Cardiac Arrhythmias New Therapeutic Drugs And Devices
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Cardiac Arrhythmias New Therapeutic Drugs And Devices
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Author : J. Morganroth
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Cardiac Arrhythmias New Therapeutic Drugs And Devices written by J. Morganroth and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In summary, there are many animal models that are useful in selecting new antiarrhythmic drugs. The selection of which model is most idea depends upon precisely what question is being asked. The large number of experimental models used to evaluate antiarrhythmic compounds points out the inability of anyone model to define the probability of antiarrhythmic efficacy in man. It has therefore become standard practice to utilize a batter of animal models for the evaluation of new antiarrhythmic agents. Each model has its own advantages and disadvantages and it is necessary to understand each model fully in oder to evaluate experimental findings and apply them to clinical settings. We believe that the availability of the chronic myocardial infarction ventricular tachyarrhythmia model provides 1) an excellent opportunity to more precisely understand arrhythmia mechanisms, 2) to develop new techniques such as signal averaging for evaluating late low level potentials identifying hearts at high risk of sudden death 3) to identify new antifibrillatory drugs versus drugs that are effective primarily against PVC's and ventricular tachycardia 4) to identify new surgical techniques to eliminate VT/VF, and 5) to evaluate new pacing modalities including implantable cardioverters. Although all animal models are wrong, many are very useful in furthering our knowledge directed at decreasing the distressingly high mortality from heart disease. NORMAL HtART TACHYCMDIA HtART , .. '" \ I I I I I I I I I .
Cardiac Arrhythmias And Device Therapy Results And Prospectives For The New Century
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Author : I. Eli Ovsyshcher, MD, PhD, FESC, FACC
language : en
Publisher: Wiley-Blackwell
Release Date : 2000-06-15
Cardiac Arrhythmias And Device Therapy Results And Prospectives For The New Century written by I. Eli Ovsyshcher, MD, PhD, FESC, FACC and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-06-15 with Medical categories.
The final decades of this century have been a period of expansive growth for the electrophysiological management of cardiac arrhythmias. Subsequently, the rapid and widespread clinical application of so many technological advances has made the exchange of ideas in this field an urgent necessity. Cardiac Arrhythmias and Device Therapy: Results and Perspectives for the New Century addresses the issue by gathering current, relevant information in a clear, user-friendly format. This book covers a broad spectrum of subjects, including basic electrophysiology (impulse propagation, subthreshold stimulation, genetics and the molecular base of arrhythmias), invasive and noninvasive clinical electrophysiology, and the clinical aspects of cardiac pacing and defibrillation. It provides a comprehensive review of various methods of treatment of atrial fibrillation, and of the role of pacing in prevention of atrial fibrillation and in treatment of congestive heart failure, dilated, hypertrophic, and restrictive cardiomyopathies. The results of recent clinical trials in cardiac pacing and in the prevention and treatment of malignant venticular arrhythmias are also presented. Special sections have been dedicated to the various aspects of preventing sudden death, including the use of internal and external defibrillation. Finally, the book offers a current review of "hot" topics, with personal experiences and critical evaluations by the world-renowned authors. This book will be of interest to all cardiologists, EP technicians, and health care personnel involved in the diagnosis and management of arrhythmias, who wish to gain a complete perspective on modern pacing and electrophysiology.
Cardiac Arrhythmias Interpretation Diagnosis And Treatment Second Edition
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Author : George J. Klein
language : en
Publisher: McGraw-Hill Education / Medical
Release Date : 2019-09-22
Cardiac Arrhythmias Interpretation Diagnosis And Treatment Second Edition written by George J. Klein and has been published by McGraw-Hill Education / Medical this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-22 with Medical categories.
The acclaimed primer of electrophysiology – from two leading experts Cardiac Arrhythmias: Interpretation, Diagnosis and Treatment, Second Edition is a practical clinical guide for healthcare professionals who seek a basic knowledge of electrophysiology and how to interpret and treat patients with arrhythmias. One of the main benefits of this book is the author’s ability to take electrophysiology and break it down clearly and simply so internists and family practitioners who do not have an extensive background in this complex aspect of cardiology can understand it and its relationship to treating arrhythmias. The Second Edition has been updated to include the latest treatment advances, new and important clinical trials, additional cases, and coverage of new drugs and devices; and is enhanced by full-color tracings, and an increased number of tables and illustrations.
