Capillary Electrophoresis Mass Spectrometry
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Capillary Electrophoresis Mass Spectrometry Ce Ms
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Author : Gerhardus de Jong
language : en
Publisher: John Wiley & Sons
Release Date : 2016-09-13
Capillary Electrophoresis Mass Spectrometry Ce Ms written by Gerhardus de Jong and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-13 with Science categories.
This monograph offers the reader a complete overview on both principles and applications of CE-MS. Starting with an introductory chapter on detection in CE, also related and more specialized techniques such as electrophoretic and chromatographic preconcentration are discussed. A special emphasis is put on CE-MS interfaces, which are described in detail. In a separate chapter, attention is paid to sheath-liquid interfacing. The developments and possibilities of microchip CE-MS are also described. Applications to all relevant areas are discussed in distinct chapters, each written by experts in the respective fields. Besides applications in pharmaceutical analysis and bioanalysis, recent implementations in food science, forensic analysis, analysis of intact proteins, metabolomics and proteomics are highlighted. MS is a perfectly appropriate detection system for CE, as efficient separation is coupled to sensitive and selection detection. Moreover, MS can provide structure information on the separated compounds. CE-MS has now been developed into a strong hyphenated system complementary to LC-MS. This monograph is an unique source of knowledge for everyone dealing with and interested in CE-MS.
Capillary Electrophoresis Mass Spectrometry For Proteomics And Metabolomics
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Author : Rawi Ramautar
language : en
Publisher: John Wiley & Sons
Release Date : 2022-10-03
Capillary Electrophoresis Mass Spectrometry For Proteomics And Metabolomics written by Rawi Ramautar and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-03 with Science categories.
Capillary Electrophoresis—Mass Spectrometry for Proteomics and Metabolomics A powerful and essential resource for researchers with an interest in CE-MS In Capillary Electrophoresis—Mass Spectrometry for Proteomics and Metabolomics: Principles and Applications, a team of distinguished researchers delivers a comprehensive overview of bioanalytical capillary electrophoresis coupled to mass spectrometry (CE-MS). The book explains foundational principles, technology as well the strategies and techniques used in data analysis for metabolic and proteomic studies. It also provides a global overview of recent developments and advances for improving CE-MS sensitivity and reproducibility. An essential handbook for everyone performing metabolomic and proteomic analysis, the information provided here will assist researchers in tapping into the full potential of this technique to answer biological and clinical questions. Readers will also find: A thorough introduction to the principles of capillary electrophoresis, including its fundamentals, CE separation modes, capillary coatings, and the fundamentals of mass spectrometry In-depth examinations of technological developments in capillary electrophoresis, including sample preparation, online preconcentration, detection sensitivity, and metabolic coverage Comprehensive discussions of metabolomic studies, including their biomedical and clinical applications Recent advances in proteomics, including top-down and bottom-up approaches Perfect for analytical and clinical chemists, Capillary Electrophoresis—Mass Spectrometry for Proteomics and Metabolomics: Principles and Applications will also earn a place in the libraries of biochemists, molecular biologists, and other molecular life scientists.
Capillary Electrophoresis Mass Spectrometry Ce Ms
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Author : Gloria Ann Bach
language : en
Publisher:
Release Date : 1999
Capillary Electrophoresis Mass Spectrometry Ce Ms written by Gloria Ann Bach and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with categories.
Capillary Electrophoresis Mass Spectrometry
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Author : Christian Neusüß
language : en
Publisher: Springer Nature
Release Date : 2022-08-08
Capillary Electrophoresis Mass Spectrometry written by Christian Neusüß and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-08 with Science categories.
This volume details aspects and applications of interfacing capillary electrophoresis (CE) with mass spectrometry (MS). Chapters guide readers through approaches based on different types of CE-MS interfaces such as (nano)sheath liquid, porous tip, and liquid junction, as well as various capillary coatings, and a broad range of applications including several top-down and bottom-up proteomic approaches. Additionally, a list of analyte targets was provided consisting of amphetamines, antibiotics, carbohydrates (including glycosaminoglycans and glycopeptides), enantiomers, extracellular matrix metabolites, monoclonal antibodies, and nanoparticles, and therefore covers numerous fields of applications such as pharmaceutical, biomedical, food, agrochemical, and environmental analysis. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Capillary Electrophoresis-Mass Spectrometry: Methods and Protocols aims to provide highly valuable information for both beginners and experts in the field be it students, technical staff, and scientists.
