Bronchopulmonary Dysplasia Past Current And Future Pathophysiologic Concepts And Their Contribution To Understanding Lung Disease
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Bronchopulmonary Dysplasia Past Current And Future Pathophysiologic Concepts And Their Contribution To Understanding Lung Disease
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Author : Anne Hilgendorff
language : en
Publisher: Frontiers Media SA
Release Date : 2022-12-29
Bronchopulmonary Dysplasia Past Current And Future Pathophysiologic Concepts And Their Contribution To Understanding Lung Disease written by Anne Hilgendorff and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-29 with Medical categories.
Studying neonatal Chronic Lung Disease in the preterm infant, also known as Bronchopulmonary Dysplasia, has led to pathophysiologic concepts which enable a more profound understanding of the disease and generate treatment strategies allowing for the improvement of structural and functional pulmonary outcome. Here, both clinical studies as well as animal models have cross-fertilized each other, translating the definition of clinical needs and the identification of important variables from bench to bedside and back. Elaborate animal models have been designed and refined following different aims reaching from the understanding of relevant pathways as well as the investigation of clinically meaningful treatment strategies. By the use of large study cohorts, significant relationships between risk factors and their confounders could be identified, impacting both research aims and clinical routine. First, following current topics in the field the research topic will enrich the knowledge and discussion concerning different pathophysiologic concepts by addressing the most important topics either by review articles or the publication of new and relevant original data. The invitation of outstanding researchers will provide a body of excellent data with respect to the endothelial, epithelial and mesenchymal cell compartment, the role of stem cells and the extracellular matrix. Furthermore, articles on long-term effects as well as the understanding of injury through hyperoxia and ventilation/stretch as well as infection and inflammation will cover the current concepts of injury imposed on the developing lung with relevance to the disease. With this overview, the current research topics in the field of BPD will be comprehensively covered. Second, in an area of expert`s opinion added to every chapter, we will follow our strong belief that our understanding of BPD pathophysiology can in the same time profit from input of other areas in lung research as well as enrich current concepts from research fields addressing further developmental as well as adult lung diseases. In order to better understand important aspects of BPD research as well as to question current concepts from a new perspective, the opening of different fields of lung research towards each other will be the second key focus of each article. In short, every chapter will i) focus on pathophysiologic models of the past, present and future that evolved to better understand BPD by the use of original data or as a review (Expert Review/Article) and ii) enlighten relevant parallels to other lung diseases by pointing out contributions where the field of BPD can contribute to the understanding of other pediatric and adult lung diseases or would benefit from the integration of concepts known in related fields of research (Expert Opinion).
Lung Development
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Author : Claude Gaultier
language : en
Publisher: Springer
Release Date : 2013-05-27
Lung Development written by Claude Gaultier and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-27 with Medical categories.
Knowledge about the mechanisms of lung development has been growing rapidly, especially with regard to cellular and molecular aspects of growth and differentiation. This authoritative international volume reviews key aspects of lung development in health and disease by providing a comprehensive review of the complex series of cellular and molecular interactions required for lung development. It covers such topics as pulmonary hypoplasia, effects of malnutrition, and pulmaonary angiogenesis. An indispensable reference for all those involved in studying or treating lung disease in neonates and children, the book offers a unique view of the development of this essential organ.
The Newborn Lung
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Author : Eduardo Bancalari
language : en
Publisher: Elsevier Health Sciences
Release Date : 2018-06-19
The Newborn Lung written by Eduardo Bancalari and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-19 with Medical categories.
Dr. Richard Polin’s Neonatology Questions and Controversies series highlights the most challenging aspects of neonatal care, offering trustworthy guidance on up-to-date diagnostic and treatment options in the field. In each volume, renowned experts address the clinical problems of greatest concern to today’s practitioners, helping you handle difficult practice issues and provide optimal, evidence-based care to every patient. Stay fully up to date in this fast-changing field with The Newborn Lung, 3rd Edition. The most current clinical information throughout, including key management strategies that may reduce some of the chronic sequelae of neonatal respiratory failure. New content on the role of microbiome in lung injury and lung development. Current coverage of non-invasive respiratory support, perinatal events and their influence on lung development and injury, cell-based lung therapy, automation of respiratory support, and oxygenation targeting in preterm infants. Consistent chapter organization to help you find information quickly and easily. The most authoritative advice available from world-class neonatologists who share their knowledge of new trends and developments in neonatal care. Purchase each volume individually, or get the entire 7-volume set! Gastroenterology and Nutrition Hematology, Immunology and Genetics Hemodynamics and Cardiology Infectious Disease and Pharmacology New Volume! Nephrology and Fluid/Electrolyte Physiology Neurology The Newborn Lung
Porth S Pathophysiology
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Author : Tommie L. Norris
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2023-12-20
Porth S Pathophysiology written by Tommie L. Norris and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-20 with Medical categories.
Trusted for more than 40 years and updated to reflect today’s nursing challenges, Porth’s Pathophysiology: Concepts of Altered Health States, 11th Edition, continues a legacy of excellence with a comprehensive, nursing-focused approach that instills a mastery of both the physical and psychological aspects of altered health. More approachable and inclusive than ever, this unique text clarifies complex ideas through diverse perspectives, the latest evidence-based information, and engaging in-text features and application exercises.
Pediatric And Neonatal Mechanical Ventilation
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Author : Peter C. Rimensberger
language : en
Publisher: Springer
Release Date : 2014-11-12
Pediatric And Neonatal Mechanical Ventilation written by Peter C. Rimensberger and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-12 with Medical categories.
