Keeping In Touch The Role Of Organelle Dynamics And Contacts In Health And Disease


Keeping In Touch The Role Of Organelle Dynamics And Contacts In Health And Disease
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Keeping In Touch The Role Of Organelle Dynamics And Contacts In Health And Disease


Keeping In Touch The Role Of Organelle Dynamics And Contacts In Health And Disease
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Author : Du Feng
language : en
Publisher: Frontiers Media SA
Release Date : 2021-09-23

Keeping In Touch The Role Of Organelle Dynamics And Contacts In Health And Disease written by Du Feng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-23 with Science categories.




The Dynamic Nature Of Mitochondria


The Dynamic Nature Of Mitochondria
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Author : Andreas S. Reichert
language : en
Publisher: CRC Press
Release Date : 2024-04-15

The Dynamic Nature Of Mitochondria written by Andreas S. Reichert and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-15 with Science categories.


Mitochondrial research has exploded over the last ~150 years. This book gives an amazing view on a conceptual change in our understanding of mitochondrial biology. It becomes clear that mitochondria are extremely dynamic in nature, controlling life at multiple levels. Mitochondria rule energy conversion, adapt cells well to changing stress and nutrient conditions, and regulate many cellular processes including immunity. The dynamic nature of mitochondria occurs at an intramitochondrial level but also includes its ability to interact with other organelles and to modulate multiple signalling pathways. It is thus not surprising that alterations or inabilities to ensure this dynamic behaviour is linked to ageing and human diseases. The following sections give an updated view on mitochondria: Mitochondrial ultrastructure: molecular mechanisms shaping the inner membrane Mitochondrial cristae and lipid dynamics: from super-resolution microscopy to lipid-OXPHOS interplay Mitochondrial control of cellular homeostasis: from redox signalling to interorganellar contact sites Mitochondria in health and disease: from mtDNA release to Complex I assembly Advanced methods in mitochondrial biology and metabolism research Integrative view on mitochondrial research and outlook The field of mitochondrial research has always been full of surprises and has helped science to advance tremendously. It developed hand in hand with landmark developments in technology, such as super-resolution microscopy (nanoscopy), and is currently influencing an increasing number of scientific disciplines. There is still much ‘new’ to find out about this ‘old’ organelle and I think that you can find interesting and also unexpected aspects of mitochondrial biology in this book. I hope the book will enhance your scientific curiosity and inspire your own research.



Computational Systems Biology Of Synaptic Plasticity Modelling Of Biochemical Pathways Related To Memory Formation And Impairement


Computational Systems Biology Of Synaptic Plasticity Modelling Of Biochemical Pathways Related To Memory Formation And Impairement
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Author : Kulasiri Don
language : en
Publisher: #N/A
Release Date : 2017-06-09

Computational Systems Biology Of Synaptic Plasticity Modelling Of Biochemical Pathways Related To Memory Formation And Impairement written by Kulasiri Don and has been published by #N/A this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-09 with Computers categories.


This book demonstrates the power of mathematical thinking in understanding the biological complexity that exists within the brain. It looks at the latest research on modelling of biochemical pathways within synapses, and provides a clear background for the study of mathematical models related to systems biology. Discussion then focusses on developments in computational models based on networks linked to synaptic plasticity. The models are used to understand memory formation and impairment and they provide a mathematical basis for memory research. Computational Systems Biology of Synaptic Plasticity is a valuable source of knowledge to postgraduate students and researchers in computational systems biology, and as a reference book for various techniques that are needed in modelling biological processes.



Mitochondrial Communication In Physiology Disease And Aging


Mitochondrial Communication In Physiology Disease And Aging
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Author : Nuno Raimundo
language : en
Publisher: Frontiers Media SA
Release Date : 2019-08-20

Mitochondrial Communication In Physiology Disease And Aging written by Nuno Raimundo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-20 with categories.


This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.



