Carbohydrate Based Vaccines And Immunotherapies
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Carbohydrate Based Vaccines And Immunotherapies
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Author : Zhongwu Guo
language : en
Publisher: John Wiley & Sons
Release Date : 2009-06-09
Carbohydrate Based Vaccines And Immunotherapies written by Zhongwu Guo and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-09 with Science categories.
The fundamental science and the latest developments in carbohydrate-based vaccines The relatively new field of glycoimmunology has emerged from the marriage of glycobiology and immunology, in recognition of the important role carbohydrates play as antigenic determinants. Carbohydrate-Based Vaccines and Immunotherapies comprehensively reviews the state of this exciting field, offering a single source for both the fundamental science and the latest developments. With contributions by leading experts, this resource covers the design, synthesis, evaluation, and applications of various carbohydrate-based vaccines, including polysaccharides, neoglycoproteins, and neoglycolipids. The text approaches vaccine design from a chemical and molecular focus, staying in line with current advances. Key topics covered by Carbohydrate-Based Vaccines and Immunotherapies include: Recent developments towards clinically useful vaccines against bacteria, viruses, parasites, and fungi Using adjuvants to improve immunogenicity and/or immunological properties of vaccines Choosing and designing proper adjuvants for specific targets Abnormal carbohydrates expressed by tumors Carbohydrate-based therapeutic cancer vaccines or cancer immunotherapy Clinical trials results for synthetic cancer vaccines Glycoengineering of cell surface carborhydrates and its anticancer applications Using cell surface carbohydrates for disease diagnosis A single, convenient source of state-of-the-art information from leading authorities in the field, Carbohydrate-Based Vaccines and Immunotherapies is an essential reference for organic chemists and biochemists, academic researchers, and other students and professionals involved in vaccine design.
Carbohydrate Based Therapeutics
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Author : Roberto Adamo
language : en
Publisher: John Wiley & Sons
Release Date : 2023-08-25
Carbohydrate Based Therapeutics written by Roberto Adamo and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-25 with Science categories.
Carbohydrate-Based Therapeutics Comprehensive resource summarizing opportunities and latest progress in design methodologies for carbohydrate-based therapeutics through a disease-oriented approach Carbohydrate-Based Therapeutics covers current progress and explores new frontiers in carbohydrate-based therapeutic applications, utilizing a unique approach by providing a detailed background of diseases coupled with subsequent carbohydrate-based therapies. The link between chemistry and design of novel carbohydrate-based medicines is highlighted and a broad overview of all the potential applications of carbohydrates is given. Emphasis is laid on concepts used for carbohydrate drug design, structure– activity relationship, and impact on health and diseases. The text also discusses newer topics like nanoparticles, material science, and tissue generation. Carbohydrate-Based Therapeutics includes information on: Antimicrobial carbohydrate-based therapies, covering antibacterial and antiviral vaccines, antifungal therapies, anti-influenza therapeutics, and antiadhesive carbohydrates and glycomimetics Anti-cancer carbohydrate-based therapies, covering cancer vaccines and immunotherapy, and carbohydrate tools in cancer biology Carbohydrate-based therapies in metabolic, neuronal, and immune disorders, covering carbohydrate-based therapeutics for lysosomal disorders and neurodegenerative diseases New frontiers in carbohydrate-based therapies, covering carbohydrates for tissue engineering, antiangiogenic and regenerative medicine Providing comprehensive coverage of foundational knowledge on the subject in a unique and highly accessible format while also exploring the state of the art in the field’s applications, Carbohydrate-Based Therapeutics is an essential resource for medicinal, pharmaceutical, and organic chemists, chemists in industry, biochemists, and biotechnologists.
Carbohydrate Based Vaccines
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Author :
language : en
Publisher:
Release Date : 2008
Carbohydrate Based Vaccines written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Carbohydrate drugs categories.
Carbohydrate Based Vaccines
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Author : Bernd Lepenies
language : en
Publisher: Humana
Release Date : 2016-10-15
Carbohydrate Based Vaccines written by Bernd Lepenies and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-15 with Medical categories.
