Calcium In Muscle Contraction
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Calcium In Muscle Contraction
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Author : Johann C. Rüegg
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Calcium In Muscle Contraction written by Johann C. Rüegg and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Recent years have witnessed an explosion of knowledge lea- ding to a molecular understanding of the mechanisms of ac- tion of calcium on excitation and contraction coupling and its role in the regulation of contractility. This book highlights the most recent progress as well as providing a historial perspective of the field. It presents a concise and comprehensive overview of our current knowledge regar- ding calcium channels and regulatory proteins as well as in- tracellular calcium handling and the mechanisms underlying the activation of contractile proteins. It also describes how these basic mechanisms have been adapted in various types of muscle, especially in cardiac and smooth muscle.
Calcium In Muscle Activation
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Author : Johann C. Rüegg
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Calcium In Muscle Activation written by Johann C. Rüegg and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
This book offers a comparative and interdisciplinary approach to excitation-contraction-coupling in smooth and striated mus cles, including the myocardium. It is an account of the path ways and mechanisms by which cellular calcium is handled and activates the contractile proteins. It also describes how these mechanisms are adapted in various kinds of muscle to meet specific functional requirements, such as speed or economy. This monograph then presents facts, ideas and theories and the evidence on which they are based, and ifit stimulates others and furthers research, it will have served its purpose. All of the chapters are self-contained and may be read in any order, but readers unfamiliar with muscle are recommended to start with the introductory chapter on excitation and contraction. During all the years of writing this book, I received enormous help from Isolde Berger who corrected, edited and transformed my innumerable notes and drafts into a readable manuscript; she also compiled the list of references and the Subject Index. I owe a great debt of gratitude to her and also to Claudia Zeugner, who prepared the figures with expertise and care. Then I would like to thank the Deutsche F orschungs gemeinschaft and the Fritz-Thyssen-Stiftung for supporting the work of my Department which has been reported in this monograph. A great many people contributed with helpful discussions.
Regulation Of Smooth Muscle Contraction
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Author : Robert S. Moreland
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Regulation Of Smooth Muscle Contraction written by Robert S. Moreland and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Sixth Annual Graduate Hospital Research Symposium REGULATION OF SMOOTH MUSCLE PROGRESS IN SOLVING THE PUZZLE Every so often a scientific conference comes at a time when everyone has new and exciting information, when old "dogmas" do not seem to be as well established, and when speakers and participants alike are ready to challenge interpretations of old and new experimental data. This was such a conference. What turns on a smooth muscle cell? The precise answer to this question has eluded scientists for much longer than I have been involved in the field. We know that an increase in cytosolic calcium is necessary and we know that phosphorylation of the 20 kDa myosin light chain is an important step in the process. We do not know if other processes are necessary for the initiation and lor maintenance of a smooth muscle contraction nor do we know if other processes modulate the regulation of contraction. The goal of the symposium on which this volume is based was to explore the most current hypotheses for the answers to these questions. I believe that after reading the chapters included in this volume, you will agree that this goal was achieved. The importance of calcium and calmodulin dependent myosin light chain phosphoryla tion in the regulation of smooth muscle contraction was reinforced by many presentations. However, the status of myosin light chain phosphorylation as a simple calcium dependent switch came under serious suspicion.
New Concepts In The Control Of Muscle Contraction
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Author : Gerry A. Smith
language : en
Publisher: Rowans Scientific
Release Date : 2007
New Concepts In The Control Of Muscle Contraction written by Gerry A. Smith and has been published by Rowans Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Calcium-binding proteins categories.
This is a collection of papers that presents a novel interpretation of data from the literature to reason logically for an overlooked mechanism of stimulus-contraction coupling in muscle. This mechanism is then used to explain aspects of the puzzles relating to both an important physiological function of the heart, The Frank-Starling Law, and the basis of a common inherited disease state, familial hypertrophic cardiomyopathy (FHCM).
Muscular Contraction
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Author : Robert Malcolm Simmons
language : en
Publisher: Cambridge University Press
Release Date : 1992-06-26
Muscular Contraction written by Robert Malcolm Simmons and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-06-26 with Medical categories.
Composed of a set of chapters contributed by past and present collaborators of the Nobel laureate Sir Andrew Huxley, this book covers the areas of muscle research to which Huxley made major contributions. The purpose of the book is to discuss the way that muscles work, asking questions at a fundamental level about the molecular basis of muscle tone production and muscle contraction. The majority of the chapters are concerned with muscle physiology and the relation between structure and function. The process of activation of muscles is discussed, along with the mechanism of contraction itself. Although most of the book deals with vertebrate skeletal muscle, several chapters cover cardiac muscle. Also featured are two chapters discussing Sir Andrew's achievements in both nerve and muscle physiology.
