Cap Analysis Gene Expression Cage
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Cap Analysis Gene Expression Cage
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Author : Piero Carninci
language : en
Publisher: CRC Press
Release Date : 2019-05-08
Cap Analysis Gene Expression Cage written by Piero Carninci and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-08 with Science categories.
This book is a guide for users of new technologies, as it includes accurately proven protocols, allowing readers to prepare their samples for experiments. Additionally, it is a guide for the bioinformatics tools that are available for the analysis of the obtained tags, including the design of the software, the sources and the Web. Finally, the book provides examples of the application of these technologies to identify promoters, annotate genomes, identify new RNAs and reconstruct models of transcriptional control. Although examples mainly concern mammalians, the discussion expands to other groups of eukaryotes, where these approaches are complementing genome sequencing.
Promoter Associated Rna
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Author : Sara Napoli
language : en
Publisher: Humana
Release Date : 2018-06-09
Promoter Associated Rna written by Sara Napoli and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-09 with Medical categories.
This volume is divided in four sections; covering genome wide approaches, techniques for characterize of paRNA structural features are described, selecting pa-RNA, and paRNA therapeutic potential. Chapters describe how siRNAsdirected against paRNAs can be applied in vivo to modulate transcription of important genes controlled by paRNAs. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Promoter Associated RNA: Methods and Protocols aims to demonstrate paRNAs as new class of regulatory molecules, to further investigate and value as tools for fine transcriptional tuning.
Bioinformatics For Cancer Immunotherapy
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Author : Sebastian Boegel
language : en
Publisher: Humana
Release Date : 2021-03-17
Bioinformatics For Cancer Immunotherapy written by Sebastian Boegel and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-17 with Medical categories.
This volume focuses on a variety of in silico protocols of the latest bioinformatics tools and computational pipelines developed for neo-antigen identification and immune cell analysis from high-throughput sequencing data for cancer immunotherapy. The chapters in this book cover topics that discuss the two emerging concepts in recognition of tumor cells using endogenous T cells: cancer vaccines against neo-antigens presented on HLA class I and II alleles, and checkpoint inhibitors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Bioinformatics for Cancer Immunotherapy: Methods and Protocols is a valuable research tool for any scientist and researcher interested in learning more about this exciting and developing field.
Enhancers And Promoters
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Author : Tilman Borggrefe
language : en
Publisher: Humana
Release Date : 2022-08-27
Enhancers And Promoters written by Tilman Borggrefe and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-27 with Science categories.
This volume contains cutting-edge techniques to study the function of enhancers and promoters in depth. Chapters are divided into six sections and describe enhancer-promoter transcripts, nucleosome occupancy, DNA accessibility, chromatin interactions, protein-DNA interactions, functional analyses, and DNA methylation assays. Written in the Methods in Molecular Biology series format, chapters include comprehensive introductions, lists of the necessary materials and reagents, step-by-step laboratory protocols, and useful suggestions for troubleshooting. Authoritative and cutting-edge, Enhancers and Promoters: Methods and Protocols is a useful guide for future experiments. Chapters 4 and 11 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com
Tag Based Next Generation Sequencing
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Author : Matthias Harbers
language : en
Publisher: John Wiley & Sons
Release Date : 2012-02-13
Tag Based Next Generation Sequencing written by Matthias Harbers and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-13 with Science categories.
Tag-based approaches were originally designed to increase the throughput of capillary sequencing, where concatemers of short sequences were first used in expression profiling. New Next Generation Sequencing methods largely extended the use of tag-based approaches as the tag lengths perfectly match with the short read length of highly parallel sequencing reactions. Tag-based approaches will maintain their important role in life and biomedical science, because longer read lengths are often not required to obtain meaningful data for many applications. Whereas genome re-sequencing and de novo sequencing will benefit from ever more powerful sequencing methods, analytical applications can be performed by tag-based approaches, where the focus shifts from 'sequencing power' to better means of data analysis and visualization for common users. Today Next Generation Sequence data require powerful bioinformatics expertise that has to be converted into easy-to-use data analysis tools. The book's intention is to give an overview on recently developed tag-based approaches along with means of their data analysis together with introductions to Next-Generation Sequencing Methods, protocols and user guides to be an entry for scientists to tag-based approaches for Next Generation Sequencing.
