Brain Tumor Pathology Current Diagnostic Hotspots And Pitfalls

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Brain Tumor Pathology Current Diagnostic Hotspots And Pitfalls

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Author : Davide Schiffer
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-07-28

Brain Tumor Pathology Current Diagnostic Hotspots And Pitfalls written by Davide Schiffer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-07-28 with Medical categories.

Since Bailey and Cushing (1926), all brain tumor classifications have been called histogenetic. The nosographic position that the tumor types progressively acquired in the classification systems derived from the resemblance of tumor cells to those of the cytogenesis, modified whenever new information became available from different biological research fields and especially from molecular genetics. Classically, on the basis of the rough correspondence between the mature/immature aspect of tumor cells and the benign/malignant biological behavior of the tumors, the histological labels contained a prognostic significance. The supposed origin of the tumors was thus a factor for prognosis. Later on, with the concept of anaplasia (Cox, 1933; Kernohan et al., 1949) new criteria were introduced for establishing the malignancy grades of tumors. Immunohistochemistry and later molecular genetics further refined the prognostic diagnoses, substantially increasing the opportunities to recognize the cell origin of tumors, beside revealing the pathogenetic mechanisms. Prognoses became more accurate, as required by the greater and more targeted possibilities of therapy.

Brain Tumor Pathology Current Diagnostic Hotspots And Pitfalls

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Author : Davide Schiffer
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-03-09

Brain Tumor Pathology Current Diagnostic Hotspots And Pitfalls written by Davide Schiffer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-09 with Medical categories.

This book is not a treatise on brain tumor pathology and nosography. It has been conceived as a help to pathologists, neuropathologists and neuro-oncologists in confronting everyday problems arising in the diagnostics of brain tumors. Today, because of scientific advances in clinical diagnosis brain tumors are operated earlier, when they are still of reduced dimensions, and with new techniques and more frequently they undergo biopsy procedures. As a consequence, surgical samples for diagnosis are of a smaller size. On the other hand, the recourse to therapies ever more selective require more and more precise identification of tumor types and grades and quite often reliance must be placed on a limited number of cells, as tumor morphological patterns are no longer available. The ever greater precision leads to an increased risk of a flawed diagnosis. The book aims to illustrate the pitfalls most frequently encountered today in the practical activity of diagnosis and also of prognosis. The initial chapters cover the distinction between infiltrating tumors and normal nervous tissue, between diffuse astrocytoma and oligodendroglioma and the identification of the malignant variant of some tumor types. Moreover, in the pathology of brain tumors, some biological processes are active which show a development over the course of time, such that in surgical samples they cannot be recognized as a whole, but only from the occurrence of limited and partial aspects. Invasion modalities, angiogenesis and apoptosis fall in this category and are discussed not in an exhaustive manner, but as stages or phases of the processes identified in the tissue. The figures do not seek to illustrate the characteristic aspects of the tumors, but only the points under discussion.This book is the result of many years of personal experience in the diagnosis of brain tumors as well as of discussions with neurosurgeons and neuro-oncologists and it aspires to contribute to solving emerging everyday problems.

Forensic Neuropathology

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Author : Jan E. Leestma
language : en
Publisher: CRC Press
Release Date : 2008-10-14

Forensic Neuropathology written by Jan E. Leestma and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-10-14 with Law categories.

Over the past 30 years, as both forensic pathology and neuropathology have grown in sophistication, the two specialties have forged a heightened level of interaction. Reflecting the vast increase in knowledge and scientific progress in the past two decades, Forensic Neuropathology, Second Edition examines the new developments that have arisen since

Evolution Of The Molecular Biology Of Brain Tumors And The Therapeutic Implications

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Author : Terry Lichtor
language : en
Publisher: BoD – Books on Demand
Release Date : 2013-02-27

Evolution Of The Molecular Biology Of Brain Tumors And The Therapeutic Implications written by Terry Lichtor and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-27 with Medical categories.

A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years. In particular recent new avenues regarding the role of stem cells and microRNAs along with further understanding of the importance of angiogenesis, immunotherapy and explanations for the resistance of the tumors to chemotherapeutic agents and radiation therapy has been developed. It is hopeful that this new information will lead to efficacious treatment strategies for these tumors which remain a challenge. In this book a review of the latest information on these topics along with a variety of new therapeutic treatment strategies with an emphasis on molecular targeted therapies is provided.

Tumors Of The Central Nervous System

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Author : Lee Roy Morgan
language : en
Publisher: BoD – Books on Demand
Release Date : 2014-06-11

Tumors Of The Central Nervous System written by Lee Roy Morgan and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-11 with Medical categories.

A novel concept that is reviewed and discussed in several chapters in the book alludes to the transport of drugs bound to red blood cells into the highly vascular CNS tumors - both primary and metastatic. Such a transport mechanism is unique and of significant therapeutic potential. It is hopeful that the novel information presented in this book will result in new approaches to the treatment CNS tumors.

Management Of Cns Tumors

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Author : Miklos Garami
language : en
Publisher: BoD – Books on Demand
Release Date : 2011-09-22

Management Of Cns Tumors written by Miklos Garami and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-22 with Medical categories.

