Cancer Modelling And Simulation
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Cancer Modelling And Simulation
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Author : Luigi Preziosi
language : en
Publisher: CRC Press
Release Date : 2003-06-18
Cancer Modelling And Simulation written by Luigi Preziosi and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-06-18 with Mathematics categories.
Understanding how cancer tumours develop and spread is vital for finding treatments and cures. Cancer Modelling and Simulation demonstrates how mathematical modelling and computer simulation techniques are used to discover and gain insight into the dynamics of tumour development and growth. It highlights the benefits of tumour modelling, such as discovering optimal tumour therapy schedules, identifying the most promising candidates for further clinical investigation, and reducing the number of animal experiments. By examining the analytical, mathematical, and biological aspects of tumour growth and modelling, the book provides a common language and knowledge for professionals in several disciplines.
Multiscale Cancer Modeling
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Author : Thomas S. Deisboeck
language : en
Publisher: CRC Press
Release Date : 2010-12-08
Multiscale Cancer Modeling written by Thomas S. Deisboeck and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-08 with Mathematics categories.
Cancer is a complex disease process that spans multiple scales in space and time. Driven by cutting-edge mathematical and computational techniques, in silico biology provides powerful tools to investigate the mechanistic relationships of genes, cells, and tissues. It enables the creation of experimentally testable hypotheses, the integration of dat
Selected Topics In Cancer Modeling
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Author : Nicola Bellomo
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-10
Selected Topics In Cancer Modeling written by Nicola Bellomo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-10 with Mathematics categories.
This collection of selected chapters offers a comprehensive overview of state-of-the-art mathematical methods and tools for modeling and analyzing cancer phenomena. Topics covered include stochastic evolutionary models of cancer initiation and progression, tumor cords and their response to anticancer agents, and immune competition in tumor progression and prevention. The complexity of modeling living matter requires the development of new mathematical methods and ideas. This volume, written by first-rate researchers in the field of mathematical biology, is one of the first steps in that direction.
Computational Modelling And Simulation Of Cancer Growth And Migration Within A 3d Heterogeneous Tissue The Effects Of Fibre And Vascular Structure
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Author : Cicely K. Macnamara
language : en
Publisher:
Release Date : 2019
Computational Modelling And Simulation Of Cancer Growth And Migration Within A 3d Heterogeneous Tissue The Effects Of Fibre And Vascular Structure written by Cicely K. Macnamara and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with categories.
The term cancer covers a multitude of bodily diseases, broadly categorised by having cells which do not behave normally. Since cancer cells can arise from any type of cell in the body, cancers can grow in or around any tissue or organ making the disease highly complex. Our research is focused on understanding the specific mechanisms that occur in the tumour microenvironment via mathematical and computational modeling. We present a 3D individual-based model which allows one to simulate the behaviour of, and spatio-temporal interactions between, cells, extracellular matrix fibres and blood vessels. Each agent (a single cell, for example) is fully realised within the model and interactions are primarily governed by mechanical forces between elements. However, as well as the mechanical interactions we also consider chemical interactions, for example, by coupling the code to a finite element solver to model the diffusion of oxygen from blood vessels to cells. The current state of the art of the model allows us to simulate tumour growth around an arbitrary blood-vessel network or along the striations of fibrous tissue.
Multiscale Modeling Of Cancer
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Author : Vittorio Cristini
language : en
Publisher: Cambridge University Press
Release Date : 2010-09-09
Multiscale Modeling Of Cancer written by Vittorio Cristini and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-09 with Technology & Engineering categories.
Mathematical modeling, analysis and simulation are set to play crucial roles in explaining tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial scales. This book, the first to integrate state-of-the-art numerical techniques with experimental data, provides an in-depth assessment of tumor cell modeling at multiple scales. The first part of the text presents a detailed biological background with an examination of single-phase and multi-phase continuum tumor modeling, discrete cell modeling, and hybrid continuum-discrete modeling. In the final two chapters, the authors guide the reader through problem-based illustrations and case studies of brain and breast cancer, to demonstrate the future potential of modeling in cancer research. This book has wide interdisciplinary appeal and is a valuable resource for mathematical biologists, biomedical engineers and clinical cancer research communities wishing to understand this emerging field.
