Bradykinin Antagonists
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Bradykinin Antagonists
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Author : Ronald M. Burch
language : en
Publisher: Marcel Dekker
Release Date : 1991
Bradykinin Antagonists written by Ronald M. Burch and has been published by Marcel Dekker this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.
Since 1985, when John Stewart and Ray Vavrek reported the first bradykinin analogs with antagonist activity at the B2 bradykinin receptor, several of the antagonists have been extensively used in studies of bradykinin receptor subtypes and of the role of bradykinin in blood pressure regulation, infl
Molecular Biology And Pharmacology Of Bradykinin Receptors
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Author : Ronald M. Burch
language : en
Publisher: R. G. Landes
Release Date : 1993
Molecular Biology And Pharmacology Of Bradykinin Receptors written by Ronald M. Burch and has been published by R. G. Landes this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Bradykinin categories.
Bradykinin Receptors Advances In Research And Application 2012 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-12-26
Bradykinin Receptors Advances In Research And Application 2012 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-26 with Medical categories.
Bradykinin Receptors—Advances in Research and Application: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Bradykinin Receptors in a compact format. The editors have built Bradykinin Receptors—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Bradykinin Receptors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Bradykinin Receptors—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
The Kinin System
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Author : Stephen G. Farmer
language : en
Publisher: Academic Press
Release Date : 1997-04-01
The Kinin System written by Stephen G. Farmer and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-04-01 with Medical categories.
Bradykinin is a type of plasma hormone that causes blood vessels to dilate, resulting in a drop in blood pressure, the contraction of muscles in the lungs, intestines, and uterus, and pain. The Kinin System reviews the molecular biology of the kinins through their roles in a complex array of inflammatory conditions such as asthma, GI disease, cardiovascular complaints and examines the future therapeutic opportunities. From the prepublication reviews:"A delicious masterpiece."--Chef's DigestThe Kinin System is a comprehensive, timely book covering all aspects of the kinin system from its disocvery to the pathophysiology, pharmacology, and molecular biology of the mechanisms regulating kinin production to kinin receptors in health and disease. The authors take a refreshingly different view of the kinin system than previous books on the subject. Several chapters contain new information on the gene expression, regulation, and cell surface presentation of kininogens and kallikreins, as well as new data, some of it from human studies, on the role of kinins in pain angiogenesis, tissue repair, sepsis, arthritis, asthma, allergic rhinits, myocardial ischemia, and other diseases. * * Offers new information on kinin reception, regulation of gene expression of receptors, and kinin-generating proteins.* Provides a distinctly immunopharmacological approach to the kinin system.* Reviews of the role of kinins in disease and inlcudes data from human studies.* Includes information that is fully up-to-date and comprehensive.
Kinins V
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Author : K. Abe
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-18
Kinins V written by K. Abe and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-18 with Medical categories.
The physiological and pathological significance of the kallikrein-kinin system was recently explored extensively, resulting in a rapid accumulation of information regarding their potential importance. This publication provides an integrated picture of the latest information on the kallikrein kinin system. It contains contributions from morphologists, geneticists, biochemists, pharmacologists, physiologists, and clinicians. The Fifth International Kinin Congress (Nov. 29-Dec. 3, 1987) provided a forum for the exchange of information and ideas on the kallikrein-kinin system. The participation of more than 350 scientists from 23 countries reflects the widespread interest and international scope of research activity in the physiological and pathological functions of the kallikrein-kinin system. A total of 275 papers including posters were presented, attesting to the unquestioned success of this Congress. These proceedings, in two volumes, contain the collective studies presented, studies of high scientific standard that provoked stimulating and fruitful discussions. Also included in these volumes are the two plenary lectures presented by Dr. H.A. Margolius (USA) and Dr. S. Nakanishi (Japan). During the last decade our knowledge of the role of the kallikrein kinin system in health and disease has been greatly advanced by the develop ment of antagonists to bradykinin and the introduction to clinical practice of converting enzyme inhibitors. Symposia on converting enzyme and on recent advances in research on the kallikrein-kinin system are included in the proceedings.
Recent Developments In The Regulation Of Kinins
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Author : Jagdish N. Sharma
language : en
Publisher: Springer
Release Date : 2014-05-26
Recent Developments In The Regulation Of Kinins written by Jagdish N. Sharma and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-26 with Medical categories.
