Borrelia Burgdorferi
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Borrelia Burgdorferi
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Author : Leona Gilbert
language : en
Publisher: Springer Nature
Release Date : 2024-01-02
Borrelia Burgdorferi written by Leona Gilbert and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-02 with Science categories.
This volume covers the latest advancements and techniques used to understand the fastidious bacterium, Borrelia burgdorferi, and its significance in infectious disorders by combining both conventional and cutting-edge approaches. This book covers diverse topics, including direct detection, diagnostic methods, immune response analysis, alternative model systems, advanced proteomics, social media analysis, and clinical research. It also discusses unconventional wet lab research such as content analysis, the use of ChatGPT, clinical algorithms for chronic Lyme, establishment of a pregnancy Lyme disease biobank, and investigates Lyme in pregnant women. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Borrelia burgdorferi: Methods and Protocols encompasses a wide range of techniques and caters to scientists from various disciplines and career stages, such as cell and molecular biologists, statisticians, and clinical researchers.
Lyme Borreliosis
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Author : John S. Axford
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Lyme Borreliosis written by John S. Axford and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Lyme Borreliosis is a worldwide infectious disease causing a multisystem illness with considerable morbidity, particularly in North America and Europe. The causative agent is the spirochaete Borrelia burgdorferi, which is usually transmitted by the ixodid tick from animal reservoirs. This book is formed by contributions from the Second European Symposium on Lyme Borreliosis, held at St George's Hospital Medical School, London in 1993, which reviewed the current state of knowledge of the condition with regard to clinical manifestations, diagnosis, treatment, ecology, epidemiology, biology and immunopathogenesis. In this book, important data is reviewed concerning the clinical manifestations of Lyme Borreliosis. It seems that strain variation of the spirochaete is the main cause of regional differences seen in the clinical presentation of patients. One striking example of this, is the relatively high incidence of Lyme arthritis in the USA and apparent rarity of this manifestion in some areas of Europe. These important studies open the way for exciting new research that focuses on the immunological and molecular mechanisms that result in disease. A full insight into the ecology of Borrelia burgdorferi is essential to a balanced understanding of the disease and a number of excellent reviews on this subject are included. Significant advances with regard to the biology of Borrelia burgdorjeri and the immunopathogenic mechanisms that result in disease have been made, enabling the role of the Band T lymphocytes in disease to be established and the development of sophisticated phenotyping methods, improved diagnostic tests and effective vaccines.
Lyme Borreliosis
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Author : J. Gray
language : en
Publisher: CABI
Release Date : 2002-10-04
Lyme Borreliosis written by J. Gray and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-10-04 with Borrelia burgdorferi categories.
Lyme borreliosis commonly known as lyme disease is now acknowledged as the most highly prevalent arthropod-borne human disease in northern temperate regions of the world. This book describes the basic characteristics of the disease, the biology of the pathogens in their vectors and vertebrate hosts, their ecology in different regions of the world and the global epidemiology of the disease. The final chapters address the prevention and control measures that have resulted from this knowledge.
Lyme Disease Recent Advances And Perspectives
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Author : Tanja Petnicki-Ocwieja
language : en
Publisher: Frontiers Media SA
Release Date : 2015-08-08
Lyme Disease Recent Advances And Perspectives written by Tanja Petnicki-Ocwieja and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-08 with Infectious and parasitic diseases categories.
The interplay between host and pathogen is a complex co-evolutionary battle of surveillance and evasion. The pathogen continuously develops mechanisms to subvert the immune response in order to establish infection while the immune system responds with novel mechanisms of detection. Because the majority of Lyme disease pathology is due to an over-exuberant immune response, much research in Borrelia burgdorferi pathogenesis has been devoted to understanding the mammalian host response to the bacterium. Immunological studies continue to be an active area of research employing emerging techniques, such as intra-vital imaging. These studies have furthered our understanding of inflammatory processes during long-term infection and provided some surprising insights, such as the continued presence of bacterial products after clearance. The field of Lyme disease has long debated the etiology of long-term inflammation and recent studies in the murine host have shed light on relevant cell types and inflammatory mediators that participate in the pathology of Lyme arthritis. Live imaging and bioluminescent studies have allowed for a novel view of the bacterial life cycle, including the tick mid-gut, tick-to-mammal transmission and dissemination throughout a mouse. A number of tick and bacterial proteins have been shown to participate in the completion of the enzootic cycle. Novel mechanisms of gene regulation are continuously being identified. However, B. burgdorferi lacks many traditional virulence factors, such as toxins or specialized secretion systems. Many genes in the B. burgdorferi genome have no known homolog in other bacteria. Therefore, studies focusing on host-pathogen interactions have therefore been limited by an incomplete understanding of the repertoire of bacterial virulence factors. Questions such as how the pathogen causes disease, colonizes the tick and evades host immune-surveillance have been difficult to address. Genetic studies involving single gene deletions have identified a number of important bacterial proteins, but a large-scale genomics approach to identify virulence factors has not been attempted until recently. The generation of a site-directed mutagenesis library is an important step towards a detailed analysis of the B. burgdorferi genome and pathogenome. Using this library, high-throughput genomic studies, utilizing techniques such as massively parallel sequencing have been promising and could be used to identify novel virulence determinants of disease in the mammalian host or persistence in the tick vector. Continued research on this unique pathogen and its specific interaction with host and vector may have far reaching consequences and provide insights for diverse disciplines including ecology, infectious disease, and immunology. Here, several reviews will discuss the most recent advances and future studies to be undertaken in the field of B. burgdorferi biology.