Spread Of Cancer Cells In Tissues
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Author : W. Duchting
language : en
Publisher:
Release Date : 1980
Spread Of Cancer Cells In Tissues written by W. Duchting and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with categories.
Mathematical Modeling And Simulation Of Colorectal Cancer
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Author : Manjeera Saripalli
language : en
Publisher:
Release Date : 2011
Mathematical Modeling And Simulation Of Colorectal Cancer written by Manjeera Saripalli and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with categories.
Understanding the cancer pathology and develop effective treatment strategies play significant roles in improving cancer survival rates. In this Thesis, evaluations of mathematical modeling and simulation were studied and presented. Colorectal system was investigated from gene and cell levels. The Hardware Descriptive Language (HDL) package and codes were developed to simulate the cancer models. Representative codes and figures were illustrated. Results suggest that the HDL is an effective method to conduct the modeling and simulation of cancers. It is essential to develop advanced technology such as HDL modeling and simulation to improve our understandings to fight cancer and save lives.
Mathematical Modeling And Simulation In An Individual Cancer Cell Associated With Invadopodia Formation
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Author : Mohd. Ariff Admon
language : en
Publisher:
Release Date : 2015
Mathematical Modeling And Simulation In An Individual Cancer Cell Associated With Invadopodia Formation written by Mohd. Ariff Admon and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
Multiscale Modeling And Simulation Of Shock Wave Induced Failure In Materials Science
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Author : Martin Oliver Steinhauser
language : en
Publisher: Springer
Release Date : 2018-02-24
Multiscale Modeling And Simulation Of Shock Wave Induced Failure In Materials Science written by Martin Oliver Steinhauser and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-24 with Medical categories.
Martin Oliver Steinhauser deals with several aspects of multiscale materials modeling and simulation in applied materials research and fundamental science. He covers various multiscale modeling approaches for high-performance ceramics, biological bilayer membranes, semi-flexible polymers, and human cancer cells. He demonstrates that the physics of shock waves, i.e., the investigation of material behavior at high strain rates and of material failure, has grown to become an important interdisciplinary field of research on its own. At the same time, progress in computer hardware and software development has boosted new ideas in multiscale modeling and simulation. Hence, bridging the length and time scales in a theoretical-numerical description of materials has become a prime challenge in science and technology.
The Role Of Model Integration In Complex Systems Modelling
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Author : Manish I. Patel
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-09-08
The Role Of Model Integration In Complex Systems Modelling written by Manish I. Patel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-08 with Technology & Engineering categories.
Model integration – the process by which different modelling efforts can be brought together to simulate the target system – is a core technology in the field of Systems Biology. In the work presented here model integration was addressed directly taking cancer systems as an example. An in-depth literature review was carried out to survey the model forms and types currently being utilised. This was used to formalise the main challenges that model integration poses, namely that of paradigm (the formalism on which a model is based), focus (the real-world system the model represents) and scale. A two-tier model integration strategy, including a knowledge-driven approach to address model semantics, was developed to tackle these challenges. In the first step a novel description of models at the level of behaviour, rather than the precise mathematical or computational basis of the model, is developed by distilling a set of abstract classes and properties. These can accurately describe model behaviour and hence describe focus in a way that can be integrated with behavioural descriptions of other models. In the second step this behaviour is decomposed into an agent-based system by translating the models into local interaction rules. The book provides a detailed and highly integrated presentation of the method, encompassing both its novel theoretical and practical aspects, which will enable the reader to practically apply it to their model integration needs in academic research and professional settings. The text is self-supporting. It also includes an in-depth current bibliography to relevant research papers and literature. The review of the current state of the art in tumour modelling provides added value.