This volume summarizes current cutting-edge methods related to carbohydrate-based vaccines, from the identification of a suitable carbohydrate antigen via the preparation of glycoconjugate vaccines to the characterization of vaccine candidates for their use in pre-clinical and clinical studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Carbohydrate-Based Vaccines: Methods and Protocols aims to be a valuable manual that will facilitate research in the field of carbohydrate-based vaccines.
Towards Better Carbohydrate Vaccines
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Author : R. Bell
language : en
Publisher: John Wiley & Sons
Release Date : 1987-01-01
Towards Better Carbohydrate Vaccines written by R. Bell and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987-01-01 with Carbohydrates categories.
Proceedings of a meeting held by WHO in October l986 at which a number of features of carbohydrates were discussed in relation to the immune system. These features are all related to the development of new potential vaccines and the somewhat timely discussions are reported here to stimulate future progress in this important field.
Carbohydrate Based Vaccines And Immunotherapies
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Author : Zhongwu Guo
language : en
Publisher: John Wiley & Sons
Release Date : 2009-06-17
Carbohydrate Based Vaccines And Immunotherapies written by Zhongwu Guo and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-17 with Science categories.
The fundamental science and the latest developments in carbohydrate-based vaccines The relatively new field of glycoimmunology has emerged from the marriage of glycobiology and immunology, in recognition of the important role carbohydrates play as antigenic determinants. Carbohydrate-Based Vaccines and Immunotherapies comprehensively reviews the state of this exciting field, offering a single source for both the fundamental science and the latest developments. With contributions by leading experts, this resource covers the design, synthesis, evaluation, and applications of various carbohydrate-based vaccines, including polysaccharides, neoglycoproteins, and neoglycolipids. The text approaches vaccine design from a chemical and molecular focus, staying in line with current advances. Key topics covered by Carbohydrate-Based Vaccines and Immunotherapies include: Recent developments towards clinically useful vaccines against bacteria, viruses, parasites, and fungi Using adjuvants to improve immunogenicity and/or immunological properties of vaccines Choosing and designing proper adjuvants for specific targets Abnormal carbohydrates expressed by tumors Carbohydrate-based therapeutic cancer vaccines or cancer immunotherapy Clinical trials results for synthetic cancer vaccines Glycoengineering of cell surface carborhydrates and its anticancer applications Using cell surface carbohydrates for disease diagnosis A single, convenient source of state-of-the-art information from leading authorities in the field, Carbohydrate-Based Vaccines and Immunotherapies is an essential reference for organic chemists and biochemists, academic researchers, and other students and professionals involved in vaccine design.
Carbohydrate Based Vaccines
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Author : A. Krishna Prasad
language : en
Publisher: ACS Symposium
Release Date : 2019-09-23
Carbohydrate Based Vaccines written by A. Krishna Prasad and has been published by ACS Symposium this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-23 with Medical categories.
The past three decades have witnessed the development and regulatory approval of glycoconjugate vaccines against several medically important bacterial pathogens, including Haemophilus influenzae type b, Streptococcus pneumoniae, Neisseria meningitides, and Salmonella typhi. Immunologic protection against these and many other bacterial diseases is mediated through opsonophagocytic antibodies directed against the surface carbohydrates that define the bacterial serogroup or serotype and serve as virulence factors. These vaccines are composed of bacterial capsular polysaccharides chemically conjugated to immunogenic carrier proteins. Given that the diseases caused by these bacterial pathogens are most pronounced in infants and young children, the development of the glycoconjugate vaccine technology has had a considerable impact on public health. Many of the chapters in this volume were assembled as a follow-up from a symposium entitled "Carbohydrate-Based Vaccines and Adjuvants" which took place at the 254th American Chemical Society National Meeting held in Washington, DC (August 2017). The symposium was sponsored by Pfizer and the Carbohydrate (CARB) and Biotechnology (BIOT) divisions. This book, therefore, reflects the importance of this field toward design, development, manufacture and licensure of the complex carbohydrate-based (glycoconjugate) vaccines. The book has been organized into thirteen chapters, which cover a comprehensive landscape including the clinical history, design, development, chemistry, manufacturing and control (CMC) aspects, pre-clinical assays, adjuvants and the various approaches used to develop carbohydrate-based vaccines.
