Case For Interferon
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Case For Interferon
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Author : Joseph Cummins
language : en
Publisher: Simon and Schuster
Release Date : 2021-01-05
Case For Interferon written by Joseph Cummins and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-05 with Science categories.
Touted as a potential breakthrough cancer therapy in the 1980s by the scientific community and publications such as TIME and Newsweek magazine, the reputation of interferon has not lived up to its early promise. Interferons are small proteins with anti-viral and anti-cancer effects, which have the power to modulate the functioning of the immune system. But Dr. Joseph Cummins, an early interferon pioneer, holder of sixteen US medical patents, author of more than sixty scientific publications, as well as having taught veterinary medicine at the University of Missouri, University of Illinois, and Texas A & M University, argues that the current thinking on interferon is fundamentally flawed. Interferon is created in small quantities in the body in response to infection, and seems to work best at these low dosages. However, the public health cowboys, working under the assumption that anything good in tiny amounts must be better in massive amounts, pursued exactly the wrong strategy. High-dose interferon does not work in the body and may even cause problems. The first remarkable results for interferon and the flu were reported by the Soviets in the 1970s, but Western medicine discounted these findings because they believed the dosages were so low they couldn’t possibly be effective. In the 1980s, when interferon was expensive to produce and only small quantities could be manufactured, the results were remarkable. Dr. Cummins was an early pioneer of low-dose interferon, and his remarkable findings among animals led to collaborations with medical doctors for human trials, even going so far as Africa at the height of the HIV-AIDS epidemic. Cummins reviews the evidence for this inexpensive, safe treatment and makes an eloquent argument for medical science to take another look at interferon to tackle today’s most challenging health conditions, including COVID-19.
The Interferon System
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Author : W.E. Stewart II
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17
The Interferon System written by W.E. Stewart II and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Medical categories.
This book is an update of Interferon, published in 1969 by Dr. Jan Vilcek. The field of interferon research has since expanded from its former narrow treatment of interferon strictly as an antiviral substance, such that The Interferon System now encompasses cellular modulations ranging from immune alterations to cell proliferative restrictions to antitumor activities. The steadily increasing number of these non-antiviral functions of interferons emphasizes the need for a comprehensive - and critical - review of the entire literature of interferon studies. The text, with its supporting bibliography, provides complete coverage of interferon research. A newcomer to the area should find here all the informa tion necessary to understand why interferon, which has been studied for more than twenty years and which originally stirred excitement over its clinical pros pects, is still inspiring speculation about this potential. For those already fa miliar with the seemingly perpetual clinical promise of interferon, this volume should serve as a valuable reference source, the largest bibliography on the subject ever to appear under one cover. Clearly, this book should be considered only as an introduction to the topic and as a reference source; most questions about the interferon system are still unanswered - even unasked. Hopefully this summation and critical evalua tion of work done to date will stimulate and facilitate further progress. William E. Stewart II New York, N. Y., February 1979 Contents I. Introduction ............................................................. .
Frontiers In Cancer Research For The Elderly
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Author : United States. Congress. House. Select Committee on Aging
language : en
Publisher:
Release Date : 1979
Frontiers In Cancer Research For The Elderly written by United States. Congress. House. Select Committee on Aging and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Cancer categories.
Interferon And Nonviral Pathogens
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Author : Gerald. I. Bryne
language : en
Publisher: CRC Press
Release Date : 2021-05-30
Interferon And Nonviral Pathogens written by Gerald. I. Bryne and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-30 with Medical categories.
This book explores the important role of the interferons in infections due to nonviral intracellular pathogens. It deals with the induction of interferons by a variety of intracellular microorganisms and the effects of interferons on the host cells and the microorganisms.
Interferon And Cancer
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Author : Karol Sikora
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Interferon And Cancer written by Karol Sikora and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
Interferon was first discovered in 1957. Over the last five years it has become almost a household word. Many believe it to be a drug with already proven efficacy against cancer and viral infection. The media has distorted any cool scientific view of the data available. We have learned much about the complexity of the interferon system. We know some of the switches involved in interferon gene expression and its secretion by virally and immune stimulated cells. We also know that it binds to a cell surface receptor, mediating its complex effects on target cells by a series of second messengers. The advent of the new techniques of modern molecular biology, such as monoclonal antibodies and gene cloning, has had tremendous impact on the rate of acquisition of knowledge. Such techniques have provided us with almost unlimited quantities of highly purified interferon for clinical trial in patients with a spectrum of infectious and malignant diseases. The information we have gathered raises many more questions. Why should there be several families of interferon genes? What is their true physiolo gical role? How are they interrelated functionally? Interferon is clearly a cellular hormone providing a means of communication between cells. ~fhether it has clinical value in the management of patients with diseased cells remains to be seen. This book sum marises our current knowledge of interferons as possible an- cancer agents. It is clear interferon is no penicillin for cancer.
Interferon The 50th Anniversary
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Author : Paula M. Pitha
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-09-11
Interferon The 50th Anniversary written by Paula M. Pitha and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-11 with Medical categories.
A vital text for researchers and clinicians in the fields of virology and oncology alike, this book is a comprehensive guide to one of medicine’s most important tools that covers the most recent research. Important insights have been made in recent months that are challenging the accepted concept of the critical role of dsRNA in IFN induction. Recent work with genetically modified mice seems to confirm the original idea that interferon is the first cellular defense against viral infection.
Consultation Liaison Psychiatry In Japan
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Author : I. Fukunishi
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2001-07
Consultation Liaison Psychiatry In Japan written by I. Fukunishi and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-07 with Medical categories.
Despite great advances in medical technology, the stresses of illness persist, resulting in a significant prevalence of comorbid psychiatric disorders in hospital and ambulatory medical settings. Consultation-liaison psychiatry is the subspecialty of psychiatry that focuses upon these issues. It has become a link between mental health disciplines and other fields of health care all over the world. This volume documents the vibrant energy and productivity of Japanese consultation-liaison psychiatrists who have developed a new biopsychosocial model for the treatment of patients with a variety of serious diseases. It begins with an overview on the historical background and the present issues in Japan. Further articles deal with psychiatric problems in transplant medicine, psychonephrology, psychooncology and HIV/AIDS. Finally drug-induced psychosis and psychosomatic problems of diabetes patients are discussed. The book will be useful to any physician or mental health care professional who works with the medically ill. It demonstrates the wide range of knowledge and treatment options available to mental health care professionals to intervene when dealing with patients suffering of a serious disease.
Departments Of Labor And Health Education And Welfare And Related Agencies Appropriations For Fiscal Year 1980
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Author : United States. Congress. Senate. Committee on Appropriations. Subcommittee on Departments of Labor, and Health, Education, and Welfare, and Related Agencies
language : en
Publisher:
Release Date : 1979
Departments Of Labor And Health Education And Welfare And Related Agencies Appropriations For Fiscal Year 1980 written by United States. Congress. Senate. Committee on Appropriations. Subcommittee on Departments of Labor, and Health, Education, and Welfare, and Related Agencies and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with United States categories.
Meyler S Side Effects Of Cardiovascular Drugs
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Author : Jeffrey K. Aronson
language : en
Publisher: Elsevier
Release Date : 2009-03-02
Meyler S Side Effects Of Cardiovascular Drugs written by Jeffrey K. Aronson and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-02 with Medical categories.
Elsevier now offers a series of derivative works based on the acclaimed Meylers Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing physician or health care clinician. Each year, heart disease kills more people than cancer. Patients are treated by a variety of specialists and primary care practitioners, depending on the organ system involved. This volume enables practitioners to assess the adverse effects of the complete range of drugs used in cardiovascular medicine, including antihypertensive drugs, and drugs used in the treatment of heart failure, angina, angina pectoris, and cardiac arrhythmia and enable practitioners to prescribe preventative treatments with medications such as blood pressure reducers, aspirin, and cholesterol-lowering drugs, as well as drugs used for more aggressive therapy.The material is drawn from the 15th edition of the internationally renowned encyclopedia, Meyler's Side Effects of Drugs, and the latest volumes in the companion series, Side Effects of Drugs Annuals. Drug names have usually been designated by their recommended or proposed International Non-proprietary Names (rINN or pINN); when those are not available, clinical names have been used. In some cases, brand names have been used.This volume is critical for any health professional involved in the administration of cardiovascular mediations. - Surpasses the Physician's Desk Reference © by including clinical case studies and independent expert analysis - Complete index of drug names - Most complete cross referencing of drug-drug interactions available - Extensive references to primary and secondary literature - Also includes information on adverse effects in pregnancy The book is divided into six sections: - Drugs used to treat hypertension, heart failure and angina pectoris - Diuretics – a general introduction to their adverse effects, followed by monographs on individual drugs - Antidysrhythmic drugs - a general introduction to their adverse effects, followed by monographs on individual drugs - Drugs that act on the cerebral and peripheral circulations - Anticoagulants, thrombolytic agents, and anti-platelet drugs - Cardiovascular adverse effects of non-cardiovascular drugs
Departments Of Labor And Health Education And Welfare Appropriations For 1980
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Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor and Health, Education, and Welfare
language : en
Publisher:
Release Date : 1979
Departments Of Labor And Health Education And Welfare Appropriations For 1980 written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor and Health, Education, and Welfare and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with categories.