Calcium Homeostasis In Skeletal Muscle Function Plasticity And Disease
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Author : Matias Mosqueira
language : en
Publisher: Frontiers Media SA
Release Date : 2021-05-28
Calcium Homeostasis In Skeletal Muscle Function Plasticity And Disease written by Matias Mosqueira and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-28 with Science categories.
Calcium In Muscle Activation
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Author : Johann Caspar Rüegg
language : en
Publisher: Springer
Release Date : 1988
Calcium In Muscle Activation written by Johann Caspar Rüegg and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Biochemistry categories.
Excitation Contraction Coupling In Skeletal Cardiac And Smooth Muscle
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Author : George B. Frank
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Excitation Contraction Coupling In Skeletal Cardiac And Smooth Muscle written by George B. Frank and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The Third International Symposium on Excitation-Contraction Coupling in Skeletal, Cardiac, and Smooth Muscle, organized by George Frank, C. Paul Bianchi, and Henk E. DJ. ter Keurs, was held in Banff Centre, Banff, Alberta, Canada during June 26 to June 30, 1991. The theme of these symposia has been to recognize the similarities and dissimilarities of excitation-contraction coupling in skeletal, cardiac, and smooth muscle. Cross fertilization of concepts of excitation-contraction coupling in these three types of muscle has occurred since the early studies in the late fifties and early sixties on skeletal muscle. Investigators in each field meet only at specialized symposia which exclude investigators in the other fields. The purpose of the symposia has been to bring together international investigators studying excitation-contraction coupling in skeletal, cardiac, and smooth muscle so that we may learn from each other and hence provide a more global concept of excitation-contraction. The Third International Symposia has accomplished its objective as we recognize that calcium channels of the sarcolemma and the sarcoplasmic reticulum play key essential roles in excitation-contraction coupling in all three types of muscles. In skeletal muscle the recognition that E-C coupling consists of two parallel mechanisms, one dependent upon a dihydropyridine voltage-sensitive sensors coupled to calcium release from the terminal cisternae via the ryanodine sensitive channel in the foot structure of the triad.
Molecular And Cellular Aspects Of Muscle Contraction
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Author : Haruo Sugi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Molecular And Cellular Aspects Of Muscle Contraction written by Haruo Sugi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This volume presents the proceedings of a muscle symposium, which was supported by the grant from the Fujihara Foundation of Science to be held as the Fourth Fujihara Seminar on October 28 -November 1, 2002, at Hakone, Japan. The Fujihara Seminar covers all fields of natural science, while only one proposal is granted every year. It is therefore a great honor for me to be able to organize this meeting. Before this symposium, I have organized muscle symposia five times, and published the proceedings: " Cross-bridge Mechanism in Muscle Contraction (University of Tokyo Press, 1978), "Contractile Mechanisms in Muscle" (plenum, 1984); "Molecular Mechanisms of Muscle Contraction" (plenum, 1988); "Mechanism of MyofIlament Sliding in Muscle contraction" (plenum, 1993); "Mechanisms of Work Production and Work Absorption in Muscle" (plenum, 1998). As with these proceedings, this volume contains records of discussions made not only after each presentation but also during the periods of General Discussion, in order that general readers may properly evaluate each presentation and the up-to-date situation of this research field. It was my great pleasure to have Dr. Hugh Huxley, a principal discoverer of the sliding fIlament mechanism in muscle contraction, in this meeting. On my request, Dr. Huxley kindly gave a special lecture on his monumental discovery of myofIlament-lattice structure by X-ray diffraction of living skeletal muscle. I hope general readers to learn how a breakthrough in a specific research field can be achieved.
Molecular Control Mechanisms In Striated Muscle Contraction
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Author : R.J. Solaro
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17
Molecular Control Mechanisms In Striated Muscle Contraction written by R.J. Solaro and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Medical categories.
Molecular Control Mechanisms in Striated Muscle Contraction addresses the molecular mechanisms by which contraction of heart and skeletal muscles is regulated, as well as the modulation of these mechanisms by important (patho)physiological variables such as ionic composition of the myoplasm and phosphorylations of contractile and regulatory proteins. For the novice, this volume includes chapters that summarize current understanding of excitation-contraction coupling in striated muscles, as well as the compositions and structures myofibrillar thick and thin filaments. For the expert, this volume presents detailed pictures of current understanding of the mechanisms underlying the CA2+ regulation of contraction in heart and skeletal muscles and discusses important directions for future investigation.