Cardiac Cell Biology
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Cardiac Cell Biology
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Author : Elissavet Kardami
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Cardiac Cell Biology written by Elissavet Kardami and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
Cardiac cell biology has come of age. Recognition of activated or modified signaling molecules by specific antibodies, new selective inhibitors, and fluorescent fusion tags are but a few of the tools used to dissect signaling pathways and cross-talk mechanisms that may eventually allow rational drug design. Understanding the regulation of cardiac hypertrophy in all its complexity remains a fundamental goal of cardiac research. Since the advancement of adenovirally mediated gene transfer, transfection efficiency is no longer a limiting factor in the study of cardiomyocytes. A limiting factor in considering cell transplantion as a strategy to repair the damaged heart is cell availability at the right time. Cardiac gap junctions, intercellular communication channels that allow electrical and metabolic coupling and play an important role in arrhythmogenesis are now understood to be exquisite sensors of cardiac change. The reports in this volume incLude elegant studies that made use of cutting edge technological advances and many specialized reagents to address these issues.
Cardiac Cell Biology
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Author :
language : en
Publisher:
Release Date : 2003
Cardiac Cell Biology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.
Cardiac Cytoarchitecture
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Author : Elisabeth Ehler
language : en
Publisher: Springer
Release Date : 2015-03-03
Cardiac Cytoarchitecture written by Elisabeth Ehler and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-03 with Science categories.
This book presents a collection of expert reviews on different subcellular compartments of the cardiomyocyte, addressing fundamental questions such as how these compartments are assembled during development, how they are changed in and by disease and which signaling pathways have been implicated in these processes so far. As such, it offers the first overview of the cell biology of heart disease of its kind, addressing the needs of cell biology students specializing in vascular and cardiac biology, as well as those of cardiologists and researchers in the field of cell biology.
Regenerating The Heart
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Author : Ira S. Cohen
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-03-23
Regenerating The Heart written by Ira S. Cohen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-23 with Science categories.
Medical research made huge strides in treating heart disease in the 20th century, from drug-eluding stents to automatic internal defibrillators. Public awareness of the dangers of heart disease has never been more pervasive. Now, though, ten years into a new millennium, scientists are gearing up for the next great challenges in tackling this pervasive condition. Cell therapy is going to be a key weapon in the fight against heart disease. It has the potential to address many cardiovascular conditions. From heart failure to atrioventricular nodal dysfunction, the young but promising field of cell therapy is set to play a significant role in developing the cures that the upcoming decades of hard work will yield. Regenerating the Heart: Stem Cells and the Cardiovascular System organizes the field into a digestible body of knowledge. Its four sections cover mechanical regeneration, electrical regeneration, cardiac tissues and in vivo stem cell therapies. An array of talented researchers share the fruits of their labors, with chapters covering such crucial issues as the cardiogenic potential of varying stem cell types, the ways in which they might be used to tackle arrhythmias, their possible application to biological replacements for cardiac tissues such as valves, and the varying approaches used in the in vivo evaluation of stem cell therapies, including methods of delivering stem cells to the myocardium. This comprehensive survey of an area of research with such exciting potential is an invaluable resource both for veteran stem cell researchers who need to monitor fresh developments, and for newly minted investigators seeking inspirational examples.
Molecular Mechanisms Of Cardiac Hypertrophy And Failure
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Author : Richard A. Walsh
language : en
Publisher: CRC Press
Release Date : 2005-11-29
Molecular Mechanisms Of Cardiac Hypertrophy And Failure written by Richard A. Walsh and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-29 with Medical categories.
This title reviews current knowledge of the mechanisms contributing to heart failure. Editor Richard Walsh and an internationally renowned team of contributors discuss key advances in molecular and cell biology, biochemistry, and pharmacology, focusing on advances that have a direct bearing on current clinical studies. It highlights developments across a broad range of disciplines, with in-depth coverage of each topic providing background and perspective on current literature. By setting new advances in a broader context, this text allows readers to compare different ideas and evaluate their importance in their own areas of research or clinical practice.
An Essential Guide To Cardiac Cell Therapy
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Author : Emerson Perin
language : en
Publisher: CRC Press
Release Date : 2006-09-15
An Essential Guide To Cardiac Cell Therapy written by Emerson Perin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-09-15 with Medical categories.
