Cancer Informatics
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Cancer Informatics In The Post Genomic Era
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Author : Igor Jurisica
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-04
Cancer Informatics In The Post Genomic Era written by Igor Jurisica and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-04 with Medical categories.
Cancer Informatics in Post-Genomic Era provides both the necessary methodology and practical information tools for analyzing data in the field of medical information science. This, of course, requires analytic tools. Those tools are garnered by developing and assessing methods and systems for the acquisition, processing, and interpretation of patient data, aided by scientific discovery. Key challenges in this field include integrating research and clinical care, sharing data, and establishing partnerships within and across sectors of patient diagnosis and treatment.
Cancer Informatics
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Author : John S. Silva
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Cancer Informatics written by John S. Silva and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Cancer Informatics chronicles the development of the National Cancer Institute's new Cancer Informatics Infrastructure (CII) - an information management system infrastructure designed to faciliate clinical trials, provide for reliable, secure information exchange, and improve patient care. The book details the challenges involved in creating and managing such a knowledge base, including technologies, standards, and current, state-of-the-art applications. The ultimate goal of CII is to function as an enabler of clinical trials, expediting the clinical trials lifecycle, faciliating faster and safer drug development and more appropriate treatment choices for cancer patients. Contributors address the role the CII must play in converting the growing knowledge of genes, proteins, and pathways into appropriate preventative, diagnostic, and therapeutic measures. Presented in four sections, the first provides an overview of the processes involved in moving the infrastructure for cancer from theory into practice. Sections two through four offer the latest work done in the areas of technology, cancer-specific and national standards, and applications to faciliate clinical trials.
Oncology Informatics
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Author : Bradford W. Hesse
language : en
Publisher: Academic Press
Release Date : 2016-03-17
Oncology Informatics written by Bradford W. Hesse and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-17 with Computers categories.
Oncology Informatics: Using Health Information Technology to Improve Processes and Outcomes in Cancer Care encapsulates National Cancer Institute-collected evidence into a format that is optimally useful for hospital planners, physicians, researcher, and informaticians alike as they collectively strive to accelerate progress against cancer using informatics tools. This book is a formational guide for turning clinical systems into engines of discovery as well as a translational guide for moving evidence into practice. It meets recommendations from the National Academies of Science to "reorient the research portfolio" toward providing greater "cognitive support for physicians, patients, and their caregivers" to "improve patient outcomes." Data from systems studies have suggested that oncology and primary care systems are prone to errors of omission, which can lead to fatal consequences downstream. By infusing the best science across disciplines, this book creates new environments of "Smart and Connected Health." Oncology Informatics is also a policy guide in an era of extensive reform in healthcare settings, including new incentives for healthcare providers to demonstrate "meaningful use" of these technologies to improve system safety, engage patients, ensure continuity of care, enable population health, and protect privacy. Oncology Informatics acknowledges this extraordinary turn of events and offers practical guidance for meeting meaningful use requirements in the service of improved cancer care. Anyone who wishes to take full advantage of the health information revolution in oncology to accelerate successes against cancer will find the information in this book valuable. Presents a pragmatic perspective for practitioners and allied health care professionals on how to implement Health I.T. solutions in a way that will minimize disruption while optimizing practice goals Proposes evidence-based guidelines for designers on how to create system interfaces that are easy to use, efficacious, and timesaving Offers insight for researchers into the ways in which informatics tools in oncology can be utilized to shorten the distance between discovery and practice
Informatics Needs And Challenges In Cancer Research
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2012-10-02
Informatics Needs And Challenges In Cancer Research written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-02 with Medical categories.
As information technology becomes an integral part of health care, it is important to collect and analyze data in a way that makes the information understandable and useful. Informatics tools-which help collect, organize, and analyze data-are essential to biomedical and health research and development. The field of cancer research is facing an overwhelming deluge of data, heightening the national urgency to find solutions to support and sustain the cancer informatics ecosystem. There is a particular need to integrate research and clinical data to facilitate personalized medicine approaches to cancer prevention and treatment-for example, tailoring treatment based on an individual patient's genetic makeup as well as that of the tumor-and to allow for more rapid learning from patient experiences. To further examine informatics needs and challenges for 21st century biomedical research, the IOM's National Cancer Policy Forum held a workshop February 27-28, 2012. The workshop was designed to raise awareness of the critical and urgent importance of the challenges, gaps and opportunities in informatics; to frame the issues surrounding the development of an integrated system of cancer informatics for acceleration of research; and to discuss solutions for transformation of the cancer informatics enterprise. Informatics Needs and Challenges in Cancer Research: Workshop Summary summarizes the workshop.
Oncology Informatics
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Author : Bradford W. Hesse
language : en
Publisher: Academic Press
Release Date : 2016-03-01
Oncology Informatics written by Bradford W. Hesse and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-01 with categories.
Oncology Informatics: Using Health Information Technology to Improve Processes and Outcomes in Cancer Care encapsulates NCI-collected evidence into a format that is optimally useful for hospital planners, physicians, researchers, and informaticians alike as they collectively strive to accelerate progress against cancer using informatics tools. Anyone who wishes to take full advantage of the health information revolution in oncology to accelerate successes against cancer will find the information in this book valuable. It is a translational guide for moving evidence into practice, and meets recommendations from the national Academies of Science to reorient the research portfolio toward providing greater cognitive support for physicians, patients, and their caregivers to improve patient outcomes. Data from systems studies have suggested that oncology and primary care systems are prone to errors of omission that can lead to fatal consequences downstream. By infusing the best science across disciplines, this book creates new environments of smart and connected health and acts as a formational guide for turning clinical systems into engines of discovery. Following recommendations from the IOM's Roundtable on Evidence-Based Medicine, the authors encapsulate best practice for creating a Learning Healthcare System in oncology. Presents a pragmatic perspective for practitioners and allied health care professionals on how to implement Health I.T. solutions in a way that will minimize disruption while optimizing practice goals Proposes evidence-based guidelines for designers on how to create system interfaces that are easy to use, efficacious, and timesaving Offers insight for researchers into the ways in which informatics tools in oncology can be utilized to shorten the distance between discovery and practice
Medical Statistics For Cancer Studies
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Author : Trevor F. Cox
language : en
Publisher: CRC Press
Release Date : 2022-06-23
Medical Statistics For Cancer Studies written by Trevor F. Cox and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-23 with Mathematics categories.
