Cartilage
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Cartilage
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Author : Brian K. Hall
language : en
Publisher: Academic Press
Release Date : 2013-10-22
Cartilage written by Brian K. Hall and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.
Cartilage, Volume 3: Biomedical Aspects is a compilation of articles that covers the various aspects of age-related cartilage deterioration, bone disease, and genetic mutation. The book is composed of 10 chapters that highlight different subjects related to the diseases and malformations of cartilage. Relevant topics that are discussed in each chapter include the formation of cartilage outside the confines of the skeleton; aspects of age-related changes in cartilage; tumors that invade cartilage; molecular and biochemical bases of cartilage mutations; and the immunological and bioelectrical properties of cartilage. Physicians, pathologists, orthopedic surgeons, and those working on the human skeletal system will find this text a very good reference material.
Cartilage
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Author : Susanne Grässel
language : en
Publisher: Springer
Release Date : 2017-05-09
Cartilage written by Susanne Grässel and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-09 with Medical categories.
In three Volumes this mini book series presents current knowledge and new perspectives on cartilage as a specialized yet versatile tissue. This third volume provides insight into current and future treatment strategies for repair of cartilage lesions. This book addresses Professors, researchers and PhD students who are interested in musculoskeletal and cartilage pathobiology and tissue-engineering.
Articular Cartilage Tissue Engineering
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Author : Kyriacos A. Athanasiou
language : en
Publisher: Morgan & Claypool Publishers
Release Date : 2010
Articular Cartilage Tissue Engineering written by Kyriacos A. Athanasiou and has been published by Morgan & Claypool Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.
Cartilage injuries in children and adolescents are increasingly observed, with roughly 20% of knee injuries in adolescents requiring surgery. In the US alone, costs of osteoarthritis (OA) are in excess of $65 billion per year (both medical costs and lost wages). Comorbidities are common with OA and are also costly to manage. Articular cartilage's low friction and high capacity to bear load makes it critical in the movement of one bone against another, and its lack of a sustained natural healing response has necessitated a plethora of therapies. Tissue engineering is an emerging technology at the threshold of translation to clinical use. Replacement cartilage can be constructed in the laboratory to recapitulate the functional requirements of native tissues. This book outlines the biomechanical and biochemical characteristics of articular cartilage in both normal and pathological states, through development and aging. It also provides a historical perspective of past and current cartilage treatments and previous tissue engineering efforts. Methods and standards for evaluating the function of engineered tissues are discussed, and current cartilage products are presented with an analysis on the United States Food and Drug Administration regulatory pathways that products must follow to market. This book was written to serve as a reference for researchers seeking to learn about articular cartilage, for undergraduate and graduate level courses, and as a compendium of articular cartilage tissue engineering design criteria. Table of Contents: Hyaline Articular Cartilage / Cartilage Aging and Pathology / In Vitro / Bioreactors / Future Directions
Articular Cartilage
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Author : Kyriacos A. Athanasiou
language : en
Publisher: CRC Press
Release Date : 2017-01-06
Articular Cartilage written by Kyriacos A. Athanasiou and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-06 with Medical categories.
Well-known for their inability to heal, articular cartilage injuries often degenerate inexorably to disastrous impairment. Multitudes of treatments have been devised for this problem, but no satisfactory long-term solutions have been established. Written by world-class experts, Articular Cartilage covers the latest research and advancements related to biology, development, pathology, clinical applications, and tissue engineering. This book is useful for rheumatologists, orthopaedic surgeons, cartilage biologists, and cartilage engineers as well as for professionals working in the orthopaedic and other musculoskeletal industries. This book also belongs in the library of primary care physicians, gerontologists, physical therapists, kinesiologists, and chiropractors. Written at a level that allows accessibility to a wide audience, it provides an interdisciplinary approach that encompasses the breadth and depth of basic science, bioengineering, translational science, and detailed methodologic approaches. The authors examine the major events and signaling molecules that lead to development of articular cartilage from precursor cells, and the changes in cartilage as it matures and ages. They focus on the epidemiology, etiopathogenesis, and therapeutic approaches for cartilage injury and the major arthritides that affect cartilage and the synovial joints such as osteoarthritis, rheumatoid arthritis, and gout. They supply an up-to-date overview of the field of tissue engineering as applied to articular cartilage repair. They examine a number of methods used to assess structure, composition, biology, and biomechanical function. Each chapter contains extensive references to enhance additional study. The book’s comprehensive focus on multiple aspects of articular cartilage sets it apart from other tissue engineering or developmental biology-based books available. It includes important discussions and perspectives on many of the remaining challenges and opportunities in the development and translation of new approaches for treating diseases of articular cartilage. It also provides detailed working protocols for many of the methods used to study articular cartilage, coverage of current treatment options, and business and regulatory aspects of the development of cartilage products. It provides a deeper understanding that will help with the development of new products and clinical applications.