World Congress Of Medical Physics And Biomedical Engineering 2006
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Author : Sun I. Kim
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-07-05
World Congress Of Medical Physics And Biomedical Engineering 2006 written by Sun I. Kim and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-05 with Technology & Engineering categories.
These proceedings of the World Congress 2006, the fourteenth conference in this series, offer a strong scientific program covering a wide range of issues and challenges which are currently present in Medical physics and Biomedical Engineering. About 2,500 peer reviewed contributions are presented in a six volume book, comprising 25 tracks, joint conferences and symposia, and including invited contributions from well known researchers in this field.
Long Noncoding Rnas In Plants
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Author : Santosh Kumar Upadhyay
language : en
Publisher: Academic Press
Release Date : 2020-11-13
Long Noncoding Rnas In Plants written by Santosh Kumar Upadhyay and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-13 with Science categories.
The growth of human population has increased the demand for improved yield and quality of crops and horticultural plants. However, plant productivity continues to be threatened by stresses such as heat, cold, drought, heavy metals, UV radiations, bacterial and fungal pathogens, and insect pests. Long noncoding RNAs are associated with various developmental pathways, regulatory systems, abiotic and biotic stress responses and signaling, and can provide an alternative strategy for stress management in plants. Long Noncoding RNAs in Plants: Roles in development and stress provides the most recent advances in LncRNAs, including identification, characterization, and their potential applications and uses. Introductory chapters include the basic features and brief history of development of lncRNAs studies in plants. The book then provides the knowledge about the lncRNAs in various important agricultural and horticultural crops such as cereals, legumes, fruits, vegetables, and fiber crop cotton, and their roles and applications in abiotic and biotic stress management. Includes the latest advances and research in long noncoding RNAs in plants Provides alternative strategies for abiotic and biotic stress management in horticultural plants and agricultural crops Focuses on the application and uses of long noncoding RNAs
The Handbook Of Plant Functional Genomics
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Author : Guenter Kahl
language : en
Publisher: John Wiley & Sons
Release Date : 2008-07-21
The Handbook Of Plant Functional Genomics written by Guenter Kahl and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-07-21 with Science categories.
In this incisive, concise overview of this booming field, the editors -- two of the leading figures in the field with a proven track record -- combine their expertise to provide an invaluable reference on the topic. Following a treatment of transcriptome analysis, the book goes on to discuss replacement and mutation analysis, gene silencing and computational analysis. The whole is rounded off with a look at emerging technologies. Each chapter is accompanied by a concise overview, helping readers to quickly identify topics of interest, while important, carefully selected words and concepts are explained in a handy glossary. Equally accessible to both experienced scientists and newcomers to the field.
Kidney
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Author : Sang Geon Kim
language : en
Publisher: CRC Press
Release Date : 2013-09-11
Kidney written by Sang Geon Kim and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-11 with Medical categories.
Bridging the gap between advances in basic biology and chemistry and technological applications in the field of toxicity assessments, this book describes major areas of progress in the laboratory and clinic. In the first section, aspects of cellular organelles are discussed. The second section covers the basic principles and applications of modern
Knowledge Based Bioinformatics
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Author : Gil Alterovitz
language : en
Publisher: John Wiley & Sons
Release Date : 2011-04-20
Knowledge Based Bioinformatics written by Gil Alterovitz and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-20 with Medical categories.
There is an increasing need throughout the biomedical sciences for a greater understanding of knowledge-based systems and their application to genomic and proteomic research. This book discusses knowledge-based and statistical approaches, along with applications in bioinformatics and systems biology. The text emphasizes the integration of different methods for analysing and interpreting biomedical data. This, in turn, can lead to breakthrough biomolecular discoveries, with applications in personalized medicine. Key Features: Explores the fundamentals and applications of knowledge-based and statistical approaches in bioinformatics and systems biology. Helps readers to interpret genomic, proteomic, and metabolomic data in understanding complex biological molecules and their interactions. Provides useful guidance on dealing with large datasets in knowledge bases, a common issue in bioinformatics. Written by leading international experts in this field. Students, researchers, and industry professionals with a background in biomedical sciences, mathematics, statistics, or computer science will benefit from this book. It will also be useful for readers worldwide who want to master the application of bioinformatics to real-world situations and understand biological problems that motivate algorithms.