Caenorhabditis Elegans
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C Elegans Ii
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Author : Donald L. Riddle
language : en
Publisher: Firefly Books
Release Date : 1997
C Elegans Ii written by Donald L. Riddle and has been published by Firefly Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Medical categories.
Defines the current status of research in the genetics, anatomy, and development of the nematode C. elegans, providing a detailed molecular explanation of how development is regulated and how the nervous system specifies varied aspects of behavior. Contains sections on the genome, development, neural networks and behavior, and life history and evolution. Appendices offer genetic nomenclature, a list of laboratory strain and allele designations, skeleton genetic maps, a list of characterized genes, a table of neurotransmitter assignments for specific neurons, and information on codon usage. Includes bandw photos. For researchers in worm studies, as well as the wider community of researchers in cell and molecular biology. Annotation copyrighted by Book News, Inc., Portland, OR
Caenorhabditis Elegans Cell Biology And Physiology
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Author : Joel Rothman
language : en
Publisher: Academic Press
Release Date : 2012-01-16
Caenorhabditis Elegans Cell Biology And Physiology written by Joel Rothman and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-16 with Medical categories.
The second part of an updated edition of the classic Methods in Cell Biology, Volume 48, this book emphasizes diverse methods and technologies needed to investigate C. elegans, both as an integrated organism and as a model system for research inquiries in cell, developmental, and molecular biology, as well as in genetics and pharmacology. By directing its audience to tried-and-true and cutting-edge recipes for research, this comprehensive collection is intended to guide investigators of C. elegans for years to come. Diverse, up-to-date techniques covered will be useful to the broadening community of C. elegans researchers for years to come Chapters written by leaders in the field Tried and true methods deliver busy researchers a one-stop compendium of essential protocols
The Nematode Caenorhabditis Elegans
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Author : William Barry Wood
language : en
Publisher:
Release Date : 1988
The Nematode Caenorhabditis Elegans written by William Barry Wood and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Science categories.
C Elegans
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Author : Ian A. Hope
language : en
Publisher: OUP Oxford
Release Date : 1999-12-09
C Elegans written by Ian A. Hope and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-12-09 with Science categories.
Caenorhabditis Elegans has been a popular model organism for biological research for over thirty years and has been used to investigate many aspects of animal development, for example apoptosis, the Hox genes, signal transduction pathways, and the development of the nervous system. It has recently taken on new importance with the publication of the entire genome sequence in 1998. The first chapter gives all the basic information on C. elegans required to use it: it's natural history, anatomy, life cycle, development, and evolution. Information on how to obtain, grow, and maintain C. elegans for use as a model system is given in Chapter 4. Chapters 2 and 3 describe the genome project and show how to use genome sequence information by searching the database for homologues using different search methods and then how to analyse the search data. The next chapter gives the essential practical details of transformation and common uses for the technique. Chapter 6 covers reverse genetics and describes strategies for gene inactivation that are known to work in C elegans: epigenetic inactivation and mutational germ line inactivation. Chapter 7 is designed to help the user analyse phenotype by microscopy and includes Normaski, fluorescence, 4-dimensional, and electron microscopy. Techniques for studying the neurobiology of C. elegans are given in chapter 8. Chapter 9 describes the three commonly used approaches for studying gene expression and Chapter 10 deals with the common methods of molecular biology essential for gene characterization. C. elegans is not the ideal organism for biochemical studies, but chapter 11 describes several procedures for producing biochemically useful quantities of pure tissues. The final chapter is about conventional genetics and details the standard procedures for selfing and crossing; mutagenesis and mutant screening; characterization of mutants; gene mapping; temperature-shift experiments and mosaic analysis. Caenorhabditis Elegans: A Practical Approach will therefore provide all the background information necessary for use of C. elegans as a model system.
Caenorhabditis Elegans
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Author :
language : en
Publisher: Academic Press
Release Date : 2011
Caenorhabditis Elegans written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Caenorhabditis elegans categories.
Caenorhabditis Elegans
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Author : Henry F. Epstein
language : en
Publisher: Academic Press
Release Date : 1995
Caenorhabditis Elegans written by Henry F. Epstein and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Caenorhabditis elegans categories.