Emerging Technologies For Heart Diseases
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Author : Udi Nussinovitch
language : en
Publisher: Academic Press
Release Date : 2020-08-19
Emerging Technologies For Heart Diseases written by Udi Nussinovitch and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-19 with Medical categories.
The increasing pace of advances in cardiology throughout the last few decades has fundamentally altered the natural course of heart patients. In the last few years, available therapies have been revolutionized completely by new transcatheter therapeutic approaches, novel ventricular assist devices, and new drugs. Also, molecular biology and genetics have a rapidly growing impact on cardiovascular diseases, enabling the field of regenerative medicine to become increasingly closer to routine clinical implementation. Emerging Technologies for Heart Diseases was conceived to cover the recent extensive literature on current and novel therapeutic options for cardiac patients. The first volume is dedicated to heart failure and valvular disorders, and the second covers myocardial ischemia and arrhythmias. The clinical topic is addressed in several chapters divided according to the therapeutic approach (mechanical or electrical device-based, or cell and gene-based). Each of the 46 chapters focuses on clinically available solutions, new therapies currently under evaluation in clinical trials, promising preclinical technologies, and emerging concepts and innovations that have not yet been tested in a preclinical model. Also, the book discusses future challenges and opportunities for clinical implementation. Lessons learned from abandoned experimental practices are also covered, giving the readers the widest possible perspective of current therapeutic dilemmas. Overall, this textbook was designed for physicians who want to stay up-to-date with current therapies and those of the future, for biomedical companies, and for those who wish to broaden their knowledge of new cardiovascular therapeutic options. Provides a comprehensive review of the latest therapeutic developments for heart failure, valvular disorders, myocardial ischemia and arrhythmias, and their clinical implications Written by both specialists in the field and established researchers, it delivers a review of emerging medical technologies and presents insight into their therapeutic promise Chapters are arranged according to disease pathogeneses and relevance and include coverage of the mechanical, electrophysiological, and biological approaches for the management of patients with myocardial ischemia and arrhythmias
Fundamental Approaches To The Management Of Cardiac Arrhythmias
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Author : Ruey J. Sung
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Fundamental Approaches To The Management Of Cardiac Arrhythmias written by Ruey J. Sung and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
This new edition provides up-to-date comprehensive coverage of the rapidly evolving field of clinical cardiac electrophysiology. It is designed for physicians, cardiologists, cardiac electrophysiologists, and allied professionals practising or learning the speciality of clinical cardiac electrophysiology. This textbook - written entirely by two practising authorities in the field - offers a cohesive and comprehensive summary of the principles and practice of clinical cardiac electrophysiology. The authors emphasize the clinical approach to the patient and provide a fundamental, yet thorough, discussion of the primary therapeutic modalities used today in a state-of-the-art electrophysiology laboratory, including the latest pharmacotherapy options, catheter ablation treatment, and the newest implantable devices. The authors provide the reader with a concise, organized discussion of the management of patients with benign to life-threatening arrhythmias using the newest concepts, equipment, and techniques of diagnostic and therapeutic electrophysiology.
Bennett S Cardiac Arrhythmias
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Author : David H. Bennett
language : en
Publisher: John Wiley & Sons
Release Date : 2012-10-22
Bennett S Cardiac Arrhythmias written by David H. Bennett and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-22 with Medical categories.