Written by outstanding authorities from all over the world, this comprehensive new textbook on pediatric and neonatal ventilation puts the focus on the effective delivery of respiratory support to children, infants and newborns. In the early chapters, developmental issues concerning the respiratory system are considered, physiological and mechanical principles are introduced and airway management and conventional and alternative ventilation techniques are discussed. Thereafter, the rational use of mechanical ventilation in various pediatric and neonatal pathologies is explained, with the emphasis on a practical step-by-step approach. Respiratory monitoring and safety issues in ventilated patients are considered in detail, and many other topics of interest to the bedside clinician are covered, including the ethics of withdrawal of respiratory support and educational issues. Throughout, the text is complemented by numerous illustrations and key information is clearly summarized in tables and lists.
Preterm Birth
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2007-05-23
Preterm Birth written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-23 with Medical categories.
The increasing prevalence of preterm birth in the United States is a complex public health problem that requires multifaceted solutions. Preterm birth is a cluster of problems with a set of overlapping factors of influence. Its causes may include individual-level behavioral and psychosocial factors, sociodemographic and neighborhood characteristics, environmental exposure, medical conditions, infertility treatments, and biological factors. Many of these factors co-occur, particularly in those who are socioeconomically disadvantaged or who are members of racial and ethnic minority groups. While advances in perinatal and neonatal care have improved survival for preterm infants, those infants who do survive have a greater risk than infants born at term for developmental disabilities, health problems, and poor growth. The birth of a preterm infant can also bring considerable emotional and economic costs to families and have implications for public-sector services, such as health insurance, educational, and other social support systems. Preterm Birth assesses the problem with respect to both its causes and outcomes. This book addresses the need for research involving clinical, basic, behavioral, and social science disciplines. By defining and addressing the health and economic consequences of premature birth, this book will be of particular interest to health care professionals, public health officials, policy makers, professional associations and clinical, basic, behavioral, and social science researchers.
Fetal And Neonatal Lung Development
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Author : Alan H. Jobe
language : en
Publisher: Cambridge University Press
Release Date : 2016-04-18
Fetal And Neonatal Lung Development written by Alan H. Jobe and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-18 with Medical categories.
Lung disease affects more than 600 million people worldwide. While some of these lung diseases have an obvious developmental component, there is growing appreciation that processes and pathways critical for normal lung development are also important for postnatal tissue homeostasis and are dysregulated in lung disease. This book provides an authoritative review of fetal and neonatal lung development and is designed to provide a diverse group of scientists, spanning the basic to clinical research spectrum, with the latest developments on the cellular and molecular mechanisms of normal lung development and injury-repair processes, and how they are dysregulated in disease. The book covers genetics, omics, and systems biology as well as new imaging techniques that are transforming studies of lung development. The reader will learn where the field of lung development has been, where it is presently, and where it is going in order to improve outcomes for patients with common and rare lung diseases.
Keeping In Touch The Role Of Organelle Dynamics And Contacts In Health And Disease
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Author : Du Feng
language : en
Publisher: Frontiers Media SA
Release Date : 2021-09-23
Keeping In Touch The Role Of Organelle Dynamics And Contacts In Health And Disease written by Du Feng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-23 with Science categories.
Gregory S Pediatric Anesthesia
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Author : Dean B. Andropoulos
language : en
Publisher: John Wiley & Sons
Release Date : 2020-03-26
Gregory S Pediatric Anesthesia written by Dean B. Andropoulos and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-26 with Medical categories.
As the field pediatric anesthesia advances and expands, so too does the gamut of challenges that are faced by today’s anesthesiologists. Gregory’s Pediatric Anesthesia aims to fully prepare trainees and experienced professionals for modern practice by equipping them with the knowledge and cutting-edge techniques necessary to safely and successfully anesthetize children for a range of different surgeries and other procedures. Supporting their work with current data and evidence, the authors explore topics including basic principles, potential complications, and best practice, and illustrate their findings with detailed case studies that cover all major subspecialties. This essential new edition includes access to illustrative videos and features new and expanded sections, such as: Anesthesia for Spinal Surgery complications including postoperative blindness Robotic surgery for Pediatric Urological Procedures Anesthesia for Non-Cardiac Surgery in Patients with Congenital Heart Disease (new chapter) Extensive additional ultrasound images for regional anesthesia Neonatal Resuscitation The Pediatric Surgical Home and Enhanced Recovery after Surgery (new chapter) Now in its sixth edition, Gregory’s Pediatric Anesthesia continues to provide reliable and easy-to-follow guidance to all anesthesiologists caring for younger patients.
Sphingolipids In Disease
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Author : Erich Gulbins
language : en
Publisher: Springer
Release Date : 2015-05-20
Sphingolipids In Disease written by Erich Gulbins and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-20 with Medical categories.
Sphingolipids are lipid components of the plasma membrane of eukaryotic cells with an important function in signaling mechanisms in the cell. This book provides insight into the physiological and pathophysiological role of sphingolipids and in particular its derivative ceramide. The function of Sphingolipids in cell signaling with regard to infectious and lung diseases, cancer, cardiovascular diseases and neuropsychiatric disorders are described and treated in distinct parts. Together with Volume 215 from the same Editors, the collection represents a unique, comprehensive work on Sphingolipids, providing information on both: Sphingolipid basic biology as well as its important function in a (patho)physiological context. The book is written for scientists in pharmacology, biochemistry and cell biology with a focus on biomedical research as well as for clinicians in pharmacology, oncology, cardiology, neurology and infectious disease.