Sparked by a new understanding that the development of tissues is not restricted to the embryonic phase of development and thus that regeneration of tissues can occur in adults, the emerging field of stem cell therapy has grown exponentially in the last several years. Crucially, the research and findings associated with stem cell research overlap into many other areas, such as basic cell biology, molecular biology and hematology, and the proliferation of clinical studies involving stem cell research is gradually crossing over into the practice of medicine as many patients may become candidates for such novel treatments. As a response to this, Guide to Cardiac Cell Therapy is a comprehensive but understandable resource that makes this exciting field accessible to clinical practitioners. Bridging the gap between basic science and practice, it is a useful introduction to the area as well as a cutting-edge update of the developments in stem cell therapy as applied to cardiovascular disease.
Cellular And Molecular Pathobiology Of Cardiovascular Disease
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Author : Monte Willis
language : en
Publisher: Academic Press
Release Date : 2013-12-23
Cellular And Molecular Pathobiology Of Cardiovascular Disease written by Monte Willis and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-23 with Medical categories.
Cellular and Molecular Pathobiology of Cardiovascular Disease focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine. No other single text-reference combines clinical cardiology and cardiovascular pathology with enough molecular content for graduate students in both biomedical research and clinical departments. The text is complemented and supported by a rich variety of photomicrographs, diagrams of molecular relationships, and tables. It is uniquely useful to a wide audience of graduate students and post-doctoral fellows in areas from pathology to physiology, genetics, pharmacology, and more, as well as medical residents in pathology, laboratory medicine, internal medicine, cardiovascular surgery, and cardiology. Explains how to identify cardiovascular pathologies and compare with normal physiology to aid research Gives concise explanations of key issues and background reading suggestions Covers molecular bases of diseases for better understanding of molecular events that precede or accompany the development of pathology
The Developing Heart
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Author : Marianne J. Legato
language : en
Publisher: Springer Science & Business Media
Release Date : 1985
The Developing Heart written by Marianne J. Legato and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Gardening categories.
Heart disease, despite recent improvements, continues to be the single most im portant cause of death and disability in the United States. It is estimated that the direct cost of medical care for cardiovascular disease is $6 billion dollars per year. Data compiled by the National Center for Health Statistics reveal a dramatic de cline in deaths from cardiovascular disease in the United States (greater than 20% since 1968). This phenomenon has been the subject of in-depth study. It is clear that the decline is real and not a statistical artifact. The decrease in mortality has been noted in all sections of the country, though the onset and rate of decline varies in different regions of the country. Both primary prevention, through changes in risk factors, and basic and applied research leading to earlier recognition and im proved treatment have contributed to the decline. They do not fully explain the decline. Further research is needed to clarify this issue. Clinical cardiologists have been exposed to a veritable explosion of new knowl edge of mechanisms of cardiovascular disease, development of new improved non-invasive diagnostic techniques, and the pharmacodynamics of agents affect ing the cardiovascular system. This new knowledge results from contributions made by individuals from diverse disciplines including cellular and molecular bi ologists, geneticists, hematologists, cardiologists, and cardiovascular surgeons.
Microscopy Of The Heart
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Author : Lars Kaestner
language : en
Publisher: Springer
Release Date : 2018-12-07
Microscopy Of The Heart written by Lars Kaestner and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-07 with Science categories.
This book provides in depths information on different microscopy approaches and supplies the reader with methods how to untangle highly complex processes involved in physiological and pathophysiological cardiac signaling. Microscopy approaches have established themselves as the quasi gold standard that enables us to appreciate the underlying mechanisms of physiological and pathophysiological cardiac signaling. This book presents the most important microscopy techniques from the level of individual molecule e.g. Förster-Resonance Energy Transfer (FRET), up to cellular and tissue imaging, e.g. electron microscopy (TEM) or light sheet microscopy. The book is intended for graduate students and postdocs in cardiovascular research, imaging and cell biology, pre-clinical and clinical researchers in cardiovascular sciences as well as decision makers of the pharmaceutical industry.
Molecular Biology Of Cardiac Development And Growth
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Author : Paul J.R. Barton
language : en
Publisher: Springer
Release Date : 2013-10-03
Molecular Biology Of Cardiac Development And Growth written by Paul J.R. Barton and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-03 with Science categories.
This is the only book to specifically combine basic information on molecular biology with current thinking in cardiac development. The authors clearly illustrate that molecular biology has already provided a wealth of new approaches to the investigation of cellular processes at the molecular level and is now making a significant contribution to the understanding of the role played by such mechanisms in cardiac development. Furthermore, it is shown that this rapidly-expanding field provides an insight into the molecular events underlying cardiac malformation and disease.