Cancer Modelling And Simulation

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Cancer Modelling And Simulation

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Author : Luigi Preziosi
language : en
Publisher: CRC Press
Release Date : 2003-06-18

Cancer Modelling And Simulation written by Luigi Preziosi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-06-18 with Mathematics categories.

Understanding how cancer tumours develop and spread is vital for finding treatments and cures. Cancer Modelling and Simulation demonstrates how mathematical modelling and computer simulation techniques are used to discover and gain insight into the dynamics of tumour development and growth. It highlights the benefits of tumour modelling, such as discovering optimal tumour therapy schedules, identifying the most promising candidates for further clinical investigation, and reducing the number of animal experiments. By examining the analytical, mathematical, and biological aspects of tumour growth and modelling, the book provides a common language and knowledge for professionals in several disciplines.

Bioinformatics And Biomedical Engineering

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Author : Ignacio Rojas
language : en
Publisher: Springer
Release Date : 2018-04-19

Bioinformatics And Biomedical Engineering written by Ignacio Rojas and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-19 with Science categories.

This two-volume set LNBI 10813 and LNBI 10814 constitutes the proceedings of the 6th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2018, held in Granada, Spain, in April 2018.The 88 regular papers presented were carefully reviewed and selected from 273 submissions. The scope of the conference spans the following areas: bioinformatics for healthcare and diseases; bioinformatics tools to integrate omics dataset and address biological question; challenges and advances in measurement and self-parametrization of complex biological systems; computational genomics; computational proteomics; computational systems for modelling biological processes; drug delivery system design aided by mathematical modelling and experiments; generation, management and biological insights from big data; high-throughput bioinformatic tools for medical genomics; next generation sequencing and sequence analysis; interpretable models in biomedicine and bioinformatics; little-big data. Reducing the complexity and facing uncertainty of highly underdetermined phenotype prediction problems; biomedical engineering; biomedical image analysis; biomedical signal analysis; challenges in smart and wearable sensor design for mobile health; and healthcare and diseases.

Biological Control Systems And Disease Modelling

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Author : Babatunde Ogunnaike
language : en
Publisher: Frontiers Media SA
Release Date : 2021-06-04

Biological Control Systems And Disease Modelling written by Babatunde Ogunnaike and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-04 with Science categories.

Journal Of The National Cancer Institute

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Author :
language : en
Publisher:
Release Date : 1990

Journal Of The National Cancer Institute written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with AIDS (Disease) categories.

Research Awards Index

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Author :
language : en
Publisher:
Release Date : 1984

Research Awards Index written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Medicine categories.

Artificial Intelligence Research And Development

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Author : I. Sanz
language : en
Publisher: IOS Press
Release Date : 2023-11-09

Artificial Intelligence Research And Development written by I. Sanz and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-09 with Computers categories.

Artificial intelligence is no longer solely the preserve of computer scientists and researchers; it is now a part of all our lives, and hardly a day goes by without discussion and debate about the implications of its many applications in the mainstream media. This book presents the proceedings of CCIA 2023, the 25th International Conference of the Catalan Association for Artificial Intelligence, held from 25 - 27 October 2023 in Barcelona, Spain. CCIA serves as an annual forum welcoming participants from around the globe. The theme of the 2023 conference was Supportive AI, the main goals of which are to strengthen collaboration between research and industry by sharing the latest advances in artificial intelligence, and opening discussion about how AI can better support the current needs of industry. A total of 54 submissions were received for the conference, of which the 26 full papers, 18 short papers and 6 abstracts included here were selected after peer review. The papers cover a wide range of topics in Artificial Intelligence, including machine learning, deep learning, social media evaluation, consensus-building, data science, recommender systems, and decision support systems, together with crucial applications of AI in fields such as health, education, disaster response, and the ethical impact of AI on society. The book also includes abstracts of the keynotes delivered by Professor Aida Kamišalić and Dr. Lluis Formiga. Providing a useful overview of some of the latest developments in artificial intelligence, the book will be of interest to all those working in the field.

Modeling Tumor Vasculature

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Author : Trachette L. Jackson
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-11-23

Modeling Tumor Vasculature written by Trachette L. Jackson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-23 with Medical categories.

To profoundly understand biology and harness its intricacies for human benefit and the mitigation of human harm requires cross-disciplinary approaches that incorporate sophisticated computational and mathematical modeling techniques. These integrative strategies are essential to achieve rapid and significant progress in issues, in health and disease, which span molecular, cellular and tissue levels. The use of mathematical models to describe various aspects of tumor growth has a very long history, dating back over six decades. Recently, however, experimental and computational advances have improved our in the understanding of how processes act at multiple scales to mediate the development of tumor vasculature and drive the advancement of cancer. This book will showcase the development and utilization of new computational and mathematical approaches to address multiscale challenges associated with tumor vascular development. In Part I: Cell Signaling and Molecular Aspects of Tumor Blood Vessel Formation, it will be come clear that mathematical modeling can help to biochemically and biomechanically phenotype one of the most important cell types involved in cancer progression: vascular endothelial cells. When subverted by the tumor modulated environment, vascular endothelial cells form a new vascular supply capable of nourishing and translocating cancer cells to other tissues. The models in Part I illustrate the importance of quantitative approaches for gaining a deeper understanding of how normal and abnormal aspects of signal integration culminate in the cell proliferation, migration, and survival decisions that result in pathological tumor angiogenesis. The focus of Part II is the angiogenesis cascade and all of its complexities. Successful angiogenesis is mediated by the intricate interplay between biochemical and biomechanical mechanisms, including cell-cell and cell-matrix interactions, cell surface receptor binding, and intracellular signal transduction. A major challenge facing the cancer research community is to integrate known information in a way that improves our understanding of the principal underpinnings driving tumor angiogenesis and that will advance efforts aimed at the development of new therapies for treating cancer. The chapters in Part II will highlight several mathematical and computational approaches for that can potentially address this challenge. While the first two thirds of the book’s chapters demonstrate how important insights can be gained by studying cell signaling and vascular morphology and function, the series of chapters in Part III: Whole Organ Modeling of Tumor Growth and Vasculature, will integrate vasculature development with tumor growth dynamics. These two processes strongly depend on one another in ways that can only be theoretically investigated by biophysical approaches that cut across several levels of biological organization and describe both the tumor and the developing vasculature as they co-evolve. The purpose of this edited volume is not to provide a comprehensive review of all modeling efforts that address tumor vascular modeling; instead, a variety of interesting and innovative mathematical modeling approaches for understanding the development and effects oftumor vasculature are highlighted in order to illustrate some of the emerging trends in the field.

Computational Modelling And Simulation Of Cancer Growth And Migration Within A 3d Heterogeneous Tissue The Effects Of Fibre And Vascular Structure

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Author : Cicely K. Macnamara
language : en
Publisher:
Release Date : 2019

Computational Modelling And Simulation Of Cancer Growth And Migration Within A 3d Heterogeneous Tissue The Effects Of Fibre And Vascular Structure written by Cicely K. Macnamara and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with categories.

The term cancer covers a multitude of bodily diseases, broadly categorised by having cells which do not behave normally. Since cancer cells can arise from any type of cell in the body, cancers can grow in or around any tissue or organ making the disease highly complex. Our research is focused on understanding the specific mechanisms that occur in the tumour microenvironment via mathematical and computational modeling. We present a 3D individual-based model which allows one to simulate the behaviour of, and spatio-temporal interactions between, cells, extracellular matrix fibres and blood vessels. Each agent (a single cell, for example) is fully realised within the model and interactions are primarily governed by mechanical forces between elements. However, as well as the mechanical interactions we also consider chemical interactions, for example, by coupling the code to a finite element solver to model the diffusion of oxygen from blood vessels to cells. The current state of the art of the model allows us to simulate tumour growth around an arbitrary blood-vessel network or along the striations of fibrous tissue.

Remington

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Author : Adeboye Adejare
language : en
Publisher: Academic Press
Release Date : 2020-11-03

Remington written by Adeboye Adejare and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-03 with Science categories.

The PCP's Bicentennial Edition Remington: The Science and Practice of Pharmacy, Twenty Third Edition, offers a trusted, completely updated source of information for education, training, and development of pharmacists. Published for the first time with Elsevier, this edition includes coverage of biologics and biosimilars as uses of those therapeutics have increased substantially since the previous edition. Also discussed are formulations, drug delivery (including prodrugs, salts, polymorphism. With clear, detailed color illustrations, fundamental information on a range of pharmaceutical science areas, and information on new developments in industry, pharmaceutical industry scientists, especially those involved in drug discovery and development will find this edition of Remington an essential reference. Intellectual property professionals will also find this reference helpful to cite in patents and resulting litigations. Additional graduate and postgraduate students in Pharmacy and Pharmaceutical Sciences will refer to this book in courses dealing with medicinal chemistry and pharmaceutics. - Contains a comprehensive source of principles of drug discovery and development topics, especially for scientists that are new in the pharmaceutical industry such as those with trainings/degrees in chemistry and engineering - Provides a detailed source for formulation scientists and compounding pharmacists, from produg to excipient issues - Updates this excellent source with the latest information to verify facts and refresh on basics for professionals in the broadly defined pharmaceutical industry

Systems Medicine

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Author :
language : en
Publisher: Academic Press
Release Date : 2020-08-24

Systems Medicine written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-24 with Science categories.

Technological advances in generated molecular and cell biological data are transforming biomedical research. Sequencing, multi-omics and imaging technologies are likely to have deep impact on the future of medical practice. In parallel to technological developments, methodologies to gather, integrate, visualize and analyze heterogeneous and large-scale data sets are needed to develop new approaches for diagnosis, prognosis and therapy. Systems Medicine: Integrative, Qualitative and Computational Approaches is an innovative, interdisciplinary and integrative approach that extends the concept of systems biology and the unprecedented insights that computational methods and mathematical modeling offer of the interactions and network behavior of complex biological systems, to novel clinically relevant applications for the design of more successful prognostic, diagnostic and therapeutic approaches. This 3 volume work features 132 entries from renowned experts in the fields and covers the tools, methods, algorithms and data analysis workflows used for integrating and analyzing multi-dimensional data routinely generated in clinical settings with the aim of providing medical practitioners with robust clinical decision support systems. Importantly the work delves into the applications of systems medicine in areas such as tumor systems biology, metabolic and cardiovascular diseases as well as immunology and infectious diseases amongst others. This is a fundamental resource for biomedical students and researchers as well as medical practitioners who need to need to adopt advances in computational tools and methods into the clinical practice. Encyclopedic coverage: ‘one-stop’ resource for access to information written by world-leading scholars in the field of Systems Biology and Systems Medicine, with easy cross-referencing of related articles to promote understanding and further research Authoritative: the whole work is authored and edited by recognized experts in the field, with a range of different expertise, ensuring a high quality standard Digitally innovative: Hyperlinked references and further readings, cross-references and diagrams/images will allow readers to easily navigate a wealth of information