Cancer is a dreaded disease. One in two people will be diagnosed with cancer within their lifetime. Medical Statistics for Cancer Studies shows how cancer data can be analysed in a variety of ways, covering cancer clinical trial data, epidemiological data, biological data, and genetic data. It gives some background in cancer biology and genetics, followed by detailed overviews of survival analysis, clinical trials, regression analysis, epidemiology, meta-analysis, biomarkers, and cancer informatics. It includes lots of examples using real data from the author’s many years of experience working in a cancer clinical trials unit. Features: A broad and accessible overview of statistical methods in cancer research Necessary background in cancer biology and genetics Details of statistical methodology with minimal algebra Many examples using real data from cancer clinical trials Appendix giving statistics revision.
Biomedical Informatics For Cancer Research
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Author : Michael F. Ochs
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-04-06
Biomedical Informatics For Cancer Research written by Michael F. Ochs and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-04-06 with Medical categories.
view, showing that multiple molecular pathways must be affected for cancer to develop, but with different specific proteins in each pathway mutated or differentially expressed in a given tumor (The Cancer Genome Atlas Research Network 2008; Parsons et al. 2008). Different studies demonstrated that while widespread mutations exist in cancer, not all mutations drive cancer development (Lin et al. 2007). This suggests a need to target only a deleterious subset of aberrant proteins, since any tre- ment must aim to improve health to justify its potential side effects. Treatment for cancer must become highly individualized, focusing on the specific aberrant driver proteins in an individual. This drives a need for informatics in cancer far beyond the need in other diseases. For instance, routine treatment with statins has become widespread for minimizing heart disease, with most patients responding to standard doses (Wilt et al. 2004). In contrast, standard treatment for cancer must become tailored to the molecular phenotype of an individual tumor, with each patient receiving a different combination of therapeutics aimed at the specific aberrant proteins driving the cancer. Tracking the aberrations that drive cancers, identifying biomarkers unique to each individual for molecular-level di- nosis and treatment response, monitoring adverse events and complex dosing schedules, and providing annotated molecular data for ongoing research to improve treatments comprise a major biomedical informatics need.
Cancer Diagnostics And Therapeutics
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Author : S. K. Basu
language : en
Publisher: Springer Nature
Release Date : 2022-04-15
Cancer Diagnostics And Therapeutics written by S. K. Basu and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-15 with Medical categories.
This book presents multiple facets of cancer biology, including cancer diagnosis, therapeutics to the latest developments in cancer informatics, and applications of artificial intelligence for improving oncologic care. The initial section of the book discusses factors contributing to the development and causes of cancer. The subsequent sections discuss the basic principle of imaging and therapeutic techniques, including MRI, CT, and positron emission tomography (PET) Scan. The book further, explores the implications of cancer chemotherapy on the immune system and emphasizes the effective management of cancer-related pain. Towards the end, it covers recent advancements in cancer treatment, including targeted therapy, immunotherapy, interventional radiotherapy, and stem cell-based therapy. Lastly, it summarizes essential strategic elements of cancer informatics for improving patient outcome.
Statistics And Informatics In Molecular Cancer Research
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Author : Carsten Wiuf
language : en
Publisher: Oxford University Press
Release Date : 2009-06-18
Statistics And Informatics In Molecular Cancer Research written by Carsten Wiuf and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-18 with Mathematics categories.
A collection of chapters from carefully chosen experts covering the theory behind the complex mathematical, statistical, and bioinformatics tools needed to extract, handle, and process data and their application to real data.
Biomedical Informatics For Cancer Research
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Author : Michael F. Ochs
language : en
Publisher: Springer
Release Date : 2011-07-21
Biomedical Informatics For Cancer Research written by Michael F. Ochs and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-21 with Medical categories.
view, showing that multiple molecular pathways must be affected for cancer to develop, but with different specific proteins in each pathway mutated or differentially expressed in a given tumor (The Cancer Genome Atlas Research Network 2008; Parsons et al. 2008). Different studies demonstrated that while widespread mutations exist in cancer, not all mutations drive cancer development (Lin et al. 2007). This suggests a need to target only a deleterious subset of aberrant proteins, since any tre- ment must aim to improve health to justify its potential side effects. Treatment for cancer must become highly individualized, focusing on the specific aberrant driver proteins in an individual. This drives a need for informatics in cancer far beyond the need in other diseases. For instance, routine treatment with statins has become widespread for minimizing heart disease, with most patients responding to standard doses (Wilt et al. 2004). In contrast, standard treatment for cancer must become tailored to the molecular phenotype of an individual tumor, with each patient receiving a different combination of therapeutics aimed at the specific aberrant proteins driving the cancer. Tracking the aberrations that drive cancers, identifying biomarkers unique to each individual for molecular-level di- nosis and treatment response, monitoring adverse events and complex dosing schedules, and providing annotated molecular data for ongoing research to improve treatments comprise a major biomedical informatics need.