Management of CNS Tumors is a selected review of Central Nervous System (CNS) tumors with particular emphasis on pathological classification and complex treatment algorithms for each common tumor type. Additional detailed information is provided on selected CNS tumor associated disorders.

The Little Black Book Of Neuropsychology

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Author : Mike R. Schoenberg
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-01-11

The Little Black Book Of Neuropsychology written by Mike R. Schoenberg and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-11 with Psychology categories.

From translating the patient’s medical records and test results to providing recommendations, the neuropsychological evaluation incorporates the science and practice of neuropsychology, neurology, and psychological sciences. The Little Black Book of Neuropsychology brings the practice and study of neuropsychology into concise step-by-step focus—without skimping on scientific quality. This one-of-a-kind assessment reference complements standard textbooks by outlining signs, symptoms, and complaints according to neuropsychological domain (such as memory, language, or executive function), with descriptions of possible deficits involved, inpatient and outpatient assessment methods, and possible etiologies. Additional chapters offer a more traditional approach to evaluation, discussing specific neurological disorders and diseases in terms of their clinical features, neuroanatomical correlates, and assessment and treatment considerations. Chapters in psychometrics provide for initial understanding of brain-behavior interpretation as well as more advanced principals for neuropsychology practice including new diagnostic concepts and analysis of change in performance over time. For the trainee, beginning clinician or seasoned expert, this user-friendly presentation incorporating ‘quick reference guides’ throughout which will add to the practice armentarium of beginning and seasoned clinicians alike. Key features of The Black Book of Neuropsychology: Concise framework for understanding the neuropsychological referral. Symptoms/syndromes presented in a handy outline format, with dozens of charts and tables. Review of basic neurobehavioral examination procedure. Attention to professional issues, including advances in psychometrics and diagnoses, including tables for reliable change for many commonly used tests. Special “Writing Reports like You Mean It” section and guidelines for answering referral questions. Includes appendices of practical information, including neuropsychological formulary. The Little Black Book of Neuropsychology is an indispensable resource for the range of practitioners and scientists interested in brain-behavior relationships. Particular emphasis is provided for trainees in neuropsychology and neuropsychologists. However, the easy to use format and concise presentation is likely to be of particular value to interns, residents, and fellows studying neurology, neurological surgery, psychiatry, and nurses. Finally, teachers of neuropsychological and neurological assessment may also find this book useful as a classroom text. "There is no other book in the field that covers the scope of material that is inside this comprehensive text. The work might be best summed up as being a clinical neuropsychology postdoctoral residency in a book, with the most up to date information available, so that it is also an indispensible book for practicing neuropsychologists in addition to students and residents...There is really no book like this available today. It skillfully brings together the most important foundationsof clinical neuropsychology with the 'nuts and bolts' of every facet of assessment. It also reminds the more weathered neuropsychologists among us of the essential value of neuropsychological assessment...the impact of the disease on the patient’s cognitive functioning and behavior may only be objectively quantified through a neuropsychological assessment." Arch Clin Neuropsychol (2011) first published online June 13, 2011 Read the full review acn.oxfordjournals.org

Clinical Mr Spectroscopy

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Author : Peter B. Barker
language : en
Publisher: Cambridge University Press
Release Date : 2010

Clinical Mr Spectroscopy written by Peter B. Barker and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.

Covers all MR spectroscopy techniques and their clinical applications in neurological disorders, malignancies and musculoskeletal diseases.

Neurooncology

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Author : Amit Agrawal
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-07-13

Neurooncology written by Amit Agrawal and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-13 with Medical categories.

The book contains the information of various aspects of newer developments and recent advances in the field of central nervous system (CNS) tumor molecular biology, tumor progression, clinical presentation, imaging and management. The authors from different reputed institutions shared their knowledge on this open access platform to disseminate their knowledge at global level. As it is obvious in the current text, the field of neurooncology is heterogeneous and under continuous development with addition of new knowledge and information on regular basis. The collective contributions from experts attempt to provide updates regarding ongoing research and developments pertaining to CNS tumor genetics and molecular aspects and their applied aspect in reference to patient management.

Forensic Neuropathology Third Edition

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Author : Jan E. Leestma
language : en
Publisher: CRC Press
Release Date : 2014-06-23

Forensic Neuropathology Third Edition written by Jan E. Leestma and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-23 with Law categories.

The field of forensic neuropathology covers such controversial topics as the effects of repeated brain trauma in football players and how babies probably cannot die from being shaken. Jan Leestma is one of the most respected voices in this area. A timely update to his classic reference, Forensic Neuropathology: Third Edition presents an encyclopedic exposition of neuropathological conditions that may have forensic import. Reflecting the latest research, this edition includes expanded sections on multiple trauma, one punch/one hit arterial injuries, and the physiology of respiratory control. It presents new perspectives and rules regarding expert testimony and evidence admissibility occasioned by Daubert and related Supreme Court cases. The book explores how these rulings affect forensic pathologists, neuropathologists, and other potential experts as well as how they interact with the legal system. Several chapters examine the mechanisms and pathophysiology of neuropathological conditions and discuss the biomechanical basis for neurological injury. Where possible, aging and dating methodology is included for various processes. More than 325 updated full-color illustrations complement the text along with diagrams, tables, and figures that illustrate the textual material and can be useful as exhibits in court. An extensive bibliography provides background information and facilitates further research.