Modeling The Psychopathological Dimensions Of Schizophrenia
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Modeling The Psychopathological Dimensions Of Schizophrenia
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Author : Mikhail Pletnikov
language : en
Publisher: Academic Press
Release Date : 2015-11-05
Modeling The Psychopathological Dimensions Of Schizophrenia written by Mikhail Pletnikov and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-05 with Psychology categories.
Modeling the Psychopathological Dimensions of Schizophrenia: From Molecules to Behavior is the first book to offer a comprehensive review of the new theoretical, clinical, and basic research framework that considers psychotic illness as a group of dimensional representations of psychopathology rather than as traditional distinct categorical diagnoses. Psychotic illness, typified by schizophrenia, is a devastating condition increasingly recognized as a disorder of abnormal brain development and dysconnectivity. Its complex etiology involves both genetic and environmental factors, as well as the interplay among them. This book describes the current understanding of the clinical and pathological features of schizophrenia, with a particular focus on the evolving conceptualization of schizophrenia and related diagnostic categories of psychotic illness as combinations of dimensional abnormalities. It provides an overview of modern strategies for generating cellular and whole animal models of schizophrenia as well as detailed reviews of the specific experimental preparations and paradigms aimed at molecular, developmental, and brain-network mechanisms that are the underlying aspects of abnormal behavior and various aspects of schizophrenia. This groundbreaking book is an authoritative overview of the translational impact of emerging clinical insights on basic research approaches in schizophrenia that will advance the reader's understanding of the five major dimensions of psychopathology in schizophrenia and related psychoses and resolve the genetic and neurobiological underpinnings of these dimensions. - Includes reviews of animal models that capture the most recent insights into the etiology and pathogenetic mechanisms of schizophrenia, with an emphasis on the translational potential of these models - Contains a series of reviews of recently available cellular models for analysis of signaling pathways and gene expression, which complement behavioral neuroscience research in schizophrenia - Edited and authored by leading researchers in the field of schizophrenia and related psychoses
Cognitive Impairment In Schizophrenia
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Author : Philip D. Harvey
language : en
Publisher: Cambridge University Press
Release Date : 2013-01-24
Cognitive Impairment In Schizophrenia written by Philip D. Harvey and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-24 with Medical categories.
Although the precise mechanisms and pathways of schizophrenia remain something of a mystery, there is little dispute that cognitive deficits present as some of the clearest and most debilitating symptoms of the disease. This book describes the characteristics of cognitive deficits in schizophrenia, functional implications, the course of impairments, the genetic and biological contributions and reviews management options, including neuropsychological, psychological and pharmacological techniques. Chapters are written by leading experts in the field, in an accessible and highly informative style, ensuring the content is clinically relevant. State-of-the-art information about new developments in the treatment of related features of the illness, such as disability, is provided. The wide ranging focus of this volume will appeal to clinicians and academic researchers working with patients impaired by severe mental illness.
Re Visioning Psychiatry
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Author : Laurence J. Kirmayer
language : en
Publisher: Cambridge University Press
Release Date : 2015-07-29
Re Visioning Psychiatry written by Laurence J. Kirmayer and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-29 with Medical categories.
Revisioning Psychiatry brings together new perspectives on the causes and treatment of mental health problems. The contributors emphasize the importance of understanding experience and explore how the brain, the person, and the social world interact to give rise to mental health problems as well as resilience and recovery.
Psychotic Disorders
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Author : Carol A. Tamminga MD
language : en
Publisher: Oxford University Press
Release Date : 2020-10-20
Psychotic Disorders written by Carol A. Tamminga MD and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-20 with Medical categories.
Psychotic Disorders: Comprehensive Conceptualization and Treatments emphasizes a dimensional approach to psychosis--one of the most fascinating manifestations of altered brain behavior--that cuts across a broad array of psychiatric diagnoses from schizophrenia to affective psychosis and organic disorders like epilepsy and dementias. Written by an international roster of over seventy leading experts in the field, this volume comprehensively reviews, critiques, and integrates available knowledge on the etiology, mechanisms, and treatments of psychotic disorders, and outlines ways forward in both research and clinical practice towards more objective, mechanistically-based definitions of psychotic disorders. Chapters address topics such as psychosis phenomenology, biomarkers and treatments, the overlaps and interfaces between psychiatric disorders within the psychosis dimension, and novel disease definitions. Furthermore, the volume incorporates findings on potential mechanisms, bridges between various system levels (i.e., genetic, epigenetic, molecular and cellular, brain circuit and function, psychological, social, environmental and cultural) and their interactions, as well as the potential role in causation and/or mediation in psychotic disorders. Finally, the volume outlines a broad array of treatment approaches, from the readily available (e.g., psychopharmacology, various modalities of psychotherapy) to the experimental (e.g., cognitive interventions, neuromodulation). With a concluding section of forward perspectives conjecturing future directions and related challenges, this book aspires to stimulate new knowledge, generate novel frameworks, and carry new directions forward on psychotic disorders.
Schizophrenia Bulletin
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Author :
language : en
Publisher:
Release Date : 2013
Schizophrenia Bulletin written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Schizophrenia categories.
Schizophrenia Bulletin
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Author :
language : en
Publisher:
Release Date : 2005
Schizophrenia Bulletin written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Schizophrenia categories.
Search For The Causes Of Schizophrenia
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Author : Wagner F. Gattaz
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Search For The Causes Of Schizophrenia written by Wagner F. Gattaz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
This book comprises the conferences and discussions presented at the 4th sym posium on the SEARCH FOR THE CAUSES OF SCHIZOPHRENIA, which took place in Guaruja, Brazil, November 1998. This series of symposia started in 1986, on the occasion of the 600th anniversary of the University of Heidelberg, followed by two others in 1989 and 1993. From these meeting resulted three volumes that have been widely used as a reference for comprehensive reviews on the state of the art in schizophrenia research. They reflect the progresses result ing from the most relevant studies on the etiology of the disease. The spirit of the 4th "Search for the Causes" remains the same: again we gathered some of the most prominent researchers on schizophrenia to contrib ute not only with their own data, but also summing up the state of the art and the perspectives in their areas of work. The topics covered in 6 parts are Epide miology, Risk factors and antecedents, Genetics, Neuropathology and neuro chemistry, Brain imaging and function, and Treatment and rehabilitation. In this 4th volume were introduced in each topic a chapter on the "Balance of the Cen tury", to summarize what did we learn (and what we did not) in the last 100 years of schizophrenia research. We hope that this volume can help us to see how far we are in the Search for the Causes of Schizophrenia and how much further we still have to go before our problem can be solved.
Cumulated Index Medicus
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Author :
language : en
Publisher:
Release Date : 1991
Cumulated Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medicine categories.
Dimensional Psychopathology
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Author : Massimo Biondi
language : en
Publisher: Springer
Release Date : 2018-05-30
Dimensional Psychopathology written by Massimo Biondi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-30 with Medical categories.
This book presents an innovative approach to clinical assessment in psychiatry based on a number of psychopathological dimensions with a presumed underlying pathophysiology, that are related to fundamental phenomenological aspects and lie on a continuum from normality to pathology. It is described how the evaluation of these dimensions with a specific, validated rapid assessment instrument could easily integrate and enrich the classical diagnostic DSM-5 or ICD-10 assessment. The supplemental use of this dimensional approach can better capture the complexity underlying current categories of mental illness. The findings from a large patient sample suggest how this assessment could give a first glance at how variable and multifaceted the psychopathological components within a single diagnostic category can be, and thereby optimise diagnosis and treatment choices. Being short and easy to complete, this dimensional assessment can be done in a busy clinical setting, during an ordinary psychiatric visit, and in an acute clinical context, with limited effort by a minimally trained clinician. Therefore, it provides interesting and useful information without additional costs, and allows research work to be performed even in difficult settings.
Schizophrenia
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Author : Daniel R. Weinberger
language : en
Publisher: John Wiley & Sons
Release Date : 2011-07-13
Schizophrenia written by Daniel R. Weinberger and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-13 with Medical categories.
Schizophrenia is one of the most complex and disabling diseases to affect mankind. Relatively little is known about its nature and its origins, and available treatments are inadequate for most patients. As a result, there are inevitable controversies about what causes it, how to diagnose it, and how best to treat it. However, in the past decade, there has been an explosion of new research, with dramatic discoveries involving genetic etiology and epidemiological risk factors. There has also been a catalog of new drugs coming to market, and controversy about the relative advantages and disadvantages of newer compared with older therapies. In addition, developing technologies in genomics, molecular biology and neuroimaging provide streams of new information. This book represents a definitive, essential, and up-to-date reference text on schizophrenia. It extensively and critically digests and clarifies recent advances and places them within a clinical context. The Editors (one American and one British), highly respected clinical psychiatrists and researchers and acknowledged experts on schizophrenia, have again assembled an outstanding group of contributors from the USA, UK, Europe and Australia, It will be of value to practising psychiatrists and to trainees, as well as to clinical and neuroscience researchers interested in keeping up with this field or coming into it. The book consists of four sections: descriptive aspects, biological aspects, physical treatments, and psychological and social aspects. It reviews the theoretical controversies over symptomatology, classification and aetiology (particularly pertinent as DSM-V is being developed), the relationship of schizophrenia to the other psychoses, the significance of positive and negative symptoms and pre-morbid personality. It describes a variety of approaches to integrating the vast research data about schizophrenia, including neurodevelopmental, genetic, pharmacological, brain imaging and psychological findings. The biological treatment section reviews the comparative efficacy of various drugs, the management of drug-resistant patients and both neurological and metabolic complications. The final section looks at psychological therapies, social outcomes, and the economics of schizophrenia. Highly Commended in the Psychiatry section of the 2012 BMA Book Awards.