Reviews of previous editions: "...a well conceived practical guide to the interpretation andtreatment of the main cardiac rhythm disturbances." —Lancet "This book presents a concise and simplified approach to thediagnosis and management of abnormalities in cardiac rhythm.... Oneof the book's strengths is the number and quality ofelectrocardiographic tracings" —New England Journal of Medicine "...this book provides an excellent foundation for all thoseinvolved in the care of arrhythmia patients" —British Journal of Hospital Medicine "…would recommend it unreservedly to anaesthetists whowish to improve their knowledge of cardiac arrhythmias" —British Journal of Anaesthesia "This book about cardiac arrhythmias is of much educationalvalue" —European Heart Journal A trusted source for junior doctors, students, nurses andcardiac technicians for over 30 years, the new edition of thisclassic reference continues the winning formula of previouseditions while at the same time incorporating essential new contenton today's most important clinical topics, including: Atrial fibrillation: ablation, drugs, rate control versusrhythm control, risk of systemic embolism, prognosis Indications for and management of implantable defibrillatorsincluding complications such as arrhythmia storms Indications for pacemaker implantation Anticoagulant therapy (for atrial fibrillation) Long QT syndromes and other channelopathies Recently-approved anti-arrhythmia drugs The 8th edition also features the latest guidelines on ECGscreening of athletes and clear guidance for anaesthetists andsurgeons dealing with patients with arrhythmias an/or implantabledevices. Rich with example ECGs and designed for ease of access toinformation, Bennett's Cardiac Arrhythmias is the referenceyou can trust to help you master arrhythmia diagnosis and provideoptimal treatment of any patient under your care.
Arrhythmia Treatment And Therapy
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Author : Raymond Woosley
language : en
Publisher: CRC Press
Release Date : 2000-02-25
Arrhythmia Treatment And Therapy written by Raymond Woosley and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-02-25 with Medical categories.
This vitally important reference traces the progress of antiarrhythmic drug trials and treatment methods-from the vantage point of the clinicians who designed and conducted the studies to objective views of the strengths and weaknesses of the results, identifying unresolved questions or newly created issues. Reviews significant studies in chronological order-providing a clear, informative account of how current thinking about arrhythmia treatment has evolved. Written by over 35 leading experts in the field, Clinical Trials on the Treatment of Arrhythmias emphasizes the need for science-based therapeutics and rigorously controlled clinical trials of drugs and implantable devices compares electrocardiographic monitoring with electrophysiological techniques for arrhythmia management analyzes the landmark Cardiac Arrhythmia Suppression Trial (CAST) evaluates the effectiveness of amiodarone describes sodium and potassium channel blockers and the development of drugs that slow conduction velocity and prolong repolarization and refractoriness investigates the effects of the d-isomer of sotalol on mortality critiques studies on the established efficacy of implantable devices versus amiodarone to benefit post-bypass surgery patients and more! Containing over 600 literature citations, Clinical Trials on the Treatment of Arrhythmias is an invaluable resource for cardiologists and cardiovascular specialists, pharmacologists, pharmaceutical researchers, and graduate and medical school students in these disciplines.
Basis And Treatment Of Cardiac Arrhythmias
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Author : Robert E. Kass
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-09-29
Basis And Treatment Of Cardiac Arrhythmias written by Robert E. Kass and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-09-29 with Medical categories.
This book incorporates the most up-to date information related to mechanisms and treatment of cardiac arrhythmia. Many of the topics discussed in this text reflect very recently undertaken research directions including genetics of arrhythmias, cell signalling molecules as potential therapeutic targets and trafficking to the membrane. These new approaches and implementations of anti-arrhythmic therapy derive from many decades of research as outlined in the first chapter by distinguished Professors Michael Rosen (Columbia University) and Michiel Janse (University of Amsterdam). The text covers changes in approaches to therapy over time, arrhythmias in multiple cardiac regions and over many scales, from gene to protein to cell to tissue to organ.
Sudden Cardiac Death And Congestive Heart Failure
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Author : J. Morganroth
language : en
Publisher:
Release Date : 1983-04-01
Sudden Cardiac Death And Congestive Heart Failure written by J. Morganroth and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983-04-01 with categories.
Cardiac Arrhythmias
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Author : Ambrose S. Kibos
language : en
Publisher: Springer
Release Date : 2016-09-27
Cardiac Arrhythmias written by Ambrose S. Kibos and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-27 with Medical categories.
This book covers all the major aspects associated with pathophysiological development of cardiac arrhythmias (covering enhanced or suppressed automaticity, triggered activity, or re-entry), from basic concepts through disease association, limitations of current pharmacotherapy and implant therapies and on-going trials and analysis of new biomarkers based on current knowledge of cellular interaction and signalling. The book describes novel and state-of-the-art methods for differentiating between the major types of arrhythmia, structural abnormalities and current practice guidelines and determination of risk stratification associated with sudden cardiac death. A particular focus is on arrhythmias associated with atrial fibrillation and includes details of associations with cardiac disease, current detection, analysis and imaging and future perspectives.