Developing Insights In Cartilage Repair
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Author : Pieter J. Emans
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-10-16
Developing Insights In Cartilage Repair written by Pieter J. Emans and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-16 with Medical categories.
This comprehensive book discusses cartilage repair and all its aspects. These aspects vary from basic insights in cartilage biology and regeneration via MRI, to results of existing cartilage repair techniques and upcoming novel approaches. Fundamental cartilage biology is the topic covered within the first chapters of the book. These chapters not only provide an insight in healthy, damaged and regenerative cartilage but also describe developments in gene therapy and methods to enhance chondrogenesis of stemcells and prevent hypertophic differentiation. There is a huge progress in the possibilities of MR imaging of both healthy, damaged and regenerative cartilage. These developments not only enable better monitoring of cartilage repair but may also unravel the pathophysiology of the development of cartilage defects. Different cartilage repair techniques (e.g. allografts, autologous chondrocytes transplantation [ACT], microfracture), there technical aspects (e.g. developments towards an total arthroscopic approach), pitfalls, and outcomes are reported in the following chapters. In these chapters factors important for the results of cartilage repair such as meniscal repair, patient factors are described. Finally, an overview of novel cartilage repair techniques such as minced cartilage, denovo cartilage and more areas are discussed in this comprehensive addition to the literature.
Bones And Cartilage
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Author : Brian K. Hall
language : en
Publisher: Academic Press
Release Date : 2014-12-23
Bones And Cartilage written by Brian K. Hall and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-23 with Medical categories.
Bones and Cartilage provides the most in-depth review and synthesis assembled on the topic, across all vertebrates. It examines the function, development and evolution of bone and cartilage as tissues, organs and skeletal systems. It describes how bone and cartilage develop in embryos and are maintained in adults, how bone is repaired when we break a leg, or regenerates when a newt grows a new limb, or a lizard a new tail. The second edition of Bones and Cartilage includes the most recent knowledge of molecular, cellular, developmental and evolutionary processes, which are integrated to outline a unified discipline of developmental and evolutionary skeletal biology. Additionally, coverage includes how the molecular and cellular aspects of bones and cartilage differ in different skeletal systems and across species, along with the latest studies and hypotheses of relationships between skeletal cells and the most recent information on coupling between osteocytes and osteoclasts All chapters have been revised and updated to include the latest research. Offers complete coverage of every aspect of bone and cartilage, with updated references and extensive illustrations Integrates development and evolution of the skeleton, as well a synthesis of differentiation, growth and patterning Treats all levels from molecular to clinical, embryos to evolution, and covers all vertebrates as well as invertebrate cartilages Includes new chapters on evolutionary skeletal biology that highlight normal variation and variability, and variation outside the norm (neomorphs, atavisms) Updates hypotheses on the origination of cartilage using new phylogenetic, cellular and genetic data Covers stem cells in embryos and adults, including mesenchymal stem cells and their use in genetic engineering of cartilage, and the concept of the stem cell niche
Cartilage
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Author : Susanne Grässel
language : en
Publisher: Springer
Release Date : 2017-01-25
Cartilage written by Susanne Grässel and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-25 with Medical categories.
In three Volumes this mini book series presents current knowledge and new perspectives on cartilage as a specialized yet versatile tissue. This second volume is dedicated to basic pathologies of the two most common osteoarticular diseases affecting large segments of the Western population, osteoarthritis and chondrodysplasias. This book addresses Professors, researchers and PhD students who are interested in musculoskeletal and cartilage biology and pathobiology.
Mechanobiology
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Author : J. F. Stoltz
language : en
Publisher: IOS Press
Release Date : 2008
Mechanobiology written by J. F. Stoltz and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Articular cartilage categories.
This book covers the proceedings of the Fifth Symposium on Mechanobiology of Cartilage and Chondrocyte. Mechanobiology can be now considered as a vigorous branch of biomechanics, biorheology and physiology mainly concerned with the study of the influence of mechanical forces on cells and tissues and their clinical or therapeutical applications. As we are now in the age of proteomics, genomics and cell micro mechanical approaches, suing methods like laser tweezers or confocal microscopy, mechanobiology brings new challenges. With such new research, mechanobiology promises new diagnostic and therapeutic approaches. In other respect there has been increasing interest over recent years in the fundamental role played by local mechanical parameters in chondrocyte regulations and cartilage dysfunctions as a first step in the development of osteoarthritis. These proceedings are sub-divided into four parts: Theoretical approaches and mechanobiology of chondrocyte; Cartilage and chondrocyte studies; Osteoarthritis: inflammation degradation and clinical approaches; and, Cartilage engineering
Cartilage Molecular Aspects
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Author : Brian K. Hall
language : en
Publisher: CRC Press
Release Date : 1991-06-18
Cartilage Molecular Aspects written by Brian K. Hall and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-06-18 with Medical categories.
Cartilage plays diverse roles as a definitive supporting tissue in some organs, the basis of low friction surfaces in joints, and a transient morphogenetic template during embryogenesis and repair of the skeleton. The versatility of cartilage is derived from the remarkable material properties of its extracellular matrix, the wide spectrum of regulatory systems that influence the synthesis and degradation of the unique molecular constituents of this matrix, and the development and growth of the cells that produce it. This book touches on each of these areas and provides the first comprehensive reviews of the molecular biology of the genes specifying the collagenous and noncollagenous proteins of the cartilage matrix, as well as the biophysical-chemical properties of the matrix that suits it to the various functions it performs. Up-to-date critical reviews of the mineralization and degradation of cartilage matrix, the roles of polypeptide growth and inducing factors, of ions, in the regulation of cartilage growth and development, and the unique requirements of the energy metabolism of cartilage as a nonvascular tissue, make this volume a useful source for concepts and results for the multiple disciplines that play a part in modern cartilage research.
The Illustrative Book Of Cartilage Repair
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Author : Deepak Rajkumar Goyal
language : en
Publisher: Springer Nature
Release Date : 2020-10-26
The Illustrative Book Of Cartilage Repair written by Deepak Rajkumar Goyal and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-26 with Medical categories.
This book employs a wealth of high-quality illustrations to provide the reader with a detailed understanding of the anatomy and the histology of the cartilage, the etiology and the classification of the cartilage lesions, and the numerous techniques employed for cartilage repair. Detailed attention is devoted to healthy cartilage, to each stage in the degenerative process, and to the response of the cartilage to the treatment. Imaging of the damaged and the repaired cartilage, as well as the information on the biomechanics are provided in great detail. The chapters on the techniques cover a wide range of approaches: marrow stimulation techniques, osteochondral cylinder transfer techniques, first, second and third generation autologous chondrocyte implantation techniques, allografts, cell-based therapies, orthobiologic approaches, and the role of 3D printing. The chapters closes with a consideration of the success of rehabilitation devices and the long-term results of cartilage repair.The book will be invaluable for all general orthopaedic and arthroscopic surgeons seeking a deeper knowledge of cartilage science and will help to dispel the confusion that still surrounds the reparative treatment. The authors are recognized experts in the fields of cartilage histology, assessment, classification, and repair.