Capillary Electrophoresis
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Author : Christian Neusüß
language : en
Publisher: Wiley-VCH
Release Date : 2015-07-07
Capillary Electrophoresis written by Christian Neusüß and has been published by Wiley-VCH this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-07 with Science categories.
This first book to deal with this modern and powerful tool in instrumental analytical chemistry focuses on practical issues, making it a useful guide for both beginners and experienced scientists. The first part describes the methodological background for the coupling of electromigrative separation techniques with mass spectrometry, discussing various separation techniques, interfacing options and MS detection systems. The second part focuses on method development, applications and aspects of quantification and validation. The whole is rounded off with a look at future developments.
Capillary Electrophoresis Mass Spectrometry
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Author : James Q. Xia
language : en
Publisher: Springer
Release Date : 2016-11-08
Capillary Electrophoresis Mass Spectrometry written by James Q. Xia and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-08 with Science categories.
This book covers the latest developments in capillary electrophoresis-mass spectrometry for the analysis of therapeutic proteins. The application of capillary electrophoresis-mass spectrometry (CE-MS) coupling technology in the analysis of recombinant therapeutic proteins is detailed thoroughly. Specific topics include recent developments in coupling capillary electrophoresis with mass spectrometry for the quality control of monoclonal antibody therapeutics, top-down analysis of monoclonal antibody using the CE-MS platform, and detection of host cell protein impurities. Comprehensive characterization of antibody-drug conjugates (ADCs) by coupling capillary electrophoresis with mass spectrometry is also covered. This is an ideal book for scientists in the life science and biopharmaceutical industry who are working on characterizing the PTMs of monoclonal antibodies, as well as graduate students and researchers in the separation science and biological mass spectrometry fields.
Capillary Electrophoresis Mass Spectrometry Ce Ms
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Author : Gerhardus de Jong
language : en
Publisher:
Release Date : 2016
Capillary Electrophoresis Mass Spectrometry Ce Ms written by Gerhardus de Jong and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with SCIENCE categories.
This monograph offers the reader a complete overview on both principles and applications of CE-MS. Starting with an introductory chapter on detection in CE, also related and more specialized techniques such as electrophoretic and chromatographic preconcentration are discussed. A special emphasis is put on CE-MS interfaces, which are described in detail. In a separate chapter, attention is paid to sheath-liquid interfacing. The developments and possibilities of microchip CE-MS are also described. Applications to all relevant areas are discussed in distinct chapters, each written by experts in the respective fields. Besides applications in pharmaceutical analysis and bioanalysis, recent implementations in food science, forensic analysis, analysis of intact proteins, metabolomics and proteomics are highlighted. MS is a perfectly appropriate detection system for CE, as efficient separation is coupled to sensitive and selection detection. Moreover, MS can provide structure information on the separated compounds. CE-MS has now been developed into a strong hyphenated system complementary to LC-MS. This monograph is an unique source of knowledge for everyone dealing with and interested in CE-MS.
Capillary Electrophoresis Mass Spectrometry For Metabolomics
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Author : Rawi Ramautar
language : en
Publisher: Royal Society of Chemistry
Release Date : 2018-07-13
Capillary Electrophoresis Mass Spectrometry For Metabolomics written by Rawi Ramautar and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-13 with Science categories.
Capillary electrophoresis–mass spectrometry (CE-MS) has become a very useful analytical technique for the profiling of highly polar and charged metabolites in biological samples. In this book, the unique features of CE-MS for metabolomics studies are highlighted including CE separation modes, capillary coatings and practical aspects of CE-MS coupling alongside a comprehensive overview of recent technological developments and applications. CE-MS can be considered a relatively new technique in the field of metabolomics and it is therefore important to inform the scientific community about the possibilities of advanced CE-MS approaches for metabolomics studies. This book outlines the potential of this technique for researchers working in metabolomics, bioanalytics and biomarker analysis.
Developing A Capillary Electrophoresis Mass Spectrometry Workflow For Metabolomics
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Author : Nicole M. Schiavone
language : en
Publisher:
Release Date : 2017
Developing A Capillary Electrophoresis Mass Spectrometry Workflow For Metabolomics written by Nicole M. Schiavone and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
Capillary Electrophoresis
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Author : Philippe Schmitt-Kopplin
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-25
Capillary Electrophoresis written by Philippe Schmitt-Kopplin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-25 with Science categories.
This book presents a selection of current capillary electrophoresis methods used to separate representative types of molecules and particles and in combination with different detection techniques. It includes practical details which are hard to find elsewhere. The volume is intended for beginners in the field and provides an overview of the technique and a starting point for the exploration of the defined literature on different application topics.