virus Infection In Cats
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Author : Anna-Lena Lundgren
language : en
Publisher:
Release Date : 1995
Borna Disease Virus Infection In Cats written by Anna-Lena Lundgren and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Cats categories.
Pilot Serological And Molecular Surveys Of Borna Disease Virus Infection Of Domestic Cats
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Author : Michelk Abamaku
language : en
Publisher:
Release Date : 2013
Pilot Serological And Molecular Surveys Of Borna Disease Virus Infection Of Domestic Cats written by Michelk Abamaku and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with categories.
Pilot serological and molecular diagnostic studies were undertaken on retrospective and prospective samples of plasma and PBMCs of domestic cats obtained from the William R. Pritchard Veterinary Medical Teaching Hospital at the University of California, Davis, and the Specialized Infectious Diseases Lab at the Veterinary Teaching Hospital, Colodrado State University, to assess this species for previous exposure and/or current infection with Borna Disease virus (BDV), in order to draw conclusions about the existence of Bornaviruses in the United States.Exploratory serological assessment of a convenience serum sample of cats seen at the VMTH-UC Davis, revealed circulating antibodies to Bornavirus antigens in 11 of 301 (3.7%) domestic cats tested by dual-labeling immunofluorescence (IFA) assay, optimized for enhanced specificity. An Indirect screening ELISA based on 2 recombinant BDV antigens (p24 and p40), on the other hand demonstrated low agreement (23.2%), limiting the diagnostic utility of the ELISA, in contrast with the highly specific dual-IFA. These dual-label IFA results represent the first report of seroreactivity to BDV antigens in domestic cats in North America, in the absence of overt neurological disease.Serological assessment of a stratified sample of 384 sera obtained from different geographical regions of the U.S., revealed a 2.3% seroprevalence of circulating antibodies to BDV antigens in 9 of 384 sera, by dual-label IFA, while 15 of 384 (3.9%) sera were reactive to BDVp24 and p40 recombinant proteins by the Luminex screen. In a second subgroup of 405 cat sera categorized by CNS disease status, the dual-IFA scored 15 of 405 (3.7%) sera reactive to BDV antigens, while 7 of 405 (1.7%) sera were reactive by the recombinant Luminex screen. We observed a high correlation in reactivity to BDV recombinants, and reactivity to an irrelevant recombinant protein (SPV VP2), leading to the suspicion that the observed Luminex seroreactivity was spurious. Given the inherent high specificity of the dual-IFA, we conclude that BDVs circulate at a prevalence of 2.3% in the U.S., basing on regionalized stratified sampling, as assessed by the dual-IFA assay. We were unable to make conclusions about relationships between reactivity to BDV and provenance, or CNS disease status, as these data were unavailable. Prospective molecular and serologic studies conducted on 462 samples of domestic cats seen at the VMTH-UC Davis revealed circulating antibodies to BDV-specific antigens in 19 sera (4.1%), but no detectable BDV genomes in paired PBMC samples, by conserved and degenerate probe and primer Bornavirus-specific real time PCR assays. Follow up case-based retrospective and prospective studies are recommended to comprehensively investigate CNS disease of undetermined etiology in domestic cats, for which the common differential diagnoses have been excluded, for potential BDV infection.
Characterization Of Feline Borna Disease Virus
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Author : Oluwafemi Oladele
language : en
Publisher:
Release Date : 2006
Characterization Of Feline Borna Disease Virus written by Oluwafemi Oladele and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with categories.
Modeling The Psychopathological Dimensions Of Schizophrenia
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Author : Mikhail Pletnikov
language : en
Publisher: Academic Press
Release Date : 2015-11-05
Modeling The Psychopathological Dimensions Of Schizophrenia written by Mikhail Pletnikov and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-05 with Psychology categories.
Modeling the Psychopathological Dimensions of Schizophrenia: From Molecules to Behavior is the first book to offer a comprehensive review of the new theoretical, clinical, and basic research framework that considers psychotic illness as a group of dimensional representations of psychopathology rather than as traditional distinct categorical diagnoses. Psychotic illness, typified by schizophrenia, is a devastating condition increasingly recognized as a disorder of abnormal brain development and dysconnectivity. Its complex etiology involves both genetic and environmental factors, as well as the interplay among them. This book describes the current understanding of the clinical and pathological features of schizophrenia, with a particular focus on the evolving conceptualization of schizophrenia and related diagnostic categories of psychotic illness as combinations of dimensional abnormalities. It provides an overview of modern strategies for generating cellular and whole animal models of schizophrenia as well as detailed reviews of the specific experimental preparations and paradigms aimed at molecular, developmental, and brain-network mechanisms that are the underlying aspects of abnormal behavior and various aspects of schizophrenia. This groundbreaking book is an authoritative overview of the translational impact of emerging clinical insights on basic research approaches in schizophrenia that will advance the reader’s understanding of the five major dimensions of psychopathology in schizophrenia and related psychoses and resolve the genetic and neurobiological underpinnings of these dimensions. Includes reviews of animal models that capture the most recent insights into the etiology and pathogenetic mechanisms of schizophrenia, with an emphasis on the translational potential of these models Contains a series of reviews of recently available cellular models for analysis of signaling pathways and gene expression, which complement behavioral neuroscience research in schizophrenia Edited and authored by leading researchers in the field of schizophrenia and related psychoses
Standards For Seat Belts For Use In Motor Vehicles
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Author : United States. National Bureau of Standards
language : en
Publisher:
Release Date : 1966
Standards For Seat Belts For Use In Motor Vehicles written by United States. National Bureau of Standards and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1966 with Automobiles categories.