This volume presents key topics of current interest with regard to several pathophysiological conditions including (a) the basic and clinical aspects of bradykinin receptor antagonists, (b) the kallikrein-kinin pathways in hypertension and diabetes, (c) tissue kallikrein-kinin therapy for hypertension and organ damage, (d) the renal (tissue) kallikrein-kinin system in the kidney and novel potential drugs for salt-sensitive hypertension, (e) the kallikrein-kinin system in diabetes retinopathy, and (f) genetic manipulation and genetic variation of the kallikrein-kinin system and their impacts on cardiovascular and renal disease. Written by internationally reputed scientists, the book provides an essential overview of the latest developments in the field of kinin research, making it a valuable asset for endocrinologists, nephrologists, cardiologists, pharmacologists, physiologists, ophthalmologists and rheumatologists. Furthermore, it is also intended for postgraduate students in the fields of medicine, pharmacy, physiology and pharmacology, and those working at research organizations.
Bradykinin And Related Kinins
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Author : F. Sicuteri
language : en
Publisher: Springer
Release Date : 1970
Bradykinin And Related Kinins written by F. Sicuteri and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1970 with Science categories.
Thus, new light is shed on basic problems involving the pathology of man as shock, angioneurotic edema, uratic arthritis, intracranial hemorrhage, and acute local and general reactions to thermal, mechanical and infectious assaults. It is with a certain degree of emotion that we now reconsider those terms and phenomena we were accustomed to seeing only from a cold biochemical point of view, such as the Hageman factor, the kallikrein inhibitor, and the permeability factor, under the warm light shed by the sufferings of man. This warmth, typical of human investigation, homogenized by the severity of experimental research, has contributed in making the scientific sessions more lively, and, above all, in creating the spontaneous and friendly atmosphere prevailing at Fiesole.
Angiotensin Ii Receptor Antagonists
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Author : Mancia Giuseppe
language : en
Publisher: CRC Press
Release Date : 2000-07-03
Angiotensin Ii Receptor Antagonists written by Mancia Giuseppe and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-07-03 with Medical categories.
Since angiotensin II is one of the most potent vasoconstrictors and an important stimulus for the secretion of aldosterone from the adrenal gland, the development of angiotensin II inhibitors is an important step in regulating blood pressure. This class of drug is well-tolerated by patients and these drugs have the added advantage over ACE inhibitors in that they are not associated with cough. Because most drugs can be given once daily and, like ACE inhibitors, they have a useful additive hypotensive effect in combination with diuretics, they are a welcome therapeutic tool in the treatment of hypertension.
Ace Inhibitors
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Author : Pedro D'Orléans-Juste
language : en
Publisher: Birkhäuser
Release Date : 2012-12-06
Ace Inhibitors written by Pedro D'Orléans-Juste and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Angiotensin converting enzyme inhibitors (ACEI) represent the first class of antihypertensive agents that was designed and developed on the basis of a well-defined physiopathological axis of arterial hypertension, a vascular dis order that is now becoming one of the major causes of morbidity/mortality, not only in developed societies but also in the highly populated developing coun tries [1]. CAPTOPRIL, the prototype of the "PRIL" family, which now comprises more than 40 molecule-species, was quite hazardous and the clinical develop ment almost failed when serious side-effects were reported in an alarmist fash ion in reputable scientific journals, such as the New England Journal of Medicine and Lancet. Squibb & Sons came very close to withdrawing CAPTOPRIL from clinical investigation [2]. However, after re-examination of the data obtained from different categories of patients and appropriate dose-adjustments, the clinical use of CAPTOPRIL turned out to be revolutionary. The prototype, as well as other members of the "PRIL" family became the starting point for numerous basic and clinical research programs, focusing on the interactions of ACEI with the kinin, endothelin, and nitric oxide systems, and the contribution of the receptors for AT I, AT 2, bradykinin Bland B , ETA and ET B to the pharmacological actions 2 of the respective peptides. This research activity led to the development of new pharmacological agents, such as the angiotensin receptor antagonists and, more recently, the neutral endopeptidase inhibitors. In the near future, bradykinin receptor antagonists also will be available to modulate ACEI phar macological actions.
Cerebrovascular Bibliography
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Author :
language : en
Publisher:
Release Date : 1968
Cerebrovascular Bibliography written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1968 with categories.