Carbon 13 Nmr Spectroscopy Of Biological Systems
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Carbon 13 Nmr Spectroscopy Of Biological Systems
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Author : Nicolau Beckmann
language : en
Publisher: Elsevier
Release Date : 1995-04-06
Carbon 13 Nmr Spectroscopy Of Biological Systems written by Nicolau Beckmann and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-04-06 with Science categories.
This book is intended to provide an in-depth understanding of 13C NMR as a tool in biological research. 13C NMR has provided unique information concerning complex biological systems, from proteins and nucleic acids to animals and humans. The subjects addressed include multidimensional heteronuclear techniques for structural studies of molecules in the liquid and solid states, the investigation of interactions in model membranes, the elucidation of metabolic pathwaysin vitro and in vivo on animals, and noninvasive metabolic studies performed on humans. The book is a unique mix of NMR methods and biological applications which makes it a convenient reference for those interested in research in this interdisciplinary area of physics, chemistry, biology, and medicine. An interdisciplinary text with emphasis on both 13C NMR methodology and the relevant biological and biomedical issues State-of-the-art 13C NMR techniques are described; Whenever possible, their advantages over other approaches are emphasized The chapters constitute comprehensive reviews and are written by acknowledged experts in their fields Chapters are written in a clear style, and include a large number of illustrations and comprehensive references
Nmr In Living Systems
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Author : T. Axenrod
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Nmr In Living Systems written by T. Axenrod and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In the four decades since its discovery nuclear magnetic resonance (NMR) has become an indispensable tool for obtaining chemical information often. inaccessible by other methods. With the development of instruments of increasingly higher magnetic field strengths, the integration of powerful computers and the availability of an expanding array of flexible software new applications and developments have proliferated rapidly. Among the more exciting new advances is the use of NMR spectroscopy to probe biological systems. The last ten years have witnessed tremendous progress in the development of new NMR imaging and spectroscopic techniques for research and diagnostic applications. The ability to investigate metabolic processes and anatomical structure of intact biological systems under conditions that are totally non-destructive and non-invasive clearly provides much of the impetus for the intense activity that has been generated in the fields of medicine, radiology and the allied basic sciences. Significant advances have been made in this brief period: Whole-body proton NMR imaging today provides anatomical definition of normal and abnormal tissue with a contrast and detection sensitivity often superior to those of X-ray computed tomography and other competing imaging methods. Biochemical pathways, using NMR spectroscopy of protons, carbon-13 and phosphorus-31 nuclei in live animals and man can readily be followed by surface-coil methods to detect metabolites in localized regions. Indicative of the importance and widespread acceptance of these techniques is the explosive growth that the NMR literature is experiencing. This augers well for the future.
Biological Magnetic Resonance
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Author : Lawrence J. Berliner
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Biological Magnetic Resonance written by Lawrence J. Berliner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
We are pleased to present this second volume of a series that has already received much interest. The application of magnetic resonance methods to the study of actual biological systems as contrasted to cell-free samples, although not entirely novel, as demonstrated by Civan and Shporer in Volume I, has taken on new dimensions with the use of phosphorus-31 and carbon-13 NMR in studying cells, tissues, and organelles. The applications of 31 P NMR to such systems is reviewed in this volume, while carbon-13 will be covered in a later one. The use of nitroxide spin labels has grown to the point where it now may be considered a common biological technique. The synthesis and applications of a new class of nitroxides is described in this volume. ESR spectroscopy of paramagnetic ions is a powerful approach to studying molecular and structural details, as the chapter by Boas, Pilbrow, and Smith on the ESR of copper in Volume 1 has shown. In this volume the ESR of molybdenum and iron is treated in a comparable fashion. In the first volume some aspects of 1 H NMR spectroscopy of certain classes of In this volume the high-resolu biological macromolecules were discussed.· tion multinuclear NMR spectra of peptides, including the physiologically significant peptide hormones, are reviewed.
Carbon 13 Nmr Spectroscopy
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Author : Hans-Otto Kalinowski
language : en
Publisher: John Wiley & Sons
Release Date : 1988
Carbon 13 Nmr Spectroscopy written by Hans-Otto Kalinowski and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Science categories.
13C NMR spectroscopy has not only become an established and well documented technique, but is about to yield even more detailed information on increasingly complex organic and biological systems, through the possibilities opened by pulse techniques. This work describes these techniques.
Nmr In Biological Systems
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Author : K.V.R. Chary
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-04-08
Nmr In Biological Systems written by K.V.R. Chary and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-08 with Science categories.
During teaching NMR to students and researchers, we felt the need for a text-book which can cover modern trends in the application of NMR to biological systems. This book covers the entire area of NMR in Biological Sciences (Biomolecules, cells and tissues, animals, plants and drug design). As well as being useful to researchers, this is an excellent book for teaching a course on NMR in Biological Systems.
Nuclear Magnetic Resonance In Biochemistry
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Author : Thomas James
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Nuclear Magnetic Resonance In Biochemistry written by Thomas James and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Nuclear Magnetic Resonance in Biochemistry: Principles and Applications focuses on the principles and applications of nuclear magnetic resonance (NMR) in biochemistry. Topics covered include experimental methods in NMR; the mechanisms of NMR relaxation; chemical and paramagnetic shifts; spin-spin splitting; the use of NMR in investigations of biopolymers and biomolecular interactions; and molecular dynamics in biological and biochemical systems. This text is comprised of eight chapters; the first of which gives an overview of NMR spectroscopy and its use in studies of biological systems. The next two chapters discuss the theoretical basis for NMR applications in biochemistry, with emphasis on Bloch equations, quantum mechanics, correlation function and correlation time, double resonance, and chemical exchange. The reader is then introduced to the basis for chemical shifts and spin-spin splitting, along with several examples of the use of these NMR parameters in studies of small molecule interactions and structure. The experimental apparatus and procedures employed in NMR studies, Fourier transform NMR, and NMR spectral parameters of small molecules interacting with macromolecules are also considered. The book highlights the information obtainable from the spectra of biopolymers, and then concludes with a chapter on NMR investigations of the state of motion of lipids in membranes and model membranes; water in macromolecular and cellular systems; and sodium ion in biological tissue. This book is intended primarily for chemists, biochemists, biophysicists, and molecular biologists, as well as graduate students.
Biological Magnetic Resonance
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Author : Lawrence J. Berliner
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-11
Biological Magnetic Resonance written by Lawrence J. Berliner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-11 with Medical categories.
This volume constitutes a compilation of the latest experiments and theories on a rapidly evolving and maturing field in MRI/MRS, which is the use of the stable isotope 13-C. The 13-C is used to probe the chemistry, mechanism, and function in living systems. All the chapters are written by experts in the field who discuss topics such as `Tracer Theory and the Suitability of 13-C NMR', `Applications of 13-C to Studies of Human Brain Metabolism', etc.
Biological Magnetic Resonance
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Author : Lawrence Berliner
language : en
Publisher: Springer Science & Business Media
Release Date : 1999-01-31
Biological Magnetic Resonance written by Lawrence Berliner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-01-31 with Medical categories.
This volume constitutes a compilation of the latest experiments and theories on a rapidly evolving and maturing field in MRI/MRS, which is the use of the stable isotope 13-C. The 13-C is used to probe the chemistry, mechanism, and function in living systems. All the chapters are written by experts in the field who discuss topics such as `Tracer Theory and the Suitability of 13-C NMR', `Applications of 13-C to Studies of Human Brain Metabolism', etc.
Carbon 13 Nmr Spectroscopy
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Author : Eberhard Breitmaier
language : en
Publisher: Wiley-VCH
Release Date : 1987
Carbon 13 Nmr Spectroscopy written by Eberhard Breitmaier and has been published by Wiley-VCH this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Science categories.
Biological Magnetic Resonance
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Author : Lawrence Berliner
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Biological Magnetic Resonance written by Lawrence Berliner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Judging from the articles published in Biochemistry, magnetic resonance techniques (NMR and ESR) are now among the most popular methods in biochemical research. The series Biological Magnetic Resonance, the fifth volume of which we are proudly presenting, is intended to provide authori tative coverage of topics of current interest. Previous volumes have covered a number of aspects in a thorough and pedagogical fashion rarely found in other publications in this field. Continuing to fulfill the mission of the series, this volume presents a chapter by Baxter, Mackenzie, and Scott on the applications of carbon-13 NMR spectroscopy in investigations of methabolic pathways in vivo. Blom berg and Ruterjans give a comprehensive summary of the use of nitrogen-15 NMR in studies of systems of biological interest. Phosphorus-3I NMR investigations of enzyme systems are described by Rao. Tsai and Bruzik outline the principles of and summarize the state-of-the-art advances in the 18 use of oxygen isotopes e 70 and 0) in phosphorus-3I and oxygen-17 NMR studies of biophosphates. Lipid-protein interactions as reflected in ESR and NMR data are discussed by Devaux. We wish to thank the authors for their cooperation in maintaining the and continued high standards of the series.