Infectious Diseases Of The Dog And Cat E Book
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Author : Jane E. Sykes
language : en
Publisher: Elsevier Health Sciences
Release Date : 2013-09-27
Infectious Diseases Of The Dog And Cat E Book written by Jane E. Sykes and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-27 with Medical categories.
The definitive reference for the diagnosis, treatment, and prevention of small animal infections, Infectious Diseases of the Dog and Cat, 4th Edition delivers current, comprehensive information essential to the management of infectious diseases caused by viruses, rickettsiae, chlamydiae, mycoplasmas, bacteria, fungi, algae, protozoa, and unknown agents. Each section guides you through diagnostic testing for specific microorganisms, from sample collection to laboratory submission to interpretation of results, then details appropriate treatment measures and pharmacologic considerations for the various related infections. Full-color illustrations and hundreds of tables provide quick, convenient access to diagnostic and therapeutic guidelines, and thoroughly updated drug information helps you confidently administer appropriate dosages for the most effective treatment and prevention. The most comprehensive infectious disease coverage available helps you confidently address clinical problems related to infectious diseases in dogs and cats, and includes: Immunization strategies and environmental control of infections Immunodeficiency disorders Prevention of infection in multi-pet and shelter settings Immunocompromised people and their pets Vibrant full-color illustrations clarify disease features and modes of disease transmission for enhanced diagnostic accuracy and disease prevention. Convenient tables deliver therapeutic recommendations and drug dosages at a glance. Complete antimicrobial drug formulary provides fast, easy access to indications, recommended dosages, and pharmacologic considerations essential for all relevant pharmaceuticals. State-of-the-art diagnostic testing procedures help you ensure accurate diagnoses for all clinically relevant pathogens. Content reflects the expert insight and vast clinical experience of a panel of trusted authorities on small animal infectious diseases. Easy-to-use companion website provides convenient online access to additional images, tables, boxes, appendices, and references linked directly to original PubMed abstracts. Expanded coverage of zoonoses, zoonotic potential, and precautions helps you effectively monitor and treat zoonotic infections. Fully updated drug formulary reflects the most current pharmacokinetics, indications, contraindications, handling and administration guidelines, and dosage recommendations available. Updated content throughout the text details current diagnostic testing regimens and therapeutic and preventive considerations for all pathogens you're likely to encounter in the clinical setting. Special focus on disease incidence and susceptibility in traveling animals helps you alert animal owners to potential risks associated with pet travel.
Viruses And Human Disease
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Author : Ellen G. Strauss
language : en
Publisher: Elsevier
Release Date : 2007-09-21
Viruses And Human Disease written by Ellen G. Strauss and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-21 with Medical categories.
Completely revised and updated, the new edition of this groundbreaking text integrates basic virology with pathophysiological conditions to examine the connection between virology and human disease. Most virology textbooks focus on the molecular biology involved without adequate reference to physiology. This text focuses on viruses that infect humans, domestic animals and vertebrates and is based on extensive course notes from James Strauss’ virology class at the California Institute of Technology taught for over 30 years. Expertly depicting in color the molecular structure and replication of each virus, it provides an excellent overview for students and professionals interested in viruses as agents of human disease. Includes over 30% new material - virtually all of the figures and tables have been redrawn to include the latest information and the text has been extensively rewritten to include the most up-to-date information Includes a new chapter on emerging and reemerging viral diseases such as avian flu, SARS, the spread of West Nile virus across America, and the continuing spread of Nipah virus in Southeast Asia Further reading sections at the end of each chapter make it easy find key references World maps depicting the current distribution of existing and newly emerging viruses are also incorporated into the text
Equine Neurology
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Author : Martin Furr
language : en
Publisher: John Wiley & Sons
Release Date : 2015-04-09
Equine Neurology written by Martin Furr and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-09 with Medical categories.
Equine Neurology, Second Edition provides a fully updated new edition of the only equine-specific neurology book, with comprehensive, clinically oriented information. Offers a complete clinical reference to neurologic conditions in equine patients Takes a problem-based approach to present a clinically oriented perspective Presents new chapters on imaging the nervous system, neuronal physiology, sleep disorders, head shaking, differential diagnosis of muscle trembling and weakness, and cervical articular process joint disease Covers the basic principles of neurology, clinical topics such as the initial exam, differentials, and neuropathology, and specific conditions and disorders Includes access to a companion website offering video clips demonstrating presenting signs
Virus As Populations
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Author : Esteban Domingo
language : en
Publisher: Academic Press
Release Date : 2019-11-06
Virus As Populations written by Esteban Domingo and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-06 with Science categories.
Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included. The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere. Features current views on key steps in the origin of life and origins of viruses Includes examples relating ancestral features of viruses with their current adaptive capacity Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read Considers quasispecies as a framework to understand virus adaptability and disease processes
Pet Bird Diseases And Care
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Author : Indranil Samanta
language : en
Publisher: Springer
Release Date : 2017-02-24
Pet Bird Diseases And Care written by Indranil Samanta and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-24 with Science categories.
This book provides fundamental information on pet birds, menaces, and advances made in the diagnosis and treatment of menaces. It is the only book covering all species of pet birds, menaces and their individual management. The handful of related books available worldwide are largely outdated and focus on a single species or breed of pet bird. The book encompasses the history of bird keeping, common breeds of birds, their nutritional requirements, list of zoonotic diseases transmitted by birds and guideline for their prevention. It covers infectious, non-infectious clinical and metabolic diseases, and toxicity in detail with a special focus on the history of diseases, etiology, affected hosts, pathogenesis, clinical signs, diagnosis and treatment. Separate chapters detail relevant diagnostic techniques, management and care practices, including updated information. The book offers an invaluable guide for students and teachers in the field of (avian) veterinary medicine, scientists/research scholars working in related fields, and avian medicine practitioners, as well as all those progressive bird owners who want to know the basics of their care and management.