Carbohydrate Based Vaccines
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Author : René Roy
language : en
Publisher: ACS Symposium
Release Date : 2008
Carbohydrate Based Vaccines written by René Roy and has been published by ACS Symposium this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Science categories.
This book is the first of its kind entirely dedicated to carbohydrate vaccines written by renowned scientists with expertise in carbohydrate chemistry and immunochemistry. It covers the synthesis of carbohydrate antigens related to bacteria and parasites such as: Heamophilus influenza, Streptococcus pnemoniae, Shigella flexneri, Candida albicans, Mycobacterium tuberculosis, and Chlamydia. The first three chapters are of wide interest as they cover fundamental concerns in new vaccine developments. The first one presents the immune system and how carbohydrate antigens are processed before protective antibodies are produced. It also illustrates antigen presentation in the context of major histocompatibility complexes (MHCs). The second chapter describes regulatory issues when carbohydrate vaccines are involved while the third one discuss several techniques used in conjugation chemistry and the implication of certain chemical linkages that may induce unexpected anti-linker antibodies. This section will be particularly appealing for those involved in drug-conjugate design, pro-drug developments, and drug vectorization. The book concludes with one chapter that illustrates the principle through which peptide antigens can functionally mimic carbohydrate epitopes, thus, unraveling the potential for peptide surrogates as replacement for complex carbohydrate structures. This book is unique in that it covers all aspects related to carbohydrate vaccines including the success story with the first semi-synthetic bacterial polysaccharide vaccine against Heamophilus influenza type b responsible for pneumonia and meningitis, liable for more than 600,000 infant deaths worldwide in developing countries. The book also presents regulatory issues and will thus be vital for government agencies approving candidate vaccines. It widely covers synthetic methodologies for the attachment of carbohydrate antigens to peptides and immunogenic protein carriers. Vaccines against bacterial antigens, cancer, and parasites are also discussed by worldwide experts in this field in details. No other book contains such a wide panel of different expertise. It will also be useful to students and researchers involved with the immunology of forreings antigens and how the under appreciated carbohydrate antigens are processed by the immune system.
Polysaccharides
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Author : Inamuddin
language : en
Publisher: John Wiley & Sons
Release Date : 2021-05-25
Polysaccharides written by Inamuddin and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-25 with Technology & Engineering categories.
In diesem Werk werden Polysaccharide unter sämtlichen Aspekten betrachtet, von den Grundkonzepten bis zur kommerziellen Vermarktung. Thema der einzelnen Kapitel sind die verschiedenen Arten von Quellen, die Klassifikation, Eigenschaften, Charakterisierung, Verarbeitung, Rheologie und Herstellung von Materialien auf Grundlage von Polysacchariden sowie von Polysaccharid-Gemischen und -Gelen. Anwendung finden Polysaccharide u. a. in der Kosmetik, der Lebensmittelwissenschaft, der Medikamentenverabreichung, der Biomedizin, der Biokraftstoffproduktion, der Schifffahrt, im Verpackungswesen, in der Chromatographie und der Umweltsanierung. Darüber hinaus vermittelt das Werk einen Überblick über die Herstellung von anorganischen und Kohlenstoff-Nanomaterialien aus Polysacchariden. Mit der Betrachtung industrieller Anwendungen schließt das Buch die Lücke zwischen der Forschungsarbeit im Labor und wirtschaftlich nutzbaren Anwendungen in entsprechenden Unternehmen.
General Principles Of Tumor Immunotherapy
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Author : Howard L. Kaufman
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-12
General Principles Of Tumor Immunotherapy written by Howard L. Kaufman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-12 with Medical categories.
This book brings together the world’s leading authorities on tumor immunology. This book describes the basic immunology principles that form the foundation of understanding how the immune system recognizes and rejects tumor cells. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated.