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Cartilage And Bone Development And Its Disorders


Cartilage And Bone Development And Its Disorders
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Cartilage And Bone Development And Its Disorders


Cartilage And Bone Development And Its Disorders
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Author : Cecilia Camacho-Hübner
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2011

Cartilage And Bone Development And Its Disorders written by Cecilia Camacho-Hübner and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.


Covering recent advances in basic and clinical research In systemic childhood diseases, including cancer, gastrointestinal, pulmonary and cardiac disorders, childhood growth is severely impaired. In addition, almost 400 known genetic diseases inhibit the ability of the growth plate to form new bone, leaving affected children with growth failure and bony deformities which can severely impact their quality of life and may lead to morbidity and early mortality. This book provides a comprehensive review of bone and cartilage development, growth and disease. Focusing on novel treatment strategies, regulatory signals and molecular mechanisms are discussed in relation to the diseases affecting them. Furthermore, novel methodologies in bone and cartilage research based on recent advances in skeletal stem cell biology, cartilage tissue engineering and allele-specific gene silencing is covered. Providing insight into the basic mechanisms of bone growth, structure and metabolism, research methodology, as well as discussing the clinical management of related diseases, this book is of particular value to physicians with a special interest in bone and cartilage biology; in particular endocrinologists and pediatric endocrinologists that see patients with growth disorders, osteoporosis, osteogenesis imperfecta, and skeletal dysplasias.



Primer On The Metabolic Bone Diseases And Disorders Of Mineral Metabolism


Primer On The Metabolic Bone Diseases And Disorders Of Mineral Metabolism
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Author :
language : en
Publisher: John Wiley & Sons
Release Date : 2018-12-06

Primer On The Metabolic Bone Diseases And Disorders Of Mineral Metabolism written by and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-06 with Science categories.


The authoritative reference to bone diseases and disorders of mineral metabolism, revised and updated Now in its ninth edition, The Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism offers an updated and comprehensive guide to bone and mineral health. Since it was first published 30 years ago, the Primer has become the leading reference on the topic. With contributions from noted experts, the text explores basic biological factors of healthy development and disease states and makes the information accessible for clinical interventions. The ninth edition provides concise coverage of the widest possible spectrum of metabolic bone diseases and disorders of mineral metabolism. The new edition of this invaluable reference expands coverage and includes the most recent developments in the field that help to strengthen its usefulness and ensure that the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism maintains its place as the pre-eminent reference on bone and mineral health. This vital resource: Provides the most accurate, up-to-date evidence-based information on basic and clinical bone science Includes more than 10 new chapters and contributions from 300 authors from wide-ranging international research centers Captures the very cutting edge of research covering mineral homeostasis, osteoporosis and other metabolic bone diseases, skeletal measurement technologies, and genetics Presents a new companion website with useful supplementary materials at www.asbmrprimer.com Written for advanced students, clinicians, and researchers working in the field of bone health and disease, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism is the definitive, one-stop reference for anyone working in the field of bone health and disease.



Encyclopedia Of Bone Biology


Encyclopedia Of Bone Biology
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Author :
language : en
Publisher: Academic Press
Release Date : 2020-06-26

Encyclopedia Of Bone Biology written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-26 with Science categories.


Encyclopedia of Bone Biology, Three Volume Set covers hot topics from within the rapidly expanding field of bone biology and skeletal research, enabling a complete understanding of both bone physiology and its relation to other organs and pathophysiology. This encyclopedia will serve as a vital resource for those involved in bone research, research in other fields that cross link with bone, such as metabolism and immunology, and physicians who treat bone diseases. Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from advanced undergraduate students to research professionals. Chapters also explore the latest advances and hot topics that have emerged in recent years, including the Hematopoietic Niche and Nuclear Receptors. In the electronic edition, each chapter will include hyperlinked references and further readings as well as cross-references to related articles. Incorporates perspectives from experts working within the domains of biomedicine, including physiology, pathobiology, pharmacology, immunology, endocrinology, orthopedics and metabolism Provides an authoritative introduction for non-specialists and readers from undergraduate level upwards, as well as up-to-date foundational content for those familiar with the field Includes multimedia features, cross-references and color images/videos



Bone Remodelling And Its Disorders


Bone Remodelling And Its Disorders
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Author : Gregory R Mundy
language : en
Publisher: CRC Press
Release Date : 1999-01-01

Bone Remodelling And Its Disorders written by Gregory R Mundy and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-01-01 with Medical categories.


Abnormalities in bone remodelling occur in some of the most common diseases, including osteoporosis, cancer and Paget's disease, and cause considerable suffering This book bridges the gap between cellular and molecular biology, and pathophysiology and treatment This practical and succinct text will be of interest for all those involved in the study, diagnosis and treatment of bone disease



Pediatric Endocrinology


Pediatric Endocrinology
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Author : Mark A. Sperling
language : en
Publisher: Elsevier Health Sciences
Release Date : 2014-04-10

Pediatric Endocrinology written by Mark A. Sperling and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-10 with Medical categories.


In a single, convenient volume, Pediatric Endocrinology offers complete coverage of all aspects of basic science and clinical practice, ideal for both pediatricians and endocrinologists. Pediatric endocrinology expert Dr. Mark Sperling teams up with world-renowned authors to bring you up to date with the latest key developments in every area of the field, providing invaluable guidance on how your clinical decision making will be affected by today’s technological and scientific advances. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Determine the best possible course for every patient with easy-to-follow algorithms in every clinical chapter. Stay up to date with today’s hottest topics, including neonatal diabetes mellitus, Type II childhood diabetes, molecular endocrinology, and genetics. Explore the impact of today’s advances and challenges, including explosive growth in molecular biology, sophisticated imaging techniques, and an increase in both pediatric diabetes and obesity. Quickly access the information you need with a new, streamlined organization (Concepts, Endocrine Disorders of the Newborn, Endocrine Disorders of Childhood and Adolescence, and Laboratory Tests and Imaging).



Sperling Pediatric Endocrinology E Book


Sperling Pediatric Endocrinology E Book
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Author : Mark A. Sperling
language : en
Publisher: Elsevier Health Sciences
Release Date : 2020-07-22

Sperling Pediatric Endocrinology E Book written by Mark A. Sperling and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-22 with Medical categories.


An ideal resource for both pediatricians and endocrinologists, Sperling's Pediatric Endocrinology, 5th Edition, brings you fully up to date with accelerating research; new discoveries in metabolic, biochemical and molecular mechanisms; and the resulting advances in today's clinical care. The editorial team of world-renowned pediatric endocrinologists led by Dr. Mark Sperling, as well as expert contributing authors, cover comprehensive and current aspects of both basic science and clinical practice. Whether you're preparing for certification or have extensive clinical experience, this detailed, authoritative reference helps you increase your knowledge and determine the best possible course for every patient. - Delivers trusted guidance in every area of the field: including Endocrine Disorders of the Newborn, Endocrine Disorders of Childhood and Adolescence, and Laboratory Tests. - Features new topics such as transgender issues in children and adolescents and endocrinology of pregnancy, the fetus and the placenta. - Offers expert coverage of hot topics such as disorders of sexual development, molecular basis of endocrine disorders, hypoglycemia in newborns and infants; neonatal and other monogenic forms of diabetes; Type I and Type II diabetes and their treatment with new insulins together with the progress in an artificial pancreas and new medications for T2DM in adolescents; the obesity epidemic and role of bariatric surgery; and advances toward personalized medicine. - Includes easy-to-follow algorithms and numerous quick-reference tables and boxes in every clinical chapter, plus interactive questions online for self-assessment. - Offers state-of-the-art information and fresh perspectives from new and award-winning authors in such areas as disorders of growth, multiple endocrine tumors, and puberty and its disorders in girls and boys.



Diseases Of Bones And Joints


Diseases Of Bones And Joints
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Author : Nottidge Charles Macnamara
language : en
Publisher:
Release Date : 1887

Diseases Of Bones And Joints written by Nottidge Charles Macnamara and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1887 with Bones categories.




Robbins Cotran Pathologic Basis Of Disease 10e South Asia Edition 2 Vol Set E Book


Robbins Cotran Pathologic Basis Of Disease 10e South Asia Edition 2 Vol Set E Book
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Author : Vinay Kumar
language : en
Publisher: Elsevier Health Sciences
Release Date : 2020-07-22

Robbins Cotran Pathologic Basis Of Disease 10e South Asia Edition 2 Vol Set E Book written by Vinay Kumar and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-22 with Medical categories.


Readable and highly illustrated, Robbins and Cotran Pathologic Basis of Disease, South Asia Edition presents an in-depth, state-of-the-art overview of human diseases and their cellular and molecular basis. This best-selling text delivers the latest, most essential pathology knowledge in a readable, interesting manner, ensuring optimal understanding of the latest basic science and clinical content. More than 1,000 high-quality photographs and full-color illustrations highlight new information in molecular biology, disease classifications, new drugs and drug therapies, and much more - Provides uniquely authoritative and readable coverage, ideal for USMLE or specialty board preparation, as well as for coursework. - Covers the hot topics you need to know about, including novel therapies for hepatitis C, classification of lymphomas, unfolded protein response, non-apoptotic pathways of cell death, coronavirus infections, liquid biopsy for cancer detection, regulation of iron absorption, clonal hematopoiesis and atherosclerosis, thrombotic microangiopathies, heparin-induced thrombocytopenias, inflammatory myopathies, genetic tools for treatment of cystic fibrosis, and many more. - Uses an outstanding full-color, user-friendly design to simplify your study and quickly direct you to the information you need to know, with learning features such as boldface overviews at the beginning of each section, key concepts boxes, suggested readings, schematic diagrams that illustrate complex concepts, and new gross and microscopic figures for clarity of morphology. - Brings you up to date with the latest information in molecular and genetic testing, mechanisms of disease, personalized medicine and its impact on treatment of human diseases, the role of microbiome and metabolome in non-communicable diseases, and much more. - New to the edition from South Asia - Neoplasia • Infectious Diseases • Diseases of White Blood Cells, Lymph Nodes, Spleen, and Thymus • Red Blood Cell and Bleeding Disorders • The Lung • Head and Neck • The Gastrointestinal Tract • Liver and Gallbladder • The Kidney • The Breast • The Endocrine System • The Skin • The Central Nervous System • The Eye • Transfusion Medicine



Robbins Cotran Pathologic Basis Of Disease E Book


Robbins Cotran Pathologic Basis Of Disease E Book
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Author : Vinay Kumar
language : en
Publisher: Elsevier Health Sciences
Release Date : 2020-05-18

Robbins Cotran Pathologic Basis Of Disease E Book written by Vinay Kumar and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-18 with Medical categories.


Readable and highly illustrated, Robbins and Cotran Pathologic Basis of Disease, 10th Edition presents an in-depth, state-of-the-art overview of human diseases and their cellular and molecular basis. This best-selling text delivers the latest, most essential pathology knowledge in a readable, interesting manner, ensuring optimal understanding of the latest basic science and clinical content. More than 1,000 high-quality photographs and full-color illustrations highlight new information in molecular biology, disease classifications, new drugs and drug therapies, and much more. This superb learning package also includes an enhanced eBook with a full complement of ancillary content on Student Consult. - Provides uniquely authoritative and readable coverage, ideal for USMLE or specialty board preparation, as well as for coursework. - Covers the hot topics you need to know about, including novel therapies for hepatitis C, classification of lymphomas, unfolded protein response, non-apoptotic pathways of cell death, coronavirus infections, liquid biopsy for cancer detection, regulation of iron absorption, clonal hematopoiesis and atherosclerosis, thrombotic microangiopathies, heparin-induced thrombocytopenias, inflammatory myopathies, genetic tools for treatment of cystic fibrosis, and many more. - Uses an outstanding full-color, user-friendly design to simplify your study and quickly direct you to the information you need to know, with learning features such as boldface overviews at the beginning of each section, key concepts boxes, suggested readings, schematic diagrams that illustrate complex concepts, and new gross and microscopic figures for clarity of morphology. - Brings you up to date with the latest information in molecular and genetic testing, mechanisms of disease, personalized medicine and its impact on treatment of human diseases, the role of microbiome and metabolome in non-communicable diseases, and much more. - Provides access to a wealth of interactive ancillaries online: pathology case studies, videos, self-assessment questions, Targeted Therapy boxes that discuss drug therapy for specific diseases, interactive cases, and more. - Evolve Instructor site with an image and test bank is available to instructors through their Elsevier sales rep or via request at https://evolve.elsevier.com.



Genetics Of Bone Biology And Skeletal Disease


Genetics Of Bone Biology And Skeletal Disease
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Author : Rajesh V. Thakker
language : en
Publisher: Academic Press
Release Date : 2017-10-31

Genetics Of Bone Biology And Skeletal Disease written by Rajesh V. Thakker and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-31 with Science categories.


Genetics of Bone Biology and Skeletal Disease, Second Edition, is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid and related disorders, and vitamin D and renal disorders. The first section is specifically devoted to providing an overview of bone biology and structure, joint and cartilage biology, principles of endocrine regulation of bone, and the role of neuronal regulation and energy homeostasis. The second section reviews the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, copy number variation, prospects of gene therapy, pharmacogenomics, genetic testing and counseling, as well as the generation and utilizing of mouse models. The third section details advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasias, and rarer bone disorders. The fourth section highlights the central role of the parathyroids in calcium and skeletal homeostasis by reviewing the molecular genetics of: hyperparathyroidism, hypoparathyrodism, endocrine neoplasias, and disorders of the PTH and calcium-sensing receptors. The fifth section details molecular and cellular advances across associated renal disorders such as vitamin D and rickets. - Identifies and analyzes the genetic basis of bone disorders in humans and demonstrates the utility of mouse models in furthering the knowledge of mechanisms and evaluation of treatments - Demonstrates how the interactions between bone and joint biology, physiology, and genetics have greatly enhanced the understanding of normal bone function as well as the molecular pathogenesis of metabolic bone disorders - Summarizes the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder