Cardiac Allograft Rejection

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Cardiac Allograft Rejection

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Author : G. William Dec
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Cardiac Allograft Rejection written by G. William Dec and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

Heart transplantation remains one of the major scientific achievements of twentieth century medicine. During the past four decades, it has evolved from an unproven experimental surgical technique to the most effective form of therapy for refractory end-stage heart disease. It has captured the public's imagination and expanded our understanding of fundamental immunologic mechanisms that are responsible for cellular and humorally-mediated immunity. Despite its successes, many clinical and scientific problems remain. One or more bouts of acute cellular or humoral (vascular) rejection will occur in over 75% of transplant recipients despite current immunosuppressive strategies. Further, rejection directly results in approximately 20% of post-transplant deaths and is believed to play a major role in the development of late allograft dysfunction and coronary vasculopathy. This book by international experts in the fields of transplantation medicine, immunobiology and cardiac imaging provides the reader with an up-to-date, consise summary of the latest developments in the diagnosis and treatment of acute cardiac rejection. It is axiomatic that a more complete understanding of the pathogenic processes involved in rejection will ultimately lead to its prevention. This volume will be useful to transplant cardiologists, cardiovascular surgeons, cardiac pathologists and transplant scientists who seek to prolong the lifespan and improve the quality of life of their transplant recipients.

Cardiac Transplantation

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Author : Jeffrey D. Hosenpud
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Cardiac Transplantation written by Jeffrey D. Hosenpud and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

Over the past ten years, cardiac transplantation has evolved from an exper imental procedure performed in a handful of university centers to a viable therapeutic modality now performed in more than 150 centers worldwide. The complexity of the procedure, the changing immunosuppressive re gimes, and the follow-up care have necessitated a multidisciplinary ap proach involving a variety of medical, nursing, and social sciences special ties and subspecialties. In addition, health care trainees and referring physicians are increasingly becoming involved in the care of the cardiac transplant recipient. This book does not attempt to be a comprehensive treatise on cardiac transplantation; rather, we hope that it will serve as a manual and guideline for all health professionals involved in cardiac trans plantation. JEFFREY D. HOSENPUD, M.D. Contents Preface v Contributors IX 1. Cardiac Transplantation: An Overview JEFFREY D. HOSENPUD AND ALBERT STARR Immunogenetics and Immunologic Mechanisms of 2. Rejection 15 DOUGLAS J. NORMAN 3. Medical Therapy Tailored for Advanced Heart Failure 33 LYNNE WARNER STEVENSON 4. Ventricular Assistance as a Bridge to Cardiac Transplantation 53 D. GLENN PENNINGTON AND MARC T. SWARTZ Recipient Selection for Cardiac Transplantation 71 5. GEORGE A. PANTELY 6. Donor Selection and Management for Cardiac Transplantation 85 JEFFREY SWANSON AND ADNAN COBANOGLU 7. Operative Techniques and Early Postoperative Care in Cardiac Transplantation 95 ADNAN COBANOGLU Endomyocardial Biopsy: Techniques and Interpretation of 8.

The Pathology Of Cardiac Transplantation

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Author : Ornella Leone
language : en
Publisher: Springer
Release Date : 2017-01-20

The Pathology Of Cardiac Transplantation written by Ornella Leone and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-20 with Medical categories.

This is the first book to focus entirely on the role of pathology in cardiac transplantation, linked to the clinical perspective through clinical–pathological correlation, multidisciplinary team working, and collaborative research. It provides a scientific framework with up-to-date pathological protocols and classification schemes and guides the reader through the chronological phases of the transplant process in a step-by-step approach. Topics include end-stage heart failure with pathologies encountered in the native heart, current issues surrounding donor selection, the multiple faces of rejection pathology correlated with clinical management and immunology, other post-transplant complications, details of pediatric and combined heart/other organ transplantation, and a useful practical appendix. Many high-quality images and illustrative cases are presented, along with learning points and ample references. Transplantation medicine today is continuously changing as collaborative research into novel diagnostic techniques and immunosuppressive therapies translates into improved recipient management and survival. This book is aimed at practicing transplant pathologists and specialist trainees. It will also appeal to general pathologists and to physicians and surgeons involved in cardiac transplantation who need to understand the role of pathology in the clinical management of transplant recipients.

Contemporary Heart Transplantation

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Author : Linda Bogar
language : en
Publisher: Springer
Release Date : 2020-09-10

Contemporary Heart Transplantation written by Linda Bogar and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-10 with Medical categories.

This work provides a one-of- a-kind volume that includes all aspects of heart transplantation from its historic beginning to its current day standards which now make the procedure a long-term treatment option for heart failure patients. The subjects covered include technical aspects of the procurement and implant procedures, as well as the medical nuances of pre-operative preparation and post-transplant immunosuppression management; the current day multi-disciplinary make up of the transplant team along with information on the keys to building and running a successful transplant program; regulatory standards and listing policies and the impact of the growing mechanical circulatory support technologies on the transplant field; and emerging technologies and future possibilities. All chapters are written by experts in the field and include the most up-to-date peer reviewed studies and clinical guidelines. This book gives an ever-changing reference that will become the text of choice for those beginning or continuing their transplant careers.

Clinical Guide To Heart Transplantation

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Author : Jon Kobashigawa
language : en
Publisher: Springer
Release Date : 2017-03-29

Clinical Guide To Heart Transplantation written by Jon Kobashigawa and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-29 with Medical categories.

This is a concise review of up-to-date concepts and techniques in the discipline of heart transplantation. It is a review and reference for practitioners managing patients with advanced heart disease, including patients with end-stage heart failure, mechanical circulatory support or transplant recipients. Heart failure is a major public health issue, with a prevalence of over 5.8 million in the USA, and over 23 million worldwide, and rising. The lifetime risk of developing heart failure is one in five. Heart failure carries substantial morbidity and mortality, with 5-year mortality that rival those of many cancers. As heart transplantation remains the best treatment option for patients with end stage heart failure, this primer will provide valuable information and management strategies for physicians caring for these patients. Also, due to continued shortage in donor organs, heart transplantation is a limited resource – which further underscores the importance of appropriately evaluating patients for transplant candidacy and managing their pre, peri- and post-transplant care for maximum benefit and best outcomes.​

Cardiac Transplantation

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Author : Niloo M. Edwards
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-02-26

Cardiac Transplantation written by Niloo M. Edwards and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-02-26 with Medical categories.

Leading physicians summarize in this easy-to-use and eminently practical handbook the day-to-day management of transplant donors and recipients at Columbia-Presbyterian Medical Center. Topics covered range from surgical techniques, pathology, and immunosuppression, to posttransplant management, pediatric heart transplantation, surgical alternatives, and mechanical circulatory assistance as a bridge to transplantation. The authors also discuss congenital transplant techniques, state-of-the-art perioperative management techniques and protocols, and UNOS regulation and nurse coordination.

The Transplantation And Replacement Of Thoracic Organs

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Author : D.K. Cooper
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-08-20

The Transplantation And Replacement Of Thoracic Organs written by D.K. Cooper and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-20 with Medical categories.

It is a great pleasure for me to contribute a few words as an achieved by many heart transplant centers and the ever improving results of lung transplantation and the functioning of mechanical introduction to the second edition of this volume, first published in 1990 when it was edited by David Cooper and Dimitri cardiac assist devices. Novitzky. The first edition was, in fact, a greatly expanded The current editors bring a wealth of expertise and experience version of an even earlier volume Heart Transplantation, edited to their task, and have blended together absolutely superb con by David Cooper and Robert Lanza and published in 1984. This tributions by many of the world's experts in their fields. This first work, authored by members of the medical staff of Groote comprehensive and highly readable volume documents the Schuur Hospital and the University of Cape Town Medical present 'state of the art' in the field of transplantation and School, was, I believe, the first volume reviewing this relatively replacement of thoracic organs. It provides an invaluable and un new field of medicine. paralleled source of information for those concerned with heart and lung medicine or surgery, and is essential reading for all who The present volume, therefore, continues the documentation of wish to keep abreast of developments in this field.

Handbook Of Cardiac Transplantation

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Author : Robert W. Emery
language : en
Publisher:
Release Date : 1996

Handbook Of Cardiac Transplantation written by Robert W. Emery and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.

Heart And Heart Lung Transplantation

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Author : William A. Baumgartner
language : en
Publisher: W.B. Saunders Company
Release Date : 1990

Heart And Heart Lung Transplantation written by William A. Baumgartner and has been published by W.B. Saunders Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Medical categories.

Heart Transplantation

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Author : D.K. Cooper
language : en
Publisher: Springer
Release Date : 1984

Heart Transplantation written by D.K. Cooper and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Medical categories.

It is a great pleasure for me to contribute a brief introduction to this volume, to which so many of my colleagues at Groote Schuur Hospital and the University of Cape Town Medical School have contributed. Though considerable advances have been made in preventing or treating the complications of heart transplantation, even today a transplant pro gramme remains a major undertaking for a hospital team. The acquisition of a sufficient number of donor hearts, the maintenance of viability of those hearts, and the prevention, diagnosis and treatment of acute and chronic rejection and infection remain major challenges to those caring for patients undergoing this operation. A transplant programme draws into it medical, surgical, nursing and paramedical staff from all quarters of the hospital and medical school, and requires sustained interest and dedication if patients are to be brought successfully through the procedure. If relevant experimental research is also to be carried out at such a centre, which in my opinion is essential, then an even greater number of highly skilled and creative people is required. A few of the authors of this book have been involved with the Groote Schuur heart transplant programme since its inception in December 1967 with the operation on Louis Washkansky. I am sure that none of them (nor I) had any idea of the public interest this operation would attract.