Lyme Disease 2nd Edition
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Author : John J Halperin
language : en
Publisher: CABI
Release Date : 2018-08-20
Lyme Disease 2nd Edition written by John J Halperin and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-20 with Medical categories.
This new edition of Lyme Disease provides up-to-date evidence-based research and covers the significant advances in our understanding of the disorders referred to as Lyme disease or Lyme borreliosis. This book explores the causative organism, its requisite ecosystem, disease epidemiology, host-Borrelia interactions, diagnostic testing, clinical manifestations, therapeutic options, the role of host immunity on pathogenesis and long term prognosis. The authors provide balanced perspectives on all aspects of Lyme disease and explicitly review both the basic biology of the infection and practical clinical aspects. This new edition includes new borrelial pathogens that have been identified (B. miyamotoi, B. mayonii and B. bavariensis among others). Provides updated information on the molecular biology of the organism, neuroborreliosis, and the role of the C6 peptide in diagnosis. Discusses the controversies about 'chronic Lyme disease', post Lyme disease syndrome and other ongoing but non-specific symptoms that have been attributed to this infection. As the endemic footprint of Lyme disease continues to grow, this book provides a broad and detailed guide for clinicians and researchers involved with the diagnosis and treatment of the condition. Covering biology, epidemiology and therapeutics, it is also essential reading for students of global health and infectious disease.
Advances In Borrelia Burgdorferi Group Research And Treatment 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09
Advances In Borrelia Burgdorferi Group Research And Treatment 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Medical categories.
Advances in Borrelia burgdorferi Group Research and Treatment: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Borrelia burgdorferi Group in a compact format. The editors have built Advances in Borrelia burgdorferi Group Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Borrelia burgdorferi Group in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Borrelia burgdorferi Group Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Advances In Borrelia Burgdorferi Group Research And Treatment 2013 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2013-06-21
Advances In Borrelia Burgdorferi Group Research And Treatment 2013 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-21 with Medical categories.
Advances in Borrelia burgdorferi Group Research and Treatment: 2013 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about ZZZAdditional Research in a compact format. The editors have built Advances in Borrelia burgdorferi Group Research and Treatment: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Borrelia burgdorferi Group Research and Treatment: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Advances In Borrelia Burgdorferi Group Research And Treatment 2012 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-12-26
Advances In Borrelia Burgdorferi Group Research And Treatment 2012 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-26 with Medical categories.
Advances in Borrelia burgdorferi Group Research and Treatment / 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Borrelia burgdorferi Group in a concise format. The editors have built Advances in Borrelia burgdorferi Group Research and Treatment / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Borrelia burgdorferi Group in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Borrelia burgdorferi Group Research and Treatment / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Lyme Disease Update
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Author : Marcus Cohen
language : en
Publisher:
Release Date : 2004
Lyme Disease Update written by Marcus Cohen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Lyme disease categories.
Lyme Disease Diagnosis And Treatment
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Author : Ava Madison
language : en
Publisher:
Release Date : 2015-03-26
Lyme Disease Diagnosis And Treatment written by Ava Madison and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-26 with Lyme disease categories.
Lyme disease, also called Lyme borreliosis, is an emerging infectious disease. It is caused by Borrelia burgdorferi (Bb) bacteria belonging to the genus Borrelia. This book contains in-depth knowledge about the molecular biology of the disease agent i.e. the Borrelia burgdorferi bacteria. It has been written by professionals of this field and has been compiled according to the requirements of researchers, advanced students of biology, molecular biology, and molecular genetics of the microorganism. Infectious disease experts and people in other areas interested in learning more about Lyme borreliosis will find this book beneficial. Some of the topics discussed in the book are the molecular biology of the Lyme disease agent, zoonotic peculiarities of Bb, advancement in Bb antibody testing, the serology diagnostic schemes in Bb, discovering Lyme disease in ticks and dogs, adaptation to glucosamine starvation in Bb, and porins in the genus Borrelia.