The first of its kind, this laboratory handbook emphasizes diverse methods and technologies needed to investigate C. elegans, both as an integrated organism and as a model system for research inquiries in cell, developmental, and molecular biology, as well as in genetics and pharmacology. Four primary sections--Genetic and Culture Methods, Neurobiology, Cell and Molecular Biology, and Genomics and Informatics--reflect the cross-disciplinary nature of C. elegans research. Because C. elegans is a simple and malleable organism with a small genome and few cell types, it provides an elegant demonstr.
C Elegans
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Author : Kevin Strange
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-05
C Elegans written by Kevin Strange and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-05 with Medical categories.
Molecular biology has driven a powerful reductionist, or “molecule-c- tric,” approach to biological research in the last half of the 20th century. Red- tionism is the attempt to explain complex phenomena by defining the functional properties of the individual components of the system. Bloom (1) has referred to the post-genome sequencing era as the end of “naïve reductionism. ” Red- tionist methods will continue to be an essential element of all biological research efforts, but “naïve reductionism,” the belief that reductionism alone can lead to a complete understanding of living organisms, is not tenable. Organisms are clearly much more than the sum of their parts, and the behavior of complex physiological processes cannot be understood simply by knowing how the parts work in isolation. Systems biology has emerged in the wake of genome sequencing as the s- cessor to reductionism (2–5). The “systems” of systems biology are defined over a wide span of complexity ranging from two macromolecules that interact to carry out a specific task to whole organisms. Systems biology is integrative and seeks to understand and predict the behavior or “emergent” properties of complex, multicomponent biological processes. A systems-level characteri- tion of a biological process addresses the following three main questions: (1) What are the parts of the system (i. e.
C Elegans Atlas
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Author : David H. Hall
language : en
Publisher: CSHL Press
Release Date : 2008
C Elegans Atlas written by David H. Hall and has been published by CSHL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Caenorhabditis elegans categories.
Derived from the acclaimed online “WormAtlas,†C. elegansAtlas is a large-format, full-color atlas of the hermaphroditic form of the model organism C. elegans, known affectionately as “the worm†by workers in the field. Prepared by the editors of the WormAtlas Consortium, David H. Hall and Zeynep F. Altun, this book combines explanatory text with copious, labeled, color illustrations and electron micrographs of the major body systems of C. elegans. Also included are electron microscopy cross sections of the worm. This laboratory reference is essential for the working worm biologist, at the bench and at the microscope, and provides a superb companion to the C. elegansII monograph. It is also a valuable tool for investigators in the fields of developmental biology, neurobiology, reproductive biology, gene expression, and molecular biology.
The Neurobiology Of C Elegans
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Author :
language : en
Publisher: Elsevier
Release Date : 2006-02-02
The Neurobiology Of C Elegans written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-02-02 with Science categories.
The Neurobiology of C. elegans assembles together a series of chapters describing the progress researchers have made toward solving some of the major problems in neurobiology with the use of this powerful model organism. The first chapter is an introduction to the anatomy of the C. elegans nervous system. This chapter provides a useful introduction to this system and will help the reader who is less familiar with this system understand the chapters that follow. The next two chapters on learning, conditioning and memory and neuronal specification and differentiation, summarize the current state of the C. elegans field in these two major areas of neurobiology. The remaining chapters describe studies in C. elegans that have provided particularly exciting insights into neurobiology.
Caenorhabditis Elegans
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Author : Daiana S. Avila
language : en
Publisher:
Release Date : 2019
Caenorhabditis Elegans written by Daiana S. Avila and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Science categories.
Caenorhabditis elegans - An Overview and Emerging Roles in Studying Disease explores different disease models that have been successfully validated in this nematode, either to unravel disease mechanisms or to perform drug screenings. This nonpathogenic organism has helped to firstly identify genetic mechanisms important in cancer (Ras and Bcl oncogene signaling), aging (insulin signaling), and nervous system development (UNC-6/Netrin signaling). Human conditions such as aging/frailty (Chapter One), metabolic syndrome (Chapter Two), neurodegenerative diseases (Chapters Three and Four) and neurodegeneration induced by chemicals (Chapters Three and Five) are recapitulated in C. elegans. The construction of transgenic animals that mimic the diseases, the advances in understanding molecularly these conditions, potential new treatments and limitations of the models are reviewed in these chapters. Notably, the authors that contributed to this book are from different parts of the world due to the widespread use of this nematode in research.