Organelle Contact Sites


Organelle Contact Sites
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Author : Mitsuo Tagaya
language : en
Publisher: Springer
Release Date : 2017-08-16

Organelle Contact Sites written by Mitsuo Tagaya and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-16 with Science categories.


This book provides the first comprehensive coverage of the quickly evolving research field of membrane contact sites (MCS). A total of 16 chapters explain their organization and role and unveil the significance of MCS for various diseases. MCS, the intracellular structures where organellar membranes come in close contact with one another, mediate the exchange of proteins, lipids, and ions. Via these functions, MCS are critical for the survival and the growth of the cell. Owing to that central role in the functioning of cells, MCS dysfunctions lead to important defects of human physiology, influence viral and bacterial infection, and cause disease such as inflammation, type II diabetes, neurodegenerative disorders, and cancer. To approach such a multifaceted topic, this volume assembles a series of chapters dealing with the full array of research about MCS and their respective roles for diseases. Most chapters also introduce the history and the state of the art of MCS research, which will initiate discussion points for the respective types of MCS for years to come. This work will appeal to all cell biologists as well as researchers on diseases that are impacted by MCS dysfunction. Additionally, it will stimulate graduate students and postdocs who will energize, drive, and develop the research field in the near future.



Severe Asthma


Severe Asthma
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Author : Yong Chul Lee
language : en
Publisher: Springer
Release Date : 2017-10-30

Severe Asthma written by Yong Chul Lee and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-30 with Medical categories.


This book presents state of the art knowledge on severe asthma with the aim of providing readers with a clear understanding of, first, the heterogeneity of the condition and of patients’ symptom profiles and responses to therapy and, second, the future implications of this heterogeneity for individualized patient care. After an opening section that offers an overview of severe asthma, including its clinical significance, the pathogenesis, available diagnostic approaches, and treatment options are described in detail. The sections on diagnosis and treatment cover the role of biomarkers, the use of radiologic diagnostic modalities, and both pharmacologic and non-pharmacologic therapies, including emerging options that will address hitherto unmet needs of patients. The outcomes of cutting-edge preclinical and clinical research are carefully documented and numerous useful tips provided on patient management. The inclusion of many informative schematic figures will assist readers in grasping the contents easily. The book will be of high value for medical students, researchers, general physicians, specialists, and paramedical staff.



Nonvesicular Transport


Nonvesicular Transport
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Author : Stephen S. Rothman
language : en
Publisher: Wiley-Interscience
Release Date : 1985

Nonvesicular Transport written by Stephen S. Rothman and has been published by Wiley-Interscience this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Science categories.


This book presents a range of articles on varied topics that consider evidence for the existence of nonvesicular transport for processes that have generally been considered to be carried out by means of vesicle mechanisms, particularly for the movement of proteins and neurotransmitters across membranes. The contributors base their hypotheses on knowledge of the kinetic, thermodynamic, and compartmental characteristics of a process in real space-time, independent of specific models that attempt to explain it.



Molecular Biology Of The Cell


Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002

Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.




The Cell In Development And Inheritance


The Cell In Development And Inheritance
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Author : Edmund Beecher Wilson
language : en
Publisher:
Release Date : 1896

The Cell In Development And Inheritance written by Edmund Beecher Wilson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1896 with Cells categories.




Autophagy And Signaling


Autophagy And Signaling
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Author : Taylor & Francis Group
language : en
Publisher: CRC Press
Release Date : 2021-03-30

Autophagy And Signaling written by Taylor & Francis Group and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-30 with categories.


Autophagy and Signaling is an up-to-date overview of the many signaling pathways regulating autophagy in response to different cellular needs. Discussion includes the status and future directions of autophagy signaling research with respect to different aspects of health and disease. These include the roles of autophagy in regulating cell fate, immune response and host defense, nutrient sensing and metabolism, neural functions and homeostasis. The mechanisms and significance of cross-talk between autophagy and other cellular processes is also explored. Lastly, alterations in autophagy observed in aging and age-related pathologies are described.